BRPI0908361A2 - Seringas previamente cheias contendo composição e métodos de preparação das mesmas e de estabilização de agente de ligação específico em composição. - Google Patents

Seringas previamente cheias contendo composição e métodos de preparação das mesmas e de estabilização de agente de ligação específico em composição.

Info

Publication number
BRPI0908361A2
BRPI0908361A2 BRPI0908361A BRPI0908361A2 BR PI0908361 A2 BRPI0908361 A2 BR PI0908361A2 BR PI0908361 A BRPI0908361 A BR PI0908361A BR PI0908361 A2 BRPI0908361 A2 BR PI0908361A2
Authority
BR
Brazil
Prior art keywords
composition
preparing
methods
binding agent
specific binding
Prior art date
Application number
Other languages
English (en)
Inventor
Roberta Bonk
Mingda Eu
Amy Huinker
Monica Pallitto
Margaret Ricci
Nicole Stackhouse
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of BRPI0908361A2 publication Critical patent/BRPI0908361A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
BRPI0908361 2008-02-07 2009-02-05 Seringas previamente cheias contendo composição e métodos de preparação das mesmas e de estabilização de agente de ligação específico em composição. BRPI0908361A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6506508P 2008-02-07 2008-02-07
PCT/US2009/000759 WO2009099641A2 (en) 2008-02-07 2009-02-05 Stabilized protein compositions

Publications (1)

Publication Number Publication Date
BRPI0908361A2 true BRPI0908361A2 (pt) 2015-04-07

Family

ID=40532483

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908361 BRPI0908361A2 (pt) 2008-02-07 2009-02-05 Seringas previamente cheias contendo composição e métodos de preparação das mesmas e de estabilização de agente de ligação específico em composição.

Country Status (14)

Country Link
US (1) US20110060290A1 (pt)
EP (1) EP2249801A2 (pt)
JP (2) JP2011519347A (pt)
KR (1) KR20100138908A (pt)
CN (2) CN103720587A (pt)
AU (1) AU2009210741A1 (pt)
BR (1) BRPI0908361A2 (pt)
CA (1) CA2714006A1 (pt)
EA (1) EA201001223A1 (pt)
IL (1) IL207340A0 (pt)
MX (1) MX2010008696A (pt)
SG (1) SG10201402265YA (pt)
WO (1) WO2009099641A2 (pt)
ZA (2) ZA201005779B (pt)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006138181A2 (en) 2005-06-14 2006-12-28 Amgen Inc. Self-buffering protein formulations
WO2010100135A1 (en) 2009-03-05 2010-09-10 Ablynx N.V. Novel antigen binding dimer-complexes, methods of making/avoiding and uses thereof
US9265834B2 (en) 2009-03-05 2016-02-23 Ablynx N.V. Stable formulations of polypeptides and uses thereof
LT2805731T (lt) 2009-09-03 2019-02-11 Ablynx N.V. Stabilios polipeptidų kompozicijos ir jų panaudojimas
TWI907924B (zh) * 2011-05-02 2025-12-11 日商武田藥品工業股份有限公司 抗-α4β7抗體之調配物
PT3858405T (pt) 2012-06-01 2023-06-26 Novartis Ag Seringa
DE202013000688U1 (de) 2012-07-03 2013-03-05 Novartis Ag Glas-Spritze
JP6271536B2 (ja) 2012-07-09 2018-01-31 コヒラス・バイオサイエンシズ・インコーポレイテッド 肉眼不可視粒子の著しい低減を示すエタネルセプト製剤
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
WO2015006444A1 (en) * 2013-07-10 2015-01-15 Merit Medical Systems, Inc. Pre-loaded syringes and methods related thereto
RU2702748C2 (ru) * 2014-05-12 2019-10-11 Формикон Аг Предварительно заполненный пластиковый шприц, содержащий антагонист vegf
EP3191576A4 (en) * 2014-09-12 2018-04-18 Anthrogenesis Corporation Methods for quantifying particulates in cell culture
WO2016051962A1 (ja) * 2014-10-02 2016-04-07 テルモ株式会社 タンパク質溶液製剤を収容するための医療用容器
BR112017008658A2 (pt) * 2014-10-30 2017-12-19 Hoffmann La Roche seringa e método de preparação da mesma
HUE052280T2 (hu) * 2014-12-03 2021-04-28 Csl Behring Ag Immunoglobulinokat tartalmazó megnövelt stabilitású gyógyszerészeti termék
US11229702B1 (en) 2015-10-28 2022-01-25 Coherus Biosciences, Inc. High concentration formulations of adalimumab
WO2018218013A2 (en) 2017-05-24 2018-11-29 Sio2 Medical Products, Inc. Sterilizable pharmaceutical package for ophthalmic formulations
AU2016356717B2 (en) 2015-11-18 2022-09-29 Sio2 Medical Products, Inc. Pharmaceutical package for ophthalmic formulations
WO2017085253A1 (en) * 2015-11-18 2017-05-26 Formycon Ag Pre-filled plastic syringe containing a vegf antagonist
RU2734958C2 (ru) 2015-11-18 2020-10-26 Формикон Аг Предварительно заполненная фармацевтическая упаковка, содержащая жидкий состав на основе антагониста vegf
US11472878B2 (en) * 2016-04-15 2022-10-18 The Board Of Trustees Of The Leland Stanford Junior University Methods for determining and achieving therapeutically effective doses of anti-CD47 agents in treatment of cancer
WO2017184880A1 (en) 2016-04-20 2017-10-26 Coherus Biosciences, Inc. A method of filling a container with no headspace
WO2017188267A1 (ja) * 2016-04-25 2017-11-02 テルモ株式会社 プレフィルドシリンジ用のシリンジ本体、シリンジシステム及びプレフィルドシリンジ
CA3036356A1 (en) * 2016-09-09 2018-03-15 Cutispharma, Inc. Suspensions and diluents for metronidazole and baclofen
ES3064802T3 (en) * 2016-10-21 2026-04-29 Amgen Inc Pharmaceutical formulations and methods of making the same
EP3370040B1 (de) 2017-03-02 2021-04-21 Fresenius Kabi Austria GmbH Verfahren zur bestimmung eines gasvolumens einer fertigspritze und verwendung des verfahrens zur eichung einer anlage zum abfüllen einer fertigspritze
HRP20240167T1 (hr) 2017-04-28 2024-04-26 Amgen Inc. Formulacije ljudskih anti-rankl protutijela i postupci njihove upotrebe
RU2019138507A (ru) 2017-05-02 2021-06-02 Мерк Шарп И Доум Корп. Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
EP3630043A1 (en) 2017-05-24 2020-04-08 Formycon AG Sterilizable pre-filled pharmaceutical packages comprising a liquid formulation of a vegf-antagonist
JP6635454B1 (ja) * 2019-04-16 2020-01-22 株式会社Ｋｏｒｔｕｃ シリコーンオイル（を含有するオイル組成物）により優れた過酸化水素保存性を示す過酸化水素溶液プレフィルドガラス製シリンジ
CA3095165A1 (en) 2018-03-27 2019-10-03 Sio2 Medical Products, Inc. Vessels, containers, and surfaces coated with water barrier coatings
CN113056482A (zh) 2018-10-18 2021-06-29 默沙东公司 抗rsv抗体的制剂及其使用方法
JP2019048091A (ja) * 2018-10-23 2019-03-28 ニプロ株式会社 デクスメデトミジン注射液を充填したプレフィルドシリンジ
CN120842406A (zh) 2018-10-31 2025-10-28 默沙东有限责任公司 抗人pd-1抗体晶体及其使用方法
KR20210089215A (ko) 2018-11-07 2021-07-15 머크 샤프 앤드 돔 코포레이션 항-lag3 항체 및 항-pd-1 항체의 공동-제제
AU2019378874B2 (en) * 2018-11-14 2025-05-29 Avm Biotechnology, Llc Stable glucocorticoid formulation
KR20210079373A (ko) * 2018-11-16 2021-06-29 삼성바이오에피스 주식회사 단백질을 포함하는 안정한 액상 조성물
CN109821076B (zh) * 2019-03-13 2021-05-07 陕西师范大学 一种抗凝抗感染的多功能涂层的制备方法及抗凝抗感染的多功能材料
DK3960702T3 (da) * 2019-03-29 2023-08-07 Kortuc Inc Anvendelse af en oliesammensætning omfattende silikoneolie til stabilisering af opbevaring af hydrogenperoxid
EP4098238A4 (en) * 2020-01-28 2024-02-28 Zeon Corporation PREFILLED MEDICINAL PACKAGING AND METHOD FOR PRODUCING A PREFILLED MEDICINAL PACKAGING
WO2022059766A1 (en) 2020-09-18 2022-03-24 Chugai Seiyaku Kabushiki Kaisha Anti-hla-dq2.5 antibody and its use for the treatment of celiac disease
CN117120125A (zh) * 2021-03-30 2023-11-24 肖特制药瑞士股份公司 用于低温储存药物组合物的系统、液体组合物、方法和用途
WO2022207655A1 (en) * 2021-03-30 2022-10-06 Schott Schweiz Ag System for low-temperature storage of a pharmaceutical composition, liquid composition, method and uses
AU2022285895A1 (en) * 2021-06-03 2023-12-14 Becton Dickinson France Method of making a low-silicone oil system for a medical injection device
MX2024004117A (es) * 2021-10-08 2024-04-19 Chugai Pharmaceutical Co Ltd Metodo para preparar formulacion de jeringa precargada.
KR102614250B1 (ko) * 2021-10-08 2023-12-15 추가이 세이야쿠 가부시키가이샤 항hla-dq2.5 항체의 제제
JP2025529049A (ja) * 2022-08-30 2025-09-04 アムジエン・インコーポレーテツド シリンジ内の肉眼不可視粒子を制限するシステム及び方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652763A (en) * 1985-03-29 1987-03-24 Energy Sciences, Inc. Electron-beam irradiation sterilization process
US6551576B1 (en) * 1989-12-22 2003-04-22 Bristol-Myers Squibb Medical Imaging, Inc. Container with multi-phase composition for use in diagnostic and therapeutic applications
US6146657A (en) * 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
US5773024A (en) * 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5519984A (en) * 1995-03-16 1996-05-28 Mallinckrodt Medical, Inc. Methods for packaging a pressure or vacuum sensitive product
JP3329219B2 (ja) * 1997-02-05 2002-09-30 スズキ株式会社 船外機の電装部品設置構造
DK1029548T3 (da) * 1997-10-15 2007-07-02 Asahi Kasei Pharma Corp Fremgangsmåde til opretholdelse af kvaliteten af vandige, parenterale oplösninger af thrombomodulin under lagring og transport
US6274169B1 (en) * 1999-08-02 2001-08-14 Abbott Laboratories Low oxygen content compostions of 1α, 25-dihydroxycholecalciferol
EP1232753B1 (en) * 1999-09-08 2008-03-19 Chugai Seiyaku Kabushiki Kaisha Stable protein solution filled in a container made from a hydrophobic resin and method of stabilizing the same
US6595961B2 (en) * 2001-04-16 2003-07-22 Becton, Dickinson And Company Sterilizable transfer or storage device for medicaments, drugs and vaccines
CA2451955C (en) * 2001-06-26 2015-09-29 Abgenix, Inc. Antibodies to opgl
US20030104996A1 (en) * 2001-08-30 2003-06-05 Tiansheng Li L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
SI1478394T1 (sl) * 2002-02-27 2008-12-31 Immunex Corp STABILIZIRAN TNFR-Fc SESTAVEK Z ARGININOM
RU2364609C2 (ru) * 2003-05-23 2009-08-20 Ново Нордиск Хелт Кэр Аг Стабилизация белка в растворе
JP2007521315A (ja) * 2003-08-01 2007-08-02 アムジェン インコーポレイテッド 結晶性腫瘍壊死因子レセプター２ポリペプチド

Also Published As

Publication number Publication date
MX2010008696A (es) 2010-08-30
ZA201005779B (en) 2014-12-23
SG10201402265YA (en) 2014-08-28
CN103720587A (zh) 2014-04-16
US20110060290A1 (en) 2011-03-10
WO2009099641A2 (en) 2009-08-13
WO2009099641A3 (en) 2011-02-24
EP2249801A2 (en) 2010-11-17
IL207340A0 (en) 2010-12-30
CA2714006A1 (en) 2009-08-13
EA201001223A1 (ru) 2011-06-30
AU2009210741A1 (en) 2009-08-13
JP2011519347A (ja) 2011-07-07
KR20100138908A (ko) 2010-12-31
JP2015042638A (ja) 2015-03-05
CN102202643A (zh) 2011-09-28
ZA201109364B (en) 2015-11-25

Similar Documents

Publication Publication Date Title
FIC20240036I1 (fi) Geeniterapia, joka ilmentää ihmisen hyytymistekijä IX:n muunnosta R338L
IL264316B1 (en) Stable liquid formulations containing anti-il-1beta antibody, syringes and self-injection syringes containing them
IL216550A (en) Immunomodulatory agent-polymeric compounds, compositions comprising them, methods for their production and their uses
BRPI0819361A2 (pt) Composição de tratamento de cabelos e agente de tratamento
BRPI0920030A2 (pt) agente de oclusão do tecido
IL221372A0 (en) 6 -benzylphenyl- 2 - sulfurterahydropyran-3, 4, 5 -triol derivatives as inhibitors of sodium -glucose cotrans porters 1 and 2 for use in diabetic patients
EP2120959A4 (en) METHOD AND COMPOSITIONS FOR TREATING INSULIN RESISTANCE, DIABETES AND DIABETES-BASED DYSLIPIDEMIA
BR112013013414A2 (pt) dispositivos de coleta de sangue contendo agente de estabilização de sangue
BR112014023937A2 (pt) composição farmacêutica, agente farmacêutico de combinação e método de tratamento
BRPI0811270A2 (pt) Alimento de baixo teor de gordura, e, agente de intensificação de sabor
BRPI0816948A2 (pt) Composição fungicida para controlar fungos nocivos fitopatogênicos, agente fungicida, método para controlar fungos nocivos fitopatogênicos, semente, e, uso dos componentes
ZA201305498B (en) Methods and compositions suitable for managing blood glucose in animals
BR112015000527A2 (pt) agente reológico, métodos de preparação e usos dos mesmos.
BR112013015796A2 (pt) composição de agente de formação de imagem, método de preparar uma composição de agente de formação de imagem, método de preparar um quelante 18f-nota, e, composição farmacêutica.
BRPI1011188A2 (pt) composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas.
BRPI0910760A2 (pt) método para remineralizar tecido, agente remineralizador, e, kit
EP2879686A4 (en) COMPOSITIONS AND METHODS FOR REDUCING THE BLOOD ALCOHOLIC STRENGTH
BRPI0821720A2 (pt) Aplicação de líquidos iônicos, magnéticos como agente de extração
HU0800434D0 (en) Template to determine the places of the injections, especially for regular medicament injection and/or blood testing
BRPI0819719A8 (pt) compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo
BR112013015798A2 (pt) composição de agente de formação de imagem, método de preparar uma composição de agente de formação de imagem, e, composição farmacêutica
DK2407474T3 (da) Triacetyl-3-hydroxyfenyladenosin og dets anvendelse til regulering af blodfedt
BRPI0915527A2 (pt) pepitídeos, composição farmacêutica e exossomos compreendendo os mesmos, métodos e usos
DK2352493T3 (da) Terapeutisk, diætetisk eller kosmetisk anvendelse af forbindelser med specifik antiapoptotisk aktivitet mod caspase-3 og sammensætninger, der indeholder disse forbindelser
GB201108964D0 (en) Medicament and method of diagnosis

Legal Events

Date Code Title Description
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: COM BASE NA RESOLUCAO 228/09, SOLICITA-SE QUE SEJAM APRESENTADOS NOVOS CD S/DVD S, POIS O ARQUIVO DE LISTAGEM DE SEQUENCIA NAO FOI APRESENTADO NO FORMATO TXT E SOLICITA-SE A APRESENTACAO DE DECLARACAO IMPRESSA E ASSINADA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2364 DE 26-04-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.