BRPI0906750A2 - Material polimérico biocompatível poroso e métodos - Google Patents

Material polimérico biocompatível poroso e métodos

Info

Publication number
BRPI0906750A2
BRPI0906750A2 BRPI0906750-7A BRPI0906750A BRPI0906750A2 BR PI0906750 A2 BRPI0906750 A2 BR PI0906750A2 BR PI0906750 A BRPI0906750 A BR PI0906750A BR PI0906750 A2 BRPI0906750 A2 BR PI0906750A2
Authority
BR
Brazil
Prior art keywords
methods
polymeric material
biocompatible polymeric
porous biocompatible
porous
Prior art date
Application number
BRPI0906750-7A
Other languages
English (en)
Inventor
Sean Hamilton Kerr
Ali Recber
Thomas Pepe
Lawton Laurence
Ryan Walsh
Thomas Kuennzi
Rhandall Brandon
Dominique Messerli
Original Assignee
Synthes Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthes Gmbh filed Critical Synthes Gmbh
Publication of BRPI0906750A2 publication Critical patent/BRPI0906750A2/pt
Publication of BRPI0906750B1 publication Critical patent/BRPI0906750B1/pt
Publication of BRPI0906750B8 publication Critical patent/BRPI0906750B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/24—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by surface fusion and bonding of particles to form voids, e.g. sintering
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61F2/44—Joints for the spine, e.g. vertebrae or spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae or spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A—HUMAN NECESSITIES
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    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00976—Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2361/00—Characterised by the use of condensation polymers of aldehydes or ketones; Derivatives of such polymers
    • C08J2361/04—Condensation polymers of aldehydes or ketones with phenols only
    • C08J2361/16—Condensation polymers of aldehydes or ketones with phenols only of ketones with phenols

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Prostheses (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Materials For Medical Uses (AREA)
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Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59903490D1 (de) 1998-09-11 2003-01-02 Schmidmaier Gerhard Biologisch aktive implantate
CA2667000A1 (en) 2006-09-25 2008-04-03 James P. Murphy Bioactive load-bearing composites comprising peek and bioglass particles
US11179243B2 (en) 2007-02-28 2021-11-23 Happe Spine Llc Implantable devices
US20080206297A1 (en) 2007-02-28 2008-08-28 Roeder Ryan K Porous composite biomaterials and related methods
EP2238192B1 (en) 2008-02-01 2017-03-01 Synthes GmbH Porous biocompatible polymer material and methods
RU2524131C2 (ru) * 2008-12-05 2014-07-27 Акесо Медикал Имэджинг Б.В. Способ оптического детектирования и устройство для оптического детектирования состояния суставов
US20100168798A1 (en) * 2008-12-30 2010-07-01 Clineff Theodore D Bioactive composites of polymer and glass and method for making same
US8821555B2 (en) 2009-02-11 2014-09-02 Howmedica Osteonics Corp. Intervertebral implant with integrated fixation
CN102612351A (zh) * 2009-09-23 2012-07-25 捷迈脊柱有限公司 复合植入体
JP2011078624A (ja) * 2009-10-08 2011-04-21 Nagoya Univ 傾斜構造リン酸カルシウム含有複合層をもつ樹脂複合体とその製造方法
US8840668B1 (en) 2009-11-11 2014-09-23 Nuvasive, Inc. Spinal implants, instruments and related methods
US8740983B1 (en) 2009-11-11 2014-06-03 Nuvasive, Inc. Spinal fusion implants and related methods
BR112012012603B1 (pt) * 2009-11-25 2019-03-19 Difusion Technologies, Inc. Método de pós-carregamento de partículas de cerâmica com cátions metálicos antimicrobianos e método de conferir atividade antimicrobiana a um dispositivo através do controle da liberação de cátions antimicrobianos a partir do referido dispositivo por meio de troca iônica
US8821912B2 (en) 2009-12-11 2014-09-02 Difusion Technologies, Inc. Method of manufacturing antimicrobial implants of polyetheretherketone
MX2012012710A (es) 2010-05-07 2013-02-26 Difusion Technologies Inc Implantes medicos con hidrofilicidad incrementada.
CN101999952A (zh) * 2010-12-17 2011-04-06 东华大学 一种pcl与pla人体可吸收血管支架及其制备方法
US9468535B2 (en) * 2010-12-17 2016-10-18 K2M, Inc. Interbody spacer
US9132021B2 (en) 2011-10-07 2015-09-15 Pioneer Surgical Technology, Inc. Intervertebral implant
EP2641621A1 (en) * 2012-03-23 2013-09-25 Elos Medtech Pinol A/S Strontium based coating for body implants
WO2014008369A1 (en) * 2012-07-03 2014-01-09 Massachusetts Institute Of Technology Radiolucent cranial implants for neural applications
RU2015104581A (ru) * 2012-07-16 2016-09-10 Смит Энд Нефью, Инк. Устройство для закрытия раны с использованием отрицательного давления
BR112015003629A2 (pt) 2012-08-21 2017-07-04 Avery Dennison Corp sistemas e métodos para a feitura de filmes, fibras, esferas e outros artigos porosos
US10124098B2 (en) 2013-03-13 2018-11-13 Smith & Nephew, Inc. Negative pressure wound closure device and systems and methods of use in treating wounds with negative pressure
JP5899376B2 (ja) 2013-09-24 2016-04-06 日本特殊陶業株式会社 生体インプラント及びその製造方法
USD745159S1 (en) 2013-10-10 2015-12-08 Nuvasive, Inc. Intervertebral implant
WO2015061352A2 (en) 2013-10-21 2015-04-30 Smith & Nephew, Inc. Negative pressure wound closure device
EP3087958B1 (en) 2013-12-24 2019-10-30 Nipro Corporation Stent
CN105147420B (zh) * 2014-06-03 2017-07-28 深圳兰度生物材料有限公司 人工椎间盘及其制备方法
US9504550B2 (en) 2014-06-26 2016-11-29 Vertera, Inc. Porous devices and processes for producing same
US9498922B2 (en) 2014-06-26 2016-11-22 Vertera, Inc. Apparatus and process for producing porous devices
EP3795183A1 (en) * 2014-08-06 2021-03-24 Poriferous, LLC Implant with porous outer cortical layer
USD858769S1 (en) 2014-11-20 2019-09-03 Nuvasive, Inc. Intervertebral implant
AU2016200179B2 (en) 2015-01-14 2020-09-17 Stryker European Operations Holdings Llc Spinal implant with porous and solid surfaces
AU2016200195B2 (en) 2015-01-14 2020-07-02 Vb Spine Llc Spinal implant with fluid delivery capabilities
US10537373B2 (en) * 2015-04-24 2020-01-21 Biomet Sports Medicine, Llc Porous implants with injectable capabilities
CA2930123A1 (en) 2015-05-18 2016-11-18 Stryker European Holdings I, Llc Partially resorbable implants and methods
CN104958100A (zh) * 2015-05-25 2015-10-07 创生医疗器械(中国)有限公司 一种椎弓根螺钉用防旋顶丝
USD815281S1 (en) 2015-06-23 2018-04-10 Vertera, Inc. Cervical interbody fusion device
FR3039157B1 (fr) * 2015-07-22 2019-06-28 Arkema France Composition a base de polyarylene-ether-cetone (paek) stable a l'etat fondu et procede de stabilisation d'une telle composition
US12258462B2 (en) 2015-07-22 2025-03-25 Arkema France Composition made from poly(arylene-ether-ketone) (PAEK) which is stable in the molten state and method for stabilizing such a composition
CN105233335B (zh) * 2015-11-06 2018-07-13 四川大学 一种具有生物活性的多孔聚芳醚酮材料及其制备方法与应用
US10251752B2 (en) 2015-12-31 2019-04-09 DePuy Synthes Products, Inc. Modular femoral prosthesis system for hip arthroplasty
US10660764B2 (en) * 2016-06-14 2020-05-26 The Trustees Of The Stevens Institute Of Technology Load sustaining bone scaffolds for spinal fusion utilizing hyperbolic struts and translational strength gradients
JP6769756B2 (ja) * 2016-07-01 2020-10-14 日本特殊陶業株式会社 椎体スペーサ
CN106178105B (zh) * 2016-08-29 2019-12-10 上海交通大学 一种表面多孔的医用聚醚醚酮及其制备方法和应用
KR101958952B1 (ko) * 2017-04-13 2019-03-15 김정성 하중 저항력이 향상된 다공성 구조의 척추 케이지
US10687960B2 (en) * 2017-04-25 2020-06-23 Second Affiliated Hospital Of Second Military Mediccal University, Shanghai Assembled vertebral body
KR101977065B1 (ko) * 2017-09-01 2019-05-13 건양대학교 산학협력단 다공성 구조를 가진 척추체 유합 임플란트
CA3074834C (en) 2017-09-08 2025-09-16 Xtant Medical Holdings, Inc. INTERVERTEBRAL IMPLANTS, INSTRUMENTS AND PROCESSES
EP3459502B1 (en) 2017-09-20 2024-05-22 Stryker European Operations Holdings LLC Spinal implants
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
US11766339B1 (en) 2017-10-24 2023-09-26 Omnia Medical, LLC Multi-material multi-component spinal implant
US10736752B1 (en) * 2017-10-24 2020-08-11 Omnia Medical, LLC Multi-material multi-component spinal implant
KR102106312B1 (ko) * 2017-12-12 2020-05-29 주식회사 오쎄인 페이스트 형태의 골 대체용 합성골 및 이의 제조방법
JP2019180796A (ja) * 2018-04-09 2019-10-24 日本特殊陶業株式会社 椎体スペーサ
US10517739B2 (en) 2018-05-08 2019-12-31 Globus Medical, Inc. Intervertebral spinal implant
US10744003B2 (en) 2018-05-08 2020-08-18 Globus Medical, Inc. Intervertebral spinal implant
US10682238B2 (en) 2018-05-08 2020-06-16 Globus Medical, Inc. Intervertebral spinal implant
AU2019213392B2 (en) 2018-08-09 2024-11-28 Vb Spine Llc Interbody implants and optimization features thereof
US10729557B2 (en) 2018-08-21 2020-08-04 Warsaw Orthopedic, Inc. Porous surgical implant and method of making same
EP3662870A1 (en) * 2018-12-05 2020-06-10 SMed - TA/TD LLC Adjusted stiffness orthopaedic implants and method of manufacture
US11039931B2 (en) 2019-02-01 2021-06-22 Globus Medical, Inc. Intervertebral spinal implant
CN113811266A (zh) * 2019-03-12 2021-12-17 哈佩脊椎有限责任公司 具有热塑性复合体的可植入医疗装置和用于形成热塑性复合体的方法
CN110393610B (zh) * 2019-05-15 2021-08-10 上海大学 一种三层复合骨植入假体及其制备方法
US11576787B2 (en) 2019-09-30 2023-02-14 DePuy Synthes Products, Inc. Patient specific femoral prosthesis
US11351034B2 (en) 2019-09-30 2022-06-07 DePuy Synthes Products, Inc. Patient specific femoral prosthesis
KR102287890B1 (ko) * 2019-11-20 2021-08-09 윤설아 두개악안면부 재건용 임플란트의 제조방법 및 이를 이용해 제조된 임플란트
TWM598130U (zh) * 2019-12-19 2020-07-11 謝瑞洋 用於植入個體骨體內或骨體間之支撐件、支撐件組合以及與其對應之導模板推入件及夯棒
US20210402052A1 (en) 2020-06-30 2021-12-30 Difusion, Inc. Medical Implants And Methods Of Manufacture
US20220183846A1 (en) 2020-12-10 2022-06-16 Depuy Ireland Unlimited Company Acetabular implant with predetermined modulus and method of manufacturing same
KR102384715B1 (ko) * 2021-08-26 2022-04-11 (주)제일메디칼코퍼레이션 골 유착능이 우수한 다공성 생체 임플란트 및 이의 제조방법
CN114642770A (zh) * 2022-03-22 2022-06-21 中国人民解放军总医院第一医学中心 一种植入复合材料及其制备方法和应用
CN115737920B (zh) * 2022-12-19 2024-02-23 北京德益达美医疗科技有限公司 一种医用复合材料及其制备方法和应用
US12232790B2 (en) 2022-12-30 2025-02-25 IvyTech Design LLC Adjustable angle orthopedic distractor, compressor, and distractor-compressor
EP4473946B1 (en) * 2023-06-07 2026-03-11 Biedermann Technologies GmbH & Co. KG Implant for engagement between vertebrae and implant kit
CN120458782A (zh) * 2025-07-14 2025-08-12 四川华曙图灵增材制造技术有限责任公司 一种椎间融合器及其制备方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430760A (en) * 1981-12-18 1984-02-14 Collagen Corporation Nonstress-bearing implantable bone prosthesis
JPS5823835A (ja) * 1981-08-05 1983-02-12 Mitsubishi Chem Ind Ltd 多孔質焼結体
JPS59197439A (ja) * 1983-04-26 1984-11-09 Asahi Chem Ind Co Ltd 親水性多孔質焼結体
AU624627B2 (en) * 1988-08-18 1992-06-18 Johnson & Johnson Orthopaedics, Inc. Functional and biocompatible intervertebral disc spacer containing elastomeric material of varying hardness
JPH04146762A (ja) * 1990-10-11 1992-05-20 Terumo Corp 硬組織補綴材料およびその製造方法
US5651931A (en) * 1994-01-27 1997-07-29 Upchurch Scientific, Inc. Method of making a biocompatible filter
GB9606818D0 (en) * 1996-03-30 1996-06-05 Gore W L & Ass Uk Granular-type modified polytetrafluoroethlyene dispersions and fused articles prepared therefrom (Case A)
US6458162B1 (en) * 1999-08-13 2002-10-01 Vita Special Purpose Corporation Composite shaped bodies and methods for their production and use
DE50013602D1 (de) * 1999-12-15 2006-11-23 Zimmer Gmbh Intervertebrales Implantat
US7758882B2 (en) 2000-01-31 2010-07-20 Indiana University Research And Technology Corporation Composite biomaterial including anisometric calcium phosphate reinforcement particles and related methods
EP1132058A1 (en) * 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravascular prothesis
DE20020649U1 (de) * 2000-12-06 2002-04-11 stryker Trauma GmbH, 24232 Schönkirchen Vorrichtung für den chirurgischen oder therapeutischen Gebrauch, insbesondere Implantate und chirurgische Instrumente sowie deren Zubehör
EP1357863B1 (en) * 2001-01-02 2010-11-10 Advanced Ceramics Research, Inc. Compositions and methods for biomedical applications
JP2003210570A (ja) * 2002-01-18 2003-07-29 Olympus Optical Co Ltd 生体活性層を有するインプラント材およびインプラント基材への生体活性層の被覆方法
DE20205016U1 (de) * 2002-03-30 2003-08-14 Mathys Medizinaltechnik Ag, Bettlach Chirurgisches Implantat
KR100529209B1 (ko) * 2002-08-28 2005-11-17 한국과학기술연구원 세포 친화성이 향상된 생분해성의 조직 공학용 다공성고분자 지지체의 제조방법
US20050287071A1 (en) * 2002-12-03 2005-12-29 Kyphon Inc. Formulation for a cement preparation as bone substitute
EP1433489A1 (en) * 2002-12-23 2004-06-30 Degradable Solutions AG Biodegradable porous bone implant with a barrier membrane sealed thereto
FR2848856B1 (fr) * 2002-12-24 2007-05-25 Cadorel Catherine Materiau a usage medical ou veterinaire, son procede d'obtention et ses applications
US8298292B2 (en) * 2003-04-16 2012-10-30 Howmedica Osteonics Corp. Craniofacial implant
CA2533534C (en) * 2003-07-24 2013-03-19 Tecomet, Inc. Assembled non-random foams
AU2005211722B2 (en) * 2004-02-05 2011-06-02 Osteobiologics, Inc. Absorbable orthopedic implants
GB0422666D0 (en) * 2004-10-12 2004-11-10 Benoist Girard Sas Prosthetic acetabular cups
RU2406612C2 (ru) * 2005-07-15 2010-12-20 Тонен Кемикал Корпорейшн Многослойная микропористая полиолефиновая мембрана и сепаратор для аккумуляторной батареи
DE102005039976A1 (de) 2005-08-23 2007-03-08 Basf Ag Partikel aus expandierbarem Polystyrol und daraus erhältliche Formteile mit verbessertem Brandverhalten
PL1919988T5 (pl) * 2005-08-23 2016-05-31 Basf Se Sposób wytwarzania płyt z tworzywa piankowego
US8029575B2 (en) * 2005-10-25 2011-10-04 Globus Medical, Inc. Porous and nonporous materials for tissue grafting and repair
EP1948722B1 (en) * 2005-11-04 2014-09-03 PPD Meditech Method for fabricating porous material
WO2007068489A2 (en) * 2005-12-14 2007-06-21 Scil Technology Gmbh A moldable biomaterial for bone regeneration
DE102006042142A1 (de) * 2006-09-06 2008-03-27 Curasan Ag Phasen- und sedimentationsstabile, plastisch verformbare Zubereitung mit intrinsischer Porenbildung, bspw. zum Auffüllen von Knochendefekten bzw. zur Verwendung als Knochenersatzmaterial, und Verfahren zu deren Herstellung
US8637064B2 (en) * 2006-09-20 2014-01-28 Warsaw Orthopedic, Inc. Compression molding method for making biomaterial composites
US20080206297A1 (en) * 2007-02-28 2008-08-28 Roeder Ryan K Porous composite biomaterials and related methods
EP2238192B1 (en) 2008-02-01 2017-03-01 Synthes GmbH Porous biocompatible polymer material and methods

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US20140207237A1 (en) 2014-07-24
WO2009099559A2 (en) 2009-08-13
US20160184483A1 (en) 2016-06-30
BRPI0906750B8 (pt) 2021-07-27
AU2009210750A1 (en) 2009-08-13
KR101618887B1 (ko) 2016-05-09
US11679181B2 (en) 2023-06-20
WO2009099559A3 (en) 2010-03-25
CA2711403C (en) 2016-08-09
JP2011511128A (ja) 2011-04-07
CA2711403A1 (en) 2009-08-13
KR20100120173A (ko) 2010-11-12
US20110045087A1 (en) 2011-02-24
CN101952341B (zh) 2016-03-23
EP2238192A2 (en) 2010-10-13
JP5726536B2 (ja) 2015-06-03
CN105754132A (zh) 2016-07-13
US8530560B2 (en) 2013-09-10
EP2238192B1 (en) 2017-03-01
US20200139014A1 (en) 2020-05-07
BRPI0906750B1 (pt) 2019-12-10
CN101952341A (zh) 2011-01-19
US9308297B2 (en) 2016-04-12
US10549014B2 (en) 2020-02-04
CN105754132B (zh) 2019-12-10

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