BRPI0908428A2 - uso de ranozalina para tratar a dor. - Google Patents

uso de ranozalina para tratar a dor.

Info

Publication number
BRPI0908428A2
BRPI0908428A2 BRPI0908428A BRPI0908428A BRPI0908428A2 BR PI0908428 A2 BRPI0908428 A2 BR PI0908428A2 BR PI0908428 A BRPI0908428 A BR PI0908428A BR PI0908428 A BRPI0908428 A BR PI0908428A BR PI0908428 A2 BRPI0908428 A2 BR PI0908428A2
Authority
BR
Brazil
Prior art keywords
ranozaline
treat pain
pain
treat
Prior art date
Application number
BRPI0908428A
Other languages
English (en)
Inventor
Ivan Diamond
John Shryock
Luiz Belardinelli
Sridharan Rajamani
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of BRPI0908428A2 publication Critical patent/BRPI0908428A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0908428A 2008-02-06 2009-02-06 uso de ranozalina para tratar a dor. BRPI0908428A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2669908P 2008-02-06 2008-02-06
US5743708P 2008-05-30 2008-05-30
PCT/US2009/033464 WO2009100380A1 (en) 2008-02-06 2009-02-06 Use of ranolazine for treating pain

Publications (1)

Publication Number Publication Date
BRPI0908428A2 true BRPI0908428A2 (pt) 2015-12-08

Family

ID=40548472

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0908428A BRPI0908428A2 (pt) 2008-02-06 2009-02-06 uso de ranozalina para tratar a dor.

Country Status (13)

Country Link
US (1) US20090203707A1 (pt)
EP (1) EP2252294A1 (pt)
KR (1) KR20110013348A (pt)
CN (1) CN101977605A (pt)
AU (1) AU2009212254A1 (pt)
BR (1) BRPI0908428A2 (pt)
CA (1) CA2713521A1 (pt)
CO (1) CO6290663A2 (pt)
EA (1) EA201070914A1 (pt)
EC (1) ECSP10010446A (pt)
IL (1) IL207292A0 (pt)
MA (1) MA32132B1 (pt)
WO (1) WO2009100380A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
MXPA04011530A (es) * 2002-05-21 2005-08-15 Cv Therapeutics Inc Administracion de un inhibidor de acido graso parcial tal como ranolazina para el tratamiento de diabetes.
US20090247535A1 (en) * 2008-03-26 2009-10-01 Duke University Use of ranolazine for non-cardiovascular disorders
JP2012526848A (ja) * 2009-05-14 2012-11-01 ギリアード サイエンシーズ， インコーポレイテッド Ｃｎｓ障害の治療のためのラノラジン
US8952034B2 (en) 2009-07-27 2015-02-10 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
BR112012033402A2 (pt) 2010-07-02 2017-01-24 Gilead Sciences Inc moduladores de canais de íons conforme os compostos heterocíclicos fundidos
CA2834164A1 (en) 2011-05-10 2012-11-15 Gilead Sciences, Inc. Fused benzoxazinones as ion channel modulators
NO3175985T3 (pt) 2011-07-01 2018-04-28
TW201837023A (zh) 2011-07-01 2018-10-16 美商基利科學股份有限公司 作為離子通道調節劑之稠合雜環化合物
AU2014364783B2 (en) 2013-12-19 2017-01-05 Gilead Sciences, Inc. Fused heterocyclic compounds as ion channel modulators
AU2017228371A1 (en) 2016-03-04 2018-09-13 Gilead Sciences, Inc. Compositions and combinations of autotaxin inhibitors
US11261188B2 (en) 2016-11-28 2022-03-01 Praxis Precision Medicines, Inc. Fused heteroaryl compounds, and methods thereof for treating diseases, disorders, and conditions relating to aberrant function of a sodium channel
DK3548033T3 (da) 2016-11-28 2024-07-15 Praxis Prec Medicines Inc Forbindelser og deres fremgangsmåde til anvendelse
US11492345B2 (en) 2017-02-13 2022-11-08 Praxis Precision Medicines, Inc. Compounds and their methods of use
WO2018187480A1 (en) 2017-04-04 2018-10-11 Praxis Precision Medicines, Inc. Compounds and their methods of use
WO2019035951A1 (en) 2017-08-15 2019-02-21 Praxis Precision Medicines, Inc. COMPOUNDS AND THEIR METHODS OF USE
WO2019232209A1 (en) 2018-05-30 2019-12-05 Praxis Precision Medicines, Inc. Ion channel modulators
EA202092908A1 (ru) 2018-09-28 2021-05-14 Праксис Пресижн Медсинз, Инк. Модуляторы ионных каналов
US11773099B2 (en) 2019-05-28 2023-10-03 Praxis Precision Medicines, Inc. Compounds and their methods of use
US11505554B2 (en) 2019-05-31 2022-11-22 Praxis Precision Medicines, Inc. Substituted pyridines as ion channel modulators
US11279700B2 (en) 2019-05-31 2022-03-22 Praxis Precision Medicines, Inc. Ion channel modulators
EP4065124A4 (en) 2019-11-26 2023-12-06 Praxis Precision Medicines, Inc. ION CHANNEL MODULATORS
US12552797B2 (en) 2019-11-27 2026-02-17 Praxis Precision Medicines, Inc. Process for making (3-[cyclopropylethoxy(difluoro)methyl]-6-6[5-fluoro-6-(2,2,2-trifluoroethoxy-3-pyridyl]- [1,2,4]triazolo[4,3-a]pyrazine
US12533341B2 (en) 2019-12-11 2026-01-27 Duke University Small molecule inhibitors of voltage-gated sodium channel 1.7 and methods of using same
MX2024013240A (es) 2022-04-26 2024-12-06 Praxis Prec Medicines Inc Tratamiento de trastornos neurologicos
WO2025252860A1 (en) * 2024-06-04 2025-12-11 Celex Oncology Innovations Limited Ranolazine enantiomer for use in cancer treatment

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657264A (en) * 1985-11-01 1987-04-14 Ingersoll-Rand Company Fluid seal assembly with segmented sub-assembly
ATE142497T1 (de) * 1989-06-23 1996-09-15 Syntex Inc Ranolazin und verwandte piperazine zur behandlung von geweben, von physischen oder chemischen schäden betroffen
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
US6479496B1 (en) * 1998-09-10 2002-11-12 Cv Therapeutics, Inc. Methods for treating angina with ranolazine
US6303607B1 (en) * 1998-09-10 2001-10-16 Cv Therapeutics, Inc. Method for administering a sustained release ranolanolazine formulation
JP2004505886A (ja) * 2000-02-18 2004-02-26 スィーヴィー　セラピューティクス　インコーポレイテッド 鬱血性心不全の処置における部分的な脂肪酸酸化阻害剤
US20030220344A1 (en) * 2002-04-04 2003-11-27 Luiz Belardinelli Method of treating arrhythmias
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
MXPA04011530A (es) * 2002-05-21 2005-08-15 Cv Therapeutics Inc Administracion de un inhibidor de acido graso parcial tal como ranolazina para el tratamiento de diabetes.
CA2593593A1 (en) * 2005-01-06 2006-07-13 Cv Therapeutics, Inc. Sustained release pharmaceutical formulations comprising ranolazine
JP2009516751A (ja) * 2005-11-21 2009-04-23 ザ・ボード・オブ・トラスティーズ・オブ・ザ・ユニバーシティー・オブ・アラバマ・フォー・アンド・オン・ビハーフ・オブ・ザ・ユニバーシティー・オブ・アラバマ 神経保護のための小分子化合物を使用する方法
EP2046769A2 (en) * 2006-07-27 2009-04-15 Cv Therapeutics, Inc. Aldh-2 inhibitors in the treatment of addiction
CA2678319A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of coronary microvascular diseases
EP2117509A1 (en) * 2007-02-13 2009-11-18 CV Therapeutics Inc. Use of ranolazine for the treatment of cardiovascular diseases
JP2010523590A (ja) * 2007-04-05 2010-07-15 ギリアード・パロ・アルト・インコーポレイテッド Ａｌｄｈ−２阻害剤としてのキナゾリノン誘導体
EP2139480A1 (en) * 2007-04-12 2010-01-06 CV Therapeutics Inc. Ranolazine for enhancing insulin secretion
US20090124672A1 (en) * 2007-11-06 2009-05-14 Ivan Diamond Aldh-2 inhibitors in the treatment of psychiatric disorders

Also Published As

Publication number Publication date
CN101977605A (zh) 2011-02-16
IL207292A0 (en) 2010-12-30
CO6290663A2 (es) 2011-06-20
KR20110013348A (ko) 2011-02-09
AU2009212254A1 (en) 2009-08-13
CA2713521A1 (en) 2009-08-13
WO2009100380A1 (en) 2009-08-13
MA32132B1 (fr) 2011-03-01
EA201070914A1 (ru) 2011-04-29
EP2252294A1 (en) 2010-11-24
US20090203707A1 (en) 2009-08-13
ECSP10010446A (es) 2010-10-30

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]