BRPI0911969A2 - quinazolinas substituídas como agente de redução de plaquetas sanguíneas. - Google Patents

quinazolinas substituídas como agente de redução de plaquetas sanguíneas.

Info

Publication number: BRPI0911969A2
Authority: BR; Brazil
Prior art keywords: reducing agent; blood platelet; platelet reducing; substituted quinazolines; quinazolines
Prior art date: 2008-05-16

Application number

BRPI0911969A

Other languages

English (en)

Inventor

Bernard Golding

Kim Hirst

Richard Franklin

Original Assignee

Shire Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-05-16

Filing date

2009-05-13

Publication date

2015-10-13

2009-05-13 Application filed by Shire Llc filed Critical Shire Llc

2015-10-13 Publication of BRPI0911969A2 publication Critical patent/BRPI0911969A2/pt

Links

210000001772 blood platelet Anatomy 0.000 title 1
239000003638 chemical reducing agent Substances 0.000 title 1
150000003246 quinazolines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

BRPI0911969A 2008-05-16 2009-05-13 quinazolinas substituídas como agente de redução de plaquetas sanguíneas. BRPI0911969A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0808950.0A GB0808950D0 (en)	2008-05-16	2008-05-16	Substituted quinazolines
PCT/GB2009/050509 WO2009138789A1 (en)	2008-05-16	2009-05-13	Substituted quinazolines as blood platelet lowering agents

Publications (1)

Publication Number	Publication Date
BRPI0911969A2 true BRPI0911969A2 (pt)	2015-10-13

Family

ID=39596029

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0911969A BRPI0911969A2 (pt)	2008-05-16	2009-05-13	quinazolinas substituídas como agente de redução de plaquetas sanguíneas.

Country Status (10)

Country	Link
US (1)	US20110130405A1 (pt)
EP (1)	EP2297150A1 (pt)
JP (1)	JP2011520859A (pt)
KR (1)	KR20110006726A (pt)
CN (1)	CN102076687A (pt)
AU (1)	AU2009247790A1 (pt)
BR (1)	BRPI0911969A2 (pt)
CA (1)	CA2724213A1 (pt)
GB (1)	GB0808950D0 (pt)
WO (1)	WO2009138789A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7910597B2 (en) *	2006-11-28	2011-03-22	Shire Llc	Substituted quinazolines
US8304420B2 (en) *	2006-11-28	2012-11-06	Shire Llc	Substituted quinazolines for reducing platelet count
PL236023B1 (pl)	2015-04-28	2020-11-30	Politechnika Rzeszowska Im Ignacego Lukasiewicza	Sposób wytwarzania 1-fenylo-2-(2-hydroksyetylo)-6H-imidazo[ 1,5-c]chinazolino-3,5-dionu i 1-fenylo-2-(2-hydroksypropylo)-6H- -imidazo[1,5-c]chinazolino-3,5-dionu
JP2023533016A (ja)	2020-07-11	2023-08-01	ファイザー・インク	抗ウイルス性ヘテロアリールケトン誘導体
US11351149B2 (en)	2020-09-03	2022-06-07	Pfizer Inc.	Nitrile-containing antiviral compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3932407A (en) *	1973-11-19	1976-01-13	Bristol-Myers Company	Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
US3983119A (en) *	1974-11-06	1976-09-28	Bristol-Myers Company	Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
NL7807507A (nl) *	1977-07-25	1979-01-29	Hoffmann La Roche	Tricyclische verbindingen.
JPS5527105A (en) *	1978-08-11	1980-02-27	Dai Ichi Seiyaku Co Ltd	Imidazothienopyrimidinones compound
ZA803535B (en) *	1979-06-20	1981-06-24	Hoffmann La Roche	Novel quinazoline derivatives and pharmaceutical preparations
JPS5677282A (en) *	1979-11-27	1981-06-25	Dai Ichi Seiyaku Co Ltd	3-alkylimidazothienopyrimidin-2-one compound
JPS5785392A (en) *	1980-11-13	1982-05-28	Dai Ichi Seiyaku Co Ltd	2,3-dihydroimidazothienopyrimidine-2-one compound
US4490371A (en) *	1983-02-16	1984-12-25	Syntex (U.S.A.) Inc.	N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides
US4593029A (en) *	1984-02-15	1986-06-03	Syntex (U.S.A.) Inc.	Novel ω-(N-imidazolyl)alkyl ethers of 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
NZ234186A (en) *	1989-07-07	1991-10-25	Janssen Pharmaceutica Nv	Imidazo quinazolin-one derivatives and pharmaceutical compositions
US7700608B2 (en) *	2004-08-04	2010-04-20	Shire Holdings Ag	Quinazoline derivatives and their use in the treatment of thrombocythemia

2008
- 2008-05-16 GB GBGB0808950.0A patent/GB0808950D0/en not_active Ceased
2009
- 2009-05-13 BR BRPI0911969A patent/BRPI0911969A2/pt not_active IP Right Cessation
- 2009-05-13 AU AU2009247790A patent/AU2009247790A1/en not_active Abandoned
- 2009-05-13 US US12/992,997 patent/US20110130405A1/en not_active Abandoned
- 2009-05-13 CN CN2009801248891A patent/CN102076687A/zh active Pending
- 2009-05-13 KR KR1020107027831A patent/KR20110006726A/ko not_active Withdrawn
- 2009-05-13 EP EP09746106A patent/EP2297150A1/en not_active Withdrawn
- 2009-05-13 JP JP2011509013A patent/JP2011520859A/ja active Pending
- 2009-05-13 CA CA2724213A patent/CA2724213A1/en not_active Abandoned
- 2009-05-13 WO PCT/GB2009/050509 patent/WO2009138789A1/en not_active Ceased

Also Published As

Publication number	Publication date
JP2011520859A (ja)	2011-07-21
EP2297150A1 (en)	2011-03-23
GB0808950D0 (en)	2008-06-25
WO2009138789A1 (en)	2009-11-19
CN102076687A (zh)	2011-05-25
US20110130405A1 (en)	2011-06-02
KR20110006726A (ko)	2011-01-20
AU2009247790A1 (en)	2009-11-19
CA2724213A1 (en)	2009-11-19

Legal Events

Date	Code	Title	Description
2015-12-08	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 6A ANUIDADE.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
EP2351595A4 (en)	2012-04-18	Medical connection
BRPI0923823A2 (pt)	2015-07-14	Agente de colaboração.
BRPI0919295A2 (pt)	2015-12-15	1h-benzimidazol-5-carboxamidas como agentes anti-inflamatórios.
PL2452709T3 (pl)	2022-04-04	Kaniula
EP2327448A4 (en)	2012-05-30	defibrillation catheter
EP2296593A4 (en)	2015-01-14	MEDICAL HEAD COVER
PT3476367T (pt)	2020-03-04	Válvula cardíaca transcateter de baixo perfil
EP3858416C0 (en)	2023-11-01	Catheter system
BR112012028519A2 (pt)	2016-07-19	compostos de 2,5,6,7-tetrahidro-[1,4]oxazepin-3-ilamina ou 2,3,6,7-tetrahidro-[1,4]oxazepin-5-ilamina
EP2138200A4 (en)	2011-10-05	SUCTION CATHETER OF A THROMBUS
BRPI1011965A2 (pt)	2016-04-26	estrutura de entressola.
BRPI0920392A2 (pt)	2016-03-22	reservatório de sangue
BRPI0918430A2 (pt)	2015-11-24	4-fenil-1h-pirazóis inseticidas.
BRPI0910615A2 (pt)	2018-04-24	tampão de árvore interno de perfil baixo
EP2213325A4 (en)	2011-02-09	CATHETER
BRPI1008899A2 (pt)	2018-03-13	derivados 3,3´-espiroindolinona como agentes anticâncer
BR112012005247A2 (pt)	2019-09-24	agente antifitoviral
BRPI1012155A2 (pt)	2016-04-05	cateter de segurança.
ATE536905T1 (de)	2011-12-15	Dilatationskatheter
ATE527260T1 (de)	2011-10-15	(dihydro)pyrroloä2,1-aüisoquinoline
EP2216067A4 (en)	2011-11-09	CATHETER
BRPI0911969A2 (pt)	2015-10-13	quinazolinas substituídas como agente de redução de plaquetas sanguíneas.
BRPI0918062A2 (pt)	2015-08-11	Tienilaminopirimidinas como fungicidas
BRPI0923835A2 (pt)	2015-07-21	Agente de formação de espuma
IT1392420B1 (it)	2012-03-02	Lavastoviglie.