BRPI0912865A2 - formação de imagens aprimoradas de células raras enriquecidas de modo imunomagnéticos - Google Patents

formação de imagens aprimoradas de células raras enriquecidas de modo imunomagnéticos

Info

Publication number
BRPI0912865A2
BRPI0912865A2 BRPI0912865A BRPI0912865A BRPI0912865A2 BR PI0912865 A2 BRPI0912865 A2 BR PI0912865A2 BR PI0912865 A BRPI0912865 A BR PI0912865A BR PI0912865 A BRPI0912865 A BR PI0912865A BR PI0912865 A2 BRPI0912865 A2 BR PI0912865A2
Authority
BR
Brazil
Prior art keywords
immunomagnetic
rare cells
enhanced imaging
enriched rare
enriched
Prior art date
Application number
BRPI0912865A
Other languages
English (en)
Inventor
Arjan Tibbe
Frederick Schireuder
Jan Greve
Leon W M M Tertappen
Tycho M Scholtens
Original Assignee
Veridex Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Veridex Llc filed Critical Veridex Llc
Publication of BRPI0912865A2 publication Critical patent/BRPI0912865A2/pt
Publication of BRPI0912865B1 publication Critical patent/BRPI0912865B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/025—High gradient magnetic separators
    • B03C1/031—Component parts; Auxiliary operations
    • B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00—Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02—Details not specific for a particular testing method
    • G01N2203/06—Indicating or recording means; Sensing means
    • G01N2203/0641—Indicating or recording means; Sensing means using optical, X-ray, ultraviolet, infrared or similar detectors
    • G01N2203/0647—Image analysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
BRPI0912865-4A 2008-05-19 2009-05-19 Método para analisar oticamente células raras suspensas em um meio fluido. BRPI0912865B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5421908P 2008-05-19 2008-05-19
US61/054,219 2008-05-19
PCT/US2009/044510 WO2009143149A2 (en) 2008-05-19 2009-05-19 Improved imaging of immunomagnetically enriched rare cells

Publications (2)

Publication Number Publication Date
BRPI0912865A2 true BRPI0912865A2 (pt) 2015-10-06
BRPI0912865B1 BRPI0912865B1 (pt) 2019-06-04

Family

ID=41316540

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0912865-4A BRPI0912865B1 (pt) 2008-05-19 2009-05-19 Método para analisar oticamente células raras suspensas em um meio fluido.

Country Status (12)

Country Link
US (1) US8569077B2 (pt)
EP (1) EP2288919B1 (pt)
JP (1) JP5701749B2 (pt)
KR (1) KR20110013485A (pt)
CN (1) CN102036753B (pt)
BR (1) BRPI0912865B1 (pt)
CA (1) CA2724978C (pt)
ES (1) ES2618078T3 (pt)
HU (1) HUE031851T2 (pt)
IL (1) IL209080A0 (pt)
MX (1) MX2010012565A (pt)
WO (1) WO2009143149A2 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8569077B2 (en) 2008-05-19 2013-10-29 Veridex, Llc Imaging of immunomagnetically enriched rare cells
US8710836B2 (en) 2008-12-10 2014-04-29 Nanomr, Inc. NMR, instrumentation, and flow meter/controller continuously detecting MR signals, from continuously flowing sample material
US8841104B2 (en) 2010-04-21 2014-09-23 Nanomr, Inc. Methods for isolating a target analyte from a heterogeneous sample
US9428547B2 (en) 2010-04-21 2016-08-30 Dna Electronics, Inc. Compositions for isolating a target analyte from a heterogeneous sample
US9476812B2 (en) 2010-04-21 2016-10-25 Dna Electronics, Inc. Methods for isolating a target analyte from a heterogeneous sample
US20110262989A1 (en) 2010-04-21 2011-10-27 Nanomr, Inc. Isolating a target analyte from a body fluid
CN106929401B (zh) * 2011-05-05 2020-06-09 安派科生物医学科技有限公司 肿瘤细胞检测仪
CN102527353A (zh) * 2011-12-21 2012-07-04 深圳市老年医学研究所 一种用于富集循环肿瘤细胞的纳米磁性免疫微球制备
US9995742B2 (en) 2012-12-19 2018-06-12 Dnae Group Holdings Limited Sample entry
US10000557B2 (en) 2012-12-19 2018-06-19 Dnae Group Holdings Limited Methods for raising antibodies
US9434940B2 (en) 2012-12-19 2016-09-06 Dna Electronics, Inc. Methods for universal target capture
US9599610B2 (en) 2012-12-19 2017-03-21 Dnae Group Holdings Limited Target capture system
US9804069B2 (en) 2012-12-19 2017-10-31 Dnae Group Holdings Limited Methods for degrading nucleic acid
US9551704B2 (en) 2012-12-19 2017-01-24 Dna Electronics, Inc. Target detection
US20140242603A1 (en) * 2013-02-26 2014-08-28 Glenn Yaguang Deng Methods and apparatus for target cell magnetic enrichment, isolation and biological analysis
WO2014142559A1 (ko) * 2013-03-13 2014-09-18 고려대학교 산학협력단 혈중 희소 세포의 검출 및 계수 장치와 방법
KR101568573B1 (ko) * 2013-03-13 2015-11-20 고려대학교 산학협력단 혈중 희소 세포의 검출 및 계수 장치와 방법
HRP20201907T1 (hr) 2013-03-15 2021-01-22 Menarini Silicon Biosystems S.P.A. Obogaćivanje cirkulirajućih stanica tumora osiromašenjem bijelih krvnih zrnaca
CN103940997B (zh) * 2014-03-21 2017-01-04 上海柏慧康生物科技有限公司 一种乳腺癌循环肿瘤细胞检测系统及试剂盒
JP6713730B2 (ja) 2015-05-20 2020-06-24 シスメックス株式会社 細胞検出装置および細胞検出方法
CN105891511A (zh) * 2016-05-04 2016-08-24 中山大学附属第医院 用于循环肿瘤细胞和中性粒细胞鉴定的探针及试剂盒

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02118451A (ja) 1988-10-28 1990-05-02 Nippon Telegr & Teleph Corp <Ntt> 細胞性検体スクリーニング方法
US7666308B2 (en) 1996-06-07 2010-02-23 Veridex, Llc. Magnetic separation apparatus and methods
AU3374597A (en) 1996-06-07 1998-01-05 Immunivest Corporation Magnetic separation employing external and internal gradients
US6136182A (en) * 1996-06-07 2000-10-24 Immunivest Corporation Magnetic devices and sample chambers for examination and manipulation of cells
US6790366B2 (en) 1996-06-07 2004-09-14 Immunivest Corporation Magnetic separation apparatus and methods
US6890426B2 (en) 1996-06-07 2005-05-10 Immunivest Corporation Magnetic separation apparatus and methods
AU1747500A (en) * 1998-11-30 2000-06-19 Immunivest Corporation Magnetic separation apparatus and methods
US6249341B1 (en) * 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
DE10301300B4 (de) * 2003-01-15 2009-07-16 Curacyte Chemistry Gmbh Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein
US7282180B2 (en) * 2003-07-02 2007-10-16 Immunivest Corporation Devices and methods to image objects
CA2535301A1 (en) 2003-08-11 2005-03-24 Immunivest Corporation Devices and methods to image objects by time delay integration
CN2695951Y (zh) * 2004-04-27 2005-04-27 任峰 旋转式全自动自清洗血流变检测仪
JP2009537021A (ja) * 2006-05-12 2009-10-22 ベリデックス・リミテッド・ライアビリティ・カンパニー 蛍光顕微鏡法におけるレーザー照射システム
US8569077B2 (en) 2008-05-19 2013-10-29 Veridex, Llc Imaging of immunomagnetically enriched rare cells

Also Published As

Publication number Publication date
JP5701749B2 (ja) 2015-04-15
EP2288919A4 (en) 2011-11-23
US20090286264A1 (en) 2009-11-19
IL209080A0 (en) 2011-01-31
CN102036753A (zh) 2011-04-27
BRPI0912865B1 (pt) 2019-06-04
ES2618078T3 (es) 2017-06-20
WO2009143149A3 (en) 2010-01-14
US8569077B2 (en) 2013-10-29
CA2724978A1 (en) 2009-11-26
CN102036753B (zh) 2016-01-20
HUE031851T2 (en) 2017-08-28
EP2288919B1 (en) 2016-12-21
KR20110013485A (ko) 2011-02-09
MX2010012565A (es) 2010-12-06
CA2724978C (en) 2018-01-23
EP2288919A2 (en) 2011-03-02
JP2011521262A (ja) 2011-07-21
WO2009143149A2 (en) 2009-11-26

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 04/06/2019, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 12A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2622 DE 06-04-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.