BRPI0907624A2 - tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito - Google Patents

tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito

Info

Publication number
BRPI0907624A2
BRPI0907624A2 BRPI0907624A BRPI0907624A BRPI0907624A2 BR PI0907624 A2 BRPI0907624 A2 BR PI0907624A2 BR PI0907624 A BRPI0907624 A BR PI0907624A BR PI0907624 A BRPI0907624 A BR PI0907624A BR PI0907624 A2 BRPI0907624 A2 BR PI0907624A2
Authority
BR
Brazil
Prior art keywords
prevention
growth factor
heart disease
hepatocyte growth
disease treatment
Prior art date
Application number
BRPI0907624A
Other languages
English (en)
Inventor
Jong-Mook Kim
Sujeong Kim
Woong Hahn
Original Assignee
Viromed Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viromed Co Ltd filed Critical Viromed Co Ltd
Publication of BRPI0907624A2 publication Critical patent/BRPI0907624A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1833Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
BRPI0907624A 2008-01-25 2009-01-28 tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito BRPI0907624A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2375608P 2008-01-25 2008-01-25
PCT/KR2009/000406 WO2009093880A2 (en) 2008-01-25 2009-01-28 Treatment and prevention of cardiac conditions using two or more isoforms of hepatocyte growth factor

Publications (1)

Publication Number Publication Date
BRPI0907624A2 true BRPI0907624A2 (pt) 2016-08-16

Family

ID=40901564

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0907624A BRPI0907624A2 (pt) 2008-01-25 2009-01-28 tratamento e prevenção de doenças cardíacas usando duas ou mais isoformas do fator de crescimento de hepatócito

Country Status (14)

Country Link
US (1) US20090202606A1 (pt)
EP (1) EP2252321B1 (pt)
JP (1) JP5563991B2 (pt)
KR (1) KR101325674B1 (pt)
CN (1) CN101925362A (pt)
AU (1) AU2009206869B2 (pt)
BR (1) BRPI0907624A2 (pt)
CA (1) CA2712078C (pt)
DK (1) DK2252321T3 (pt)
ES (1) ES2537971T3 (pt)
MX (1) MX2010007887A (pt)
PT (1) PT2252321E (pt)
RU (1) RU2448159C1 (pt)
WO (1) WO2009093880A2 (pt)

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ES2556711T3 (es) * 2008-04-09 2016-01-19 Viromed Co., Ltd. Formulaciones liofilizadas de ADN para el aumento de la expresión del ADN plasmídico
AU2012333408B2 (en) * 2011-11-03 2016-05-26 Viromed Co., Ltd. Gene therapy for diabetic neuropathy using an HGF isoform
AU2014337870B2 (en) 2013-10-22 2019-11-28 Helixmith Co., Ltd. Composition for preventing or treating amyotrophic lateral sclerosis using two or more isoforms of hepatocyte growth factor
CN103519900A (zh) * 2013-10-24 2014-01-22 河南科技大学第一附属医院 一种心胸外科护肺膜
KR101567954B1 (ko) * 2013-11-25 2015-11-11 인하대학교 산학협력단 Hgf 단백질 또는 그 유전자를 포함하는 발기부전 예방 또는 치료용 조성물 및 그의 용도
CA2952121A1 (en) 2014-06-13 2015-12-17 Childrens' Medical Center Corporation Products and methods to isolate mitochondria
KR101756131B1 (ko) * 2014-09-26 2017-07-12 주식회사 바이로메드 간세포 성장인자 및 기질세포 유발인자1알파를 이용한 말초동맥질환의 예방 또는 치료용 조성물
US10435450B2 (en) 2015-01-21 2019-10-08 Centre National De La Recherche Scientifique MET receptor agonist proteins
DK4272834T3 (da) 2016-01-15 2025-12-15 Childrens Medical Ct Corp Terapeutisk anvendelse af mitokondrier og kombinerede mitokondrielle midler
WO2018167447A1 (en) * 2017-03-14 2018-09-20 University Of Sheffield Low dose aspirin (1-50 mg) together with antiplatelets such as ticagrelor of anticoagulants
CN109771642B (zh) 2017-11-13 2022-09-20 同济大学苏州研究院 c-MET激动型抗体及其用途
CA3106078A1 (en) 2018-07-17 2020-01-23 Junghun Lee Treatment of neuropathy with dna constructs expressing igf-1 isoforms
US11554179B2 (en) 2018-07-19 2023-01-17 Helixmith Co., Ltd Lyophilized pharmaceutical compositions for naked DNA gene therapy
EP3923963A4 (en) 2019-02-15 2022-11-23 Children's Medical Center Corporation TREATMENT OF HEART FAILURE

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US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5693622A (en) * 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US6673776B1 (en) * 1989-03-21 2004-01-06 Vical Incorporated Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird or human
CA2022752C (en) * 1989-08-11 1998-07-07 Naomi Kitamura Hepatic parenchymal cell growth factor, gene encoding the same, process for producing the factor, and transformants producing the factor
US6706694B1 (en) * 1990-03-21 2004-03-16 Vical Incorporated Expression of exogenous polynucleotide sequences in a vertebrate
JP2634323B2 (ja) * 1990-07-13 1997-07-23 雪印乳業株式会社 Tcf‐▲ii▼のアミノ酸配列をコードするdnaを含むプラスミド,形質転換細胞及びこれを用いて生理活性物質を生産する方法
US5661133B1 (en) * 1991-11-12 1999-06-01 Univ Michigan Collateral blood vessel formation in cardiac muscle by injecting a dna sequence encoding an angiogenic protein
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US5837676A (en) * 1993-10-18 1998-11-17 Long Island Jewish Medical Center Use of scatter factor to enhance angiogenesis
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US20030148968A1 (en) * 1995-02-28 2003-08-07 Hammond H. Kirk Techniques and compositions for treating cardiovascular disease by in vivo gene delivery
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US5830879A (en) * 1995-10-02 1998-11-03 St. Elizabeth's Medical Center Of Boston, Inc. Treatment of vascular injury using vascular endothelial growth factor
US6121246A (en) * 1995-10-20 2000-09-19 St. Elizabeth's Medical Center Of Boston, Inc. Method for treating ischemic tissue
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ES2313907T3 (es) * 1999-10-29 2009-03-16 Anges Mg, Inc. Terapia genica para la isquemia diabetica.
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EP1234583A1 (en) * 2001-02-23 2002-08-28 F. Hoffmann-La Roche Ag PEG-conjugates of HGF-NK4
KR100562824B1 (ko) * 2002-03-20 2006-03-23 주식회사 바이로메드 유전자 발현효율이 높으며 간세포 성장인자의 두 가지이형체를 동시에 발현하는 하이브리드 간세포 성장인자유전자
WO2006121532A2 (en) * 2005-03-31 2006-11-16 Mytogen, Inc. Treatment for heart disease
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ES2556711T3 (es) * 2008-04-09 2016-01-19 Viromed Co., Ltd. Formulaciones liofilizadas de ADN para el aumento de la expresión del ADN plasmídico

Also Published As

Publication number Publication date
AU2009206869A1 (en) 2009-07-30
DK2252321T3 (en) 2015-05-26
CN101925362A (zh) 2010-12-22
JP2011510069A (ja) 2011-03-31
EP2252321A4 (en) 2012-09-05
RU2448159C1 (ru) 2012-04-20
CA2712078C (en) 2015-02-24
WO2009093880A3 (en) 2009-10-29
EP2252321A2 (en) 2010-11-24
KR101325674B1 (ko) 2013-11-06
RU2010135532A (ru) 2012-02-27
EP2252321B1 (en) 2015-04-29
WO2009093880A2 (en) 2009-07-30
MX2010007887A (es) 2010-08-10
AU2009206869B2 (en) 2012-04-19
ES2537971T3 (es) 2015-06-16
KR20100126316A (ko) 2010-12-01
US20090202606A1 (en) 2009-08-13
PT2252321E (pt) 2015-07-07
CA2712078A1 (en) 2009-07-30
JP5563991B2 (ja) 2014-07-30

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B25D Requested change of name of applicant approved

Owner name: HELIXMITH CO., LTD (KR)

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B25G Requested change of headquarter approved

Owner name: HELIXMITH CO., LTD (KR)

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]