BRPI0907525A2 - Processo para iodização de compostos aromáticos - Google Patents

Processo para iodização de compostos aromáticos

Info

Publication number
BRPI0907525A2
BRPI0907525A2 BRPI0907525-9A BRPI0907525A BRPI0907525A2 BR PI0907525 A2 BRPI0907525 A2 BR PI0907525A2 BR PI0907525 A BRPI0907525 A BR PI0907525A BR PI0907525 A2 BRPI0907525 A2 BR PI0907525A2
Authority
BR
Brazil
Prior art keywords
iodization
aromatic compounds
aromatic
compounds
Prior art date
Application number
BRPI0907525-9A
Other languages
English (en)
Inventor
Luciano Lattuada
Camilla Cavallotti
Giovanni Battista Giovenzana
Fulvio Uggeri
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Publication of BRPI0907525A2 publication Critical patent/BRPI0907525A2/pt
Publication of BRPI0907525B1 publication Critical patent/BRPI0907525B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B39/00—Halogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/07—Oxygen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/09—Nitrogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/11—Halogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/27—Halogenation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
BRPI0907525-9A 2008-02-20 2009-02-16 Processo para iodização de compostos aromáticos BRPI0907525B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20080151661 EP2093206A1 (en) 2008-02-20 2008-02-20 Process for the iodination of aromatic compounds
EP08151661.9 2008-02-20
PCT/EP2009/051747 WO2009103666A2 (en) 2008-02-20 2009-02-16 Process for the iodination of aromatic compounds

Publications (2)

Publication Number Publication Date
BRPI0907525A2 true BRPI0907525A2 (pt) 2015-07-28
BRPI0907525B1 BRPI0907525B1 (pt) 2018-01-02

Family

ID=39650549

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0907525-9A BRPI0907525B1 (pt) 2008-02-20 2009-02-16 Processo para iodização de compostos aromáticos

Country Status (20)

Country Link
US (1) US9193659B2 (pt)
EP (2) EP2093206A1 (pt)
JP (1) JP5611057B2 (pt)
KR (1) KR101622552B1 (pt)
CN (1) CN101970381B (pt)
AU (1) AU2009216783B2 (pt)
BR (1) BRPI0907525B1 (pt)
CA (1) CA2715430C (pt)
ES (1) ES2589961T3 (pt)
HR (1) HRP20161137T1 (pt)
HU (1) HUE030008T2 (pt)
IL (1) IL207640A (pt)
MX (1) MX362895B (pt)
NZ (1) NZ586944A (pt)
PL (1) PL2254850T3 (pt)
PT (1) PT2254850T (pt)
RU (1) RU2469997C2 (pt)
SG (1) SG176522A1 (pt)
WO (1) WO2009103666A2 (pt)
ZA (1) ZA201005285B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2243767A1 (en) 2009-04-21 2010-10-27 Bracco Imaging S.p.A Process for the iodination of aromatic compounds
JP5661762B2 (ja) 2009-07-07 2015-01-28 ブラッコ・イメージング・ソシエタ・ペル・アチオニBracco Imaging S.P.A. ヨウ素化剤の製造方法
EP2394984A1 (en) * 2010-06-10 2011-12-14 Bracco Imaging S.p.A Process for the iodination of phenolic derivatives
CN103086915A (zh) * 2011-10-31 2013-05-08 上海海神化学生物科技有限公司 制备3,5-二取代-2,4,6-三碘代芳香胺类化合物的碘化方法
PL3066071T3 (pl) 2013-11-05 2018-09-28 Bracco Imaging S.P.A Sposób otrzymywania jopamidolu
CN106103407B (zh) 2014-03-04 2020-10-16 大塚制药株式会社 碘海醇粉末及其使用方法
RU2558037C1 (ru) * 2014-07-14 2015-07-27 Общество с ограниченной ответственностью "Научно-производственная фирма ЛиноРМ" ООО "НПФ ЛиноРМ" Способ получения линойодола
JP6743781B2 (ja) * 2016-08-08 2020-08-19 信越化学工業株式会社 レジスト材料及びパターン形成方法
WO2018104228A1 (en) 2016-12-05 2018-06-14 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates
CN108505063B (zh) * 2018-04-19 2019-11-05 华南理工大学 一种n-(3,5-二甲基-4-羟基苯基)乙酰胺的电化学制备方法
US11833621B2 (en) 2018-05-08 2023-12-05 Koki Company Limited Flux and solder material
CN113351186B (zh) * 2021-06-18 2022-12-27 海南希源化工科技有限公司 一种碘吸附剂的制备方法及所得产品和应用
CN113563399B (zh) * 2021-07-22 2023-06-27 中国科学院南海海洋研究所 一种制备碘化台勾霉素b和其它几种芳香类碘化产物的方法和应用
WO2023046815A1 (en) 2021-09-24 2023-03-30 Bracco Imaging Spa Electrochemical iodination of n,n'-(2,3-dihydroxypropyl)-5-hydroxy-1,3-benzenedicarboxamide
EP4514771B1 (en) 2022-04-29 2026-04-15 Bracco Imaging SPA Process for the preparation of 2,4,6-triiodophenol derivatives

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3647864A (en) * 1967-11-16 1972-03-07 Sterling Drug Inc 5-substituted-1 3-benzenediacrylic and -dipropionic acids
BE795902A (fr) * 1972-02-25 1973-08-23 Rhone Poulenc Sa Procede de preparation du diiodo-3,5 hydroxy-4benzonitrile et de l'iodo-3 hydroxy-4 nitro-5benzonitrile
CH608189A5 (pt) 1974-12-13 1978-12-29 Savac Ag
DD124516A1 (pt) 1975-11-14 1977-03-02
GB1548594A (en) 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
US4396598A (en) 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
EP0365541B1 (en) 1987-05-22 1992-08-12 BRACCO S.p.A. Preparation of 5-acylamino-2,4,6-triiodo- or tribromo-benzoic acid derivatives
JPH0735243B2 (ja) 1987-11-27 1995-04-19 三井東圧化学株式会社 一塩化沃素の製造方法
JPH0735244B2 (ja) 1987-12-18 1995-04-19 三井東圧化学株式会社 一塩化沃素の製造方法
US5013865A (en) 1988-04-06 1991-05-07 Mallinckrodt, Inc. Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds
CA2002599A1 (en) 1988-11-25 1990-05-25 Eastman Chemical Company Process for the electrochemical iodination of aromatic compounds
IL94718A (en) 1989-07-05 1994-10-21 Schering Ag Carboxamide non-ionic contrast media and method for the preparation thereof
FR2673180B1 (fr) 1991-02-25 1994-03-04 Guerbet Sa Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant.
IT1256248B (it) 1992-12-24 1995-11-29 Bracco Spa Formulazioni iniettabili acquose per radiodiagnostica comprendenti miscele di composti aromatici iodurati utili come agenti opacizzanti ai raggi x
US5763650A (en) 1995-05-23 1998-06-09 Fructamine S.P.A. Process for the preparation of a halosubstituted aromatic acid
US5575905A (en) 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
JP3985034B2 (ja) * 1995-05-24 2007-10-03 ジーイー・ヘルスケア・アクスイェ・セルスカプ ヨウ素化方法
IT1277339B1 (it) 1995-07-25 1997-11-10 Bracco Spa Processo per la produzione di agenti contrastografici iodurati
IT1289520B1 (it) 1996-12-24 1998-10-15 Zambon Spa Processo per la preparazione di un intermedio utile nella sintesi di mezzi di contrasto iodurati
IT1303797B1 (it) 1998-11-27 2001-02-23 Bracco Spa Processo per la preparazione di n,n'-bis(2,3-diidrossipropil)-5-((idrossiacetil)metilammino)-2,4,6-triiodo-1,3-benzendicarbossammide.
JP2000264605A (ja) 1999-03-19 2000-09-26 Hiroyuki Nakazawa 一塩化ヨウ素水溶液の製造方法
RU2278816C2 (ru) 2004-04-02 2006-06-27 ОАО "Троицкий йодный завод" Способ получения раствора солянокислого йода однохлористого
EP1837324B1 (en) 2005-01-06 2012-02-01 Nippoh Chemicals Co., Ltd Process for producing aromatic iodine compound
EP2123795B1 (en) 2007-03-09 2015-05-06 Japan Science and Technology Agency Method for producing iodizing agent and method for producing aromatic iodine compound

Also Published As

Publication number Publication date
US20100331567A1 (en) 2010-12-30
EP2254850B1 (en) 2016-06-22
IL207640A0 (en) 2010-12-30
PT2254850T (pt) 2016-08-29
HRP20161137T1 (hr) 2016-11-04
AU2009216783A1 (en) 2009-08-27
KR101622552B1 (ko) 2016-05-19
US9193659B2 (en) 2015-11-24
MX2010009184A (es) 2010-09-10
WO2009103666A3 (en) 2009-12-23
WO2009103666A2 (en) 2009-08-27
KR20100116594A (ko) 2010-11-01
PL2254850T3 (pl) 2016-12-30
CA2715430A1 (en) 2009-08-27
JP5611057B2 (ja) 2014-10-22
AU2009216783B2 (en) 2013-03-07
HUE030008T2 (en) 2017-04-28
CA2715430C (en) 2017-07-04
MX362895B (es) 2019-02-22
EP2093206A1 (en) 2009-08-26
BRPI0907525B1 (pt) 2018-01-02
RU2010138570A (ru) 2012-03-27
ES2589961T3 (es) 2016-11-17
NZ586944A (en) 2012-06-29
IL207640A (en) 2016-10-31
JP2011512381A (ja) 2011-04-21
RU2469997C2 (ru) 2012-12-20
SG176522A1 (en) 2011-12-29
ZA201005285B (en) 2011-04-28
CN101970381A (zh) 2011-02-09
CN101970381B (zh) 2013-10-23
EP2254850A2 (en) 2010-12-01

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]