BRPI0905853A2 - Meios de fermentação e processos destes. - Google Patents

Meios de fermentação e processos destes.

Info

Publication number
BRPI0905853A2
BRPI0905853A2 BRPI0905853-2A BRPI0905853A BRPI0905853A2 BR PI0905853 A2 BRPI0905853 A2 BR PI0905853A2 BR PI0905853 A BRPI0905853 A BR PI0905853A BR PI0905853 A2 BRPI0905853 A2 BR PI0905853A2
Authority
BR
Brazil
Prior art keywords
processes
fermentation media
fermentation
media
Prior art date
Application number
BRPI0905853-2A
Other languages
English (en)
Inventor
Tiwari Sanjay
Patale
Mukesh
Babuappa
Garg
Saurabh
Mayank
Kumar
Joshi Sulekha
Kumar Bimal
Goel Anuj
Chittnalli
Ramegowda
Naveen
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Publication of BRPI0905853A2 publication Critical patent/BRPI0905853A2/pt
Publication of BRPI0905853A8 publication Critical patent/BRPI0905853A8/pt
Publication of BRPI0905853B1 publication Critical patent/BRPI0905853B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18Carboxylic ester hydrolases (3.1.1)
    • C12N9/20Triglyceride splitting, e.g. by means of lipase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI0905853-2A 2008-02-06 2009-02-05 Processo para a produção de proteínas recombinantes, melhorando a incorporação de fosfato. BRPI0905853B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN00310/CHE/2008 2008-02-06
IN310CH2008 2008-02-06
IN00086/CHE/2009 2009-01-12
IN86CH2009 2009-01-12
PCT/IN2009/000078 WO2009113099A2 (en) 2008-02-06 2009-02-05 Fermentation medias and processes thereof

Publications (3)

Publication Number Publication Date
BRPI0905853A2 true BRPI0905853A2 (pt) 2015-06-30
BRPI0905853A8 BRPI0905853A8 (pt) 2019-01-29
BRPI0905853B1 BRPI0905853B1 (pt) 2019-03-26

Family

ID=41065638

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0905853-2A BRPI0905853B1 (pt) 2008-02-06 2009-02-05 Processo para a produção de proteínas recombinantes, melhorando a incorporação de fosfato.

Country Status (12)

Country Link
US (2) US8927256B2 (pt)
EP (2) EP2247737B1 (pt)
JP (1) JP5587795B2 (pt)
KR (2) KR101492011B1 (pt)
CN (2) CN103642843B (pt)
BR (1) BRPI0905853B1 (pt)
IL (2) IL207402A (pt)
MX (2) MX2010008654A (pt)
MY (1) MY161108A (pt)
RU (3) RU2556120C2 (pt)
SG (1) SG188126A1 (pt)
WO (1) WO2009113099A2 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0905853B1 (pt) * 2008-02-06 2019-03-26 Biocon Limited Processo para a produção de proteínas recombinantes, melhorando a incorporação de fosfato.
UA116217C2 (uk) 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
AU2013366692B2 (en) 2012-12-21 2017-11-23 Sanofi Dual GLP1/GIP or trigonal GLP1/GIP/Glucagon agonists
CN103911298B (zh) * 2012-12-31 2016-08-10 中粮营养健康研究院有限公司 培养基组合物和培养基及对菌株进行活菌计数的方法
WO2015086733A1 (en) 2013-12-13 2015-06-18 Sanofi Dual glp-1/glucagon receptor agonists
WO2015086728A1 (en) 2013-12-13 2015-06-18 Sanofi Exendin-4 peptide analogues as dual glp-1/gip receptor agonists
EP3080154B1 (en) 2013-12-13 2018-02-07 Sanofi Dual glp-1/gip receptor agonists
EP3080152A1 (en) 2013-12-13 2016-10-19 Sanofi Non-acylated exendin-4 peptide analogues
TW201625669A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
TW201625670A (zh) 2014-04-07 2016-07-16 賽諾菲公司 衍生自exendin-4之雙重glp-1/升糖素受體促效劑
TW201625668A (zh) 2014-04-07 2016-07-16 賽諾菲公司 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
US9932381B2 (en) 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists
DE102014216863B4 (de) 2014-08-25 2019-08-01 Hansgrohe Se Kopfbrause
AR105319A1 (es) 2015-06-05 2017-09-27 Sanofi Sa Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
TW201706291A (zh) 2015-07-10 2017-02-16 賽諾菲公司 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物
WO2017070200A1 (en) * 2015-10-20 2017-04-27 Buckman Laboratories International, Inc. Method to enhance yeast growth for fermentative bioproduct production, and nutrient composition for same
US20190212347A1 (en) * 2016-01-23 2019-07-11 Biocon Limited Bio-analytical method for insulin analogues
CN107022591B (zh) * 2017-05-11 2018-06-12 宜昌东阳光长江药业股份有限公司 一种提高胰岛素及其类似物前体表达的毕赤酵母发酵方法
WO2018216978A1 (en) * 2017-05-22 2018-11-29 Cj Healthcare Corporation Cell culture method at low temperature applicable to mass production of protein
CN107988292B (zh) * 2018-01-18 2023-12-26 江苏江山聚源生物技术有限公司 提高重组人源胶原蛋白稳定性的发酵工艺
CN111411049B (zh) * 2020-04-15 2022-11-22 北京惠之衡生物科技有限公司 一种提高胰岛素前体表达的毕赤酵母的发酵培养基及发酵方法
CN111996136A (zh) * 2020-07-24 2020-11-27 北大方正集团有限公司 一种荧光假单孢杆菌发酵培养基、培养方法与应用
CN114507609B (zh) * 2020-12-22 2023-04-18 益海嘉里(连云港)生物科技有限公司 一种提高磷脂酶c蛋白产量的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288554A (en) 1979-12-20 1981-09-08 Euteco Impianti S.P.A. Process for the cultivation of yeast cells
CN1017350B (zh) * 1987-08-12 1992-07-08 中国石油化工总公司 微生物发酵正烷烃生产长链α·ω-二羧酸的方法
US5830695A (en) * 1995-11-29 1998-11-03 Sankto Company, Limited Actinomycete promoter
CN1328369C (zh) * 1999-02-03 2007-07-25 药物研究所有限公司 培养物
AU3910000A (en) * 1999-03-22 2000-10-09 Zymogenetics Inc. Improved methods for producing proteins in transformed (pichia)
RU2141531C1 (ru) * 1999-05-26 1999-11-20 Российское акционерное общество открытого типа "Биопрепарат" Способ получения рекомбинантного инсулина человека
HUP9902352A1 (hu) * 1999-07-12 2000-09-28 Gyógyszerkutató Intézet Kft. Eljárás pravasztatin mikrobiológiai előállítására
EP1425304B9 (en) * 2001-07-11 2010-09-08 Maxygen, Inc. G-csf conjugates
KR100429925B1 (ko) * 2001-12-28 2004-05-03 씨제이 주식회사 5'-크산틸산을 생산하는 미생물
US20060234337A1 (en) * 2002-04-12 2006-10-19 Akira Arisawa Expression system for actinomycete-origin cytochrome p-450 in escherichia coli
RU2208637C1 (ru) * 2002-04-16 2003-07-20 Институт биоорганической химии им. М.М. Шемякина и Ю.А. Овчинникова РАН Способ получения генно-инженерного инсулина человека
WO2004039996A1 (en) 2002-11-01 2004-05-13 Cadila Healthcare Limited Mthod for producing recombinant human interferon alpha 2b polypeptide in pichia pastoris
KR100470078B1 (ko) * 2003-06-12 2005-02-04 씨제이 주식회사 컴팩틴을 프라바스타틴으로 전환할 수 있는 스트렙토마이세스 종(Streptomyces sp.)CJPV 975652 및 그를 이용한 프라바스타틴의 제조방법
US20050112737A1 (en) * 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
RU2278870C2 (ru) * 2004-08-30 2006-06-27 Закрытое Акционерное Общество "Биокад" Способ получения, выделения, очистки и стабилизации рекомбинантного гранулоцитарного колониестимулирующего фактора человека, пригодного для медицинского применения, и иммунобиологическое средство на его основе
WO2007005646A2 (en) 2005-07-01 2007-01-11 The University Of Florida Research Foundation, Inc. Recombinant host cells and media for ethanol production
MX2008011407A (es) * 2006-03-06 2008-09-24 Cadila Healthcare Ltd Proceso para preparar g-csf humano.
KR20080019928A (ko) * 2006-08-29 2008-03-05 충청북도 질소원으로 요소를 이용한 마이코페놀산 대량 생산 방법
PL215829B1 (pl) * 2007-11-05 2014-01-31 Skotan Spolka Akcyjna Nowy szczep Yarrowia lipolytica oraz jego zastosowanie do przemyslowej utylizacji frakcji glicerolowej uzyskiwanej w produkcji biodiesla
BRPI0905853B1 (pt) * 2008-02-06 2019-03-26 Biocon Limited Processo para a produção de proteínas recombinantes, melhorando a incorporação de fosfato.

Also Published As

Publication number Publication date
RU2011153811A (ru) 2013-07-10
CN101983242A (zh) 2011-03-02
KR20120066068A (ko) 2012-06-21
US20140141467A1 (en) 2014-05-22
RU2012145969A (ru) 2014-05-10
IL221379A (en) 2013-08-29
IL207402A (en) 2013-07-31
IL221379A0 (en) 2012-10-31
KR20100118592A (ko) 2010-11-05
EP2247737B1 (en) 2018-06-20
WO2009113099A3 (en) 2009-11-05
WO2009113099A2 (en) 2009-09-17
MY161108A (en) 2017-04-14
CN103642843A (zh) 2014-03-19
US9255285B2 (en) 2016-02-09
RU2595380C2 (ru) 2016-08-27
MX349413B (es) 2017-07-19
EP2565272A3 (en) 2013-07-03
KR101283734B1 (ko) 2013-07-08
EP2565272A2 (en) 2013-03-06
US20100317056A1 (en) 2010-12-16
CN103642843B (zh) 2017-03-01
KR101492011B1 (ko) 2015-02-10
EP2247737A2 (en) 2010-11-10
US8927256B2 (en) 2015-01-06
SG188126A1 (en) 2013-03-28
RU2556120C2 (ru) 2015-07-10
IL207402A0 (en) 2010-12-30
BRPI0905853B1 (pt) 2019-03-26
EP2247737A4 (en) 2012-03-14
JP5587795B2 (ja) 2014-09-10
MX2010008654A (es) 2010-10-06
CN101983242B (zh) 2015-12-16
RU2010137009A (ru) 2012-03-20
RU2491345C2 (ru) 2013-08-27
JP2011510677A (ja) 2011-04-07
BRPI0905853A8 (pt) 2019-01-29

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 26/03/2019, OBSERVADAS AS CONDICOES LEGAIS.