BRPI0904955A2 - Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e métodos para tratar dor aguda e para fazer um depósito de drogas implantável. - Google Patents

Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e métodos para tratar dor aguda e para fazer um depósito de drogas implantável.

Info

Publication number
BRPI0904955A2
BRPI0904955A2 BRPI0904955-0A BRPI0904955A BRPI0904955A2 BR PI0904955 A2 BRPI0904955 A2 BR PI0904955A2 BR PI0904955 A BRPI0904955 A BR PI0904955A BR PI0904955 A2 BRPI0904955 A2 BR PI0904955A2
Authority
BR
Brazil
Prior art keywords
drug depot
implantable drug
pain
patient
treatment
Prior art date
Application number
BRPI0904955-0A
Other languages
English (en)
Inventor
John Myers Zanella
Vanja Margareta King
Christopher M Hobot
S Mark Cox
William F Mckay
Kathy L Remsen
Original Assignee
Warsaw Orthopedic Inc
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warsaw Orthopedic Inc, Medtronic Inc filed Critical Warsaw Orthopedic Inc
Publication of BRPI0904955A2 publication Critical patent/BRPI0904955A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BRPI0904955-0A 2008-04-18 2009-04-13 Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e métodos para tratar dor aguda e para fazer um depósito de drogas implantável. BRPI0904955A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/105,864 US8524267B2 (en) 2008-04-18 2008-04-18 Dexamethasone formulations in a biodegradable material
PCT/US2009/040295 WO2009129155A2 (en) 2008-04-18 2009-04-13 Dexamethasone formulations in a biodegradable material

Publications (1)

Publication Number Publication Date
BRPI0904955A2 true BRPI0904955A2 (pt) 2015-06-30

Family

ID=41199668

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0904955-0A BRPI0904955A2 (pt) 2008-04-18 2009-04-13 Depósito implantável de drogas para reduzir, prevenir ou tratar dor em um paciente em necessidade de tal tratamento e métodos para tratar dor aguda e para fazer um depósito de drogas implantável.

Country Status (7)

Country Link
US (3) US8524267B2 (pt)
EP (1) EP2187866A4 (pt)
JP (1) JP2011518164A (pt)
CN (1) CN101917968A (pt)
AU (1) AU2009236419A1 (pt)
BR (1) BRPI0904955A2 (pt)
WO (1) WO2009129155A2 (pt)

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US20090110637A1 (en) * 2007-10-26 2009-04-30 Warsaw Orthopedic, Inc. LMP and Regulation of Tissue Growth
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
US20100239632A1 (en) 2009-03-23 2010-09-23 Warsaw Orthopedic, Inc. Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue
US20110027331A1 (en) * 2009-07-29 2011-02-03 Warsaw Orthopedic, Inc. An implantable drug depot having a reversible phase transition material for treatment of pain and/or inflammation
US8916186B2 (en) * 2009-10-23 2014-12-23 DePuy Synthes Products, LLC Methods and devices for correcting spinal deformity with pharmaceutical-eluting pedicle screws
WO2012122436A2 (en) * 2011-03-08 2012-09-13 The Regents Of The University Of California Molecular zipper tweezers and spring devices
RU2703303C2 (ru) * 2013-05-24 2019-10-16 Данмаркс Текниске Университет Состав геля для лучевой терапии под визуальным контролем
CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
DE102014005782A1 (de) * 2014-04-23 2015-10-29 Martin-Luther-Universität Halle-Wittenberg lnjizierbare und implantierbare Trägersysteme auf Basis von modifizierten Poly(dikarbonsäure-multiol estern) zur kontrollierten Wirkstofffreisetzung
US20150342964A1 (en) * 2014-05-30 2015-12-03 Warsaw Orthopedic, Inc. Dexamethasone polymer implant for pain
CA2955229C (en) 2014-07-17 2020-03-10 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
CA3002099A1 (en) 2015-12-30 2017-07-06 Dexcom, Inc. Diffusion resistance layer for analyte sensors
WO2018005541A1 (en) * 2016-06-27 2018-01-04 University Of Iowa Research Foundation Magnetically-activated coating for treating biofilms, and associated systems and methods
PL3548091T3 (pl) 2016-11-29 2022-03-28 Oculis SA Otrzymywanie stałych kompleksów cyklodekstryny do dostarczenia czynnego składnika farmaceutycznego do oczu
WO2019071245A1 (en) 2017-10-06 2019-04-11 Foundry Therapeutics, Inc. IMPLANTABLE DEPOSITS FOR REGULATED RELEASE OF ANALGESICS TO TREAT POSTHOPERATIVE PAIN ASSOCIATED WITH ORTHOPEDIC SURGERY, AND RELATED DEVICES, SYSTEMS, AND METHODS
CN116650732A (zh) 2018-01-08 2023-08-29 铸造疗法股份有限公司 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法
US12458589B2 (en) 2018-05-12 2025-11-04 Foundry Therapeutics, Inc. Implantable polymer depots for the controlled release of therapeutic agents
WO2020047013A1 (en) 2018-08-28 2020-03-05 Foundry Therapeutics, Inc. Polymer implants
WO2020168106A1 (en) 2019-02-13 2020-08-20 Notable Labs, Inc. Combinations of agonists of protein kinase c with steroids or retinoic acids for the treatment of cancer
DK3993807T3 (da) 2019-07-01 2026-01-19 Oculis Operations Sarl Fremgangsmåde til stabilisering af ph-værden i en vandig sammensætning, der indeholder et lægemiddel
US12383246B2 (en) 2020-10-12 2025-08-12 Abbott Cardiovascular Systems, Inc. Vessel closure device with improved safety and tract hemostasis
GB202019594D0 (en) * 2020-12-11 2021-01-27 Univ London Queen Mary Sustained release formulations of crystalline drugs

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Also Published As

Publication number Publication date
US8524267B2 (en) 2013-09-03
US20150065474A1 (en) 2015-03-05
EP2187866A2 (en) 2010-05-26
WO2009129155A3 (en) 2010-01-07
AU2009236419A1 (en) 2009-10-22
US9700567B2 (en) 2017-07-11
WO2009129155A2 (en) 2009-10-22
JP2011518164A (ja) 2011-06-23
EP2187866A4 (en) 2010-09-15
US20090263455A1 (en) 2009-10-22
US20130261095A1 (en) 2013-10-03
CN101917968A (zh) 2010-12-15
US8877226B2 (en) 2014-11-04

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