BRPI0821087A2 - Preparação externa para a pele. - Google Patents
Preparação externa para a pele.Info
- Publication number
- BRPI0821087A2 BRPI0821087A2 BRPI0821087-0A BRPI0821087A BRPI0821087A2 BR PI0821087 A2 BRPI0821087 A2 BR PI0821087A2 BR PI0821087 A BRPI0821087 A BR PI0821087A BR PI0821087 A2 BRPI0821087 A2 BR PI0821087A2
- Authority
- BR
- Brazil
- Prior art keywords
- skin
- external preparation
- preparation
- external
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/044—Suspensions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/60—Particulates further characterized by their structure or composition
- A61K2800/65—Characterized by the composition of the particulate/core
- A61K2800/652—The particulate/core comprising organic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007317631 | 2007-12-07 | ||
| JP2008309771A JP4341983B2 (ja) | 2007-12-07 | 2008-12-04 | 皮膚外用剤 |
| PCT/JP2008/072201 WO2009072629A1 (ja) | 2007-12-07 | 2008-12-05 | 皮膚外用剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0821087A2 true BRPI0821087A2 (pt) | 2015-06-16 |
Family
ID=40717807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0821087-0A BRPI0821087A2 (pt) | 2007-12-07 | 2008-12-05 | Preparação externa para a pele. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100316581A1 (pt) |
| EP (1) | EP2233154A4 (pt) |
| JP (1) | JP4341983B2 (pt) |
| KR (1) | KR101591672B1 (pt) |
| CN (1) | CN101918031A (pt) |
| AU (1) | AU2008332297B2 (pt) |
| BR (1) | BRPI0821087A2 (pt) |
| RU (1) | RU2010128073A (pt) |
| TW (1) | TWI438007B (pt) |
| WO (1) | WO2009072629A1 (pt) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4646269B2 (ja) * | 2009-03-31 | 2011-03-09 | 株式会社資生堂 | 皮膚外用剤 |
| TWI499432B (zh) * | 2009-09-17 | 2015-09-11 | Shiseido Co Ltd | Skin external use |
| JP4824121B2 (ja) | 2009-09-17 | 2011-11-30 | 株式会社 資生堂 | 皮膚外用剤 |
| JP5712010B2 (ja) * | 2010-03-24 | 2015-05-07 | 第一三共ヘルスケア株式会社 | ビタミンd類が安定化された化粧用又は医薬用外用組成物 |
| JP5528875B2 (ja) * | 2010-03-26 | 2014-06-25 | 日本メナード化粧品株式会社 | 透明液状皮膚外用剤 |
| EP2692331A4 (en) * | 2011-03-30 | 2014-11-26 | Fujifilm Corp | CAROTENOID-CONTAINING COMPOSITION AND METHOD FOR PRODUCING SAME |
| US11065206B2 (en) * | 2011-06-29 | 2021-07-20 | Avidas Pharmaceuticals, LLC | Topical formulations including lipid microcapsule delivery vehicles and their uses |
| JP5865622B2 (ja) * | 2011-08-01 | 2016-02-17 | 昭和電工株式会社 | 皮膚外用剤およびその製造方法 |
| JP5865623B2 (ja) * | 2011-08-01 | 2016-02-17 | 昭和電工株式会社 | 皮膚外用剤およびその製造方法 |
| WO2013073620A1 (ja) | 2011-11-18 | 2013-05-23 | 富士フイルム株式会社 | カロチノイド含有組成物及びその製造方法 |
| CN104203205B (zh) | 2012-03-22 | 2017-06-23 | 富士胶片株式会社 | 透明性高的乳化组合物及透明性高的化妆料 |
| JP6222894B2 (ja) * | 2012-03-30 | 2017-11-01 | 小林製薬株式会社 | 表皮肥厚促進剤 |
| CN104379122B (zh) * | 2012-09-28 | 2018-10-26 | 富士胶片株式会社 | 化妆品和含有甘草次酸衍生物的乳化组合物 |
| JP6082981B2 (ja) * | 2012-12-17 | 2017-02-22 | 株式会社トキワ | 水中油型乳化固形化粧料 |
| JP2014122193A (ja) * | 2012-12-21 | 2014-07-03 | L'oreal Sa | 油、非イオン界面活性剤及びビタミンb3を含む化粧品組成物 |
| JP6592233B2 (ja) * | 2013-12-25 | 2019-10-16 | ロート製薬株式会社 | 皮膚外用組成物 |
| CA2937213A1 (en) * | 2014-01-28 | 2015-08-06 | Resdevco Research And Development Co. Ltd. | Composition comprising xylitol and cholecalciferol for topical treatment of skin and mucous membranes |
| JP6415156B2 (ja) * | 2014-07-23 | 2018-10-31 | 小林製薬株式会社 | 外用組成物 |
| JP5982070B1 (ja) * | 2014-10-09 | 2016-08-31 | 株式会社メディプロデュース | まつ毛用洗浄剤 |
| US11806412B2 (en) | 2014-10-31 | 2023-11-07 | Shiseido Company, Ltd. | Oil-in-water emulsion sunscreen cosmetic |
| US20170348261A1 (en) * | 2014-12-26 | 2017-12-07 | Nipro Corporation | Medical dermatological preparation for external use |
| JP6498446B2 (ja) * | 2015-01-13 | 2019-04-10 | 日本メナード化粧品株式会社 | 透明化粧料 |
| JP6574329B2 (ja) * | 2015-01-29 | 2019-09-11 | 株式会社日清製粉グループ本社 | 食用油脂の製造方法 |
| JP6798149B2 (ja) * | 2015-06-12 | 2020-12-09 | 大正製薬株式会社 | タウリン含有組成物 |
| JP6639892B2 (ja) * | 2015-12-15 | 2020-02-05 | オリザ油化株式会社 | γ−オリザノール可溶化液体組成物 |
| CN105769622A (zh) * | 2016-04-22 | 2016-07-20 | 广西壮族自治区林业科学研究院 | 一种干性皮肤护理用精华油及其制备方法 |
| WO2017194486A1 (en) | 2016-05-12 | 2017-11-16 | Unilever Plc | Method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors |
| JP6920031B2 (ja) * | 2016-06-30 | 2021-08-18 | 小林製薬株式会社 | 慢性角化型湿疹改善剤 |
| JP7182761B2 (ja) * | 2017-02-28 | 2022-12-05 | 株式会社ピカソ美化学研究所 | パール剤およびパール感を有する化粧料 |
| JP6966359B2 (ja) * | 2017-03-08 | 2021-11-17 | 株式会社コーセー | 油性固形化粧料 |
| JP6847728B2 (ja) * | 2017-03-24 | 2021-03-24 | 株式会社コーセー | 皮膚外用剤又は化粧料 |
| GB201712844D0 (en) * | 2017-08-10 | 2017-09-27 | Croda Int Plc | Emulsifier system, personal care product, method and use |
| JP2019131524A (ja) * | 2018-02-01 | 2019-08-08 | 株式会社コーセー | 化粧料及び皮膚外用剤 |
| US20240115487A1 (en) * | 2019-10-14 | 2024-04-11 | Lubrizol Advanced Materials, Inc | Water-resistant and/or photoprotective Compositions Comprising Non-Solubilized Micronized Waxes |
| WO2021162074A1 (ja) * | 2020-02-14 | 2021-08-19 | 株式会社コーセー | 水性化粧料 |
| WO2022165231A1 (en) * | 2021-01-28 | 2022-08-04 | Crystal, Inc. – Pmc | Oil in water wax emulsion composition |
| JP2023157265A (ja) * | 2022-04-14 | 2023-10-26 | 花王株式会社 | 乳化化粧料 |
| CN114939079B (zh) * | 2022-05-19 | 2024-04-23 | 上海奥利实业有限公司 | 一种视黄醇及其衍生物包裹体的制备方法及其应用 |
| CN120265258A (zh) * | 2022-12-28 | 2025-07-04 | 株式会社资生堂 | 具有高保湿效果的组合物 |
| JP7633712B2 (ja) * | 2023-05-12 | 2025-02-20 | アピ株式会社 | 外用組成物 |
| JP2025099708A (ja) * | 2023-12-22 | 2025-07-03 | 小林製薬株式会社 | 外用組成物 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU87457A1 (fr) | 1989-02-24 | 1990-09-19 | Oreal | Utilisation,comme composition cosmetique pour cheveux,d'une microdispersion de cire,et procede de traitement des cheveux avec une telle composition |
| FR2666014B1 (fr) | 1990-08-23 | 1994-10-28 | Oreal | Composition cosmetique pour cheveux contenant un polymere filmogene et une silicone incorpores dans une microdispersion de cire, et procede de traitement cosmetique. |
| JP3502762B2 (ja) | 1997-02-25 | 2004-03-02 | 日清オイリオ株式会社 | 油性組成物及びその製造方法 |
| JP3639715B2 (ja) | 1997-03-21 | 2005-04-20 | 株式会社資生堂 | ワックスの微細分散組成物および毛髪化粧料ならびにつや出し剤 |
| KR100562977B1 (ko) * | 1997-03-21 | 2006-06-22 | 가부시키가이샤 시세이도 | 왁스의 미세분산 조성물 및 모발 화장료, 광택제 |
| JP3949810B2 (ja) | 1998-03-18 | 2007-07-25 | 株式会社資生堂 | ワックスの微細分散組成物および毛髪化粧料ならびにつや出し剤 |
| JP3600436B2 (ja) | 1998-03-31 | 2004-12-15 | 株式会社資生堂 | 水中油型毛髪化粧料 |
| DE19837191A1 (de) * | 1998-08-17 | 2000-02-24 | Henkel Kgaa | Kosmetische und dermatologische Hautbehandlungsmittel |
| US6761903B2 (en) * | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
| EP1408924A1 (en) * | 1999-07-08 | 2004-04-21 | International Flora Technologies Ltd. | Stabilized ascorbic acid, composition, and method of use |
| US20020168335A1 (en) * | 2000-12-12 | 2002-11-14 | Nathalie Collin | Cosmetic composition comprising a wax and a polymer |
| DE10102005A1 (de) * | 2001-01-18 | 2002-07-25 | Cognis Deutschland Gmbh | Perlglanzmittel |
| FR2829693B1 (fr) * | 2001-09-20 | 2004-02-27 | Oreal | Creme cosmetique moussante |
| JP2004083437A (ja) * | 2002-08-23 | 2004-03-18 | Shiseido Co Ltd | 局所麻酔用固形状組成物 |
| DE10300506A1 (de) * | 2003-01-08 | 2004-07-22 | Cognis Deutschland Gmbh & Co. Kg | Wachsdispersionen |
| WO2005097056A1 (de) * | 2004-04-05 | 2005-10-20 | Cognis Ip Management Gmbh | Wachmischung auf basis von partialglyceriden und pentaerythritestern |
| DE102004017222A1 (de) * | 2004-04-05 | 2005-10-20 | Cognis Ip Man Gmbh | Sensorische Wachse für kosmetische und/oder pharmazeutische Formulierungen |
| GB0704709D0 (en) * | 2007-03-12 | 2007-04-18 | Croda Singapore P L | Dispersion, gel and emulsification system |
-
2008
- 2008-12-04 JP JP2008309771A patent/JP4341983B2/ja active Active
- 2008-12-05 CN CN2008801196182A patent/CN101918031A/zh active Pending
- 2008-12-05 RU RU2010128073/15A patent/RU2010128073A/ru unknown
- 2008-12-05 US US12/745,906 patent/US20100316581A1/en not_active Abandoned
- 2008-12-05 AU AU2008332297A patent/AU2008332297B2/en not_active Ceased
- 2008-12-05 WO PCT/JP2008/072201 patent/WO2009072629A1/ja not_active Ceased
- 2008-12-05 EP EP08856959.5A patent/EP2233154A4/en not_active Withdrawn
- 2008-12-05 TW TW097147593A patent/TWI438007B/zh not_active IP Right Cessation
- 2008-12-05 BR BRPI0821087-0A patent/BRPI0821087A2/pt not_active IP Right Cessation
- 2008-12-05 KR KR1020107014847A patent/KR101591672B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008332297A1 (en) | 2009-06-11 |
| WO2009072629A1 (ja) | 2009-06-11 |
| JP4341983B2 (ja) | 2009-10-14 |
| US20100316581A1 (en) | 2010-12-16 |
| AU2008332297B2 (en) | 2015-01-29 |
| TW200932282A (en) | 2009-08-01 |
| KR101591672B1 (ko) | 2016-02-04 |
| RU2010128073A (ru) | 2012-01-20 |
| EP2233154A1 (en) | 2010-09-29 |
| CN101918031A (zh) | 2010-12-15 |
| JP2009155326A (ja) | 2009-07-16 |
| TWI438007B (zh) | 2014-05-21 |
| EP2233154A4 (en) | 2016-01-06 |
| KR20100098677A (ko) | 2010-09-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0821087A2 (pt) | Preparação externa para a pele. | |
| EP2148765A4 (en) | RAZOR | |
| PL2134496T3 (pl) | Wkładka skrawająca | |
| BRPI0812264A2 (pt) | Vesícula, e, preparação externa para pele | |
| EP2211787A4 (en) | MITRAL SPACEUR | |
| HRP20150509T1 (xx) | Herbicidni pripravci | |
| CL2007002783S1 (es) | Inhalador multidosis. | |
| BRPI0812818A2 (pt) | Turbo-reator para aeronave | |
| BRPI0815670A2 (pt) | Inseticidas | |
| BRPI0814926A2 (pt) | Herbicidas | |
| BRPI0815651A2 (pt) | Herbicidas | |
| BR112012000434A2 (pt) | procedimento para a fabricação de piscinas naturais. | |
| BRPI0912134A2 (pt) | preparação externa para pele | |
| BRPI0808032A2 (pt) | Processos para preparar hidroxipivalinaldeído e para preparar neopentil glicol. | |
| BRPI0814736A2 (pt) | inalador. | |
| DK2125048T3 (da) | Præparat | |
| BRPI0817379A2 (pt) | aeronave | |
| PT2223114T (pt) | Calibrante para imunoensaios | |
| BRPI0818697A2 (pt) | Depilador | |
| DE602007005796D1 (de) | Schneidegerät | |
| EP2216078A4 (en) | BADMINTON | |
| BRPI0816208A2 (pt) | herbicidas | |
| DE602007009636D1 (de) | Sektionaltor | |
| DK2170751T3 (da) | Opvindingsindretning | |
| FR2916433B1 (fr) | Decoupe capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: dismissal - article 86 of industrial property law | ||
| B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |