BRPI0814876A2 - Análogos de pirona fosforilados e métodos - Google Patents
Análogos de pirona fosforilados e métodosInfo
- Publication number
- BRPI0814876A2 BRPI0814876A2 BRPI0814876-7A2A BRPI0814876A BRPI0814876A2 BR PI0814876 A2 BRPI0814876 A2 BR PI0814876A2 BR PI0814876 A BRPI0814876 A BR PI0814876A BR PI0814876 A2 BRPI0814876 A2 BR PI0814876A2
- Authority
- BR
- Brazil
- Prior art keywords
- pyrona
- phosphorilated
- analogs
- methods
- pyrona analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95318807P | 2007-07-31 | 2007-07-31 | |
| US7660808P | 2008-06-27 | 2008-06-27 | |
| PCT/US2008/071588 WO2009018338A2 (en) | 2007-07-31 | 2008-07-30 | Phosphorylated pyrone analogs and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0814876A2 true BRPI0814876A2 (pt) | 2014-09-30 |
Family
ID=40305253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0814876-7A2A BRPI0814876A2 (pt) | 2007-07-31 | 2008-07-30 | Análogos de pirona fosforilados e métodos |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7947733B2 (pt) |
| EP (1) | EP2182957A4 (pt) |
| JP (1) | JP2011500512A (pt) |
| KR (1) | KR20100051829A (pt) |
| CN (1) | CN101969959A (pt) |
| AU (1) | AU2008282261A1 (pt) |
| BR (1) | BRPI0814876A2 (pt) |
| CA (1) | CA2693338A1 (pt) |
| GB (1) | GB2464645B (pt) |
| MX (1) | MX2010001141A (pt) |
| TW (1) | TW200924785A (pt) |
| WO (1) | WO2009018338A2 (pt) |
| ZA (1) | ZA201001390B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009018350A1 (en) * | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Pyrone analog compositions and methods |
| JP2011500512A (ja) | 2007-07-31 | 2011-01-06 | リメリック バイオファーマ,インコーポレイティド | リン酸化ピロン類似体および方法 |
| CN102438614A (zh) * | 2008-10-10 | 2012-05-02 | 利默里克生物制药公司 | 用于治疗的吡喃酮类似物 |
| EP2424541A2 (en) * | 2009-04-27 | 2012-03-07 | Limerick BioPharma, Inc. | Phosphorylated and phosphonated pyrone analogs for therapeutic treatment |
| CN102946881A (zh) | 2010-04-23 | 2013-02-27 | 奇尼塔公司 | 抗病毒化合物 |
| WO2012068539A1 (en) * | 2010-11-19 | 2012-05-24 | Limerick Biopharma, Inc. | Use and composition of quercetin-3'-o-sulfate for therapeutic treatment |
| CN103491965A (zh) | 2011-02-25 | 2014-01-01 | 奇尼塔公司 | 识别rig-i通路调节因子的方法和细胞 |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| CN104530127B (zh) * | 2014-12-12 | 2016-09-14 | 广东东阳光药业有限公司 | 一种淫羊藿苷衍生物及其使用方法和用途 |
| CN106632479B (zh) * | 2016-12-22 | 2018-10-23 | 贵州大学 | O,o’-二烷基-o”-(取代黄酮-3-基)磷酸酯类衍生物、制备方法及应用 |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| US10881634B2 (en) * | 2017-12-07 | 2021-01-05 | Hughes Biotechnology Co., Ltd | Method for treatment or prevention of a disease associated with a decrease in bone mass and method of improving bone architecture and bio mechanical strength of bone |
| US12377112B2 (en) | 2019-04-17 | 2025-08-05 | Compass Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
Family Cites Families (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR837588A (fr) | 1938-03-25 | 1939-02-14 | Perfectionnements aux chaînes ou garnitures anti-patinantes et anti-dérapantes pour roues de véhicules | |
| US2764596A (en) | 1952-07-01 | 1956-09-25 | Nat Drug Co | Inorganic acid esters of polyhydroxylated flavones and flavanones |
| US4530844A (en) | 1984-07-26 | 1985-07-23 | Warner-Lambert Company | Synergistic non-steroidal anti-inflammatory compounds and compositions thereof |
| JPH01153695A (ja) * | 1987-12-11 | 1989-06-15 | Showa Denko Kk | ルチンまたはケルセチンリン酸エステルの製造法 |
| JPH01308476A (ja) | 1988-06-06 | 1989-12-13 | Showa Denko Kk | 紫外線吸収剤 |
| US6007840A (en) | 1988-09-16 | 1999-12-28 | Novartis Ag | Pharmaceutical compositions comprising cyclosporins |
| US5342625A (en) | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
| KR0148748B1 (ko) | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| US5643901A (en) | 1990-06-11 | 1997-07-01 | Fujisawa Pharmaceutical Co., Ltd. | Medicament for treating idiopathic thrombocytopenic purpura |
| US5348966A (en) | 1990-10-24 | 1994-09-20 | Fujisawa Pharmaceutical Co., Ltd. | Method for treating pyoderma and Sezary's syndrome using FK 506 and related compounds |
| US5817333A (en) | 1991-10-31 | 1998-10-06 | Fujisawa Pharmaceutical Co., Ltd. | Liposome preparation containing a tricyclic compound |
| JPH07509442A (ja) | 1991-11-18 | 1995-10-19 | メレルダウファーマスーティカルズ インコーポレイテッド | ウィルス病処置でのホスホリル化フラボノイド類 |
| JPH072826A (ja) | 1992-03-12 | 1995-01-06 | Sanwa Kagaku Kenkyusho Co Ltd | フラボン誘導体 |
| US5972598A (en) | 1992-09-17 | 1999-10-26 | Board Of Trustess Of The University Of Illinois | Methods for preventing multidrug resistance in cancer cells |
| JPH06345646A (ja) | 1993-06-08 | 1994-12-20 | Fujisawa Pharmaceut Co Ltd | ローション剤 |
| US6362160B1 (en) | 1993-06-30 | 2002-03-26 | The Johns Hopkins University School Of Medicine | Immunophilin-binding agents prevent glutamate neurotoxicity associated with vascular stroke and neurodegenerative diseases |
| US6022852A (en) | 1993-10-22 | 2000-02-08 | Hexal Ag | Pharmaceutical composition containing cyclosporin A |
| AU4515996A (en) | 1995-01-09 | 1996-07-31 | Alpha-Therapeutics, Inc. | Methods for increasing the bioavailability of biological active agents |
| DE69734060T2 (de) | 1996-05-24 | 2006-06-29 | Angiotech Pharmaceuticals, Inc., Vancouver | Zubereitungen und verfahren zur behandlung oder prävention von krankheiten der körperpassagewege |
| GB9613455D0 (en) * | 1996-06-27 | 1996-08-28 | Aston Molecules Ltd | Analogues or derivatives of quercetin |
| US6673768B1 (en) | 1997-10-16 | 2004-01-06 | Board Of Regents, The University Of Texas System | Transgenic animal models for cardiac hypertrophy and methods of use thereof (treating) |
| US6013621A (en) | 1997-10-17 | 2000-01-11 | The Rockfeller University | Method of treating psychosis and/or hyperactivity |
| CN1283991A (zh) | 1997-12-03 | 2001-02-14 | 藤泽药品工业株式会社 | 软质颗粒状药剂以及它的制造方法 |
| PT1056454E (pt) | 1998-02-23 | 2003-08-29 | Fujisawa Pharmaceutical Co | Utilizacao de compostos macrolido para o tratamento do glaucoma |
| AUPP223198A0 (en) | 1998-03-06 | 1998-04-02 | Fujisawa Pharmaceutical Co., Ltd. | New use |
| US6458777B1 (en) | 1998-03-13 | 2002-10-01 | Mucosal Therapeutics Llc | Methods and compositions for treating and preventing mucositis |
| ME00189B (me) | 1998-03-26 | 2011-02-10 | Astellas Pharma Inc | Preparati sa neprekidnim oslobađanjem |
| JP2002509555A (ja) | 1998-04-06 | 2002-03-26 | 藤沢薬品工業株式会社 | 新規用途 |
| GB9814640D0 (en) | 1998-07-06 | 1998-09-02 | Fujisawa Pharmaceutical Co | New use |
| AUPP584198A0 (en) | 1998-09-14 | 1998-10-08 | Fujisawa Pharmaceutical Co., Ltd. | New use |
| EP1135157A4 (en) | 1998-10-19 | 2004-12-08 | Univ New York | METHOD FOR REGULATING THE PERMEABILITY OF THE HEMATOENCEPHALIC BARRIER |
| US6864232B1 (en) | 1998-12-24 | 2005-03-08 | Sucampo Ag | Agent for treating visual cell function disorder |
| CA2358967A1 (en) | 1999-01-27 | 2000-08-03 | Zielinski Laboratory | Hesperitin pro-forms with enhanced bioavailability |
| BR0010459A (pt) | 1999-03-11 | 2002-02-05 | Fujisawa Pharmaceutical Co | Preparação de lipossoma contendo derivado de ácido pipecólico e preparação sólida |
| JP3750527B2 (ja) | 1999-05-25 | 2006-03-01 | アステラス製薬株式会社 | 類似有機化合物を分離する方法 |
| AUPQ078799A0 (en) | 1999-06-04 | 1999-06-24 | Fujisawa Pharmaceutical Co., Ltd. | New use |
| FI20000004A0 (fi) * | 2000-01-03 | 2000-01-03 | Slk Foundation | Flavonoidilääke... |
| US7084126B1 (en) | 2000-05-01 | 2006-08-01 | Healthpartners Research Foundation | Methods and compositions for enhancing cellular function through protection of tissue components |
| JP2004510694A (ja) * | 2000-05-08 | 2004-04-08 | ヘインズ デイビッド | 免疫抑制性組成物 |
| FR2815033B1 (fr) | 2000-10-06 | 2003-09-05 | Negma Lab | Derives de 7-carboxy-flavones, porcede pour leur preparation et leur application en therapeutique |
| DE10056400A1 (de) | 2000-11-14 | 2002-05-23 | Merck Patent Gmbh | Galenische Formulierung |
| US20040091477A1 (en) | 2001-05-08 | 2004-05-13 | David Haines | Immunosuppresive compositions |
| MXPA04002077A (es) | 2001-09-06 | 2005-02-17 | Synorx Inc | Inhibicion por 3-doxiflavonoides de actividad de t-linfocitos y terapias relacionadas. |
| US20040102386A1 (en) | 2001-09-06 | 2004-05-27 | Thomas Lahey | Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto |
| GB0125532D0 (en) | 2001-10-24 | 2001-12-12 | Burton Michael | Enzyme activity indicators |
| BR0306858A (pt) | 2002-01-10 | 2004-11-03 | Novartis Ag | Sistemas de liberação de drogas para a prevenção e tratamento de doenças vasculares compreendendo rapamicina e derivados da mesma |
| US7169763B2 (en) | 2002-02-22 | 2007-01-30 | Oliver Yoa-Pu Hu | Cytochrome P450 3A inhibitors and enhancers |
| GB2391471B (en) | 2002-08-02 | 2005-05-04 | Satishchandra Punambhai Patel | Pharmaceutical compositions |
| GB2391473B (en) | 2002-08-02 | 2004-07-07 | Satishchandra Punambhai Patel | Pharmaceutical compositions |
| US20060100179A1 (en) | 2002-08-14 | 2006-05-11 | Pero Ronald W | Compositions and methods for use in targeting vascular destruction |
| US20050080021A1 (en) | 2002-08-15 | 2005-04-14 | Joseph Tucker | Nitric oxide donating derivatives of stilbenes, polyphenols and flavonoids for the treatment of cardiovascular disorders |
| US20050080024A1 (en) | 2002-08-15 | 2005-04-14 | Joseph Tucker | Nitric oxide donating derivatives for the treatment of cardiovascular disorders |
| DE10240923A1 (de) | 2002-09-02 | 2004-03-04 | Merck Patent Gmbh | Flavonoid-Derivate zur Ekzem-Behandlung |
| US20040209850A1 (en) | 2003-04-15 | 2004-10-21 | Theraquest Biosciences, Llc | Methods of treating pain and compositions for use therefor |
| WO2004100868A2 (en) | 2003-04-23 | 2004-11-25 | Abbott Laboratories | Method of treating transplant rejection |
| MXPA05013324A (es) | 2003-06-10 | 2006-03-09 | Astellas Pharma Inc | Preparacion de aerosol comprendiendo un anexo que incluye una composicion de aerosol conteniendo compuesto macrolido. |
| JP2007509035A (ja) | 2003-10-10 | 2007-04-12 | レスバーロジックス コーポレイション | Egr−1エンハンサー要素に関連する疾患の処置 |
| DE102004002787A1 (de) | 2004-01-19 | 2005-08-11 | Merck Patent Gmbh | Flavonoid-Komplexe |
| WO2005075449A1 (en) | 2004-02-03 | 2005-08-18 | Yale University | Compounds and methods to increase anti-p-glycoprotein activity of baicalein by alkylation on the a ring |
| CN1297552C (zh) | 2004-03-11 | 2007-01-31 | 南京莱尔生物化工有限公司 | 木犀草素的合成方法 |
| BRPI0513395A (pt) | 2004-07-16 | 2008-05-06 | Novartis Ag | uso de um esteróide para aumentar a permeabilidade cutánea |
| US20060014677A1 (en) | 2004-07-19 | 2006-01-19 | Isotechnika International Inc. | Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds |
| EP1799228B1 (en) | 2004-09-14 | 2010-04-14 | Ajinomoto Omnichem S.A. | Topical compositions containing phosphorylated polyphenols |
| US20060069042A1 (en) | 2004-09-24 | 2006-03-30 | Hu Oliver Y | Cytochrome P450 2C9 inhibitors |
| WO2006045010A2 (en) | 2004-10-20 | 2006-04-27 | Resverlogix Corp. | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases |
| CA2587406A1 (en) | 2004-11-16 | 2006-05-26 | Limerick Neurosciences, Inc. | Methods and compositions for treating pain |
| US20070087977A1 (en) | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
| US8017649B2 (en) | 2005-03-11 | 2011-09-13 | Howard Florey Institute Of Experimental Physiology And Medicine | Flavonoid compounds and uses thereof |
| US20080242599A1 (en) | 2005-05-03 | 2008-10-02 | Majd Zayzafoon | Compositions and Methods for Increasing Osteoblast Cell Differentiation and Bone Generation |
| US8410109B2 (en) | 2005-07-29 | 2013-04-02 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
| US20090182003A1 (en) | 2006-01-13 | 2009-07-16 | President And Fellows Of Harvard College | Methods and Compositions for Treatment Cell Proliferative Disorders |
| US20090098137A1 (en) | 2006-04-05 | 2009-04-16 | Novartis Ag | Combinations of therapeutic agents for treating cancer |
| GB0618168D0 (en) | 2006-09-15 | 2006-10-25 | Babraham Inst | Compounds |
| US20080153819A1 (en) | 2006-12-21 | 2008-06-26 | Bingaman David P | Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor |
| CA2673863A1 (en) * | 2006-12-28 | 2008-07-10 | Limerick Biopharma, Inc. | Methods and compositions for therapeutic treatment |
| WO2009018350A1 (en) | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Pyrone analog compositions and methods |
| US20090082400A1 (en) | 2007-07-31 | 2009-03-26 | Ving Lee | Soluble pyrone analogs methods and compositions |
| JP2011500512A (ja) | 2007-07-31 | 2011-01-06 | リメリック バイオファーマ,インコーポレイティド | リン酸化ピロン類似体および方法 |
| WO2009158007A2 (en) | 2008-06-27 | 2009-12-30 | Limerick Biopharma, Inc. | Methods and compositions for therapeutic treatment |
| WO2009158031A2 (en) | 2008-06-27 | 2009-12-30 | Limerick Biopharma, Inc. | Methods and compositions for therapeutic treatment |
| CN102438614A (zh) | 2008-10-10 | 2012-05-02 | 利默里克生物制药公司 | 用于治疗的吡喃酮类似物 |
| US20100297020A1 (en) | 2008-10-10 | 2010-11-25 | Limerick Biopharma, Inc. | Phosphorylated and phosphonated pyrone analogs for therapeutic treatment |
| EP2424541A2 (en) | 2009-04-27 | 2012-03-07 | Limerick BioPharma, Inc. | Phosphorylated and phosphonated pyrone analogs for therapeutic treatment |
-
2008
- 2008-07-30 JP JP2010520153A patent/JP2011500512A/ja not_active Ceased
- 2008-07-30 CN CN2008801055593A patent/CN101969959A/zh active Pending
- 2008-07-30 GB GB1002044A patent/GB2464645B/en not_active Expired - Fee Related
- 2008-07-30 WO PCT/US2008/071588 patent/WO2009018338A2/en not_active Ceased
- 2008-07-30 CA CA2693338A patent/CA2693338A1/en not_active Abandoned
- 2008-07-30 BR BRPI0814876-7A2A patent/BRPI0814876A2/pt not_active Application Discontinuation
- 2008-07-30 US US12/182,992 patent/US7947733B2/en not_active Expired - Fee Related
- 2008-07-30 MX MX2010001141A patent/MX2010001141A/es not_active Application Discontinuation
- 2008-07-30 AU AU2008282261A patent/AU2008282261A1/en not_active Abandoned
- 2008-07-30 EP EP08782531A patent/EP2182957A4/en not_active Withdrawn
- 2008-07-30 TW TW097128884A patent/TW200924785A/zh unknown
- 2008-07-30 KR KR1020107004292A patent/KR20100051829A/ko not_active Withdrawn
-
2010
- 2010-02-18 US US12/708,040 patent/US20100144612A1/en not_active Abandoned
- 2010-02-25 ZA ZA2010/01390A patent/ZA201001390B/en unknown
- 2010-04-22 US US12/765,580 patent/US20100204089A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7947733B2 (en) | 2011-05-24 |
| AU2008282261A1 (en) | 2009-02-05 |
| EP2182957A4 (en) | 2012-07-18 |
| JP2011500512A (ja) | 2011-01-06 |
| TW200924785A (en) | 2009-06-16 |
| GB201002044D0 (en) | 2010-03-24 |
| WO2009018338A2 (en) | 2009-02-05 |
| ZA201001390B (en) | 2011-05-25 |
| US20100204089A1 (en) | 2010-08-12 |
| WO2009018338A3 (en) | 2010-11-11 |
| US20090069273A1 (en) | 2009-03-12 |
| CN101969959A (zh) | 2011-02-09 |
| GB2464645A (en) | 2010-04-28 |
| CA2693338A1 (en) | 2009-02-05 |
| GB2464645B (en) | 2010-11-24 |
| US20100144612A1 (en) | 2010-06-10 |
| KR20100051829A (ko) | 2010-05-18 |
| EP2182957A2 (en) | 2010-05-12 |
| MX2010001141A (es) | 2010-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0813647A2 (pt) | Piperazinil oxoalquil tetrahidro-beta-carbolinas e análogos relacionados | |
| BRPI0814876A2 (pt) | Análogos de pirona fosforilados e métodos | |
| BRPI0821573A2 (pt) | benzofuropirimidonas | |
| ATE501136T1 (de) | Imidazopyridinone | |
| DE502007001207D1 (de) | Elektrosaugkopf | |
| DK2159224T3 (da) | Bromphenylsubstituerede thiazolyldihydropyrimidiner | |
| ATE514696T1 (de) | Diphenyl-dihydro-imidazopyridinone | |
| DE602008002772D1 (de) | Polyvinylpyrrolidonpulverzusammensetzungen | |
| DE112008003636A5 (de) | Mehrzuggruppierer | |
| DE602008000749D1 (de) | Buschschneider | |
| BRPI0811451A2 (pt) | Exopolissacarídeo | |
| DE602008000923D1 (de) | Einzelwaferätzgerät | |
| BRPI0814519A2 (pt) | Organopolissiloxano | |
| BRPI0815547A2 (pt) | Depsipeptídeos cícliocos | |
| BRPI0812840A2 (pt) | 2-imidazolinas | |
| AT505058A3 (de) | Türschliesssystem | |
| BRPI0812994A2 (pt) | Microbiocidas | |
| DE602008004695D1 (de) | Katalysatorträgerwabe | |
| BRPI0809678A2 (pt) | Métodos | |
| DE602008005589D1 (de) | Rliganden | |
| DE112008001216A5 (de) | Magnetronplasmaanlage | |
| DE502008001694D1 (de) | Mitfahrhubwagen | |
| DE112008003094A5 (de) | Geomatte | |
| DE112008003196A5 (de) | Handpipettiergerät | |
| DE602008000292D1 (de) | Werkzeughaltepositioniervorrichtung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |