BRPI0908194A2 - método para a profilaxia ou o tratamento de restenose, composição farmacêutica, stent de eluição de droga, e, método para fabricar um stent - Google Patents

método para a profilaxia ou o tratamento de restenose, composição farmacêutica, stent de eluição de droga, e, método para fabricar um stent

Info

Publication number: BRPI0908194A2
Authority: BR; Brazil
Prior art keywords: stent; restenosis; prophylaxis; manufacturing; treatment
Prior art date: 2008-02-22

Application number

BRPI0908194A

Other languages

English (en)

Inventor

Johan Frostegard

Knut Pettersson

Ola Camber

Original Assignee

Athera Biotechnologies Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-02-22

Filing date

2009-02-20

Publication date

2016-07-05

2009-02-20 Application filed by Athera Biotechnologies Ab filed Critical Athera Biotechnologies Ab

2016-07-05 Publication of BRPI0908194A2 publication Critical patent/BRPI0908194A2/pt

2022-01-04 Publication of BRPI0908194B1 publication Critical patent/BRPI0908194B1/pt

2023-03-28 Publication of BRPI0908194B8 publication Critical patent/BRPI0908194B8/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3625—Vascular tissue, e.g. heart valves
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Dermatology (AREA)
Surgery (AREA)
Transplantation (AREA)
Oral & Maxillofacial Surgery (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Botany (AREA)
Materials Engineering (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Rheumatology (AREA)

BRPI0908194A 2008-02-22 2009-02-20 Uso de uma anexina a5 recombinante, e stent de eluição de fármaco BRPI0908194B8 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US3080308P	2008-02-22	2008-02-22
US61/030,803		2008-02-22
PCT/GB2009/000454 WO2009103977A1 (en)	2008-02-22	2009-02-20	Compounds and methods for the prevention or treatment of restenosis

Publications (3)

Publication Number	Publication Date
BRPI0908194A2 true BRPI0908194A2 (pt)	2016-07-05
BRPI0908194B1 BRPI0908194B1 (pt)	2022-01-04
BRPI0908194B8 BRPI0908194B8 (pt)	2023-03-28

Family

ID=40723470

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0908194A BRPI0908194B8 (pt)	2008-02-22	2009-02-20	Uso de uma anexina a5 recombinante, e stent de eluição de fármaco

Country Status (15)

Country	Link
US (3)	US9295716B2 (pt)
EP (2)	EP3216457B1 (pt)
JP (4)	JP2011512393A (pt)
KR (1)	KR101692392B1 (pt)
CN (1)	CN101969978A (pt)
AU (1)	AU2009216543B2 (pt)
BR (1)	BRPI0908194B8 (pt)
CA (1)	CA2715859C (pt)
DK (2)	DK3216457T3 (pt)
ES (2)	ES2733902T3 (pt)
HU (2)	HUE044621T2 (pt)
MX (1)	MX2010009270A (pt)
PL (2)	PL2254589T3 (pt)
TR (1)	TR201909412T4 (pt)
WO (1)	WO2009103977A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2740557C (en) *	2008-10-17	2020-04-14	London Health Sciences Centre Research Inc.	Annexin and its use to treat inflammatory disorders
WO2010069605A2 (en)	2008-12-19	2010-06-24	Medirista Biotechnologies Ab	Oxidized cardiolipin as a novel pro-inflammatory factor
WO2011160845A2 (en)	2010-06-24	2011-12-29	Medirista Biotechnologies Ab	Oxidized phospholipids and lipoproteins, and antibodies thereto, as biomarkers of inflammatory conditions and methods of treatment
DK2694538T3 (da) *	2011-04-05	2017-01-02	Annexin Pharmaceuticals Ab	Terapeutiske og profylaktiske fremgangsmåder, anvendelser og sammensætninger omfattende anexin a5
GB201322777D0 (en) *	2013-12-20	2014-02-05	Algipharma As	Use of alginate oligomers as blood anticoagulants
GB2542391A (en)	2015-09-17	2017-03-22	Annexin Pharmaceuticals Ab	Process of manufacture
GB201702144D0 (en)	2017-02-09	2017-03-29	Annexin Pharmaceuticals Ab	Therapeutic compositions
CN111388152B (zh) *	2018-12-27	2021-12-03	元心科技(深圳)有限公司	药物洗脱器械及其制备方法
CN111494608A (zh) *	2020-05-08	2020-08-07	北京大学第三医院（北京大学第三临床医学院）	预防或治疗子痫前期及相关病症的药物及其应用
CN113317879B (zh) *	2021-05-28	2022-06-07	郑州大学第一附属医院	一种预测肝硬化患者tips术后支架再狭窄的试剂盒
CN117897399A (zh)	2021-06-14	2024-04-16	Inserm(法国国家健康医学研究院)	突变的膜联蛋白a5多肽及其在治疗目的中的用途
KR102823180B1 (ko) *	2022-09-08	2025-06-20	건국대학교 글로컬산학협력단	Annexin A5를 코팅하고 항원을 탑재한 나노입자 및 이의 용도

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US5545208A (en) *	1990-02-28	1996-08-13	Medtronic, Inc.	Intralumenal drug eluting prosthesis
US5122154A (en) *	1990-08-15	1992-06-16	Rhodes Valentine J	Endovascular bypass graft
US6602281B1 (en)	1995-06-05	2003-08-05	Avantec Vascular Corporation	Radially expansible vessel scaffold having beams and expansion joints
US5922020A (en)	1996-08-02	1999-07-13	Localmed, Inc.	Tubular prosthesis having improved expansion and imaging characteristics
AU2001237805A1 (en) *	2000-02-08	2001-08-20	Acspurt B.V.	Material and method for immobilization of bioactive species
US6602282B1 (en)	2000-05-04	2003-08-05	Avantec Vascular Corporation	Flexible stent structure
US20050222030A1 (en)	2001-02-21	2005-10-06	Anthony Allison	Modified annexin proteins and methods for preventing thrombosis
US7645739B2 (en)	2001-02-21	2010-01-12	Alavita Pharmaceuticals, Inc.	Modified annexin compositions and methods of using same
US7635680B2 (en) *	2001-02-21	2009-12-22	Alavita Pharmaceuticals, Inc.	Attenuation of reperfusion injury
EP1379266B1 (en)	2001-02-21	2007-04-18	SurroMed, Inc.	Modified annexin proteins and prevention and treatment of thrombosis
JP4444821B2 (ja) *	2002-06-06	2010-03-31	ツェ・チェイン・ウン	遺伝子組み換えによる新しい抗凝血性蛋白質
MXPA05005925A (es) *	2002-12-02	2006-02-08	Abgenix Inc	Anticuerpos dirigidos a la fosfolipasa a2 y sus usos.
US20050037052A1 (en)	2003-08-13	2005-02-17	Medtronic Vascular, Inc.	Stent coating with gradient porosity
US20060083772A1 (en)	2004-04-06	2006-04-20	Dewitt David M	Coating compositions for bioactive agents
PT1755642E (pt) *	2004-04-15	2010-04-20	Athera Biotechnologies Ab	Anexina v para prevenção de aterotrombose e da ruptura de placas
PL2234631T3 (pl) *	2007-12-18	2013-03-29	Athera Biotechnologies Ab	Związki i metody stosowane w terapii choroby naczyniowej
CN103262479B (zh) *	2010-12-17	2016-08-10	日本电气株式会社	通信系统、节点、分组转发方法

2009
- 2009-02-20 HU HUE17152300 patent/HUE044621T2/hu unknown
- 2009-02-20 PL PL09713277T patent/PL2254589T3/pl unknown
- 2009-02-20 CA CA2715859A patent/CA2715859C/en active Active
- 2009-02-20 CN CN2009801058346A patent/CN101969978A/zh active Pending
- 2009-02-20 ES ES17152300T patent/ES2733902T3/es active Active
- 2009-02-20 WO PCT/GB2009/000454 patent/WO2009103977A1/en not_active Ceased
- 2009-02-20 PL PL17152300T patent/PL3216457T3/pl unknown
- 2009-02-20 EP EP17152300.4A patent/EP3216457B1/en active Active
- 2009-02-20 TR TR2019/09412T patent/TR201909412T4/tr unknown
- 2009-02-20 AU AU2009216543A patent/AU2009216543B2/en not_active Ceased
- 2009-02-20 HU HUE09713277A patent/HUE035034T2/en unknown
- 2009-02-20 JP JP2010547244A patent/JP2011512393A/ja active Pending
- 2009-02-20 DK DK17152300.4T patent/DK3216457T3/da active
- 2009-02-20 EP EP09713277.3A patent/EP2254589B1/en active Active
- 2009-02-20 MX MX2010009270A patent/MX2010009270A/es active IP Right Grant
- 2009-02-20 US US12/918,709 patent/US9295716B2/en active Active
- 2009-02-20 KR KR1020107021145A patent/KR101692392B1/ko not_active Expired - Fee Related
- 2009-02-20 ES ES09713277.3T patent/ES2630013T3/es active Active
- 2009-02-20 BR BRPI0908194A patent/BRPI0908194B8/pt not_active IP Right Cessation
- 2009-02-20 DK DK09713277.3T patent/DK2254589T3/en active
2014
- 2014-08-07 JP JP2014161098A patent/JP5964369B2/ja not_active Expired - Fee Related
2016
- 2016-03-01 US US15/058,068 patent/US9901614B2/en active Active
- 2016-06-29 JP JP2016128598A patent/JP2016175946A/ja active Pending
2018
- 2018-01-11 US US15/868,256 patent/US20180140668A1/en not_active Abandoned
2019
- 2019-03-05 JP JP2019039719A patent/JP6889193B2/ja active Active

Also Published As

Publication number	Publication date
EP3216457B1 (en)	2019-04-10
JP2016175946A (ja)	2016-10-06
US9901614B2 (en)	2018-02-27
EP3216457A1 (en)	2017-09-13
US20180140668A1 (en)	2018-05-24
MX2010009270A (es)	2010-09-24
AU2009216543A1 (en)	2009-08-27
CA2715859C (en)	2021-07-20
ES2630013T3 (es)	2017-08-17
DK2254589T3 (en)	2017-07-10
AU2009216543B2 (en)	2014-07-24
JP2015007074A (ja)	2015-01-15
DK3216457T3 (da)	2019-07-15
KR20100122501A (ko)	2010-11-22
BRPI0908194B8 (pt)	2023-03-28
PL3216457T3 (pl)	2019-09-30
EP2254589A1 (en)	2010-12-01
US20160250284A1 (en)	2016-09-01
JP2011512393A (ja)	2011-04-21
KR101692392B1 (ko)	2017-01-03
JP6889193B2 (ja)	2021-06-18
HUE044621T2 (hu)	2019-11-28
JP5964369B2 (ja)	2016-08-03
TR201909412T4 (tr)	2019-07-22
CA2715859A1 (en)	2009-08-27
EP2254589B1 (en)	2017-04-05
JP2019081805A (ja)	2019-05-30
CN101969978A (zh)	2011-02-09
ES2733902T3 (es)	2019-12-03
HUE035034T2 (en)	2018-05-02
PL2254589T3 (pl)	2017-11-30
BRPI0908194B1 (pt)	2022-01-04
WO2009103977A1 (en)	2009-08-27
US20100331970A1 (en)	2010-12-30
US9295716B2 (en)	2016-03-29

Legal Events

Date	Code	Title	Description
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-10-15	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2019-10-29	B06U	Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
2021-06-01	B350	Update of information on the portal [chapter 15.35 patent gazette]
2021-07-27	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2021-11-09	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2022-01-04	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/02/2009, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.
2023-03-07	B25A	Requested transfer of rights approved	Owner name: MEDIRISTA AB (SE)
2023-03-28	B25A	Requested transfer of rights approved	Owner name: ANNEXIN PHARMACEUTICALS AB (SE)
2025-02-04	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 16A ANUIDADE.
2025-06-17	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2822 DE 04-02-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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