BRPI0906090A2 - substrato para análise de uma enzima, molécula e método para detectar atividade enzimática . - Google Patents
substrato para análise de uma enzima, molécula e método para detectar atividade enzimática .Info
- Publication number
- BRPI0906090A2 BRPI0906090A2 BRPI0906090A BRPI0906090A BRPI0906090A2 BR PI0906090 A2 BRPI0906090 A2 BR PI0906090A2 BR PI0906090 A BRPI0906090 A BR PI0906090A BR PI0906090 A BRPI0906090 A BR PI0906090A BR PI0906090 A2 BRPI0906090 A2 BR PI0906090A2
- Authority
- BR
- Brazil
- Prior art keywords
- enzyme
- molecule
- analysis
- substrate
- enzymatic activity
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
- 239000000758 substrate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3621108P | 2008-03-13 | 2008-03-13 | |
| PCT/US2009/037087 WO2009114763A2 (en) | 2008-03-13 | 2009-03-13 | Enzymatic substrates for multiple detection systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0906090A2 true BRPI0906090A2 (pt) | 2016-05-03 |
Family
ID=41065853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0906090A BRPI0906090A2 (pt) | 2008-03-13 | 2009-03-13 | substrato para análise de uma enzima, molécula e método para detectar atividade enzimática . |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8173784B2 (pt) |
| EP (2) | EP2706121A1 (pt) |
| JP (1) | JP2011514809A (pt) |
| CN (1) | CN102014929A (pt) |
| AU (1) | AU2009223222A1 (pt) |
| BR (1) | BRPI0906090A2 (pt) |
| CA (1) | CA2718276A1 (pt) |
| IL (1) | IL208521A0 (pt) |
| WO (1) | WO2009114763A2 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201017875D0 (en) * | 2010-10-22 | 2010-12-01 | Johnson Matthey Plc | Method of identifying a material |
| JP6466907B2 (ja) | 2013-03-15 | 2019-02-06 | パーキンエルマー・ヘルス・サイエンシーズ・インコーポレイテッドＰｅｒｋｉｎｅｌｍｅｒ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． | ライソゾーム病の検査に関する化合物および方法 |
| JP6624482B2 (ja) | 2014-07-29 | 2019-12-25 | 俊 保坂 | 超小型加速器および超小型質量分析装置 |
| US9575064B2 (en) | 2014-09-02 | 2017-02-21 | Perkinelmer Health Sciences, Inc. | Methods relating to testing for lysosomal storage disorders |
| MY194096A (en) | 2016-04-28 | 2022-11-11 | Spark Therapeutics Inc | Relative potency assay for viral vector encoding isomerhydrolases |
| WO2019056251A1 (zh) * | 2017-09-21 | 2019-03-28 | 大连理工大学 | 一组用于氨基/酚羟基标记的同位素标记试剂及其合成方法 |
| CN111269280B (zh) * | 2020-03-27 | 2021-07-13 | 江苏豪思睦可生物科技有限公司 | 用于检测溶酶体贮积症相关酶的化合物、对应内标和试剂盒 |
| US11591544B2 (en) | 2020-11-25 | 2023-02-28 | Akagera Medicines, Inc. | Ionizable cationic lipids |
| KR20250031230A (ko) | 2022-05-25 | 2025-03-06 | 아카제라 메디신즈, 인크. | 핵산 전달을 위한 지질 나노입자 및 이의 사용 방법 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2931833A (en) * | 1954-12-29 | 1960-04-05 | Armour & Co | Benzyldialkyl-2-(1-hydroxy-alkyl) alkyl ammonium chloride compounds |
| US3636114A (en) * | 1968-07-16 | 1972-01-18 | Union Carbide Corp | Novel quaternary ammonium compounds and method for preparation thereof |
| IT1116037B (it) * | 1979-04-23 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico |
| US4968785A (en) * | 1988-05-17 | 1990-11-06 | Henkel Kommanditgesellschaft Auf Aktien | Substituted glycoside compositions |
| JPH0243560A (ja) * | 1988-08-04 | 1990-02-14 | Canon Inc | 電子写真感光体 |
| US5138043A (en) * | 1989-12-07 | 1992-08-11 | Union Carbide Chemicals & Plastics Technology Corporation | Alkoxylated alkyl glucoside ether quaternaries useful in personal care |
| IT1261984B (it) * | 1993-06-22 | 1996-06-11 | Avantgarde Spa | Uso di esteri della l-carnitina o di acil l- carnitine con idrossiacidi per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee. |
| CA2165982A1 (en) * | 1993-07-23 | 1995-02-02 | Fuqiang Ruan | N,n,n-trimethylsphingosine derivatives |
| US5627171A (en) * | 1994-04-11 | 1997-05-06 | Oncomembrane, Inc. | Sphingosine-1-phosphate/trimethylsphingosine composition |
| AU7398996A (en) | 1995-10-11 | 1997-04-30 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| FR2767134B1 (fr) * | 1997-08-08 | 1999-09-24 | Ceca Sa | N-(dialkylamino)alkyl glycosylamines et derives, procedes de preparation,composition les contenant et utilisations, notamment dans le domaine de la cosmetique. |
| ATE253126T1 (de) * | 1998-08-25 | 2003-11-15 | Univ Washington | Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen |
| IT1306129B1 (it) * | 1999-04-13 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti |
| US6649414B1 (en) | 1999-08-17 | 2003-11-18 | Luminex Corporation | Microparticles with multiple fluorescent signals and methods of using same |
| US20020042536A1 (en) | 1999-10-08 | 2002-04-11 | Prasad S. Raje | Preparation of amino-protected lysine derivatives |
| JP2003530553A (ja) | 2000-04-10 | 2003-10-14 | エムシーダブリユー リサーチ フオンデーシヨン インコーポレーテツド | ２０−ｈｅｔｅおよびアラキドン酸の他のｐ−４５０代謝産物の蛍光ｈｐｌｃアッセイ |
| WO2004072238A2 (en) | 2003-02-05 | 2004-08-26 | Amersham Biosciences Corp | Terminal-phosphate-labeled nucleotides with new linkers |
| EP1740954B1 (en) * | 2004-04-07 | 2015-08-19 | Genentech, Inc. | Mass spectrometry of antibody conjugates |
| WO2007013601A1 (ja) * | 2005-07-28 | 2007-02-01 | Shinichiro Isobe | 生体分子用標識色素及び標識キット並びに生体分子の検出方法 |
| JP4364197B2 (ja) | 2005-12-27 | 2009-11-11 | 日本リライアンス株式会社 | 交流電源装置およびその装置におけるアーク抑制方法 |
| CN101426926A (zh) * | 2006-03-13 | 2009-05-06 | 珀金埃尔默Las公司 | 用于质谱法检测的底物和内标 |
| US8268865B2 (en) * | 2007-05-11 | 2012-09-18 | Rempex Pharmaceuticals, Inc. | Quaternary alkyl ammonium bacterial efflux pump inhibitors and therapeutic uses thereof |
-
2009
- 2009-03-13 WO PCT/US2009/037087 patent/WO2009114763A2/en not_active Ceased
- 2009-03-13 EP EP13184562.0A patent/EP2706121A1/en not_active Withdrawn
- 2009-03-13 BR BRPI0906090A patent/BRPI0906090A2/pt not_active IP Right Cessation
- 2009-03-13 CA CA2718276A patent/CA2718276A1/en not_active Abandoned
- 2009-03-13 AU AU2009223222A patent/AU2009223222A1/en not_active Abandoned
- 2009-03-13 CN CN2009801167273A patent/CN102014929A/zh active Pending
- 2009-03-13 US US12/403,790 patent/US8173784B2/en active Active
- 2009-03-13 JP JP2010550887A patent/JP2011514809A/ja active Pending
- 2009-03-13 EP EP09720998A patent/EP2265645A4/en not_active Withdrawn
-
2010
- 2010-10-06 IL IL208521A patent/IL208521A0/en unknown
-
2012
- 2012-04-03 US US13/438,029 patent/US8791246B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2265645A4 (en) | 2011-03-23 |
| IL208521A0 (en) | 2011-07-31 |
| CA2718276A1 (en) | 2009-09-17 |
| US20120190043A1 (en) | 2012-07-26 |
| US8173784B2 (en) | 2012-05-08 |
| WO2009114763A3 (en) | 2009-11-19 |
| EP2265645A2 (en) | 2010-12-29 |
| US20090253117A1 (en) | 2009-10-08 |
| EP2706121A1 (en) | 2014-03-12 |
| JP2011514809A (ja) | 2011-05-12 |
| CN102014929A (zh) | 2011-04-13 |
| WO2009114763A2 (en) | 2009-09-17 |
| AU2009223222A1 (en) | 2009-09-17 |
| US8791246B2 (en) | 2014-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |