BRPI0907624A2 - tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito - Google Patents

tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito

Info

Publication number
BRPI0907624A2
BRPI0907624A2 BRPI0907624A BRPI0907624A BRPI0907624A2 BR PI0907624 A2 BRPI0907624 A2 BR PI0907624A2 BR PI0907624 A BRPI0907624 A BR PI0907624A BR PI0907624 A BRPI0907624 A BR PI0907624A BR PI0907624 A2 BRPI0907624 A2 BR PI0907624A2
Authority
BR
Brazil
Prior art keywords
prevention
growth factor
heart disease
hepatocyte growth
disease treatment
Prior art date
Application number
BRPI0907624A
Other languages
English (en)
Inventor
Jong-Mook Kim
Sujeong Kim
Woong Hahn
Original Assignee
Viromed Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viromed Co Ltd filed Critical Viromed Co Ltd
Publication of BRPI0907624A2 publication Critical patent/BRPI0907624A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1833Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BRPI0907624A 2008-01-25 2009-01-28 tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito BRPI0907624A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2375608P 2008-01-25 2008-01-25
PCT/KR2009/000406 WO2009093880A2 (en) 2008-01-25 2009-01-28 Treatment and prevention of cardiac conditions using two or more isoforms of hepatocyte growth factor

Publications (1)

Publication Number Publication Date
BRPI0907624A2 true BRPI0907624A2 (pt) 2016-08-16

Family

ID=40901564

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0907624A BRPI0907624A2 (pt) 2008-01-25 2009-01-28 tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito

Country Status (14)

Country Link
US (1) US20090202606A1 (pt)
EP (1) EP2252321B1 (pt)
JP (1) JP5563991B2 (pt)
KR (1) KR101325674B1 (pt)
CN (1) CN101925362A (pt)
AU (1) AU2009206869B2 (pt)
BR (1) BRPI0907624A2 (pt)
CA (1) CA2712078C (pt)
DK (1) DK2252321T3 (pt)
ES (1) ES2537971T3 (pt)
MX (1) MX2010007887A (pt)
PT (1) PT2252321E (pt)
RU (1) RU2448159C1 (pt)
WO (1) WO2009093880A2 (pt)

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JP5579164B2 (ja) * 2008-04-09 2014-08-27 ビロメッド カンパニー, リミテッド 凍結乾燥dna製剤、組成物、及び凍結乾燥dna製剤を製造する方法
CA2853918C (en) * 2011-11-03 2020-12-29 Viromed Co., Ltd. Gene therapy for diabetic neuropathy using an hgf isoform
US10639351B2 (en) 2013-10-22 2020-05-05 Helixmith Co., Ltd. Method for treating amyotrophic lateral sclerosis with a polynucleotide encoding two or more isoforms of hepatocyte growth factor
CN103519900A (zh) * 2013-10-24 2014-01-22 河南科技大学第一附属医院 一种心胸外科护肺膜
KR101567954B1 (ko) * 2013-11-25 2015-11-11 인하대학교 산학협력단 Hgf 단백질 또는 그 유전자를 포함하는 발기부전 예방 또는 치료용 조성물 및 그의 용도
CN106536056B (zh) 2014-06-13 2021-07-16 儿童医学中心公司 分离线粒体的产品和方法
JP6532141B2 (ja) * 2014-09-26 2019-06-19 ヘリックスミス カンパニー リミテッド 肝細胞増殖因子及びストローマ細胞由来因子1αを用いた末梢動脈疾患の予防または治療用組成物
ES2761852T3 (es) 2015-01-21 2020-05-21 Centre Nat Rech Scient Proteínas agonistas del receptor MET
WO2017124037A1 (en) 2016-01-15 2017-07-20 The Children's Medical Center Corporation Therapeutic use of mitochondria and combined mitochondrial agents
WO2018167447A1 (en) * 2017-03-14 2018-09-20 University Of Sheffield Low dose aspirin (1-50 mg) together with antiplatelets such as ticagrelor of anticoagulants
CN109771642B (zh) 2017-11-13 2022-09-20 同济大学苏州研究院 c-MET激动型抗体及其用途
EP3823981A4 (en) 2018-07-17 2022-04-06 Neuromyon Inc. TREATMENT OF NEUROPATHY WITH DNA CONSTRUCTS EXPRESSING IGF-1 ISOFORMS
KR20210027493A (ko) 2018-07-19 2021-03-10 주식회사 헬릭스미스 네이키드 dna 유전자 요법을 위한 동결 건조된 약제학적 조성물
CA3130213A1 (en) 2019-02-15 2020-08-20 Children's Medical Center Corporation Treating heart failure

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US6673776B1 (en) * 1989-03-21 2004-01-06 Vical Incorporated Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
US5693622A (en) * 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
CA2022752C (en) * 1989-08-11 1998-07-07 Naomi Kitamura Hepatic parenchymal cell growth factor, gene encoding the same, process for producing the factor, and transformants producing the factor
US6706694B1 (en) * 1990-03-21 2004-03-16 Vical Incorporated Expression of exogenous polynucleotide sequences in a vertebrate
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US5830879A (en) * 1995-10-02 1998-11-03 St. Elizabeth's Medical Center Of Boston, Inc. Treatment of vascular injury using vascular endothelial growth factor
US6121246A (en) * 1995-10-20 2000-09-19 St. Elizabeth's Medical Center Of Boston, Inc. Method for treating ischemic tissue
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KR20000046969A (ko) 1998-12-31 2000-07-25 이선경 이종 유전자 유래의 유전자 발현 조절요소를 포함하는 강력한전사 활성을 가진 진핵세포 발현벡더
CN1182874C (zh) * 1999-10-29 2005-01-05 安增子摩祺株式会社 糖尿病性局部缺血疾病的基因治疗制剂
WO2002000258A1 (en) * 2000-06-27 2002-01-03 Anges Mg, Inc. Medicinal compositions for angiogenic therapy
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EP1234583A1 (en) * 2001-02-23 2002-08-28 F. Hoffmann-La Roche Ag PEG-conjugates of HGF-NK4
KR100562824B1 (ko) * 2002-03-20 2006-03-23 주식회사 바이로메드 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
JP2008537942A (ja) * 2005-03-31 2008-10-02 マイトジェン, インコーポレイテッド 心疾患のための処置
US20070212390A1 (en) * 2005-09-22 2007-09-13 Ludwig Institute For Cancer Research Protease-resistant forms of VEGF-D, method of making and method of use
CN101356189A (zh) * 2005-11-10 2009-01-28 受体生物公司 肝细胞生长因子内含子融合蛋白
JP5579164B2 (ja) * 2008-04-09 2014-08-27 ビロメッド カンパニー, リミテッド 凍結乾燥dna製剤、組成物、及び凍結乾燥dna製剤を製造する方法

Also Published As

Publication number Publication date
KR20100126316A (ko) 2010-12-01
EP2252321A4 (en) 2012-09-05
EP2252321B1 (en) 2015-04-29
WO2009093880A2 (en) 2009-07-30
DK2252321T3 (en) 2015-05-26
EP2252321A2 (en) 2010-11-24
PT2252321E (pt) 2015-07-07
ES2537971T3 (es) 2015-06-16
AU2009206869A1 (en) 2009-07-30
CA2712078C (en) 2015-02-24
CN101925362A (zh) 2010-12-22
CA2712078A1 (en) 2009-07-30
MX2010007887A (es) 2010-08-10
JP5563991B2 (ja) 2014-07-30
RU2448159C1 (ru) 2012-04-20
RU2010135532A (ru) 2012-02-27
AU2009206869B2 (en) 2012-04-19
JP2011510069A (ja) 2011-03-31
WO2009093880A3 (en) 2009-10-29
KR101325674B1 (ko) 2013-11-06
US20090202606A1 (en) 2009-08-13

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B25D Requested change of name of applicant approved

Owner name: HELIXMITH CO., LTD (KR)

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B25G Requested change of headquarter approved

Owner name: HELIXMITH CO., LTD (KR)

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]