BRPI0913197A2 - tieno pirimidinonas substituídas por hidróxi como antagonistas de receptor-1 de hormônio de concentração de melanina - Google Patents

tieno pirimidinonas substituídas por hidróxi como antagonistas de receptor-1 de hormônio de concentração de melanina

Info

Publication number
BRPI0913197A2
BRPI0913197A2 BRPI0913197A BRPI0913197A BRPI0913197A2 BR PI0913197 A2 BRPI0913197 A2 BR PI0913197A2 BR PI0913197 A BRPI0913197 A BR PI0913197A BR PI0913197 A BRPI0913197 A BR PI0913197A BR PI0913197 A2 BRPI0913197 A2 BR PI0913197A2
Authority
BR
Brazil
Prior art keywords
thiene
antagonists
hormone receptor
hydroxy substituted
melanin concentration
Prior art date
Application number
BRPI0913197A
Other languages
English (en)
Inventor
Animesh Goswami
Jeffrey A Robl
Pratik Devasthale
Ramesh N Patel
Saleem Ahmad
William N Washburn
Zhiwei Guo
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BRPI0913197A2 publication Critical patent/BRPI0913197A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BRPI0913197A 2008-05-29 2009-05-28 tieno pirimidinonas substituídas por hidróxi como antagonistas de receptor-1 de hormônio de concentração de melanina BRPI0913197A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5694908P 2008-05-29 2008-05-29
PCT/US2009/045452 WO2009146365A1 (en) 2008-05-29 2009-05-28 Hydroxy substituted thieno pyrimidinones as melanin concentrating hormone receptor-1 antagonists

Publications (1)

Publication Number Publication Date
BRPI0913197A2 true BRPI0913197A2 (pt) 2016-01-12

Family

ID=41017166

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0913197A BRPI0913197A2 (pt) 2008-05-29 2009-05-28 tieno pirimidinonas substituídas por hidróxi como antagonistas de receptor-1 de hormônio de concentração de melanina

Country Status (17)

Country Link
US (1) US7989433B2 (pt)
EP (1) EP2310394A1 (pt)
JP (1) JP2011521962A (pt)
KR (1) KR20110021988A (pt)
CN (1) CN102099360A (pt)
AR (1) AR075260A1 (pt)
AU (1) AU2009251331A1 (pt)
BR (1) BRPI0913197A2 (pt)
CA (1) CA2726264A1 (pt)
CO (1) CO6280492A2 (pt)
EA (1) EA201001882A1 (pt)
IL (1) IL209354A0 (pt)
MX (1) MX2010012803A (pt)
PE (1) PE20091928A1 (pt)
TW (1) TW201000487A (pt)
WO (1) WO2009146365A1 (pt)
ZA (1) ZA201008451B (pt)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
US7851622B2 (en) * 2007-04-25 2010-12-14 Bristol-Myers Squibb Company Non-basic melanin concentrating hormone receptor-1 antagonists
SG183304A1 (en) 2010-02-17 2012-09-27 Takeda Pharmaceutical Heterocyclic compound
CN103957998B (zh) 2011-12-06 2018-06-12 荷兰联合利华有限公司 皮肤抗老化组合物
IL225900A0 (en) * 2013-04-22 2014-03-31 Perrigo Api Ltd A process for the preparation of nicotine that includes the enzymatic reduction of 4-(methylamino)-1-(3-pyridinyl)-1-butanone
EP2921856B1 (en) * 2014-03-18 2016-09-14 Serum Institute Of India Private Limited A quantitative assay for 4-pyrrolidinopyridine (4-ppy) in polysaccharide-protein conjugate vaccines
US20170290333A1 (en) 2014-12-30 2017-10-12 Dow Agrosciences Llc Picolinamide compounds with fungicidal activity
AU2015374459A1 (en) * 2014-12-30 2017-06-29 Dow Agrosciences Llc Picolinamide compounds with fungicidal activity
EP4076527A4 (en) * 2020-01-10 2024-05-15 Consynance Therapeutics, Inc. Therapeutic combinations of drugs and methods of using them
HUP2200222A1 (hu) 2022-06-17 2023-12-28 Richter Gedeon Nyrt MCHR1 antagonisták a Prader-Willi szindróma kezelésére

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Also Published As

Publication number Publication date
JP2011521962A (ja) 2011-07-28
EP2310394A1 (en) 2011-04-20
CA2726264A1 (en) 2009-12-03
US7989433B2 (en) 2011-08-02
AR075260A1 (es) 2011-03-23
EA201001882A1 (ru) 2011-06-30
CO6280492A2 (es) 2011-05-20
IL209354A0 (en) 2011-01-31
TW201000487A (en) 2010-01-01
AU2009251331A1 (en) 2009-12-03
KR20110021988A (ko) 2011-03-04
PE20091928A1 (es) 2009-12-31
ZA201008451B (en) 2012-04-25
US20090298794A1 (en) 2009-12-03
CN102099360A (zh) 2011-06-15
WO2009146365A1 (en) 2009-12-03
MX2010012803A (es) 2010-12-07

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