BRPI0904957A2 - Depósito de droga implantável útil para reduzir, prevenir ou tratando dor pós-operatória em um paciente e métodos de tratar ou prevenir dor pós-operatória em um paciente e de produzir um depósito de droga implantável. - Google Patents
Depósito de droga implantável útil para reduzir, prevenir ou tratando dor pós-operatória em um paciente e métodos de tratar ou prevenir dor pós-operatória em um paciente e de produzir um depósito de droga implantável.Info
- Publication number
- BRPI0904957A2 BRPI0904957A2 BRPI0904957-6A BRPI0904957A BRPI0904957A2 BR PI0904957 A2 BRPI0904957 A2 BR PI0904957A2 BR PI0904957 A BRPI0904957 A BR PI0904957A BR PI0904957 A2 BRPI0904957 A2 BR PI0904957A2
- Authority
- BR
- Brazil
- Prior art keywords
- patient
- treating
- preventing
- postoperative pain
- implantable drug
- Prior art date
Links
- 208000004550 Postoperative Pain Diseases 0.000 title 2
- 239000003814 drug Substances 0.000 title 2
- 229940079593 drug Drugs 0.000 title 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4634308P | 2008-04-18 | 2008-04-18 | |
| US12/420,177 US8846068B2 (en) | 2008-04-18 | 2009-04-08 | Methods and compositions for treating post-operative pain comprising a local anesthetic |
| PCT/US2009/041039 WO2009129509A2 (en) | 2008-04-18 | 2009-04-17 | Methods and compositions for treating post-operative pain comprising a local anesthetic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0904957A2 true BRPI0904957A2 (pt) | 2015-06-30 |
Family
ID=40792651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0904957-6A BRPI0904957A2 (pt) | 2008-04-18 | 2009-04-17 | Depósito de droga implantável útil para reduzir, prevenir ou tratando dor pós-operatória em um paciente e métodos de tratar ou prevenir dor pós-operatória em um paciente e de produzir um depósito de droga implantável. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8846068B2 (pt) |
| EP (1) | EP2229171A4 (pt) |
| JP (1) | JP2011518187A (pt) |
| CN (1) | CN101842099A (pt) |
| AU (1) | AU2009236089A1 (pt) |
| BR (1) | BRPI0904957A2 (pt) |
| CA (1) | CA2700736A1 (pt) |
| WO (1) | WO2009129509A2 (pt) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090110637A1 (en) * | 2007-10-26 | 2009-04-30 | Warsaw Orthopedic, Inc. | LMP and Regulation of Tissue Growth |
| JP2011503213A (ja) * | 2007-11-19 | 2011-01-27 | カプスレイテッド システムズ インコーポレイテッド | マイクロ粒子を使用する局所麻酔薬の持続放出および手術適用方法 |
| USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
| US8846068B2 (en) * | 2008-04-18 | 2014-09-30 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising a local anesthetic |
| US8822546B2 (en) * | 2008-12-01 | 2014-09-02 | Medtronic, Inc. | Flowable pharmaceutical depot |
| US20100239632A1 (en) | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
| DK2509609T3 (da) | 2009-12-08 | 2014-11-10 | Univ Vanderbilt | Forbedrede fremgangsmåder og sammensætninger for venehøst og autotransplantation |
| US20120009240A1 (en) * | 2010-07-08 | 2012-01-12 | Joshua Stopek | Films for Delivery of a Therapeutic Agent |
| AU2013257727B2 (en) * | 2012-05-10 | 2016-04-28 | Cellixbio Private Limited | Compositions and methods for the treatment of local pain |
| KR102189442B1 (ko) * | 2012-06-27 | 2020-12-11 | 메딘셀 에스.에이. | 소수성 조성물용 생분해성 약물 전달 |
| US9592227B2 (en) | 2013-03-15 | 2017-03-14 | Heron Therapeutics, Inc. | Compositions of a polyorthoester and an aprotic solvent |
| CN110575445B (zh) | 2013-03-21 | 2023-08-18 | 优普顺药物公司美国分部 | 可注射的持续释放组合物及其用于治疗关节炎症及相关疼痛的方法 |
| CN103933041B (zh) * | 2014-04-21 | 2016-03-16 | 青岛市中心医院 | 一种包含布比卡因的局部麻醉组合物及其应用 |
| WO2016044799A1 (en) * | 2014-09-19 | 2016-03-24 | Eupraxia Pharmaceuticals Inc. | Injectable microparticles for hyper-localized release of therapeutic agents |
| US20160143720A1 (en) * | 2014-11-26 | 2016-05-26 | Cormatrix Cardiovascular, Inc. | Mesh Fiber Members and Methods for Forming and Using Same for Treating Damaged Biological Tissue |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| AU2016343952A1 (en) | 2015-10-27 | 2018-05-10 | Eupraxia Pharmaceuticals Inc. | Sustained release formulations of local anesthetics |
| AU2016355236C1 (en) | 2015-11-16 | 2022-09-22 | Medincell | A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue |
| WO2017139487A1 (en) * | 2016-02-09 | 2017-08-17 | Northwind Medical, Inc. | Methods, agents, and devices for local neuromodulation of autonomic nerves |
| WO2017193066A1 (en) * | 2016-05-05 | 2017-11-09 | Liquidia Technologies, Inc. | Precision controlled load and release particles for post-operative pain |
| US11992482B2 (en) * | 2016-12-21 | 2024-05-28 | Rilento Pharma, Llc | Malleable controlled release local anesthetic with hemostatic composition |
| CN107789628B (zh) * | 2016-12-29 | 2021-07-23 | 天津键凯科技有限公司 | 一种聚乙二醇和局部麻醉药的结合物在非麻醉镇痛中的应用 |
| EP3615724B1 (en) | 2017-04-28 | 2024-02-28 | 3M Innovative Properties Company | Large denier nonwoven fiber webs |
| WO2018227293A1 (en) | 2017-06-13 | 2018-12-20 | The University Of British Columbia | Polymeric paste compositions for drug delivery |
| EP3691618A1 (en) | 2017-10-06 | 2020-08-12 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| CN116650732A (zh) | 2018-01-08 | 2023-08-29 | 铸造疗法股份有限公司 | 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法 |
| IT201800001890A1 (it) * | 2018-01-25 | 2019-07-25 | Fidia Farm Spa | Composizioni farmaceutiche per il trattamento del dolore postoperatorio |
| US10646252B2 (en) | 2018-03-08 | 2020-05-12 | Modern Surgical Solutions, Llc | Medication sleeve for a trocar assembly |
| US12458589B2 (en) | 2018-05-12 | 2025-11-04 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| EP3843710A1 (en) | 2018-08-28 | 2021-07-07 | Foundry Therapeutics, Inc. | Polymer implants |
| AU2019328276B2 (en) | 2018-08-31 | 2025-07-03 | Rilento Pharma, Llc | Pharmaceutical formulation and system and method for delivery |
| CN109316470A (zh) * | 2018-11-05 | 2019-02-12 | 中国医学科学院基础医学研究所 | 一种含有布比卡因的药物组合物及其制备方法和用途 |
| EP3897452B1 (en) * | 2018-12-21 | 2024-07-03 | Tepha, Inc. | Resorbable nonwoven pouches for medical device implants |
| US11806069B2 (en) | 2019-01-25 | 2023-11-07 | Warsaw Orthopedics, IN | Devices and methods for the diagnosis and treatment of discogenic back pain |
| WO2020232539A1 (en) | 2019-05-17 | 2020-11-26 | The Governing Council Of The University Of Toronto | Sustained release local anesthetic hydrogel composition |
| MX2023001089A (es) * | 2020-07-25 | 2023-04-27 | Pharmafina Ilac Satis Ve Pazarlama Anonim Sirketi | Combinacion de medicamentos en una forma farmaceutica parenteral para anestesia de larga duracion. |
| CN116669717A (zh) * | 2020-08-17 | 2023-08-29 | 美国人福制药公司 | 长效原位成型/胶凝组合物 |
| US12383246B2 (en) | 2020-10-12 | 2025-08-12 | Abbott Cardiovascular Systems, Inc. | Vessel closure device with improved safety and tract hemostasis |
| WO2023073574A1 (en) * | 2021-10-28 | 2023-05-04 | Cellix Bio Private Limited | Process for the preparation of piperidine carboxamides salt forms and thereof |
| CN119235853B (zh) * | 2024-11-21 | 2026-02-06 | 北京博恩特药业有限公司 | 一种布比卡因微球及其制备方法和应用 |
Family Cites Families (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4624255A (en) | 1982-02-18 | 1986-11-25 | Schenck Robert R | Apparatus for anastomosing living vessels |
| US4863457A (en) | 1986-11-24 | 1989-09-05 | Lee David A | Drug delivery device |
| US5700485A (en) * | 1992-09-10 | 1997-12-23 | Children's Medical Center Corporation | Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid |
| US5868789A (en) | 1997-02-03 | 1999-02-09 | Huebner; Randall J. | Removable suture anchor apparatus |
| US5522844A (en) | 1993-06-22 | 1996-06-04 | Johnson; Lanny L. | Suture anchor, suture anchor installation device and method for attaching a suture to a bone |
| US5626838A (en) | 1995-03-13 | 1997-05-06 | The Procter & Gamble Company | Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx |
| US5942241A (en) * | 1995-06-09 | 1999-08-24 | Euro-Celtique, S.A. | Formulations and methods for providing prolonged local anesthesia |
| US5759583A (en) | 1995-08-30 | 1998-06-02 | Syntex (U.S.A.) Inc. | Sustained release poly (lactic/glycolic) matrices |
| AU733867B2 (en) | 1996-06-24 | 2001-05-31 | Euro-Celtique S.A. | Methods for providing safe local anesthesia |
| ATE318580T1 (de) | 1996-12-20 | 2006-03-15 | Alza Corp | Gelzusammensetzungen und verfahren |
| US6294170B1 (en) | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| AU7389098A (en) | 1997-05-16 | 1998-12-08 | Brigham And Women's Hospital | Local anesthetic formulations |
| IL129951A0 (en) | 1997-07-02 | 2000-02-29 | Euro Celtique Sa | Prolonged anesthesia in joints and body spaces |
| US5972384A (en) * | 1997-10-01 | 1999-10-26 | University Of Maryland, Baltimore | Use of biologically active glass as a drug delivery system |
| TW577758B (en) | 1997-10-27 | 2004-03-01 | Ssp Co Ltd | Intra-articular preparation for the treatment of arthropathy |
| US6069129A (en) | 1998-03-13 | 2000-05-30 | Mrs, Llc | Elastin derived composition and method of using same |
| EP1077653B1 (en) | 1998-05-12 | 2004-03-31 | Boston Scientific Limited | Manual bone anchor placement devices |
| US6451335B1 (en) * | 1998-07-02 | 2002-09-17 | Euro-Celtique S.A. | Formulations and methods for providing prolonged local anesthesia |
| US6179862B1 (en) | 1998-08-14 | 2001-01-30 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
| US6632457B1 (en) | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
| US6927044B2 (en) | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
| US6565874B1 (en) | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| US6436099B1 (en) | 1999-04-23 | 2002-08-20 | Sdgi Holdings, Inc. | Adjustable spinal tether |
| US6287588B1 (en) | 1999-04-29 | 2001-09-11 | Macromed, Inc. | Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof |
| US7220281B2 (en) | 1999-08-18 | 2007-05-22 | Intrinsic Therapeutics, Inc. | Implant for reinforcing and annulus fibrosis |
| US7951201B2 (en) | 1999-10-20 | 2011-05-31 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
| US6461631B1 (en) | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| DK1244388T3 (da) | 1999-12-06 | 2007-05-14 | Warsaw Orthopedic Inc | Indretning til behandling af mellemhvirvelskiver |
| US6899716B2 (en) | 2000-02-16 | 2005-05-31 | Trans1, Inc. | Method and apparatus for spinal augmentation |
| US6589549B2 (en) | 2000-04-27 | 2003-07-08 | Macromed, Incorporated | Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles |
| DE60137542D1 (de) | 2001-01-03 | 2009-03-12 | Bausch & Lomb | Wirkstoffabgabevorrichtungen mit verzögerter freisetzung mehrere stoffe enthaltend |
| US20030152637A1 (en) | 2001-01-25 | 2003-08-14 | Mark Chasin | Local anesthetic, and method of use |
| US7229441B2 (en) | 2001-02-28 | 2007-06-12 | Warsaw Orthopedic, Inc. | Flexible systems for spinal stabilization and fixation |
| US7235043B2 (en) | 2001-03-09 | 2007-06-26 | Boston Scientific Scimed Inc. | System for implanting an implant and method thereof |
| IL142933A0 (en) | 2001-05-03 | 2002-04-21 | Dentis Technology Ltd | Polymeric dental implant and method for use thereof |
| US6913760B2 (en) * | 2001-08-06 | 2005-07-05 | New England Medical Hospitals, Inc. | Drug delivery composition |
| MXPA01011542A (es) | 2001-11-13 | 2003-05-22 | Alcon Inc | Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel. |
| US6974462B2 (en) | 2001-12-19 | 2005-12-13 | Boston Scientific Scimed, Inc. | Surgical anchor implantation device |
| US8133501B2 (en) | 2002-02-08 | 2012-03-13 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled drug delivery |
| TWI353854B (en) * | 2002-06-25 | 2011-12-11 | Alza Corp | Short duration depot formulations |
| US20040109893A1 (en) | 2002-06-25 | 2004-06-10 | Guohua Chen | Sustained release dosage forms of anesthetics for pain management |
| US20040001889A1 (en) * | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| EP1531757B1 (en) | 2002-07-19 | 2016-09-07 | Omeros Corporation | Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from |
| US7368126B2 (en) * | 2002-11-06 | 2008-05-06 | Guohua Chen | Controlled release depot formulations |
| US20040166088A1 (en) | 2003-01-15 | 2004-08-26 | Shalaby Shalaby W. | Polymeric precursors of non-absorbable, in situ-forming hydrogels and applications thereof |
| US9445901B2 (en) * | 2003-03-12 | 2016-09-20 | Deger C. Tunc | Prosthesis with sustained release analgesic |
| US7144412B2 (en) | 2003-06-25 | 2006-12-05 | Wolf Medical Enterprises, Inc. | Gold suture and method of use in wound closure |
| WO2005046746A2 (en) | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| US20050175709A1 (en) | 2003-12-11 | 2005-08-11 | Baty Ace M.Iii | Therapeutic microparticles |
| JP2007519756A (ja) | 2004-01-30 | 2007-07-19 | アンジオテック インターナショナル アーゲー | 拘縮を治療するための組成物および方法 |
| US7361168B2 (en) | 2004-04-21 | 2008-04-22 | Acclarent, Inc. | Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders |
| US7410480B2 (en) | 2004-04-21 | 2008-08-12 | Acclarent, Inc. | Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders |
| US20080124400A1 (en) * | 2004-06-24 | 2008-05-29 | Angiotech International Ag | Microparticles With High Loadings Of A Bioactive Agent |
| US8512730B2 (en) | 2004-07-12 | 2013-08-20 | Isto Technologies, Inc. | Methods of tissue repair and compositions therefor |
| US20060074422A1 (en) | 2004-09-27 | 2006-04-06 | Story Brooks J | Suture anchor and void filler combination |
| CN101119713A (zh) | 2004-11-24 | 2008-02-06 | 阿尔高克斯制药公司 | 类辣椒素凝胶制剂及其用途 |
| US7611494B2 (en) | 2005-02-08 | 2009-11-03 | Confluent Surgical, Inc. | Spray for fluent materials |
| EP1881821B1 (en) | 2005-05-20 | 2016-11-09 | Omeros Corporation | Compositions comprising ketoprofen and calcium channel antagonist for use in urological procedures |
| US7610100B2 (en) | 2005-12-30 | 2009-10-27 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating osteoarthritis |
| US7741273B2 (en) | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
| US20070253994A1 (en) | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Intraspinal Drug Delivery Methods and Devices To Alleviate Chronic Pelvic Pain |
| US20070264339A1 (en) * | 2006-05-12 | 2007-11-15 | Ap Pharma, Inc. | Base-stabilized polyorthoester formulations |
| US20080091207A1 (en) | 2006-10-13 | 2008-04-17 | Csaba Truckai | Bone treatment systems and methods |
| US9248219B2 (en) * | 2007-09-14 | 2016-02-02 | Boston Scientific Scimed, Inc. | Medical devices having bioerodable layers for the release of therapeutic agents |
| US8846068B2 (en) * | 2008-04-18 | 2014-09-30 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising a local anesthetic |
| US9132085B2 (en) * | 2008-04-18 | 2015-09-15 | Warsaw Orthopedic, Inc. | Compositions and methods for treating post-operative pain using clonidine and bupivacaine |
| US8629172B2 (en) * | 2008-04-18 | 2014-01-14 | Warsaw Orthopedic, Inc. | Methods and compositions for treating post-operative pain comprising clonidine |
-
2009
- 2009-04-08 US US12/420,177 patent/US8846068B2/en active Active
- 2009-04-17 WO PCT/US2009/041039 patent/WO2009129509A2/en not_active Ceased
- 2009-04-17 BR BRPI0904957-6A patent/BRPI0904957A2/pt not_active IP Right Cessation
- 2009-04-17 JP JP2011505246A patent/JP2011518187A/ja active Pending
- 2009-04-17 AU AU2009236089A patent/AU2009236089A1/en not_active Abandoned
- 2009-04-17 CA CA2700736A patent/CA2700736A1/en not_active Abandoned
- 2009-04-17 CN CN200980100909A patent/CN101842099A/zh active Pending
- 2009-04-17 EP EP09733201A patent/EP2229171A4/en not_active Ceased
-
2014
- 2014-09-29 US US14/499,469 patent/US9549920B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011518187A (ja) | 2011-06-23 |
| EP2229171A4 (en) | 2011-04-27 |
| US9549920B2 (en) | 2017-01-24 |
| AU2009236089A1 (en) | 2009-10-22 |
| US20150018390A1 (en) | 2015-01-15 |
| CN101842099A (zh) | 2010-09-22 |
| WO2009129509A4 (en) | 2010-04-08 |
| WO2009129509A2 (en) | 2009-10-22 |
| US20090264472A1 (en) | 2009-10-22 |
| US8846068B2 (en) | 2014-09-30 |
| EP2229171A2 (en) | 2010-09-22 |
| CA2700736A1 (en) | 2009-10-22 |
| WO2009129509A3 (en) | 2010-02-18 |
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