BRPI0912927A2 - "método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo" - Google Patents
"método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo"Info
- Publication number
- BRPI0912927A2 BRPI0912927A2 BRPI0912927-8A BRPI0912927A BRPI0912927A2 BR PI0912927 A2 BRPI0912927 A2 BR PI0912927A2 BR PI0912927 A BRPI0912927 A BR PI0912927A BR PI0912927 A2 BRPI0912927 A2 BR PI0912927A2
- Authority
- BR
- Brazil
- Prior art keywords
- individual
- independent tumor
- vegf
- treating
- detecting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
"método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo" são fornecidos métodos para identificar ou diagnosticar tumor independente de vegfs e métodos para tratar tumor independente de vegfs.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9316108P | 2008-08-29 | 2008-08-29 | |
| US61/093,161 | 2008-08-29 | ||
| PCT/US2009/055434 WO2010025414A2 (en) | 2008-08-29 | 2009-08-28 | Diagnostics and treatments for vegf-independent tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0912927A2 true BRPI0912927A2 (pt) | 2019-10-01 |
Family
ID=41571323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0912927-8A BRPI0912927A2 (pt) | 2008-08-29 | 2009-08-28 | "método de detectar um tumor independente de vegf em um indivíduo e método de tratar um tumor independente de vegf em um indivíduo" |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100055099A1 (pt) |
| EP (1) | EP2321433A2 (pt) |
| JP (1) | JP2012501188A (pt) |
| KR (1) | KR20110068987A (pt) |
| CN (1) | CN102137939A (pt) |
| AR (1) | AR073231A1 (pt) |
| AU (1) | AU2009285540A1 (pt) |
| BR (1) | BRPI0912927A2 (pt) |
| CA (1) | CA2734172A1 (pt) |
| IL (1) | IL211088A0 (pt) |
| MX (1) | MX2011002082A (pt) |
| TW (1) | TW201012935A (pt) |
| WO (1) | WO2010025414A2 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2601892C2 (ru) * | 2008-03-06 | 2016-11-10 | Дженентек, Инк. | Комбинированная терапия антагонистами с-мет и egfr |
| ES2363358B1 (es) | 2009-04-03 | 2012-06-21 | FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al | Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable. |
| JP5963005B2 (ja) * | 2010-07-19 | 2016-08-03 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 膵臓癌の治療のためのベバシズマブ組合せ療法のための血漿バイオマーカー |
| EP2704745B1 (en) | 2011-05-05 | 2016-12-14 | Duke University | Methods of developing a prognosis for pancreatic cancer and predicting responsiveness to cancer therapeutics |
| CN103323601B (zh) * | 2012-03-22 | 2016-04-20 | 北京蛋白质组研究中心 | S100a9蛋白检测物在制备筛查肝细胞癌试剂盒中的应用 |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| CN103499694A (zh) * | 2013-10-14 | 2014-01-08 | 中南大学 | 检测结直肠癌及其恶性程度的免疫组化试剂盒 |
| EP3122900A1 (en) | 2014-03-24 | 2017-02-01 | F. Hoffmann-La Roche AG | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression |
| US9968688B2 (en) * | 2014-11-12 | 2018-05-15 | Verily Life Sciences Llc | Shielded targeting agents, methods, and in vivo diagnostic system |
| CN107106688A (zh) * | 2014-11-14 | 2017-08-29 | 豪夫迈·罗氏有限公司 | 预测对vegf拮抗剂的响应 |
| US10037603B2 (en) * | 2015-05-04 | 2018-07-31 | Siemens Healthcare Gmbh | Method and system for whole body bone removal and vascular visualization in medical image data |
| US11499973B2 (en) | 2016-05-17 | 2022-11-15 | Duke University | Methods of predicting responsiveness of a cancer to a VEGF targeting agent and methods of prognosing and treating cancer |
| JP6886854B2 (ja) * | 2017-04-13 | 2021-06-16 | シスメックス株式会社 | 被検物質の情報取得方法 |
| CN107807241A (zh) * | 2017-11-03 | 2018-03-16 | 太原瑞盛生物科技有限公司 | 一种血管内表皮生长因子受体1的磁微粒化学发光检测试剂盒及制备方法 |
| EP3818544B1 (en) * | 2018-07-05 | 2025-05-28 | Boston Scientific Scimed, Inc. | Devices, systems, and methods for determining inflammation and/or fibrosis |
| US12203927B2 (en) | 2019-09-06 | 2025-01-21 | Ut-Battelle, Llc | Methods for immunoregulation by modulating plasminogen-apple-nematode (PAN) domain-containing proteins |
| US20230151434A1 (en) * | 2020-04-07 | 2023-05-18 | The Wistar Institute Of Anatomy And Biology | Reawakening of dormant tumor cells by modified lipids derived from stress activated neutrophils |
| CN111583992B (zh) * | 2020-05-11 | 2023-08-29 | 广州金域医学检验中心有限公司 | Rna水平融合基因突变导致肿瘤的负荷分析系统和方法 |
| CN114958758B (zh) * | 2021-02-18 | 2024-04-23 | 南京启真基因工程有限公司 | 一种乳腺癌模型猪的构建方法及应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030206899A1 (en) * | 1991-03-29 | 2003-11-06 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US6582959B2 (en) * | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| WO1994004679A1 (en) * | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US5686292A (en) * | 1995-06-02 | 1997-11-11 | Genentech, Inc. | Hepatocyte growth factor receptor antagonist antibodies and uses thereof |
| US5880141A (en) * | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
| US20020032315A1 (en) * | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| JP3957765B2 (ja) * | 1997-04-07 | 2007-08-15 | ジェネンテク・インコーポレイテッド | 抗vegf抗体 |
| US6297238B1 (en) * | 1999-04-06 | 2001-10-02 | Basf Aktiengesellschaft | Therapeutic agents |
| US6703020B1 (en) * | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| DE60042021D1 (de) * | 1999-07-29 | 2009-05-28 | Gilead Sciences Inc | Nukleinsäureliganden für den hepatozytischen wachstumsfaktor/dispersionsfaktor (hgf/sf) und seines c-met rezeptors |
| NZ536196A (en) * | 2000-06-23 | 2006-12-22 | Schering Ag | Combinations and compositions which interfere with VEGF/VEGF and angiopoietin/Tie receptor function and their use (II) |
| AU2002303892A1 (en) * | 2001-05-30 | 2002-12-09 | Jingrong Cui | 5-aralkylsulfonyl-3- (pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors |
| EP2258366B1 (en) * | 2001-06-22 | 2013-04-03 | Kirin Pharma Kabushiki Kaisha | Quinoline derivatives capable of inhibiting autophosphorylation of hepatocyte growth factor receptors, and pharmaceutical composition comprising the same |
| EP1463507A1 (en) * | 2001-12-19 | 2004-10-06 | SmithKline Beecham Corporation | Thienopyrimidine compounds as protein tyrosine kinase inhibitors |
| US6790852B2 (en) * | 2002-04-18 | 2004-09-14 | Hoffmann-La Roche Inc. | 2-(2,6-dichlorophenyl)-diarylimidazoles |
| AU2003272740A1 (en) * | 2002-10-01 | 2004-04-23 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 4,6-diaminosubstituted-2-[oxy or aminoxy]-[1,3,5]triazines as protein tyrosine kinase inhibitors |
| CA2517256C (en) * | 2003-02-26 | 2013-04-30 | Sugen, Inc. | Aminoheteroaryl compounds as protein kinase inhibitors |
| WO2004092154A1 (en) * | 2003-04-03 | 2004-10-28 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
| MXPA05012723A (es) * | 2003-05-30 | 2006-02-08 | Genentech Inc | Tratamiento con anticuerpos anti-vgf. |
| EP1644362A2 (en) * | 2003-07-02 | 2006-04-12 | Sugen, Inc. | Indolinone hydrazides as c-met inhibitors |
| US7122548B2 (en) * | 2003-07-02 | 2006-10-17 | Sugen, Inc. | Triazolotriazine compounds and uses thereof |
| US7758859B2 (en) * | 2003-08-01 | 2010-07-20 | Genentech, Inc. | Anti-VEGF antibodies |
| US20050106667A1 (en) * | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| CA2536470A1 (en) * | 2003-08-15 | 2005-02-24 | Vertex Pharmaceuticals Incorporated | Pyrrole compositions useful as inhibitors of c-met |
| AU2004284420A1 (en) * | 2003-09-24 | 2005-05-06 | Vertex Pharmaceuticals Incorporated | 4-azole substituted imidazole compositions useful as inhibitors or c-Met receptor tyrosine kinase |
| WO2005073224A2 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc | Quinoline quinazoline pyridine and pyrimidine counds and their use in the treatment of inflammation angiogenesis and cancer |
| EP1751136B1 (en) * | 2004-05-07 | 2014-07-02 | Amgen Inc. | Nitrogenated heterocyclic derivatives as protein kinase modulators and use for the treatment of angiogenesis and cancer |
| US20060009360A1 (en) * | 2004-06-25 | 2006-01-12 | Robert Pifer | New adjuvant composition |
| BRPI0709425A2 (pt) * | 2006-03-29 | 2011-07-12 | Genentech, Inc. | uso de um antagonista do vegf e método in vitro para diagnosticar um tumor resistente |
-
2009
- 2009-08-28 AR ARP090103324A patent/AR073231A1/es unknown
- 2009-08-28 AU AU2009285540A patent/AU2009285540A1/en not_active Abandoned
- 2009-08-28 TW TW098129171A patent/TW201012935A/zh unknown
- 2009-08-28 KR KR1020117004581A patent/KR20110068987A/ko not_active Withdrawn
- 2009-08-28 EP EP09792080A patent/EP2321433A2/en not_active Withdrawn
- 2009-08-28 JP JP2011525256A patent/JP2012501188A/ja active Pending
- 2009-08-28 CA CA2734172A patent/CA2734172A1/en not_active Abandoned
- 2009-08-28 BR BRPI0912927-8A patent/BRPI0912927A2/pt not_active Application Discontinuation
- 2009-08-28 MX MX2011002082A patent/MX2011002082A/es not_active Application Discontinuation
- 2009-08-28 CN CN2009801338987A patent/CN102137939A/zh active Pending
- 2009-08-28 US US12/550,246 patent/US20100055099A1/en not_active Abandoned
- 2009-08-28 WO PCT/US2009/055434 patent/WO2010025414A2/en not_active Ceased
-
2011
- 2011-02-06 IL IL211088A patent/IL211088A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010025414A2 (en) | 2010-03-04 |
| CN102137939A (zh) | 2011-07-27 |
| EP2321433A2 (en) | 2011-05-18 |
| KR20110068987A (ko) | 2011-06-22 |
| CA2734172A1 (en) | 2010-03-04 |
| MX2011002082A (es) | 2011-06-20 |
| IL211088A0 (en) | 2011-04-28 |
| US20100055099A1 (en) | 2010-03-04 |
| AR073231A1 (es) | 2010-10-20 |
| WO2010025414A3 (en) | 2010-05-14 |
| AU2009285540A1 (en) | 2010-03-04 |
| TW201012935A (en) | 2010-04-01 |
| JP2012501188A (ja) | 2012-01-19 |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] |