BRPI0911439A2 - agentes e métodos para recrutamento de célula-tronco pluripotente derivada da medula óssea para a circulação periférica - Google Patents
agentes e métodos para recrutamento de célula-tronco pluripotente derivada da medula óssea para a circulação periféricaInfo
- Publication number
- BRPI0911439A2 BRPI0911439A2 BRPI0911439A BRPI0911439A BRPI0911439A2 BR PI0911439 A2 BRPI0911439 A2 BR PI0911439A2 BR PI0911439 A BRPI0911439 A BR PI0911439A BR PI0911439 A BRPI0911439 A BR PI0911439A BR PI0911439 A2 BRPI0911439 A2 BR PI0911439A2
- Authority
- BR
- Brazil
- Prior art keywords
- recruitment
- agents
- methods
- stem cell
- bone marrow
- Prior art date
Links
- 210000001185 bone marrow Anatomy 0.000 title 1
- 230000003836 peripheral circulation Effects 0.000 title 1
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
- 230000007115 recruitment Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Marine Sciences & Fisheries (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008119348 | 2008-04-30 | ||
| PCT/JP2009/058515 WO2009133939A1 (ja) | 2008-04-30 | 2009-04-30 | 末梢循環への骨髄由来多能性幹細胞動員薬 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0911439A2 true BRPI0911439A2 (pt) | 2016-07-12 |
Family
ID=41255154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0911439A BRPI0911439A2 (pt) | 2008-04-30 | 2009-04-30 | agentes e métodos para recrutamento de célula-tronco pluripotente derivada da medula óssea para a circulação periférica |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8673580B2 (pt) |
| EP (1) | EP2301559A4 (pt) |
| JP (2) | JP5660889B2 (pt) |
| KR (1) | KR101728379B1 (pt) |
| CN (1) | CN102076350A (pt) |
| AU (1) | AU2009240884B8 (pt) |
| BR (1) | BRPI0911439A2 (pt) |
| CA (1) | CA2722852A1 (pt) |
| RU (1) | RU2519714C2 (pt) |
| WO (1) | WO2009133939A1 (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009133943A1 (ja) | 2008-04-30 | 2009-11-05 | 株式会社ジェノミックス | 生体内機能的細胞の高効率採取法 |
| CN102076351A (zh) * | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | 损伤组织的功能性再生促进药物 |
| KR20120135190A (ko) | 2009-10-28 | 2012-12-12 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제 |
| EP3358011B1 (en) * | 2011-04-26 | 2020-03-04 | StemRIM Inc. | Peptide for inducing regeneration of tissue and use thereof |
| US9244074B2 (en) * | 2011-06-07 | 2016-01-26 | University Of Hawaii | Biomarker of asbestos exposure and mesothelioma |
| US9561274B2 (en) | 2011-06-07 | 2017-02-07 | University Of Hawaii | Treatment and prevention of cancer with HMGB1 antagonists |
| CN102899396B (zh) * | 2012-07-25 | 2015-02-18 | 山东省农业科学院奶牛研究中心 | 影响奶牛乳腺炎易感/抗性hmgb3基因的核心启动子及其功能性分子标记与应用 |
| DK2913059T3 (en) | 2012-10-25 | 2018-06-25 | Genomix Co Ltd | Hitherto UNKNOWN PROCEDURE FOR TREATMENT OF SPINE INJURY USING HMGB1 FRAGMENT |
| JP6253589B2 (ja) | 2012-10-25 | 2017-12-27 | 株式会社ジェノミックス | Hmgb1断片を利用した新規心筋梗塞の治療法 |
| JP6941417B2 (ja) * | 2016-02-04 | 2021-09-29 | 雪印メグミルク株式会社 | 軟骨機能改善剤 |
| KR20190015712A (ko) | 2016-05-03 | 2019-02-14 | 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 | 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법 |
| AU2018213671B2 (en) | 2017-01-27 | 2024-06-06 | Osaka University | Therapeutic agent for cardiomyopathy, old myocardial infarction and chronic heart failure |
| MX2019012738A (es) | 2017-04-25 | 2020-02-07 | Shionogi & Co | Peptido para inducir la regeneracion de tejido, y uso del mismo. |
| EP3718561A4 (en) | 2017-12-01 | 2021-07-21 | Stemrim Inc. | Therapy for inflammatory bowel disease |
| AU2018376452A1 (en) | 2017-12-01 | 2020-06-25 | Osaka University | Ectodermal mesenchymal stem cells and method for producing same |
| CN108165521A (zh) * | 2017-12-29 | 2018-06-15 | 广西医科大学第附属医院 | 一种接近cin患者血清hmgb-1含量的体外细胞培养方法 |
| CN108300687A (zh) * | 2017-12-29 | 2018-07-20 | 广西医科大学第附属医院 | 一种基于肾小管上皮细胞培养造影剂损伤模型的方法 |
| US20210024594A1 (en) | 2018-02-08 | 2021-01-28 | StemRIM Inc. | Therapeutic Agent for Psoriasis |
| WO2020071520A1 (ja) | 2018-10-05 | 2020-04-09 | 株式会社ステムリム | 間葉系幹細胞の動員活性を有するペプチド |
| US12304933B2 (en) | 2018-10-05 | 2025-05-20 | StemRIM Inc. | Disease treatment drug based on mesenchymal-stem-cell mobilization |
| JP7555583B2 (ja) * | 2019-01-31 | 2024-09-25 | 国立大学法人大阪大学 | 母児間免疫寛容を誘導する方法 |
| WO2021020509A1 (ja) * | 2019-07-31 | 2021-02-04 | 株式会社ステムリム | 間葉系幹細胞の増殖促進または減少抑制のための組成物 |
| IL296982B2 (en) * | 2020-04-03 | 2026-04-01 | Stemrim Inc | Peptide having mesenchymal stem cell mobilizing activity |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4005A (en) * | 1845-04-22 | Improvement in the manufacture of indurated rubber fabrics | ||
| US5658894A (en) | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
| JP3018313B2 (ja) | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
| US6720340B1 (en) | 1999-07-28 | 2004-04-13 | The Board Of Trustees Of The Leland Stanford Jr. University | Nicotine receptor agonists in stem cell and progenitor cell recruitment |
| EP1114862A3 (de) | 1999-11-17 | 2003-08-06 | Switch Biotech Aktiengesellschaft | Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankungen sowie ihre Verwendung zur Identifizierung von pharmakologisch aktiven Substanzen |
| HK1052372A1 (zh) | 2000-02-24 | 2003-09-11 | Xcyte Therapies, Inc. | 细胞的同步刺激和富集 |
| JP3421741B2 (ja) | 2000-05-18 | 2003-06-30 | 筑波大学長 | 人工骨髄、血球細胞の増殖方法 |
| US20040191246A1 (en) | 2003-02-26 | 2004-09-30 | Connelly Patrick R. | Process for in vivo treatment of specific biological targets in bodily fluid |
| ITMI20010562A1 (it) | 2001-03-16 | 2002-09-16 | Marco E Bianchi | Inibitori o antagonisti della proteina hmg1 per il trattamento di disordini vascolari |
| DE10121254A1 (de) | 2001-04-30 | 2002-11-07 | Switch Biotech Ag | MRP8/MRP14 Heterodimers oder seiner Einzelkomponenten alleine oder in Kombination zur Behandlung und/oder Prävention von Hauterkrankungen, Wunden und/oder Wundheilungsstörungen, die durch eine verringerte Menge an MRP8/MRP14 Heterodimeren gekennzeichnet sind |
| EP1390058A2 (en) | 2001-04-30 | 2004-02-25 | Switch Biotech Aktiengesellschaft | Mrp8/mrp14 heterodimer, or its individual components in combination, for treating and/or preventing skin diseases, wounds and/or wound-healing disturbances |
| BR0209689A (pt) | 2001-05-15 | 2006-02-07 | Long Island Jewish Res Inst | Uso de fragmento de hmg como agente anti-inflamatório |
| US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
| ITMI20011986A1 (it) | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
| KR100704158B1 (ko) | 2001-11-19 | 2007-04-05 | 교와 핫꼬 고교 가부시끼가이샤 | 다분화능 줄기세포를 조직으로부터 말초혈로 동원하는약제 |
| DE60326453D1 (de) | 2002-07-03 | 2009-04-16 | Ct Cardiologico Monzino S P A | Die verwendung von hmgb1 zur behandlung von gewebeverletzungen und/oder zur unterstützung der gewebewiederherstellung |
| GB0226251D0 (en) | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
| EP1579221A2 (de) | 2003-01-03 | 2005-09-28 | Alcedo Biotech GmbH | Verwendungen von hmgb, hmgn, hmga proteinen |
| WO2004084928A1 (en) | 2003-03-28 | 2004-10-07 | UNIVERSITé LAVAL | S100 protein as neutrophil activator for alleviating neutropenia in cancer treatment |
| WO2005025604A2 (en) | 2003-09-10 | 2005-03-24 | The General Hospital Corporation | Use of hmgb and hmgb fragments to decrease specific immune response |
| ITRM20040058A1 (it) | 2004-02-03 | 2004-05-03 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di regolare la proliferazione delle cellule muscolari lisce ed endoteliali. |
| US20090062187A1 (en) | 2004-07-20 | 2009-03-05 | Marco Bianchi | Use of Hmgb1 for Wound Healing |
| MX2007001155A (es) | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| KR100593397B1 (ko) | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
| WO2006047820A1 (en) | 2004-11-01 | 2006-05-11 | Newsouth Innovations Pty Limited | Use of calgranulin a and b in the promotion and inhibition of mineralized tissue formation |
| ITRM20050032A1 (it) | 2005-01-21 | 2006-07-22 | Marco E Bianchi | Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica. |
| WO2006114805A2 (en) * | 2005-04-28 | 2006-11-02 | Fondazione Centro San Raffaele Del Monte Tabor | Use of hmgb2 and hmgb3 proteins for medical applications |
| WO2007015546A1 (ja) | 2005-08-04 | 2007-02-08 | Genomix Co., Ltd | 間葉系幹細胞誘導剤及び組織再生促進剤並びに間葉系幹細胞の調製方法 |
| JP5244785B2 (ja) | 2006-08-11 | 2013-07-24 | 小野薬品工業株式会社 | ストローマ由来因子−1(sdf−1)に対するモノクローナル抗体 |
| CA2636788A1 (en) | 2006-10-30 | 2008-05-08 | Genomix Co., Ltd. | Hmgb protein for use in promoting tissue regeneration |
| WO2009133943A1 (ja) * | 2008-04-30 | 2009-11-05 | 株式会社ジェノミックス | 生体内機能的細胞の高効率採取法 |
| CN102076351A (zh) | 2008-04-30 | 2011-05-25 | 吉诺米克斯股份有限公司 | 损伤组织的功能性再生促进药物 |
| JP5393664B2 (ja) * | 2008-05-30 | 2014-01-22 | Hoya株式会社 | レンズ用鋳型の製造方法 |
-
2009
- 2009-04-30 JP JP2010510168A patent/JP5660889B2/ja active Active
- 2009-04-30 EP EP09738876A patent/EP2301559A4/en not_active Withdrawn
- 2009-04-30 CA CA2722852A patent/CA2722852A1/en not_active Abandoned
- 2009-04-30 CN CN2009801252401A patent/CN102076350A/zh active Pending
- 2009-04-30 RU RU2010148792/15A patent/RU2519714C2/ru not_active IP Right Cessation
- 2009-04-30 WO PCT/JP2009/058515 patent/WO2009133939A1/ja not_active Ceased
- 2009-04-30 US US12/990,047 patent/US8673580B2/en not_active Expired - Fee Related
- 2009-04-30 KR KR1020107026779A patent/KR101728379B1/ko not_active Expired - Fee Related
- 2009-04-30 BR BRPI0911439A patent/BRPI0911439A2/pt not_active IP Right Cessation
- 2009-04-30 AU AU2009240884A patent/AU2009240884B8/en not_active Ceased
-
2014
- 2014-09-17 JP JP2014188899A patent/JP6002727B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009240884A1 (en) | 2009-11-05 |
| US20110091928A1 (en) | 2011-04-21 |
| EP2301559A1 (en) | 2011-03-30 |
| AU2009240884B2 (en) | 2014-02-13 |
| EP2301559A4 (en) | 2012-05-02 |
| JPWO2009133939A1 (ja) | 2011-09-01 |
| US8673580B2 (en) | 2014-03-18 |
| JP2015038094A (ja) | 2015-02-26 |
| AU2009240884A2 (en) | 2011-02-10 |
| JP6002727B2 (ja) | 2016-10-05 |
| KR20110028440A (ko) | 2011-03-18 |
| AU2009240884A8 (en) | 2014-03-06 |
| AU2009240884B8 (en) | 2014-03-06 |
| WO2009133939A1 (ja) | 2009-11-05 |
| RU2010148792A (ru) | 2012-06-10 |
| KR101728379B1 (ko) | 2017-04-19 |
| CN102076350A (zh) | 2011-05-25 |
| RU2519714C2 (ru) | 2014-06-20 |
| CA2722852A1 (en) | 2009-11-05 |
| JP5660889B2 (ja) | 2015-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2512 DE 26-02-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |