BRPI0909189A2 - combinações sinergísticas de 5'-metiltioadenosina - Google Patents
combinações sinergísticas de 5'-metiltioadenosinaInfo
- Publication number
- BRPI0909189A2 BRPI0909189A2 BRPI0909189A BRPI0909189A BRPI0909189A2 BR PI0909189 A2 BRPI0909189 A2 BR PI0909189A2 BR PI0909189 A BRPI0909189 A BR PI0909189A BR PI0909189 A BRPI0909189 A BR PI0909189A BR PI0909189 A2 BRPI0909189 A2 BR PI0909189A2
- Authority
- BR
- Brazil
- Prior art keywords
- methylthioadenosine
- synergistic combinations
- synergistic
- combinations
- Prior art date
Links
- WUUGFSXJNOTRMR-IOSLPCCCSA-N 5'-S-methyl-5'-thioadenosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CSC)O[C@H]1N1C2=NC=NC(N)=C2N=C1 WUUGFSXJNOTRMR-IOSLPCCCSA-N 0.000 title 1
- 239000011885 synergistic combination Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200800806A ES2329327B1 (es) | 2008-03-19 | 2008-03-19 | Combinaciones sinergicas de 5'-metiltioadenosina. |
| PCT/ES2009/070067 WO2009115634A1 (es) | 2008-03-19 | 2009-03-18 | Combinaciones sinérgicas de 5'-metiltioadenosina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0909189A2 true BRPI0909189A2 (pt) | 2016-08-02 |
Family
ID=40785496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0909189A BRPI0909189A2 (pt) | 2008-03-19 | 2009-03-18 | combinações sinergísticas de 5'-metiltioadenosina |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8236778B2 (pt) |
| EP (1) | EP2281566A1 (pt) |
| JP (1) | JP2011515377A (pt) |
| CN (1) | CN101977613A (pt) |
| AU (1) | AU2009227068A1 (pt) |
| BR (1) | BRPI0909189A2 (pt) |
| CA (1) | CA2717419A1 (pt) |
| ES (1) | ES2329327B1 (pt) |
| MX (1) | MX2010010094A (pt) |
| RU (1) | RU2010142456A (pt) |
| WO (1) | WO2009115634A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010142827A1 (es) * | 2009-06-11 | 2010-12-16 | Proyecto De Biomedicina Cima, S. L. | Propiedades neuroprotectoras de 5'-metiltioadenosina |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| US20130035390A1 (en) * | 2010-01-13 | 2013-02-07 | Ramot At Tel-Aviv University Ltd. | Treatment of multiple sclerosis |
| IN2014MN00333A (pt) * | 2011-07-28 | 2015-09-25 | Teva Pharma | |
| JP2014530821A (ja) * | 2011-10-12 | 2014-11-20 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドおよびフィンゴリモドを組み合わせた多発性硬化症の治療 |
| EP2609914A1 (en) * | 2011-12-29 | 2013-07-03 | Universitätsklinikum Hamburg-Eppendorf | Novel methods for treating or preventing neurodegeneration |
| WO2013116657A1 (en) | 2012-02-03 | 2013-08-08 | Teva Pharmaceutical Industries Ltd. | USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY |
| UY34896A (es) * | 2012-07-12 | 2014-02-28 | Teva Pharma | Tratamiento de la esclerosis múltiple con una combinación de laquinimod y fampridina |
| US20160193276A1 (en) * | 2012-12-21 | 2016-07-07 | Teva Pharmaceutical Industries, Ltd. | Transmucosal delivery of glatiramer acetate |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| AU2017319728B2 (en) | 2016-08-31 | 2024-09-05 | Mapi Pharma Ltd | Depot systems comprising glatiramer acetate |
| MX2019010174A (es) | 2017-03-26 | 2019-10-15 | Mapi Pharma Ltd | Sistemas de deposito de glatiramer para el tratamiento de formas progresivas de esclerosis multiple. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1227049B (it) | 1988-07-29 | 1991-03-14 | Bioresearch Spa | Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante. |
| HUP0001186A3 (en) | 1996-10-16 | 2002-04-29 | Icn Pharmaceuticals Inc Costa | Purine l-nucleosides,analogs and pharmaceutical compositions thereof |
| AU2868699A (en) * | 1998-02-13 | 1999-08-30 | Autoimmune, Inc. | Treatment of multiple sclerosis using cop-1 and th2-enhancing cytokines |
| JP2007500693A (ja) | 2003-07-31 | 2007-01-18 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 移植片拒絶反応を予防するための合成ペプチドコポリマーを含む併用療法 |
| HRP20090646T1 (hr) | 2005-03-17 | 2010-01-31 | Proyecto De Biomedicina Cima | Uporaba 5'-metiltioadenozina (mta) kod prevencije i/ili liječenja autoimunih bolesti i/ili odbacivanje transplantata |
-
2008
- 2008-03-19 ES ES200800806A patent/ES2329327B1/es not_active Withdrawn - After Issue
-
2009
- 2009-03-18 BR BRPI0909189A patent/BRPI0909189A2/pt not_active IP Right Cessation
- 2009-03-18 MX MX2010010094A patent/MX2010010094A/es active IP Right Grant
- 2009-03-18 EP EP09722096A patent/EP2281566A1/en not_active Withdrawn
- 2009-03-18 CA CA2717419A patent/CA2717419A1/en not_active Abandoned
- 2009-03-18 RU RU2010142456/15A patent/RU2010142456A/ru not_active Application Discontinuation
- 2009-03-18 AU AU2009227068A patent/AU2009227068A1/en not_active Withdrawn
- 2009-03-18 WO PCT/ES2009/070067 patent/WO2009115634A1/es not_active Ceased
- 2009-03-18 US US12/922,980 patent/US8236778B2/en not_active Expired - Fee Related
- 2009-03-18 CN CN200980109743XA patent/CN101977613A/zh active Pending
- 2009-03-18 JP JP2011500244A patent/JP2011515377A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CN101977613A (zh) | 2011-02-16 |
| US20110015132A1 (en) | 2011-01-20 |
| WO2009115634A1 (es) | 2009-09-24 |
| MX2010010094A (es) | 2010-11-12 |
| JP2011515377A (ja) | 2011-05-19 |
| US8236778B2 (en) | 2012-08-07 |
| RU2010142456A (ru) | 2012-04-27 |
| ES2329327B1 (es) | 2010-09-17 |
| AU2009227068A1 (en) | 2009-09-24 |
| EP2281566A1 (en) | 2011-02-09 |
| ES2329327A1 (es) | 2009-11-24 |
| CA2717419A1 (en) | 2009-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |