BRPI0823234A2 - nanovesícula para liberação de um agente para uma membrana biológica e processo para direcionar um agente para uma membrana de uma célula ou um tecido. - Google Patents
nanovesícula para liberação de um agente para uma membrana biológica e processo para direcionar um agente para uma membrana de uma célula ou um tecido.Info
- Publication number
- BRPI0823234A2 BRPI0823234A2 BRPI0823234A BRPI0823234A BRPI0823234A2 BR PI0823234 A2 BRPI0823234 A2 BR PI0823234A2 BR PI0823234 A BRPI0823234 A BR PI0823234A BR PI0823234 A BRPI0823234 A BR PI0823234A BR PI0823234 A2 BRPI0823234 A2 BR PI0823234A2
- Authority
- BR
- Brazil
- Prior art keywords
- agent
- nanovesicle
- directing
- releasing
- tissue
- Prior art date
Links
- 210000000170 cell membrane Anatomy 0.000 title 1
- 239000012528 membrane Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2008/082805 WO2010053489A1 (en) | 2008-11-07 | 2008-11-07 | Fusogenic properties of saposin c and related proteins and peptides for application to transmembrane drug delivery systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0823234A2 true BRPI0823234A2 (pt) | 2019-09-24 |
Family
ID=42153126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0823234A BRPI0823234A2 (pt) | 2008-11-07 | 2008-11-07 | nanovesícula para liberação de um agente para uma membrana biológica e processo para direcionar um agente para uma membrana de uma célula ou um tecido. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120020878A1 (pt) |
| EP (1) | EP2365796A4 (pt) |
| JP (1) | JP2012508233A (pt) |
| CN (1) | CN102264349A (pt) |
| AU (1) | AU2008363813A1 (pt) |
| BR (1) | BRPI0823234A2 (pt) |
| CA (1) | CA2742831A1 (pt) |
| WO (1) | WO2010053489A1 (pt) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5253402B2 (ja) * | 2006-10-20 | 2013-07-31 | チルドレンズ ホスピタル メディカル センター | 自発的に形成する楕円体の単層リン脂質小胞 |
| US9205099B2 (en) | 2010-06-22 | 2015-12-08 | Dna Therapeutics | Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates |
| CN108926535B (zh) * | 2011-02-01 | 2020-12-29 | 常州长吉生物技术开发有限公司 | SapC-磷脂纳米囊泡冻干制剂、 其制备方法及用途 |
| EP2527440A1 (en) | 2011-05-27 | 2012-11-28 | Institut Curie | Cancer treatment by combining DNA molecules mimicking double strand breaks with hyperthermia |
| WO2013059617A1 (en) * | 2011-10-21 | 2013-04-25 | Ndsu Research Foundation | Liposome compositions and methods of use |
| US10138474B2 (en) * | 2012-08-17 | 2018-11-27 | Research Foundation Of The City University Of New York | Scavenger receptor uptake for fabry disease enzyme replacement therapy |
| EP2745834B1 (en) | 2012-12-18 | 2016-09-28 | Jens Frauenfeld | Salipro particles |
| LT3043814T (lt) | 2013-09-13 | 2021-02-25 | Salipro Biotech AB | Antigenas ir jo gamybos būdas |
| SG11201700557RA (en) * | 2014-07-24 | 2017-02-27 | Toppan Printing Co Ltd | Lipid membrane structure, lipid-membrane-structure-immobilization carrier, and method for fusing cells |
| US10570173B2 (en) * | 2015-01-22 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Protease-activated contrast agents for in vivo imaging |
| EP3235908A1 (en) | 2016-04-21 | 2017-10-25 | Ecole Normale Superieure De Lyon | Methods for selectively modulating the activity of distinct subtypes of cells |
| US10493172B2 (en) | 2016-06-02 | 2019-12-03 | California Institute Of Technology | Gas-filled structures and related compositions, methods and systems to image a target site |
| US11118210B2 (en) | 2016-07-28 | 2021-09-14 | California Institute Of Technology | Genetically engineered gas vesicle gene clusters, genetic circuits, vectors, prokaryotic cells, compositions, methods and systems for contrast-enhanced imaging |
| AU2018266111B2 (en) | 2017-05-08 | 2024-11-07 | Flagship Pioneering Innovations V, Inc. | Compositions for facilitating membrane fusion and uses thereof |
| US10682411B2 (en) * | 2018-03-23 | 2020-06-16 | Bexion Pharmaceuticals Inc. | Saposin C pharmaceutical compositions and methods of treating cancer |
| EP3820509A1 (en) | 2018-07-09 | 2021-05-19 | Flagship Pioneering Innovations V, Inc. | Fusosome compositions and uses thereof |
| SG11202105079QA (en) * | 2018-11-14 | 2021-06-29 | Flagship Pioneering Innovations V Inc | Fusosome compositions for cns delivery |
| US12496274B2 (en) | 2018-11-14 | 2025-12-16 | Flagship Pioneering Innovations V, Inc. | Compositions and methods for compartment-specific cargo delivery |
| US11786218B2 (en) | 2019-01-07 | 2023-10-17 | California Institute Of Technology | Burst ultrasound reconstruction with signal templates and related methods and systems |
| WO2020146379A1 (en) | 2019-01-07 | 2020-07-16 | California Institute Of Technology | Gas vesicle expression systems, gas vesicle constructs and related genetic circuits, vectors, mammalian cells, hosts, compositions, methods and systems |
| BR112021015312A2 (pt) * | 2019-02-04 | 2021-11-09 | Freeline Therapeutics Ltd | Polinucleotídeos, partícula viral e composição |
| KR20210124310A (ko) * | 2019-02-06 | 2021-10-14 | 벤테라, 인코포레이티드 | 국소 포스포이노시티드 3-키나제 억제제 |
| US11446523B2 (en) * | 2019-03-28 | 2022-09-20 | California Institute Of Technology | Compositions, methods and systems for gas vesicle based cavitation |
| US20230103407A1 (en) * | 2020-03-10 | 2023-04-06 | University Of Cincinnati | Materials and methods for the treatment of gaucher disease |
| US20230248838A1 (en) * | 2020-08-03 | 2023-08-10 | Silo Pharma, Inc. | Central nervous system delivery of nonsteroidal anti-inflammatory drugs |
| IL307544A (en) | 2021-04-08 | 2023-12-01 | Sana Biotechnology Inc | Cd8-specific antibody constructs and compositions thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6872406B2 (en) * | 2000-02-11 | 2005-03-29 | Children's Hospital Research Foundation | Fusogenic properties of saposin C and related proteins and polypeptides for application to transmembrane drug delivery systems |
| US7166691B2 (en) * | 2002-12-20 | 2007-01-23 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Saposin C and receptors as targets for treatment of benign and malignant disorders |
| ES2641272T3 (es) * | 2006-04-28 | 2017-11-08 | Children's Hospital Medical Center | Composiciones que comprenden proteínas o polipéptidos fusogénicos derivados de la prosaposina para aplicación en sistemas de suministro de fármacos transmembrana |
| JP5253402B2 (ja) * | 2006-10-20 | 2013-07-31 | チルドレンズ ホスピタル メディカル センター | 自発的に形成する楕円体の単層リン脂質小胞 |
| US20080206139A1 (en) * | 2006-11-03 | 2008-08-28 | The Penn State Research Foundation | Delivery system for diagnostic and therapeutic agents |
-
2008
- 2008-11-07 CN CN2008801324890A patent/CN102264349A/zh active Pending
- 2008-11-07 WO PCT/US2008/082805 patent/WO2010053489A1/en not_active Ceased
- 2008-11-07 JP JP2011535548A patent/JP2012508233A/ja active Pending
- 2008-11-07 AU AU2008363813A patent/AU2008363813A1/en not_active Abandoned
- 2008-11-07 CA CA2742831A patent/CA2742831A1/en not_active Abandoned
- 2008-11-07 US US13/127,630 patent/US20120020878A1/en not_active Abandoned
- 2008-11-07 EP EP20080878045 patent/EP2365796A4/en not_active Withdrawn
- 2008-11-07 BR BRPI0823234A patent/BRPI0823234A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012508233A (ja) | 2012-04-05 |
| AU2008363813A1 (en) | 2010-05-14 |
| EP2365796A4 (en) | 2015-04-29 |
| EP2365796A1 (en) | 2011-09-21 |
| WO2010053489A1 (en) | 2010-05-14 |
| CA2742831A1 (en) | 2010-05-14 |
| CN102264349A (zh) | 2011-11-30 |
| US20120020878A1 (en) | 2012-01-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |