BRPI0909189A2 - combinações sinergísticas de 5'-metiltioadenosina - Google Patents

combinações sinergísticas de 5'-metiltioadenosina

Info

Publication number
BRPI0909189A2
BRPI0909189A2 BRPI0909189A BRPI0909189A BRPI0909189A2 BR PI0909189 A2 BRPI0909189 A2 BR PI0909189A2 BR PI0909189 A BRPI0909189 A BR PI0909189A BR PI0909189 A BRPI0909189 A BR PI0909189A BR PI0909189 A2 BRPI0909189 A2 BR PI0909189A2
Authority
BR
Brazil
Prior art keywords
methylthioadenosine
synergistic combinations
synergistic
combinations
Prior art date
Application number
BRPI0909189A
Other languages
English (en)
Inventor
Beatriz Moreno Bruna
Begoña Fernández Díez
Fernando José Corrales Izquierdo
Matias Antonio Ávila Zaragozá
Pablo Villoslada Díaz
Original Assignee
Proyecto Biomedicina Cima Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proyecto Biomedicina Cima Sl filed Critical Proyecto Biomedicina Cima Sl
Publication of BRPI0909189A2 publication Critical patent/BRPI0909189A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0909189A 2008-03-19 2009-03-18 combinações sinergísticas de 5'-metiltioadenosina BRPI0909189A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200800806A ES2329327B1 (es) 2008-03-19 2008-03-19 Combinaciones sinergicas de 5'-metiltioadenosina.
PCT/ES2009/070067 WO2009115634A1 (es) 2008-03-19 2009-03-18 Combinaciones sinérgicas de 5'-metiltioadenosina

Publications (1)

Publication Number Publication Date
BRPI0909189A2 true BRPI0909189A2 (pt) 2016-08-02

Family

ID=40785496

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909189A BRPI0909189A2 (pt) 2008-03-19 2009-03-18 combinações sinergísticas de 5'-metiltioadenosina

Country Status (11)

Country Link
US (1) US8236778B2 (pt)
EP (1) EP2281566A1 (pt)
JP (1) JP2011515377A (pt)
CN (1) CN101977613A (pt)
AU (1) AU2009227068A1 (pt)
BR (1) BRPI0909189A2 (pt)
CA (1) CA2717419A1 (pt)
ES (1) ES2329327B1 (pt)
MX (1) MX2010010094A (pt)
RU (1) RU2010142456A (pt)
WO (1) WO2009115634A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2441459A1 (en) * 2009-06-11 2012-04-18 Proyecto de Biomedicina Cima, S.L. 5'-methylthioadenosine neuroprotective properties
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
WO2011086470A1 (en) * 2010-01-13 2011-07-21 Ramot At Tel-Aviv University Ltd Treatment of multiple sclerosis
CN103781354A (zh) * 2011-07-28 2014-05-07 泰华制药工业有限公司 用拉喹莫德与醋酸格拉替雷的组合治疗多发性硬化症
EP2766020A4 (en) * 2011-10-12 2015-04-01 Teva Pharma TREATMENT OF MULTIPLE SCLEROSIS BY COMBINING LAQUINIMOD AND FINGOLIMOD
EP2609914A1 (en) * 2011-12-29 2013-07-03 Universitätsklinikum Hamburg-Eppendorf Novel methods for treating or preventing neurodegeneration
AR089862A1 (es) 2012-02-03 2014-09-24 Teva Pharma USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA
UY34896A (es) * 2012-07-12 2014-02-28 Teva Pharma Tratamiento de la esclerosis múltiple con una combinación de laquinimod y fampridina
AU2013361053A1 (en) * 2012-12-21 2015-07-30 Teva Pharmaceutical Industries Ltd. Transmucosal delivery of glatiramer acetate
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
CN109982712A (zh) 2016-08-31 2019-07-05 Mapi医药公司 包含醋酸格拉替雷的储库系统
BR112019017724A2 (pt) 2017-03-26 2020-03-31 Mapi Pharma Ltd. Sistemas depot de glatiramer para tratar formas progressivas de esclerose múltipla

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1227049B (it) 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
DE69729887T2 (de) 1996-10-16 2005-07-28 ICN Pharmaceuticals, Inc., Costa Mesa Purin-L-Nukleoside, Analoga und deren Verwendung
AU2868699A (en) * 1998-02-13 1999-08-30 Autoimmune, Inc. Treatment of multiple sclerosis using cop-1 and th2-enhancing cytokines
US20060276390A1 (en) 2003-07-31 2006-12-07 Yeda Research And Development Co. Ltd. Combined treatments comprising synthetic peptide copolymers for preventing graft rejection
US7820637B2 (en) 2005-03-17 2010-10-26 Proyecto De Biomedicina Cima, S.L. Use of 5′-methylthioadenosine (MTA) in the prevention and/or treatment of autoimmune diseases and/or transplant rejection

Also Published As

Publication number Publication date
US8236778B2 (en) 2012-08-07
MX2010010094A (es) 2010-11-12
JP2011515377A (ja) 2011-05-19
CN101977613A (zh) 2011-02-16
AU2009227068A1 (en) 2009-09-24
WO2009115634A1 (es) 2009-09-24
ES2329327B1 (es) 2010-09-17
CA2717419A1 (en) 2009-09-24
EP2281566A1 (en) 2011-02-09
US20110015132A1 (en) 2011-01-20
ES2329327A1 (es) 2009-11-24
RU2010142456A (ru) 2012-04-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.