BRPI0821565A2 - Ingrediente farmacêutico ativo sobre um suporte sólido, amorfo e com uma solubilidade aperfeiçoada - Google Patents

Ingrediente farmacêutico ativo sobre um suporte sólido, amorfo e com uma solubilidade aperfeiçoada

Info

Publication number
BRPI0821565A2
BRPI0821565A2 BRPI0821565-0A BRPI0821565A BRPI0821565A2 BR PI0821565 A2 BRPI0821565 A2 BR PI0821565A2 BR PI0821565 A BRPI0821565 A BR PI0821565A BR PI0821565 A2 BRPI0821565 A2 BR PI0821565A2
Authority
BR
Brazil
Prior art keywords
solid
active pharmaceutical
pharmaceutical ingredient
improved solubility
amorphous support
Prior art date
Application number
BRPI0821565-0A
Other languages
English (en)
Inventor
Rock Grahek
Aleksander Resman
Andrej Bastarda
Martin Crnugelj
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Publication of BRPI0821565A2 publication Critical patent/BRPI0821565A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0821565-0A 2007-12-21 2008-12-18 Ingrediente farmacêutico ativo sobre um suporte sólido, amorfo e com uma solubilidade aperfeiçoada BRPI0821565A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07150359A EP2072042A1 (en) 2007-12-21 2007-12-21 Active pharmaceutical ingredient on solid support, amorphous and with improved solubility
PCT/EP2008/067875 WO2009080698A1 (en) 2007-12-21 2008-12-18 Active pharmaceutical ingredient on a solid support, amorphous and with an improved solubility

Publications (1)

Publication Number Publication Date
BRPI0821565A2 true BRPI0821565A2 (pt) 2015-06-16

Family

ID=39400469

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821565-0A BRPI0821565A2 (pt) 2007-12-21 2008-12-18 Ingrediente farmacêutico ativo sobre um suporte sólido, amorfo e com uma solubilidade aperfeiçoada

Country Status (10)

Country Link
US (1) US20100305087A1 (pt)
EP (2) EP2072042A1 (pt)
JP (1) JP2011506561A (pt)
CN (1) CN101903015A (pt)
AU (1) AU2008340057A1 (pt)
BR (1) BRPI0821565A2 (pt)
CA (1) CA2710125A1 (pt)
EA (1) EA201070780A1 (pt)
MX (1) MX2010006896A (pt)
WO (1) WO2009080698A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2238979A1 (en) * 2009-04-06 2010-10-13 LEK Pharmaceuticals d.d. Active pharmaceutical ingredient adsorbed on solid support
CN102764264A (zh) * 2012-07-25 2012-11-07 杭州和泽医药科技有限公司 一种具高溶出度的塞来昔布固体组合物、制备方法及应用
ES2908958T3 (es) * 2013-02-01 2022-05-04 Grace W R & Co Gel de sílice porosa como portador para tecnologías líquidas
WO2016019252A1 (en) * 2014-08-01 2016-02-04 Johnson & Johnson Consumer Inc. Core compositions
CN104771761A (zh) * 2015-03-19 2015-07-15 深圳国源国药有限公司 一种创新药用辅料硅化微晶纤维素及其制备方法
DE102016218604A1 (de) 2016-09-27 2018-03-29 Constantin Adams Partikuläres Stoffgemisch, vorzugsweise zur Verwendung bei der Prophylaxe und/oder Behandlung einer Atemwegsstörung
CN114917353A (zh) * 2022-06-27 2022-08-19 瑞阳制药股份有限公司 硝唑尼特药物组合物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0129893B1 (en) 1983-06-28 1991-09-04 Takeda Chemical Industries, Ltd. Ground mixture
WO1996039126A2 (en) * 1995-06-06 1996-12-12 Warner-Lambert Company Ranitidine salts on magnesium trisilicate as an adsorbate
OA12625A (en) * 2001-06-22 2006-06-12 Pfizer Prod Inc Pharmaceutical compositions of adsorbates of amorphous drug.
BRPI0413277A (pt) * 2003-08-04 2006-10-10 Pfizer Prod Inc composições farmacêuticas de adsorvatos de medicamentos amorfos e materiais que formam microfases lipofìlicas
AU2004308419B2 (en) * 2003-12-24 2011-06-02 Victory Pharma, Inc. Enhanced absorption of modified release dosage forms
EP1905424A3 (en) * 2006-02-02 2008-04-30 Ranbaxy Laboratories Limited Process for the preparation of a pharmaceutical composition comprising stabilized statin particles
MX2008011418A (es) * 2006-03-06 2008-09-22 Teva Pharma Composiciones de ezetimibe.

Also Published As

Publication number Publication date
WO2009080698A1 (en) 2009-07-02
CA2710125A1 (en) 2009-07-02
AU2008340057A1 (en) 2009-07-02
US20100305087A1 (en) 2010-12-02
MX2010006896A (es) 2010-10-05
EA201070780A1 (ru) 2010-12-30
JP2011506561A (ja) 2011-03-03
EP2072042A1 (en) 2009-06-24
CN101903015A (zh) 2010-12-01
EP2234602A1 (en) 2010-10-06

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.