BRPI0822221A2 - Composições aquosas e estáveis de ciclosporina - Google Patents

Composições aquosas e estáveis de ciclosporina

Info

Publication number: BRPI0822221A2
Authority: BR; Brazil
Prior art keywords: aqueous; stable; cyclosporine compositions; cyclosporine; compositions
Prior art date: 2008-01-04

Application number

BRPI0822221-5A

Other languages

English (en)

Inventor

William Francis Stringer

Original Assignee

Alcon Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-01-04

Filing date

2008-11-17

Publication date

2015-06-23

2008-11-17 Application filed by Alcon Pharmaceuticals Ltd filed Critical Alcon Pharmaceuticals Ltd

2015-06-23 Publication of BRPI0822221A2 publication Critical patent/BRPI0822221A2/pt

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Ophthalmology & Optometry (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0822221-5A 2008-01-04 2008-11-17 Composições aquosas e estáveis de ciclosporina BRPI0822221A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1908808P	2008-01-04	2008-01-04
PCT/US2008/083789 WO2009088570A1 (en)	2008-01-04	2008-11-17	Stable aqueous cyclosporin compositions

Publications (1)

Publication Number	Publication Date
BRPI0822221A2 true BRPI0822221A2 (pt)	2015-06-23

Family

ID=40853358

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0822221-5A BRPI0822221A2 (pt)	2008-01-04	2008-11-17	Composições aquosas e estáveis de ciclosporina

Country Status (11)

Country	Link
US (1)	US20090286718A1 (pt)
EP (1)	EP2234629A4 (pt)
JP (1)	JP2011508776A (pt)
KR (1)	KR20100107462A (pt)
CN (1)	CN101990437A (pt)
AU (1)	AU2008346954A1 (pt)
BR (1)	BRPI0822221A2 (pt)
CA (1)	CA2710843A1 (pt)
MX (1)	MX2010007295A (pt)
RU (1)	RU2010132642A (pt)
WO (1)	WO2009088570A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8741930B2 (en) *	2008-10-24	2014-06-03	Bridge Pharma, Inc.	Treating xerophthalmia with norketotifen
WO2010059894A1 (en)	2008-11-21	2010-05-27	Bridge Pharma, Inc.	Ocular formulations of norketotifen
MY180581A (en) *	2011-05-27	2020-12-02	Allergan Inc	A crystalline form of cyclosporine a, methods of preparation, and methods for use thereof
US20130029919A1 (en) *	2011-07-26	2013-01-31	Allergan, Inc.	Two part formulation system for opthalmic delivery
DE102011108948A1 (de) *	2011-07-29	2013-01-31	Achim Göpferich	Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen
KR101510764B1 (ko) *	2011-10-10	2015-04-10	김용남	사이클로스포린 함유 안약 조성물 및 그 제조방법
AU2012339701B8 (en)	2011-11-15	2017-11-16	Allergan, Inc.	Autoclavable suspensions of cyclosporin A Form 2
CN104080442B (zh)	2011-11-15	2018-01-05	阿勒根公司	环孢菌素a形式2的悬浮液
FR2988297B1 (fr)	2012-03-22	2014-03-28	Thea Lab	Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
ES2948387T3 (es)	2012-08-24	2023-09-11	Sun Pharmaceutical Ind Ltd	Formulación oftálmica de ácidos grasos polioxílicos o lípidos polioxílicos y tratamiento de afecciones oculares
JP2017007995A (ja) *	2015-06-25	2017-01-12	ライオン株式会社	洗眼剤組成物及び洗眼方法
KR101587385B1 (ko) *	2015-07-29	2016-01-21	국제약품공업주식회사	사이클로스포린 함유 무자극성의 안약조성물 및 편리한 제조방법
DK3373976T3 (da)	2015-11-10	2024-04-02	Sun Pharmaceutical Ind Ltd	Topiske formuleringer og anvendelser deraf
PT3423076T (pt)	2016-02-29	2024-07-01	Sun Pharmaceutical Ind Ltd	Formulações tópicas contendo ciclosporina e respetivas utilizações
RU2620568C1 (ru) *	2016-04-12	2017-05-26	Государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный педиатрический медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО СПбГПМУ Минздрава России)	Препарат для лечения синдрома "сухого глаза"
ES2988617T3 (es)	2016-09-08	2024-11-21	Emergo Therapeutics Inc	Norketotifeno para el tratamiento de la hipercitocinemia y las infecciones virales
CA3040420A1 (en)	2016-10-18	2018-04-26	Emergo Therapeutics, Inc.	Mast cell stabilizers for treatment of chronic inflammatory conditions
US10702578B2 (en) *	2017-08-02	2020-07-07	Shilpa Medicare Limited	Ophthalmic compositions of cyclosporine
KR102152506B1 (ko) *	2018-11-08	2020-09-07	한국식품연구원	산소제거 기능성 마스터배치 및 이의 제조방법
CA3132923A1 (en) *	2019-03-08	2020-09-17	Emphascience, Inc.	Stable pharmaceutical formulations of peptide and protein drugs
US20210290527A1 (en) *	2020-03-23	2021-09-23	Eyegate Pharmaceuticals, Inc.	Compositions and Methods for Treatment of Ocular Conditions
EP4437434A4 (en) *	2022-01-21	2025-02-05	Elemental Cognition Inc.	Interactive research assistant
US20240180826A1 (en) *	2022-12-06	2024-06-06	Marc Selner	Opthalmic Compositions for Dry Eye Treatment and Methods of Manufacture of the Same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG45449A1 (en) *	1992-05-13	1998-01-16	Sandoz Ltd	Ophthalmic compositions
MX9701946A (es) *	1997-03-14	1998-04-30	Arturo Jimenez Bayardo	Solucion oftalmica transportadora.
JP3554514B2 (ja) *	1999-12-03	2004-08-18	松下電器産業株式会社	半導体装置及びその製造方法
US6984628B2 (en) *	2003-07-15	2006-01-10	Allergan, Inc.	Ophthalmic compositions comprising trefoil factor family peptides
US20050059583A1 (en) *	2003-09-15	2005-03-17	Allergan, Inc.	Methods of providing therapeutic effects using cyclosporin components
WO2006073786A2 (en) *	2004-12-30	2006-07-13	Bausch & Lomb Incorporated	Ophthalmic compositions comprising steroid and cyclosporine for dry eye therapy
US7501393B2 (en) *	2005-07-27	2009-03-10	Allergan, Inc.	Pharmaceutical compositions comprising cyclosporins
US20070087962A1 (en) *	2005-10-17	2007-04-19	Allergan, Inc.	Pharmaceutical compositions comprising cyclosporins

2008
- 2008-11-17 US US12/272,445 patent/US20090286718A1/en not_active Abandoned
- 2008-11-17 CN CN2008801279448A patent/CN101990437A/zh active Pending
- 2008-11-17 KR KR1020107014730A patent/KR20100107462A/ko not_active Withdrawn
- 2008-11-17 CA CA2710843A patent/CA2710843A1/en not_active Abandoned
- 2008-11-17 AU AU2008346954A patent/AU2008346954A1/en not_active Abandoned
- 2008-11-17 BR BRPI0822221-5A patent/BRPI0822221A2/pt not_active IP Right Cessation
- 2008-11-17 JP JP2010541459A patent/JP2011508776A/ja not_active Abandoned
- 2008-11-17 MX MX2010007295A patent/MX2010007295A/es not_active Application Discontinuation
- 2008-11-17 EP EP08869832A patent/EP2234629A4/en not_active Withdrawn
- 2008-11-17 WO PCT/US2008/083789 patent/WO2009088570A1/en not_active Ceased
- 2008-11-17 RU RU2010132642/15A patent/RU2010132642A/ru not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN101990437A (zh)	2011-03-23
JP2011508776A (ja)	2011-03-17
EP2234629A4 (en)	2011-05-25
KR20100107462A (ko)	2010-10-05
RU2010132642A (ru)	2012-02-10
WO2009088570A1 (en)	2009-07-16
CA2710843A1 (en)	2009-07-16
EP2234629A1 (en)	2010-10-06
US20090286718A1 (en)	2009-11-19
MX2010007295A (es)	2010-10-11
AU2008346954A1 (en)	2009-07-16

Legal Events

Date	Code	Title	Description
2015-08-25	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A E 6A ANUIDADES.
2016-05-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BRPI0822221A2 (pt)	2015-06-23	Composições aquosas e estáveis de ciclosporina
BRPI0922084A2 (pt)	2015-01-27	Composições e métodos compreendendo variantes de serina protease
PL2356462T3 (pl)	2017-07-31	Kompozycje anty-CXCR1 oraz sposoby
PL2424372T3 (pl)	2018-07-31	Kompozycje przeciwdrobnoustrojowe i powiązane sposoby zastosowania
BRPI0907155A2 (pt)	2015-07-07	Composições pesticidas
BRPI0918652A2 (pt)	2015-08-25	Composições farmacêuticas e métodos de libração relacionadas.
DK2634232T3 (da)	2022-06-07	Sammensætninger
DK2396339T3 (da)	2014-10-13	Pesticidsammensætninger
BRPI1014543A2 (pt)	2016-04-05	composições pesticidas
BRPI0912634A2 (pt)	2015-08-18	Composições pesticidas
BRPI0907231A2 (pt)	2019-09-24	pirrolpirimidinas e pirrolpiridinas
FR2933868B1 (fr)	2012-08-17	Compositions cosmetiques
BRPI0913086A2 (pt)	2015-08-04	Composições antimicrobianas e métodos de uso
BRPI0912213A2 (pt)	2015-10-06	preparação cosmética
EP2519104A4 (en)	2014-04-09	PESTICIDE COMPOSITION
BRPI0914781A2 (pt)	2015-08-04	Microbiocidas
FI20096058A0 (fi)	2009-10-13	Koostumuksia ja niihin liittyviä menetelmiä ja käyttöjä
BRPI1016117A2 (pt)	2016-04-12	derivados de isoxazol-isoxazol e isoxasol-isotiazol.
BR112012003258A2 (pt)	2015-09-01	Composição ativa de aroma
BRPI0813922A2 (pt)	2017-05-09	composições de inibição de influenza e métodos.
BRPI0816995A2 (pt)	2015-03-24	Composições de ciclosporina
BRPI0914063A2 (pt)	2015-11-03	composição de xampu concentrado
BRPI1009446A2 (pt)	2015-08-18	Composições compreendendo monatina e cálcio
BRPI0919048A2 (pt)	2015-08-18	Composições pesticidas
DK2396338T3 (da)	2014-06-30	Pesticidsammensætninger