BRPI0911170A2 - processo para a preparação de derivados do ácido ciclo-hexanocarboxílico via o correpondente derivado de ciclo-hexanocarboxamida - Google Patents

processo para a preparação de derivados do ácido ciclo-hexanocarboxílico via o correpondente derivado de ciclo-hexanocarboxamida

Info

Publication number
BRPI0911170A2
BRPI0911170A2 BRPI0911170A BRPI0911170A BRPI0911170A2 BR PI0911170 A2 BRPI0911170 A2 BR PI0911170A2 BR PI0911170 A BRPI0911170 A BR PI0911170A BR PI0911170 A BRPI0911170 A BR PI0911170A BR PI0911170 A2 BRPI0911170 A2 BR PI0911170A2
Authority
BR
Brazil
Prior art keywords
acid derivatives
cyclohexanecarboxylic acid
derivatives via
preparing
cyclohexanecarboxamide
Prior art date
Application number
BRPI0911170A
Other languages
English (en)
Inventor
Helmut Stahr
Michael Jansen
Reinhard Reents
Ursula Hoffmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0911170A2 publication Critical patent/BRPI0911170A2/pt
Publication of BRPI0911170B1 publication Critical patent/BRPI0911170B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/30—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/58—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C07C319/06—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols from sulfides, hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0911170-0A 2008-04-04 2009-03-26 Processo para a preparação de derivados do ácido ciclo-hexanocarboxílico via o correpondente derivado de ciclo-hexanocarboxamida BRPI0911170B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP08154077.5 2008-04-04
EP08154077 2008-04-04
EP09151070 2009-01-22
EP09151070.1 2009-01-22
PCT/EP2009/053584 WO2009121789A1 (en) 2008-04-04 2009-03-26 New process for the preparation of cyclohexanecarboxylic acid derivatives via the corresponding cyclohexanecarboxamide derivative

Publications (2)

Publication Number Publication Date
BRPI0911170A2 true BRPI0911170A2 (pt) 2015-10-13
BRPI0911170B1 BRPI0911170B1 (pt) 2018-05-29

Family

ID=40822950

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911170-0A BRPI0911170B1 (pt) 2008-04-04 2009-03-26 Processo para a preparação de derivados do ácido ciclo-hexanocarboxílico via o correpondente derivado de ciclo-hexanocarboxamida

Country Status (12)

Country Link
US (1) US7858823B2 (pt)
EP (1) EP2274264B1 (pt)
JP (1) JP5526120B2 (pt)
KR (1) KR101290935B1 (pt)
CN (1) CN101952236B (pt)
AU (1) AU2009231424B2 (pt)
BR (1) BRPI0911170B1 (pt)
CA (1) CA2717959C (pt)
ES (1) ES2460900T3 (pt)
IL (1) IL207655A (pt)
MX (1) MX2010009876A (pt)
WO (1) WO2009121789A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009231423B2 (en) * 2008-04-04 2014-01-30 F. Hoffmann-La Roche Ag New process for the preparation of cyclohexanecarboxylic acid derivatives
CN101776652B (zh) * 2010-01-11 2012-07-04 湘潭大学 由氮氧化合物生产的亚硝酰硫酸溶液中的亚硝酰硫酸、硫酸与三氧化硫含量的分析方法
EP2651882B1 (en) * 2010-12-16 2018-11-14 F.Hoffmann-La Roche Ag Process for the preparation of aromatic thiol derivatives by hydrogenation of disulfides
US8975438B2 (en) * 2011-07-13 2015-03-10 Hoffmann-La Roche Inc. Process for the preparation of cyclohexanecarboxylic acid derivatives
PT2978859T (pt) 2013-03-27 2018-10-04 Hoffmann La Roche Marcadores genéticos para previsão da capacidade de resposta à terapêutica
RU2703192C2 (ru) 2014-07-30 2019-10-15 Ф. Хоффманн-Ля Рош Аг Генетические маркеры для прогнозирования ответа на терапию поднимающими уровень hdl или имитирующими hdl агентами

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2899458A (en) * 1959-08-11 Process for producing oxy aromatic
US3320305A (en) * 1964-01-28 1967-05-16 Exxon Research Engineering Co Process for converting nitriles
US4129595A (en) * 1978-03-29 1978-12-12 Chevron Research Company Preparation of chloroacetyl chloride
CH641756A5 (fr) * 1978-04-27 1984-03-15 Sanofi Sa Composes derives de l'acide cyclohexylcarboxylique, et medicaments les contenant.
DE3218540A1 (de) * 1982-05-17 1983-11-24 Hoechst Ag, 6230 Frankfurt Spiro-2-aza-alkan-3-carbonitrile, verfahren zu ihrer herstellung und ihre verwendung
JP2894445B2 (ja) * 1997-02-12 1999-05-24 日本たばこ産業株式会社 Cetp活性阻害剤として有効な化合物
IT1292037B1 (it) 1997-05-30 1999-01-25 Bracco Spa Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
JP2000154171A (ja) * 1998-11-18 2000-06-06 Showa Denko Kk シアノ安息香酸化合物の製造法
GB0229803D0 (en) 2002-12-20 2003-01-29 Syngenta Ltd Chemical process
ITMI20031333A1 (it) 2003-06-30 2005-01-01 Erregierre Spa Processo di preparazione di raloxifene cloridrato.
US7435849B2 (en) * 2005-10-31 2008-10-14 Hoffmann-La Roche Inc. Process for the production of acid chlorides
EP1935867A1 (en) * 2006-12-20 2008-06-25 F. Hoffmann-La Roche Ag Process for preparing 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid

Also Published As

Publication number Publication date
JP2011516448A (ja) 2011-05-26
US7858823B2 (en) 2010-12-28
IL207655A (en) 2014-11-30
EP2274264B1 (en) 2014-02-12
AU2009231424B2 (en) 2014-01-30
CA2717959A1 (en) 2009-10-08
JP5526120B2 (ja) 2014-06-18
ES2460900T3 (es) 2014-05-14
BRPI0911170B1 (pt) 2018-05-29
KR101290935B1 (ko) 2013-07-29
KR20100119898A (ko) 2010-11-11
EP2274264A1 (en) 2011-01-19
CN101952236B (zh) 2014-07-02
MX2010009876A (es) 2010-09-28
CA2717959C (en) 2016-03-22
CN101952236A (zh) 2011-01-19
US20090253927A1 (en) 2009-10-08
IL207655A0 (en) 2010-12-30
WO2009121789A1 (en) 2009-10-08
AU2009231424A1 (en) 2009-10-08

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08E Application fees: payment of additional fee required [chapter 8.5 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/03/2009, OBSERVADAS AS CONDICOES LEGAIS.