BRPI0909691A2 - Composto, método para preparar um composto, e, composição farmacêutica - Google Patents

Composto, método para preparar um composto, e, composição farmacêutica

Info

Publication number
BRPI0909691A2
BRPI0909691A2 BRPI0909691-4A BRPI0909691A BRPI0909691A2 BR PI0909691 A2 BRPI0909691 A2 BR PI0909691A2 BR PI0909691 A BRPI0909691 A BR PI0909691A BR PI0909691 A2 BRPI0909691 A2 BR PI0909691A2
Authority
BR
Brazil
Prior art keywords
compound
preparing
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
BRPI0909691-4A
Other languages
English (en)
Inventor
Sung Oh Ahn
Chan Hee Park
Jun Hwan Im
Soon Ok Lee
Kyoung June Lee
Seong Wook Cho
Kwang Seok Ko
Sun Young Han
Won Ii Lee
Original Assignee
C & C Res Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C & C Res Lab filed Critical C & C Res Lab
Publication of BRPI0909691A2 publication Critical patent/BRPI0909691A2/pt
Publication of BRPI0909691A8 publication Critical patent/BRPI0909691A8/pt
Publication of BRPI0909691B1 publication Critical patent/BRPI0909691B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0909691-4A 2008-03-31 2009-03-31 Composto derivado de heterociclo, método para preparar um composto, e, composição farmacêutica BRPI0909691B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2008-0030067 2008-03-31
KR20080030067 2008-03-31
PCT/KR2009/001659 WO2009145456A2 (ko) 2008-03-31 2009-03-31 헤테로사이클 유도체

Publications (3)

Publication Number Publication Date
BRPI0909691A2 true BRPI0909691A2 (pt) 2015-08-04
BRPI0909691A8 BRPI0909691A8 (pt) 2018-01-02
BRPI0909691B1 BRPI0909691B1 (pt) 2021-07-20

Family

ID=41377713

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909691-4A BRPI0909691B1 (pt) 2008-03-31 2009-03-31 Composto derivado de heterociclo, método para preparar um composto, e, composição farmacêutica

Country Status (23)

Country Link
US (1) US8394792B2 (pt)
EP (1) EP2266989B1 (pt)
JP (1) JP5314123B2 (pt)
KR (1) KR101250297B1 (pt)
CN (1) CN102015726B (pt)
AU (1) AU2009252166B9 (pt)
BR (1) BRPI0909691B1 (pt)
CA (1) CA2718709C (pt)
DK (1) DK2266989T3 (pt)
EA (1) EA018521B1 (pt)
ES (1) ES2552311T3 (pt)
HR (1) HRP20151098T1 (pt)
HU (1) HUE026261T2 (pt)
IL (1) IL208203A (pt)
MX (1) MX2010010366A (pt)
MY (1) MY155517A (pt)
NZ (1) NZ587880A (pt)
PL (1) PL2266989T3 (pt)
PT (1) PT2266989E (pt)
SI (1) SI2266989T1 (pt)
TW (2) TWI500622B (pt)
WO (1) WO2009145456A2 (pt)
ZA (1) ZA201006475B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201106814D0 (en) 2011-04-21 2011-06-01 Astex Therapeutics Ltd New compounds
US20130090334A1 (en) * 2011-10-05 2013-04-11 Hoffmann-La Roche Inc Azabenzoxazine derivatives as crac modulators
RU2014134845A (ru) * 2012-01-27 2016-03-20 Тейдзин Фарма Лимитед Терапевтическое средство против диабета
US20140034475A1 (en) * 2012-04-06 2014-02-06 Deka Products Limited Partnership Water Vapor Distillation Apparatus, Method and System
JP5805613B2 (ja) * 2012-11-16 2015-11-04 株式会社神戸製鋼所 改質石炭の製造方法及び改質石炭製造装置
CN103936762B (zh) * 2013-01-17 2016-02-24 上海汇伦生命科技有限公司 吗啉并喹啉类化合物，其制备方法和用途
CN103664764A (zh) * 2013-12-06 2014-03-26 常熟市联创化学有限公司 一种3-氨基-2-羟基吡啶的制备方法
US10087151B2 (en) 2014-01-09 2018-10-02 The J. David Gladstone Institutes, A Testimentary Trust Established Under The Will Of J. David Gladstone Substituted benzoxazine and related compounds
CN106458970B (zh) * 2014-05-13 2019-09-13 帝人制药株式会社 吡啶衍生物的多晶形体及其制造方法
ES2865182T3 (es) 2014-12-29 2021-10-15 Nippon Chemiphar Co Inhibidor de URAT1
AR105911A1 (es) 2015-09-03 2017-11-22 Forma Therapeutics Inc Inhibidores de hdac8 bicíclicos fusionados [6,6]
JP6898330B2 (ja) 2015-12-28 2021-07-07 シャンハイ フォチョン ファーマシューティカル カンパニー リミテッド インドリジン誘導体、組成物、及び使用方法
CN108084186B (zh) 2016-11-16 2021-06-25 江苏新元素医药科技有限公司 Urat1抑制剂及其应用
WO2018090921A1 (zh) 2016-11-16 2018-05-24 江苏新元素医药科技有限公司 Urat1抑制剂及其应用
TWI837089B (zh) * 2017-05-25 2024-04-01 南韓商Ｊｗ製藥公司 製備雜環衍生化合物之方法、包括該化合物之組成物及該化合物之水合物
WO2018237370A1 (en) 2017-06-23 2018-12-27 Accro Bioscience Inc. Heteroaryl compounds as inhibitors of necrosis, composition and method using the same
CN109111464B (zh) 2017-06-23 2021-02-26 爱科诺生物医药股份有限公司 一种具有细胞坏死抑制活性的杂环化合物
CN112979661B (zh) 2018-01-19 2022-05-17 苏州信诺维医药科技股份有限公司 杂环化合物、制备方法及其在医药上的应用
CN108558906A (zh) * 2018-05-21 2018-09-21 日照市普达医药科技有限公司 一种治疗白内障药物苯并吩噁嗪类化合物及其制备方法
PE20211089A1 (es) 2018-08-13 2021-06-14 Hoffmann La Roche Nuevos compuestos heterociclicos como inhibidores de la monoacilglicerol lipasa
WO2020104494A1 (en) 2018-11-22 2020-05-28 F. Hoffmann-La Roche Ag New heterocyclic compounds
WO2020253659A1 (en) * 2019-06-17 2020-12-24 Fochon Pharmaceuticals, Ltd. Heterocyclic derivatives and use thereof
TWI894285B (zh) * 2020-06-04 2025-08-21 英屬開曼群島商百濟神州有限公司 作為IAP拮抗劑的吡啶並[2,3-b][1,4]噁嗪或四氫吡啶並[2,3-b][1,4]氧氮呯
CN113880774B (zh) * 2020-07-02 2023-12-08 沈阳中化农药化工研发有限公司 一种苯基异恶唑啉类化合物的制备方法
CN111841896B (zh) * 2020-08-06 2022-10-18 武汉工程大学 一种苯并杂环羟肟酸类捕收剂及其制备方法和应用
WO2022169974A1 (en) 2021-02-05 2022-08-11 Nexys Therapeutics, Inc. Inhibitors of urat1 and pharmaceutical uses thereof
CN119059989A (zh) * 2023-05-31 2024-12-03 中国药科大学 Urat1抑制剂及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002220389A (ja) * 2001-01-26 2002-08-09 Hokko Chem Ind Co Ltd ピリジルベンズオキサジン誘導体、除草剤および中間体
AR051780A1 (es) * 2004-11-29 2007-02-07 Japan Tobacco Inc Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos
JP3988832B2 (ja) 2004-11-29 2007-10-10 日本たばこ産業株式会社 窒素含有縮合環化合物及びその用途
US20060177646A1 (en) * 2005-02-09 2006-08-10 Detlef Burgard Method for producing shatterproof glass panels and casting resin molding
US20070197512A1 (en) * 2006-01-27 2007-08-23 Japan Tobacco Inc. Carboxylic Acid Compounds and Use Thereof
TWI385161B (zh) * 2006-02-02 2013-02-11 Mitsubishi Tanabe Pharma Corp 含氮雜雙環化合物
KR20080093123A (ko) * 2006-02-13 2008-10-20 에프. 호프만-라 로슈 아게 당뇨병 치료용 헤테로바이사이클릭 설폰아마이드 유도체
US20080064871A1 (en) * 2006-05-26 2008-03-13 Japan Tobacco Inc. Production Method of Nitrogen-Containing Fused Ring Compounds
US7960377B2 (en) * 2008-03-28 2011-06-14 Cara Therapeutics, Inc. Substituted pyridoxazines

Also Published As

Publication number Publication date
BRPI0909691A8 (pt) 2018-01-02
JP5314123B2 (ja) 2013-10-16
WO2009145456A3 (ko) 2010-01-21
CA2718709C (en) 2016-08-09
HRP20151098T1 (hr) 2016-01-01
EP2266989A4 (en) 2011-10-12
JP2011516468A (ja) 2011-05-26
DK2266989T3 (en) 2015-11-23
MX2010010366A (es) 2010-11-30
KR101250297B1 (ko) 2013-04-03
WO2009145456A2 (ko) 2009-12-03
SI2266989T1 (sl) 2015-12-31
KR20110005688A (ko) 2011-01-18
US20110028467A1 (en) 2011-02-03
TWI613203B (zh) 2018-02-01
EP2266989B1 (en) 2015-09-02
HK1148283A1 (en) 2011-09-02
HUE026261T2 (en) 2016-06-28
NZ587880A (en) 2012-06-29
TW201522347A (zh) 2015-06-16
EA018521B1 (ru) 2013-08-30
EA201071144A1 (ru) 2011-06-30
IL208203A (en) 2016-06-30
PL2266989T3 (pl) 2016-04-29
US8394792B2 (en) 2013-03-12
ES2552311T3 (es) 2015-11-27
TW201000488A (en) 2010-01-01
ZA201006475B (en) 2011-10-26
MY155517A (en) 2015-10-30
AU2009252166A1 (en) 2009-12-03
CA2718709A1 (en) 2009-12-03
IL208203A0 (en) 2010-12-30
BRPI0909691B1 (pt) 2021-07-20
AU2009252166B2 (en) 2013-10-10
AU2009252166B9 (en) 2014-02-13
TWI500622B (zh) 2015-09-21
PT2266989E (pt) 2015-11-23
EP2266989A2 (en) 2010-12-29
CN102015726B (zh) 2014-07-23
CN102015726A (zh) 2011-04-13

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: A CLASSIFICACAO ANTERIOR ERA: C07D 498/04

Ipc: C07D 498/04 (2006.01), A61P 13/04 (2006.01), A61P

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/03/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.