BRPI0906544A2 - método de obtenção de informação a partir de células isoladas de interesse. - Google Patents

método de obtenção de informação a partir de células isoladas de interesse.

Info

Publication number
BRPI0906544A2
BRPI0906544A2 BRPI0906544A BRPI0906544A BRPI0906544A2 BR PI0906544 A2 BRPI0906544 A2 BR PI0906544A2 BR PI0906544 A BRPI0906544 A BR PI0906544A BR PI0906544 A BRPI0906544 A BR PI0906544A BR PI0906544 A2 BRPI0906544 A2 BR PI0906544A2
Authority
BR
Brazil
Prior art keywords
interest
obtaining information
isolated cells
isolated
cells
Prior art date
Application number
BRPI0906544A
Other languages
English (en)
Inventor
Chen Chun-Nan
O Bowlby James
Aleck Jorgensen Richard
Original Assignee
Single Cell Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Single Cell Tech Inc filed Critical Single Cell Tech Inc
Publication of BRPI0906544A2 publication Critical patent/BRPI0906544A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00Methods specially adapted for identifying library members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
BRPI0906544A 2008-04-05 2009-04-03 método de obtenção de informação a partir de células isoladas de interesse. BRPI0906544A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7298508P 2008-04-05 2008-04-05
US14157908P 2008-12-30 2008-12-30
PCT/US2009/002122 WO2009123762A2 (en) 2008-04-05 2009-04-03 Method of screening single cells for the production of biologically active agents

Publications (1)

Publication Number Publication Date
BRPI0906544A2 true BRPI0906544A2 (pt) 2019-01-02

Family

ID=41135895

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906544A BRPI0906544A2 (pt) 2008-04-05 2009-04-03 método de obtenção de informação a partir de células isoladas de interesse.

Country Status (9)

Country Link
US (4) US9328172B2 (pt)
EP (1) EP2260112A4 (pt)
JP (1) JP5749156B2 (pt)
KR (1) KR101679869B1 (pt)
CN (1) CN102046809A (pt)
AU (1) AU2009232353B2 (pt)
BR (1) BRPI0906544A2 (pt)
CA (1) CA2720472C (pt)
WO (3) WO2009123762A2 (pt)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007035633A2 (en) 2005-09-16 2007-03-29 President & Fellows Of Harvard College Screening assays and methods
CA3170924A1 (en) * 2007-10-02 2009-04-09 Labrador Diagnostics Llc Modular point-of-care devices and uses thereof
US9328172B2 (en) 2008-04-05 2016-05-03 Single Cell Technology, Inc. Method of obtaining antibodies of interest and nucleotides encoding same
EP2356249B1 (en) * 2008-10-10 2016-02-17 Picovitro Ab Genetic analysis in microwells
US8569046B2 (en) * 2009-02-20 2013-10-29 Massachusetts Institute Of Technology Microarray with microchannels
EP2789694A1 (en) 2009-04-02 2014-10-15 Fluidigm Corporation Microfluidic device with reaction product recovery system
WO2012048341A1 (en) * 2010-10-08 2012-04-12 President And Fellows Of Harvard College High-throughput single cell barcoding
US10146906B2 (en) 2010-12-30 2018-12-04 Life Technologies Corporation Models for analyzing data from sequencing-by-synthesis operations
CN106323875B (zh) 2011-01-21 2019-07-09 西拉诺斯知识产权有限责任公司 样品使用最大化的系统和方法
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
EP3421592B1 (en) * 2011-04-28 2023-09-13 The Board of Trustees of the Leland Stanford Junior University Identification of polynucleotides associated with a sample
US9074204B2 (en) * 2011-05-20 2015-07-07 Fluidigm Corporation Nucleic acid encoding reactions
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US9619627B2 (en) 2011-09-25 2017-04-11 Theranos, Inc. Systems and methods for collecting and transmitting assay results
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US8840838B2 (en) 2011-09-25 2014-09-23 Theranos, Inc. Centrifuge configurations
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US9268915B2 (en) 2011-09-25 2016-02-23 Theranos, Inc. Systems and methods for diagnosis or treatment
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9250229B2 (en) 2011-09-25 2016-02-02 Theranos, Inc. Systems and methods for multi-analysis
WO2013090404A2 (en) * 2011-12-13 2013-06-20 Single Cell Technology, Inc. Method of screening a plurality of single secreting cells for functional activity
EP2809783A2 (en) 2012-02-02 2014-12-10 Invenra, Inc. High throughput screen for biologically active polypeptides
US9646132B2 (en) 2012-05-11 2017-05-09 Life Technologies Corporation Models for analyzing data from sequencing-by-synthesis operations
UA118441C2 (uk) 2012-10-08 2019-01-25 Протена Біосаєнсиз Лімітед Антитіло, що розпізнає альфа-синуклеїн
WO2015004632A1 (en) 2013-07-12 2015-01-15 Neotope Biosciences Limited Antibodies that recognize iapp
WO2015004633A1 (en) 2013-07-12 2015-01-15 Neotope Biosciences Limited Antibodies that recognize islet-amyloid polypeptide (iapp)
TWI503172B (zh) * 2013-09-03 2015-10-11 Nat Univ Tsing Hua 量測組件
JP6303347B2 (ja) * 2013-09-11 2018-04-04 大日本印刷株式会社 検体画像管理システム及び検体画像管理プログラム
JP5583830B1 (ja) 2013-09-27 2014-09-03 日本瓦斯株式会社 Lpガスメータの指針値入力チェックシステムおよび方法
CA2944402A1 (en) 2014-04-08 2015-10-15 Prothena Biosciences Limited Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
WO2016037051A1 (en) 2014-09-04 2016-03-10 Theranos, Inc. Pathogen and antimicrobial resistance testing
CN104561231B (zh) * 2015-01-23 2017-01-25 中国科学院重庆绿色智能技术研究院 一种测定浮游藻类细胞比增殖速率的方法
CA2981131C (en) * 2015-03-31 2024-02-06 Toray Industries, Inc. Analysis chip
CA3184363C (en) 2015-04-21 2024-01-02 Isolation Bio Inc. High resolution systems, kits, apparatus, and methods for high throughput microbiology applications
US11117113B2 (en) 2015-12-16 2021-09-14 Fluidigm Corporation High-level multiplex amplification
WO2017136734A1 (en) 2016-02-04 2017-08-10 Trianni, Inc. Enhanced production of immunoglobulins
EP3909679B1 (en) * 2016-08-10 2022-11-30 Roche Diagnostics GmbH Plate with wells for chemical or biological reactions, and method for multiple imaging of such a plate by means of an imaging system
AU2017345402A1 (en) * 2016-10-19 2019-05-23 General Automation Lab Technologies Inc. High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications
US11473081B2 (en) 2016-12-12 2022-10-18 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
CA3048904A1 (en) 2016-12-30 2018-07-05 xCella Biosciences, Inc. Multi-stage sample recovery system
CN107219351A (zh) * 2017-06-08 2017-09-29 广东省生物资源应用研究所 一种基于单细胞芯片技术的抗体筛选方法
JP2019100940A (ja) * 2017-12-06 2019-06-24 東ソー株式会社 未分化細胞を高感度に検出および回収する方法
EP3788146A4 (en) 2018-05-02 2022-06-01 The General Hospital Corporation HIGH RESOLUTION OF SPATIAL MACROMOLECULAR ABUNDANCE
US12116415B2 (en) 2018-10-09 2024-10-15 Single Cell Technology, Inc. Anti-BCMA antibodies
EP4371930B1 (en) 2018-12-06 2025-08-20 Xcella Biosciences, Inc. Lateral loading of microcapillary arrays
CN115667490A (zh) * 2020-05-26 2023-01-31 生物辐射实验室股份有限公司 用于快速数字检测的装置和方法
JP2024509971A (ja) 2021-03-11 2024-03-05 アイジェニックス, インコーポレイテッド アレルギー応答を予測するための方法およびシステム
CN113066539A (zh) * 2021-03-22 2021-07-02 上海商汤智能科技有限公司 预测方法及相关装置、设备

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4642284A (en) * 1983-06-13 1987-02-10 Scripps Clinic And Research Foundation Method and system for detection of complement pathway activation
US4876194A (en) * 1986-07-22 1989-10-24 Hightech Receptor Ab Protein L and subfragments thereof, with immunoglobulin binding activity, a process for preparing thereof, reagent kit, pharmaceutical composition and a peptococcus magnus strain
US5110556A (en) * 1986-10-28 1992-05-05 Costar Corporation Multi-well test plate
US5897475A (en) * 1994-10-05 1999-04-27 Antex Biologics, Inc. Vaccines comprising enhanced antigenic helicobacter spp.
US6091001A (en) 1995-03-29 2000-07-18 Abgenix, Inc. Production of antibodies using Cre-mediated site-specific recombination
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US5866330A (en) 1995-09-12 1999-02-02 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US7062219B2 (en) * 1997-01-31 2006-06-13 Odyssey Thera Inc. Protein fragment complementation assays for high-throughput and high-content screening
US6548263B1 (en) * 1997-05-29 2003-04-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
JP4313861B2 (ja) * 1997-08-01 2009-08-12 キヤノン株式会社 プローブアレイの製造方法
US6177282B1 (en) * 1997-08-12 2001-01-23 Mcintyre John A. Antigens embedded in thermoplastic
US6232066B1 (en) 1997-12-19 2001-05-15 Neogen, Inc. High throughput assay system
US6083682A (en) * 1997-12-19 2000-07-04 Glaxo Group Limited System and method for solid-phase parallel synthesis of a combinatorial collection of compounds
JP4387588B2 (ja) * 1998-02-04 2009-12-16 メルク エンド カムパニー インコーポレーテッド 高スループットスクリーニングアッセイ用仮想ウェル
US6087103A (en) 1998-03-04 2000-07-11 Lifespan Biosciences, Inc. Tagged ligand arrays for identifying target-ligand interactions
US20030027214A1 (en) * 1999-02-17 2003-02-06 Kamb Carl Alexander Methods for substrate-ligand interaction screening
CA2396320A1 (en) * 2000-01-11 2001-07-19 Maxygen, Inc. Integrated systems and methods for diversity generation and screening
US6818758B2 (en) * 2000-02-22 2004-11-16 Applera Corporation Estrogen receptor beta variants and methods of detection thereof
US6794141B2 (en) * 2000-12-22 2004-09-21 Arcturus Bioscience, Inc. Nucleic acid amplification
ATE538380T1 (de) 2001-01-23 2012-01-15 Harvard College Nukleinsäure-programmierbare protein-arrays
US7299134B2 (en) 2001-02-16 2007-11-20 Bio-Rad Laboratories, Inc. Method for correlating gene expression profiles with protein expression profiles
DK1392342T3 (en) * 2001-05-11 2015-12-21 Univ Yale Global analysis of protein activities using proteomchips
WO2003016574A1 (en) * 2001-08-16 2003-02-27 Zhifeng Shao Analysis of gene expression profiles using sequential hybridization
JP4754746B2 (ja) * 2001-09-28 2011-08-24 オリンパス株式会社 棒状担体およびこれを具備するシリンダー反応容器
US7521053B2 (en) * 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US20050142539A1 (en) 2002-01-14 2005-06-30 William Herman Targeted ligands
AU2003202026A1 (en) * 2002-01-16 2003-09-02 Dynal Biotech Asa Method for isolating nucleic acids and protein from a single sample
EP1534509A2 (en) * 2002-08-28 2005-06-01 Bionexus Ventures L.L.C. Screening for cell-targeting ligands attached to metal nanoshells for use in target-cell killing
DK1566635T3 (da) * 2002-11-14 2012-03-19 Vivalis Chip med array af mikrobrønde til påvisning af antigenspecifik lymfocyt, fremgangsmåde til påvisning af antigenspecifik lymfocyt og fremgangsmåde til kloning af antigenspecifik lymfocyt-antigenreceptorgen
JP3723882B2 (ja) * 2002-11-14 2005-12-07 篤 村口 抗原特異的リンパ球検出用マイクロウェルアレイチップ、抗原特異的リンパ球の検出法及び製造方法
JP3738308B2 (ja) * 2002-11-29 2006-01-25 篤 村口 抗原特異的リンパ球抗原受容体遺伝子のクローニング方法
US8574590B2 (en) 2003-07-30 2013-11-05 Integral Molecular, Inc. Lipoparticles comprising proteins, methods of making, and using the same
US20060223194A1 (en) * 2005-04-01 2006-10-05 Viorica Lopez-Avila Methods of screening for post-translationally modified proteins
EP1891240A4 (en) * 2005-06-03 2010-04-21 David E Kohne METHOD FOR GENERATING IMPROVED GENE EXPRESSION ANALYSIS AND GENE EXPRESSION ANALYSIS COMPARISON TEST RESULTS
WO2007035633A2 (en) 2005-09-16 2007-03-29 President & Fellows Of Harvard College Screening assays and methods
WO2007076580A1 (en) 2005-12-30 2007-07-12 Bio-Layer Pty Limited Binding of molecules
US8021877B2 (en) * 2006-04-10 2011-09-20 Massachusetts Institute Of Technology Particle patterning chip
US20080004185A1 (en) * 2006-06-12 2008-01-03 Antara Biosciences Inc. Three dimensional array
WO2007147018A1 (en) * 2006-06-14 2007-12-21 Cellpoint Diagnostics, Inc. Analysis of rare cell-enriched samples
EP3424598B1 (en) * 2006-06-14 2022-06-08 Verinata Health, Inc. Rare cell analysis using sample splitting and dna tags
EP2121983A2 (en) * 2007-02-02 2009-11-25 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
CA3170924A1 (en) * 2007-10-02 2009-04-09 Labrador Diagnostics Llc Modular point-of-care devices and uses thereof
US8304245B2 (en) * 2007-11-02 2012-11-06 Children's Hospital And Research Center At Oakland Microfluidic flow lysometer device, system and method
US9328172B2 (en) 2008-04-05 2016-05-03 Single Cell Technology, Inc. Method of obtaining antibodies of interest and nucleotides encoding same
BR112013004691A2 (pt) * 2010-08-30 2017-11-21 Dow Agrosciences Llc construto de dna de ativação gênica marcada de milho, população marcada de plantas de milho, método para geração da mesma e método para gerar uma planta de milho marcada

Also Published As

Publication number Publication date
WO2009123756A1 (en) 2009-10-08
US20100035763A1 (en) 2010-02-11
US20160201054A1 (en) 2016-07-14
US9873871B2 (en) 2018-01-23
US9328172B2 (en) 2016-05-03
CA2720472C (en) 2018-01-02
US20110190148A1 (en) 2011-08-04
EP2260112A2 (en) 2010-12-15
WO2009123762A2 (en) 2009-10-08
WO2009123762A3 (en) 2009-12-30
CA2720472A1 (en) 2009-10-08
EP2260112A4 (en) 2013-10-09
AU2009232353A1 (en) 2009-10-08
WO2009123748A1 (en) 2009-10-08
CN102046809A (zh) 2011-05-04
JP5749156B2 (ja) 2015-07-15
US8309035B2 (en) 2012-11-13
AU2009232353B2 (en) 2015-04-30
KR20100131517A (ko) 2010-12-15
JP2011516064A (ja) 2011-05-26
KR101679869B1 (ko) 2016-11-25
US8309317B2 (en) 2012-11-13
US20090280992A1 (en) 2009-11-12

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]