BRPI0908577A2 - preparação farmacêutica estável por longo tempo com a substância ativa trinitrato de glicerol - Google Patents
preparação farmacêutica estável por longo tempo com a substância ativa trinitrato de glicerolInfo
- Publication number
- BRPI0908577A2 BRPI0908577A2 BRPI0908577A BRPI0908577A BRPI0908577A2 BR PI0908577 A2 BRPI0908577 A2 BR PI0908577A2 BR PI0908577 A BRPI0908577 A BR PI0908577A BR PI0908577 A BRPI0908577 A BR PI0908577A BR PI0908577 A2 BRPI0908577 A2 BR PI0908577A2
- Authority
- BR
- Brazil
- Prior art keywords
- active substance
- pharmaceutical preparation
- stable long
- term pharmaceutical
- glycerol trinitrate
- Prior art date
Links
- SNIOPGDIGTZGOP-UHFFFAOYSA-N Nitroglycerin Chemical compound [O-][N+](=O)OCC(O[N+]([O-])=O)CO[N+]([O-])=O SNIOPGDIGTZGOP-UHFFFAOYSA-N 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 230000007774 longterm Effects 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4826408A | 2008-03-14 | 2008-03-14 | |
| PCT/EP2009/001772 WO2009112258A1 (de) | 2008-03-14 | 2009-03-12 | Langzeitstabile pharmazeutische zubereitung mit dem wirkstoff glyceroltrinitrat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0908577A2 true BRPI0908577A2 (pt) | 2017-05-16 |
Family
ID=39670662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0908577A BRPI0908577A2 (pt) | 2008-03-14 | 2009-03-12 | preparação farmacêutica estável por longo tempo com a substância ativa trinitrato de glicerol |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2254552B1 (pt) |
| AU (1) | AU2009224968B2 (pt) |
| BR (1) | BRPI0908577A2 (pt) |
| CA (1) | CA2718345C (pt) |
| DE (1) | DE202008007318U1 (pt) |
| IL (1) | IL208151A0 (pt) |
| RU (1) | RU2010142023A (pt) |
| WO (1) | WO2009112258A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100184870A1 (en) | 2008-03-14 | 2010-07-22 | Rolf Groteluschen | Long-term stable pharmaceutical preparation containing the active ingredient glycerol trinitrate |
| EP2990032A1 (en) * | 2010-08-03 | 2016-03-02 | G. Pohl-Boskamp GmbH & Co. KG | Use of glyceryl trinitrate for treating traumatic edema |
| EP2678000B1 (en) | 2011-02-25 | 2018-03-07 | G. Pohl-Boskamp GmbH & Co. KG | Stabilized granules containing glyceryl trinitrate |
| ES2617494T3 (es) | 2012-05-31 | 2017-06-19 | G. Pohl-Boskamp Gmbh & Co. Kg | Inducción de arteriogénesis con un donador de óxido nítrico tal como nitroglicerina |
| US9248099B2 (en) | 2012-05-31 | 2016-02-02 | Desmoid Aktiengesellschaft | Use of stabilized granules containing glyceryl trinitrate for arteriogenesis |
| EP2878310B1 (en) | 2013-11-29 | 2017-01-11 | G. Pohl-Boskamp GmbH & Co. KG | Sprayable aqueous composition comprising glyceryl trinitrate |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE632504A (pt) | 1962-05-24 | |||
| JPS599539B2 (ja) * | 1979-11-13 | 1984-03-03 | 日本化薬株式会社 | ニトログリセリン水溶液及びその製造法 |
| CA1163195A (en) * | 1980-06-26 | 1984-03-06 | Alec D. Keith | Polymeric diffusion matrix containing a vasodilator |
| DE3246081A1 (de) | 1982-12-13 | 1984-06-14 | G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt | Nitroglycerin-spray |
| DE4007705C1 (pt) | 1990-03-10 | 1991-09-26 | G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De | |
| US5370862A (en) * | 1990-06-13 | 1994-12-06 | Schwarz Pharma Ag | Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina |
| DE4018919C2 (de) | 1990-06-13 | 1994-08-25 | Sanol Arznei Schwarz Gmbh | Nitroglycerin-Spray |
| DE4026072A1 (de) | 1990-08-17 | 1992-02-20 | Sanol Arznei Schwarz Gmbh | Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray |
| US5698589A (en) * | 1993-06-01 | 1997-12-16 | International Medical Innovations, Inc. | Water-based topical cream containing nitroglycerin and method of preparation and use thereof |
| US5869082A (en) | 1996-04-12 | 1999-02-09 | Flemington Pharmaceutical Corp. | Buccal, non-polar spray for nitroglycerin |
| WO1999038472A2 (en) * | 1998-01-28 | 1999-08-05 | Seatrace Pharmaceuticals Inc | Topical vasodilatory gel composition and methods of use and production |
| US20070059346A1 (en) * | 2003-07-01 | 2007-03-15 | Todd Maibach | Film comprising therapeutic agents |
-
2008
- 2008-05-30 DE DE202008007318U patent/DE202008007318U1/de not_active Expired - Lifetime
-
2009
- 2009-03-12 WO PCT/EP2009/001772 patent/WO2009112258A1/de not_active Ceased
- 2009-03-12 AU AU2009224968A patent/AU2009224968B2/en active Active
- 2009-03-12 RU RU2010142023/15A patent/RU2010142023A/ru not_active Application Discontinuation
- 2009-03-12 CA CA2718345A patent/CA2718345C/en active Active
- 2009-03-12 BR BRPI0908577A patent/BRPI0908577A2/pt not_active IP Right Cessation
- 2009-03-12 EP EP09720940.7A patent/EP2254552B1/de active Active
-
2010
- 2010-09-14 IL IL208151A patent/IL208151A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE202008007318U1 (de) | 2008-07-31 |
| EP2254552A1 (de) | 2010-12-01 |
| CA2718345C (en) | 2015-07-07 |
| CA2718345A1 (en) | 2009-09-17 |
| WO2009112258A1 (de) | 2009-09-17 |
| IL208151A0 (en) | 2010-12-30 |
| RU2010142023A (ru) | 2012-04-20 |
| AU2009224968A1 (en) | 2009-09-17 |
| EP2254552B1 (de) | 2016-08-24 |
| AU2009224968B2 (en) | 2014-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |