BRPI0907624A2 - tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito - Google Patents
tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócitoInfo
- Publication number
- BRPI0907624A2 BRPI0907624A2 BRPI0907624A BRPI0907624A BRPI0907624A2 BR PI0907624 A2 BRPI0907624 A2 BR PI0907624A2 BR PI0907624 A BRPI0907624 A BR PI0907624A BR PI0907624 A BRPI0907624 A BR PI0907624A BR PI0907624 A2 BRPI0907624 A2 BR PI0907624A2
- Authority
- BR
- Brazil
- Prior art keywords
- prevention
- growth factor
- heart disease
- hepatocyte growth
- disease treatment
- Prior art date
Links
- 102000003745 Hepatocyte Growth Factor Human genes 0.000 title 1
- 108090000100 Hepatocyte Growth Factor Proteins 0.000 title 1
- 102000001708 Protein Isoforms Human genes 0.000 title 1
- 108010029485 Protein Isoforms Proteins 0.000 title 1
- 208000019622 heart disease Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2375608P | 2008-01-25 | 2008-01-25 | |
| PCT/KR2009/000406 WO2009093880A2 (en) | 2008-01-25 | 2009-01-28 | Treatment and prevention of cardiac conditions using two or more isoforms of hepatocyte growth factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0907624A2 true BRPI0907624A2 (pt) | 2016-08-16 |
Family
ID=40901564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0907624A BRPI0907624A2 (pt) | 2008-01-25 | 2009-01-28 | tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20090202606A1 (pt) |
| EP (1) | EP2252321B1 (pt) |
| JP (1) | JP5563991B2 (pt) |
| KR (1) | KR101325674B1 (pt) |
| CN (1) | CN101925362A (pt) |
| AU (1) | AU2009206869B2 (pt) |
| BR (1) | BRPI0907624A2 (pt) |
| CA (1) | CA2712078C (pt) |
| DK (1) | DK2252321T3 (pt) |
| ES (1) | ES2537971T3 (pt) |
| MX (1) | MX2010007887A (pt) |
| PT (1) | PT2252321E (pt) |
| RU (1) | RU2448159C1 (pt) |
| WO (1) | WO2009093880A2 (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8409214B2 (en) * | 2009-01-22 | 2013-04-02 | Meditech Development Incorporated | Portable regulated vacuum pump for medical procedures |
| KR100562824B1 (ko) | 2002-03-20 | 2006-03-23 | 주식회사 바이로메드 | 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자 |
| JP5579164B2 (ja) * | 2008-04-09 | 2014-08-27 | ビロメッド カンパニー, リミテッド | 凍結乾燥dna製剤、組成物、及び凍結乾燥dna製剤を製造する方法 |
| CA2853918C (en) * | 2011-11-03 | 2020-12-29 | Viromed Co., Ltd. | Gene therapy for diabetic neuropathy using an hgf isoform |
| US10639351B2 (en) | 2013-10-22 | 2020-05-05 | Helixmith Co., Ltd. | Method for treating amyotrophic lateral sclerosis with a polynucleotide encoding two or more isoforms of hepatocyte growth factor |
| CN103519900A (zh) * | 2013-10-24 | 2014-01-22 | 河南科技大学第一附属医院 | 一种心胸外科护肺膜 |
| KR101567954B1 (ko) * | 2013-11-25 | 2015-11-11 | 인하대학교 산학협력단 | Hgf 단백질 또는 그 유전자를 포함하는 발기부전 예방 또는 치료용 조성물 및 그의 용도 |
| CN106536056B (zh) | 2014-06-13 | 2021-07-16 | 儿童医学中心公司 | 分离线粒体的产品和方法 |
| JP6532141B2 (ja) * | 2014-09-26 | 2019-06-19 | ヘリックスミス カンパニー リミテッド | 肝細胞増殖因子及びストローマ細胞由来因子1αを用いた末梢動脈疾患の予防または治療用組成物 |
| ES2761852T3 (es) | 2015-01-21 | 2020-05-21 | Centre Nat Rech Scient | Proteínas agonistas del receptor MET |
| WO2017124037A1 (en) | 2016-01-15 | 2017-07-20 | The Children's Medical Center Corporation | Therapeutic use of mitochondria and combined mitochondrial agents |
| WO2018167447A1 (en) * | 2017-03-14 | 2018-09-20 | University Of Sheffield | Low dose aspirin (1-50 mg) together with antiplatelets such as ticagrelor of anticoagulants |
| CN109771642B (zh) | 2017-11-13 | 2022-09-20 | 同济大学苏州研究院 | c-MET激动型抗体及其用途 |
| EP3823981A4 (en) | 2018-07-17 | 2022-04-06 | Neuromyon Inc. | TREATMENT OF NEUROPATHY WITH DNA CONSTRUCTS EXPRESSING IGF-1 ISOFORMS |
| KR20210027493A (ko) | 2018-07-19 | 2021-03-10 | 주식회사 헬릭스미스 | 네이키드 dna 유전자 요법을 위한 동결 건조된 약제학적 조성물 |
| CA3130213A1 (en) | 2019-02-15 | 2020-08-20 | Children's Medical Center Corporation | Treating heart failure |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ232813A (en) * | 1989-03-10 | 1992-08-26 | Snow Brand Milk Products Co Ltd | Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons |
| US6673776B1 (en) * | 1989-03-21 | 2004-01-06 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human |
| US5693622A (en) * | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| CA2022752C (en) * | 1989-08-11 | 1998-07-07 | Naomi Kitamura | Hepatic parenchymal cell growth factor, gene encoding the same, process for producing the factor, and transformants producing the factor |
| US6706694B1 (en) * | 1990-03-21 | 2004-03-16 | Vical Incorporated | Expression of exogenous polynucleotide sequences in a vertebrate |
| DE69131069T2 (de) * | 1990-07-13 | 1999-07-15 | Snow Brand Milk Products Co., Ltd., Sapporo, Hokkaido | Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung |
| US5661133B1 (en) * | 1991-11-12 | 1999-06-01 | Univ Michigan | Collateral blood vessel formation in cardiac muscle by injecting a dna sequence encoding an angiogenic protein |
| US6498144B1 (en) * | 1993-10-18 | 2002-12-24 | North Shore - Long Island Jewish Research Institute | Use of scatter factor to enhance angiogenesis |
| US5837676A (en) * | 1993-10-18 | 1998-11-17 | Long Island Jewish Medical Center | Use of scatter factor to enhance angiogenesis |
| US5652225A (en) * | 1994-10-04 | 1997-07-29 | St. Elizabeth's Medical Center Of Boston, Inc. | Methods and products for nucleic acid delivery |
| US20030148968A1 (en) * | 1995-02-28 | 2003-08-07 | Hammond H. Kirk | Techniques and compositions for treating cardiovascular disease by in vivo gene delivery |
| CA2230819C (en) * | 1995-08-29 | 2009-04-14 | Sumitomo Pharmaceuticals Co., Ltd. | Medicament comprising hgf gene |
| US5830879A (en) * | 1995-10-02 | 1998-11-03 | St. Elizabeth's Medical Center Of Boston, Inc. | Treatment of vascular injury using vascular endothelial growth factor |
| US6121246A (en) * | 1995-10-20 | 2000-09-19 | St. Elizabeth's Medical Center Of Boston, Inc. | Method for treating ischemic tissue |
| JPH11246433A (ja) * | 1998-03-03 | 1999-09-14 | Sumitomo Pharmaceut Co Ltd | 心筋梗塞治療剤 |
| US20040228834A1 (en) * | 1998-03-09 | 2004-11-18 | Jeffrey Isner | Compositions and methods for modulating vascularization |
| CN1222310C (zh) * | 1998-08-05 | 2005-10-12 | 住友制药株式会社 | 肝实质细胞增殖因子药用制剂 |
| KR20000046969A (ko) | 1998-12-31 | 2000-07-25 | 이선경 | 이종 유전자 유래의 유전자 발현 조절요소를 포함하는 강력한전사 활성을 가진 진핵세포 발현벡더 |
| CN1182874C (zh) * | 1999-10-29 | 2005-01-05 | 安增子摩祺株式会社 | 糖尿病性局部缺血疾病的基因治疗制剂 |
| WO2002000258A1 (en) * | 2000-06-27 | 2002-01-03 | Anges Mg, Inc. | Medicinal compositions for angiogenic therapy |
| EP1361896A2 (en) * | 2001-01-23 | 2003-11-19 | Boston Scientific Corporation | Localized myocardial injection method for treating ischemic myocardium |
| EP1234583A1 (en) * | 2001-02-23 | 2002-08-28 | F. Hoffmann-La Roche Ag | PEG-conjugates of HGF-NK4 |
| KR100562824B1 (ko) * | 2002-03-20 | 2006-03-23 | 주식회사 바이로메드 | 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자 |
| JP2008537942A (ja) * | 2005-03-31 | 2008-10-02 | マイトジェン, インコーポレイテッド | 心疾患のための処置 |
| US20070212390A1 (en) * | 2005-09-22 | 2007-09-13 | Ludwig Institute For Cancer Research | Protease-resistant forms of VEGF-D, method of making and method of use |
| CN101356189A (zh) * | 2005-11-10 | 2009-01-28 | 受体生物公司 | 肝细胞生长因子内含子融合蛋白 |
| JP5579164B2 (ja) * | 2008-04-09 | 2014-08-27 | ビロメッド カンパニー, リミテッド | 凍結乾燥dna製剤、組成物、及び凍結乾燥dna製剤を製造する方法 |
-
2009
- 2009-01-23 US US12/359,137 patent/US20090202606A1/en not_active Abandoned
- 2009-01-28 DK DK09704660.1T patent/DK2252321T3/en active
- 2009-01-28 CA CA2712078A patent/CA2712078C/en not_active Expired - Fee Related
- 2009-01-28 MX MX2010007887A patent/MX2010007887A/es active IP Right Grant
- 2009-01-28 AU AU2009206869A patent/AU2009206869B2/en not_active Ceased
- 2009-01-28 RU RU2010135532/10A patent/RU2448159C1/ru not_active IP Right Cessation
- 2009-01-28 JP JP2010544236A patent/JP5563991B2/ja active Active
- 2009-01-28 PT PT97046601T patent/PT2252321E/pt unknown
- 2009-01-28 EP EP20090704660 patent/EP2252321B1/en active Active
- 2009-01-28 KR KR1020107018680A patent/KR101325674B1/ko active Active
- 2009-01-28 ES ES09704660.1T patent/ES2537971T3/es active Active
- 2009-01-28 BR BRPI0907624A patent/BRPI0907624A2/pt not_active Application Discontinuation
- 2009-01-28 CN CN2009801030779A patent/CN101925362A/zh active Pending
- 2009-01-28 WO PCT/KR2009/000406 patent/WO2009093880A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| KR20100126316A (ko) | 2010-12-01 |
| EP2252321A4 (en) | 2012-09-05 |
| EP2252321B1 (en) | 2015-04-29 |
| WO2009093880A2 (en) | 2009-07-30 |
| DK2252321T3 (en) | 2015-05-26 |
| EP2252321A2 (en) | 2010-11-24 |
| PT2252321E (pt) | 2015-07-07 |
| ES2537971T3 (es) | 2015-06-16 |
| AU2009206869A1 (en) | 2009-07-30 |
| CA2712078C (en) | 2015-02-24 |
| CN101925362A (zh) | 2010-12-22 |
| CA2712078A1 (en) | 2009-07-30 |
| MX2010007887A (es) | 2010-08-10 |
| JP5563991B2 (ja) | 2014-07-30 |
| RU2448159C1 (ru) | 2012-04-20 |
| RU2010135532A (ru) | 2012-02-27 |
| AU2009206869B2 (en) | 2012-04-19 |
| JP2011510069A (ja) | 2011-03-31 |
| WO2009093880A3 (en) | 2009-10-29 |
| KR101325674B1 (ko) | 2013-11-06 |
| US20090202606A1 (en) | 2009-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B25D | Requested change of name of applicant approved |
Owner name: HELIXMITH CO., LTD (KR) |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: HELIXMITH CO., LTD (KR) |
|
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |