BRPI0909936A2 - "composição para o envio transdérmico, em particular envio transdérmico iontoforético, de pelo menos um agente ativo catiônico ou um sal do mesmo" - Google Patents

"composição para o envio transdérmico, em particular envio transdérmico iontoforético, de pelo menos um agente ativo catiônico ou um sal do mesmo"

Info

Publication number
BRPI0909936A2
BRPI0909936A2 BRPI0909936A BRPI0909936A BRPI0909936A2 BR PI0909936 A2 BRPI0909936 A2 BR PI0909936A2 BR PI0909936 A BRPI0909936 A BR PI0909936A BR PI0909936 A BRPI0909936 A BR PI0909936A BR PI0909936 A2 BRPI0909936 A2 BR PI0909936A2
Authority
BR
Brazil
Prior art keywords
transdermal delivery
salt
composition
active agent
cationic active
Prior art date
Application number
BRPI0909936A
Other languages
English (en)
Inventor
Andreas Koch
Christoph Schmitz
Michael Horstmann
Mohammad Sameti
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of BRPI0909936A2 publication Critical patent/BRPI0909936A2/pt
Publication of BRPI0909936B1 publication Critical patent/BRPI0909936B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
BRPI0909936-0A 2008-06-19 2009-06-16 Composição para liberação transdérmica BRPI0909936B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13252708P 2008-06-19 2008-06-19
US61/132,527 2008-06-19
PCT/EP2009/004316 WO2009153019A1 (en) 2008-06-19 2009-06-16 Composition for transdermal delivery of cationic active agents

Publications (2)

Publication Number Publication Date
BRPI0909936A2 true BRPI0909936A2 (pt) 2015-10-20
BRPI0909936B1 BRPI0909936B1 (pt) 2019-07-23

Family

ID=40934213

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909936-0A BRPI0909936B1 (pt) 2008-06-19 2009-06-16 Composição para liberação transdérmica

Country Status (16)

Country Link
US (2) US10881606B2 (pt)
EP (2) EP3308777A1 (pt)
JP (2) JP5620907B2 (pt)
KR (1) KR101656537B1 (pt)
CN (2) CN102046157A (pt)
AU (1) AU2009259601B2 (pt)
BR (1) BRPI0909936B1 (pt)
CA (1) CA2728975C (pt)
ES (1) ES2639576T3 (pt)
IL (1) IL210080A (pt)
MX (1) MX351262B (pt)
NZ (1) NZ590510A (pt)
PL (1) PL2285362T3 (pt)
RU (1) RU2517241C2 (pt)
WO (1) WO2009153019A1 (pt)
ZA (1) ZA201007576B (pt)

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WO2015058080A1 (en) * 2013-10-17 2015-04-23 Causwave Inc. System and method for transdermal dialysis
EP3079668A1 (en) 2013-12-09 2016-10-19 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
WO2017119520A1 (ko) * 2016-01-05 2017-07-13 바이오센서연구소 주식회사 역전기 투석을 이용한 마스크팩 및 그를 포함하는 키트
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
CN111491619B (zh) 2017-12-20 2024-06-07 Lts勒曼治疗系统股份公司 用于离子电渗透皮递送曲坦化合物的耐低温的组合物
BR112020010195A2 (pt) * 2017-12-20 2020-11-03 Lts Lohmann Therapie-Systeme Ag composição frigoestável para distribuição transdermal iontoforética de um composto de triptano
US11766558B2 (en) 2018-07-30 2023-09-26 Compass Health Brands Corp. Biomedical electrode with anti-microbial properties
US12377112B2 (en) 2019-04-17 2025-08-05 Compass Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
IL291839A (en) 2019-10-01 2022-06-01 Empyrean Neuroscience Inc Genetic engineering of fungi to modulate tryptamine expression
CA3156257A1 (en) 2019-10-03 2021-04-08 Starton Therapeutics, Inc. TRANSDERMAL DELIVERY OF DRONABINOL
US12409131B2 (en) 2019-10-03 2025-09-09 Pike Therapeutics Usa, Inc. Transdermal delivery of dronabinol
US12186280B2 (en) 2019-10-11 2025-01-07 Pike Therapeutics Inc. Pharmaceutical composition and method for treating seizure disorders
US12016829B2 (en) 2019-10-11 2024-06-25 Pike Therapeutics Inc. Pharmaceutical composition and method for treating seizure disorders
US12121617B2 (en) 2019-10-14 2024-10-22 Pike Therapeutics Inc. Transdermal delivery of cannabidiol
US12268699B2 (en) 2019-10-14 2025-04-08 Pike Therapeutics Inc. Transdermal delivery of tetrahydrocannabinol
MX2022004258A (es) 2019-10-14 2022-05-26 Pike Therapeutics Inc Entrega transdermica de cannabidiol.
DE102020106115A1 (de) 2020-03-06 2021-09-09 Lts Lohmann Therapie-Systeme Ag Iontophoretische Zusammensetzung zur Verabreichung von S-Ketamin
AU2021254855A1 (en) * 2020-04-16 2022-09-15 Pike Therapeutics, Inc. Transdermal micro-dosing delivery of psychedelics derivatives
JP7766623B2 (ja) 2020-05-19 2025-11-10 サイビン アイアールエル リミテッド 重水素化トリプタミン誘導体および使用方法
US11312684B1 (en) 2021-02-10 2022-04-26 Eleusis Therapeutics Us, Inc. Pharmaceutically acceptable salts of psilocin and uses thereof
US20240124398A1 (en) * 2021-02-10 2024-04-18 Eleusis Therapeutics Us, Inc. Pharmaceutically acceptable salts of psilocin and uses thereof
JP2024514542A (ja) * 2021-03-31 2024-04-02 ライフ チェンジ, エルエルシー 催幻覚剤の治療的投与のための経皮システム、製剤、および方法
US12378194B2 (en) * 2021-05-25 2025-08-05 Atai Therapeutics, Inc. N, n-dimethyltryptamine salts and crystalline salt forms
CN118234491A (zh) * 2021-05-26 2024-06-21 明德赛特制药公司 致幻剂-脂肪酸组合
CN118984868A (zh) 2021-12-31 2024-11-19 恩派瑞安神经科学公司 用于产生精神药物生物碱的遗传修饰的生物体
EP4486448A1 (en) 2022-03-04 2025-01-08 Reset Pharmaceuticals, Inc. Co-crystals or salts comprising psilocin

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Also Published As

Publication number Publication date
JP2011524389A (ja) 2011-09-01
ES2639576T3 (es) 2017-10-27
ZA201007576B (en) 2011-08-31
US20200113819A1 (en) 2020-04-16
JP2015007080A (ja) 2015-01-15
CA2728975A1 (en) 2009-12-23
US10881606B2 (en) 2021-01-05
IL210080A (en) 2016-03-31
IL210080A0 (en) 2011-02-28
WO2009153019A1 (en) 2009-12-23
CA2728975C (en) 2016-06-07
US20110111029A1 (en) 2011-05-12
US10881607B2 (en) 2021-01-05
CN105456181A (zh) 2016-04-06
RU2010150880A (ru) 2012-06-20
BRPI0909936B1 (pt) 2019-07-23
RU2517241C2 (ru) 2014-05-27
MX2010013853A (es) 2011-03-15
EP3308777A1 (en) 2018-04-18
AU2009259601B2 (en) 2014-09-18
JP5620907B2 (ja) 2014-11-05
MX351262B (es) 2017-10-06
KR101656537B1 (ko) 2016-09-09
KR20110028361A (ko) 2011-03-17
NZ590510A (en) 2012-08-31
EP2285362A1 (en) 2011-02-23
AU2009259601A1 (en) 2009-12-23
PL2285362T3 (pl) 2017-12-29
CN102046157A (zh) 2011-05-04
EP2285362B1 (en) 2017-08-09

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
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