BRPI0911571A2 - método para tratar um mamífero, análogo de insulina, ácido nucléico e célula hospedeira - Google Patents

método para tratar um mamífero, análogo de insulina, ácido nucléico e célula hospedeira

Info

Publication number: BRPI0911571A2
Authority: BR; Brazil
Prior art keywords: mammal; treating; nucleic acid; host cell; insulin analog
Prior art date: 2008-04-22

Application number

BRPI0911571A

Other languages

English (en)

Inventor

Whittaker Jonathan

Weiss Michael

Original Assignee

Univ Case Western Reserve

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-04-22

Filing date

2009-04-22

Publication date

2018-04-03

2009-04-22 Application filed by Univ Case Western Reserve filed Critical Univ Case Western Reserve

2018-04-03 Publication of BRPI0911571A2 publication Critical patent/BRPI0911571A2/pt

Links

241000124008 Mammalia Species 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 1
239000004026 insulin derivative Substances 0.000 title 1
150000007523 nucleic acids Chemical class 0.000 title 1
102000039446 nucleic acids Human genes 0.000 title 1
108020004707 nucleic acids Proteins 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Obesity (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

BRPI0911571A 2008-04-22 2009-04-22 método para tratar um mamífero, análogo de insulina, ácido nucléico e célula hospedeira BRPI0911571A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4698508P	2008-04-22	2008-04-22
PCT/US2009/041439 WO2009132129A2 (en)	2008-04-22	2009-04-22	Isoform-specific insulin analogues

Publications (1)

Publication Number	Publication Date
BRPI0911571A2 true BRPI0911571A2 (pt)	2018-04-03

Family

ID=41217411

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0911571A BRPI0911571A2 (pt)	2008-04-22	2009-04-22	método para tratar um mamífero, análogo de insulina, ácido nucléico e célula hospedeira

Country Status (12)

Country	Link
US (1)	US20110195896A1 (pt)
EP (1)	EP2296692A4 (pt)
JP (1)	JP2011521621A (pt)
KR (1)	KR20110021758A (pt)
CN (1)	CN102065885A (pt)
AU (1)	AU2009240636A1 (pt)
BR (1)	BRPI0911571A2 (pt)
CA (1)	CA2722168A1 (pt)
MX (1)	MX2010011329A (pt)
NZ (1)	NZ588857A (pt)
RU (1)	RU2010147076A (pt)
WO (1)	WO2009132129A2 (pt)

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US8399407B2 (en)	2009-09-17	2013-03-19	Case Western Reserve University	Non-standard insulin analogues
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US9707276B2 (en)	2012-12-03	2017-07-18	Merck Sharp & Dohme Corp.	O-glycosylated carboxy terminal portion (CTP) peptide-based insulin and insulin analogues
AU2014232894B2 (en) *	2013-03-15	2018-02-08	Case Western Reserve University	Site 2 insulin analogues
AU2014329567B2 (en)	2013-10-04	2019-07-25	Merck Sharp & Dohme Corp.	Glucose-responsive insulin conjugates
US9988429B2 (en)	2013-10-17	2018-06-05	Zealand Pharma A/S	Glucagon analogues
LT3057984T (lt)	2013-10-17	2018-12-27	Zealand Pharma A/S	Acilinti gliukagono analogai
AU2014345569B2 (en)	2013-11-06	2020-08-13	Zealand Pharma A/S	GIP-GLP-1 dual agonist compounds and methods
KR102310392B1 (ko)	2013-11-06	2021-10-13	질랜드 파마 에이/에스	글루카곤-ｇｌｐ-1-ｇｉｐ 삼원 효능제 화합물
KR102351111B1 (ko)	2014-01-13	2022-01-14	써멀린 다이어비티즈, 엘엘씨	초속효성 인슐린 제형 및 약제학적 전달 시스템
CA2961037A1 (en)	2014-10-06	2016-04-14	Case Western Reserve University	Biphasic single-chain insulin analogues
RU2716985C2 (ru)	2014-10-29	2020-03-17	Зилэнд Фарма А/С	Соединения-агонисты gip и способы
PH12017500935A1 (en)	2014-11-21	2017-11-27	Merck Sharp & Dohme	Insulin receptor partial agonists
JP6989385B2 (ja)	2015-04-16	2022-01-05	ジーランドファーマアクティーゼルスカブ	アシル化グルカゴン類似体
AR105616A1 (es)	2015-05-07	2017-10-25	Lilly Co Eli	Proteínas de fusión
UY36870A (es) *	2015-08-28	2017-03-31	Hanmi Pharm Ind Co Ltd	Análogos de insulina novedosos
EP3344651B1 (en)	2015-09-02	2022-03-02	Merck Sharp & Dohme Corp.	A process for obtaining insulin with correctly formed disulfide bonds
JP6951825B2 (ja)	2015-09-04	2021-10-20	ザスクリプスリサーチインスティテュート	インスリン免疫グロブリン融合タンパク質
EP3393498A4 (en) *	2015-12-23	2019-08-07	Case Western Reserve University	SECULATION OF ULTRASTABILEN INSULIN ANALOGUE WITH POLYMER MELTS
EP3448417B1 (en)	2016-04-26	2025-11-12	Merck Sharp & Dohme LLC	Insulin dimer-incretin conjugates
EP3922260A3 (en)	2016-05-24	2022-06-15	Merck Sharp & Dohme Corp.	Insulin receptor partial agonists and glp-1 analogues
EP3463413A4 (en)	2016-05-25	2020-03-04	Merck Sharp & Dohme Corp.	INSULIN RECEPTOR PART AGONISTS
WO2017210077A1 (en) *	2016-06-02	2017-12-07	Indiana University Research And Technology Corporation	Single chain insulin prodrugs
US20190282710A1 (en)	2016-07-18	2019-09-19	Eth Zurich	B-cell-mimetic cells
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US8399407B2 (en) *	2009-09-17	2013-03-19	Case Western Reserve University	Non-standard insulin analogues
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2009
- 2009-04-22 WO PCT/US2009/041439 patent/WO2009132129A2/en not_active Ceased
- 2009-04-22 JP JP2011506432A patent/JP2011521621A/ja active Pending
- 2009-04-22 CN CN2009801244782A patent/CN102065885A/zh active Pending
- 2009-04-22 MX MX2010011329A patent/MX2010011329A/es not_active Application Discontinuation
- 2009-04-22 US US12/989,399 patent/US20110195896A1/en not_active Abandoned
- 2009-04-22 BR BRPI0911571A patent/BRPI0911571A2/pt not_active IP Right Cessation
- 2009-04-22 AU AU2009240636A patent/AU2009240636A1/en not_active Abandoned
- 2009-04-22 EP EP09734135A patent/EP2296692A4/en not_active Withdrawn
- 2009-04-22 KR KR1020107025017A patent/KR20110021758A/ko not_active Withdrawn
- 2009-04-22 CA CA2722168A patent/CA2722168A1/en not_active Abandoned
- 2009-04-22 RU RU2010147076/10A patent/RU2010147076A/ru not_active Application Discontinuation
- 2009-04-22 NZ NZ588857A patent/NZ588857A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU2009240636A1 (en)	2009-10-29
US20110195896A1 (en)	2011-08-11
KR20110021758A (ko)	2011-03-04
CN102065885A (zh)	2011-05-18
MX2010011329A (es)	2011-03-15
CA2722168A1 (en)	2009-10-29
NZ588857A (en)	2012-07-27
WO2009132129A3 (en)	2010-01-21
EP2296692A2 (en)	2011-03-23
JP2011521621A (ja)	2011-07-28
WO2009132129A2 (en)	2009-10-29
EP2296692A4 (en)	2012-06-06
RU2010147076A (ru)	2012-05-27

Legal Events

Date	Code	Title	Description
2018-04-10	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A, 7A, 8A E 9A ANUIDADES.
2018-07-31	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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