BRPI0817245A2 - Derivados e quinolina como antagonistas receptores de 5ht5a - Google Patents
Derivados e quinolina como antagonistas receptores de 5ht5aInfo
- Publication number
- BRPI0817245A2 BRPI0817245A2 BRPI0817245-5A BRPI0817245A BRPI0817245A2 BR PI0817245 A2 BRPI0817245 A2 BR PI0817245A2 BR PI0817245 A BRPI0817245 A BR PI0817245A BR PI0817245 A2 BRPI0817245 A2 BR PI0817245A2
- Authority
- BR
- Brazil
- Prior art keywords
- quinoline
- derivatives
- receptor antagonists
- 5ht5a
- 5ht5a receptor
- Prior art date
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 2
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 108010006590 serotonin 5 receptor Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/0047—Detergents in the form of bars or tablets
- C11D17/0065—Solid detergents containing builders
- C11D17/0073—Tablets
- C11D17/0086—Laundry tablets
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/001—Softening compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/50—Perfumes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/50—Perfumes
- C11D3/502—Protected perfumes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D2111/00—Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
- C11D2111/10—Objects to be cleaned
- C11D2111/12—Soft surfaces, e.g. textile
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Detergent Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07117420 | 2007-09-27 | ||
| PCT/EP2008/062416 WO2009040290A1 (en) | 2007-09-27 | 2008-09-18 | Quinoline derivatives as 5ht5a receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0817245A2 true BRPI0817245A2 (pt) | 2015-06-16 |
Family
ID=40336429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0817245-5A BRPI0817245A2 (pt) | 2007-09-27 | 2008-09-18 | Derivados e quinolina como antagonistas receptores de 5ht5a |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20090088451A1 (pt) |
| EP (1) | EP2195296A1 (pt) |
| JP (1) | JP2010540483A (pt) |
| KR (1) | KR101192952B1 (pt) |
| CN (1) | CN101808999B (pt) |
| AR (1) | AR068547A1 (pt) |
| AU (1) | AU2008303602A1 (pt) |
| BR (1) | BRPI0817245A2 (pt) |
| CA (1) | CA2699697A1 (pt) |
| CL (1) | CL2008002864A1 (pt) |
| MX (1) | MX2010003001A (pt) |
| PE (1) | PE20091204A1 (pt) |
| TW (1) | TW200922580A (pt) |
| WO (1) | WO2009040290A1 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009109477A1 (en) * | 2008-03-05 | 2009-09-11 | F. Hoffmann-La Roche Ag | 2-aminoquinolines |
| MX2010008239A (es) * | 2008-03-07 | 2010-08-18 | Hoffmann La Roche | 2-aminoquinolinas. |
| JP2011513452A (ja) * | 2008-03-12 | 2011-04-28 | エフ．ホフマン−ラ ロシュ アーゲー | ５−ｈｔ５ａ受容体アンタゴニストとしての２−アミノキノリン |
| TW201116281A (en) | 2009-08-06 | 2011-05-16 | Astellas Pharma Inc | N atom containing ring acylguanidine derivatives |
| CA2786245A1 (en) | 2010-01-29 | 2011-08-04 | Boehringer Ingelheim International Gmbh | Substituted naphthyridines and their use as syk kinase inhibitors |
| JP2014503488A (ja) * | 2010-11-12 | 2014-02-13 | バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー | プロパ−２−エン−１−アミンから出発して２，２−ジフルオロエチルアミンを調製する方法 |
| PH12014500209A1 (en) | 2011-07-26 | 2014-03-03 | Boehringer Ingelheim Int | Substituted quinolines and their use as medicaments |
| SG11201401937YA (en) | 2011-11-04 | 2014-05-29 | Hoffmann La Roche | New aryl-quinoline derivatives |
| ES2869275T3 (es) | 2015-04-24 | 2021-10-25 | Int Flavors & Fragrances Inc | Sistemas de suministro y procedimientos de preparación del mismo |
| US10226544B2 (en) | 2015-06-05 | 2019-03-12 | International Flavors & Fragrances Inc. | Malodor counteracting compositions |
| US20170204223A1 (en) | 2016-01-15 | 2017-07-20 | International Flavors & Fragrances Inc. | Polyalkoxy-polyimine adducts for use in delayed release of fragrance ingredients |
| CN108697591B (zh) | 2016-02-18 | 2022-06-17 | 国际香料和香精公司 | 聚脲胶囊组合物 |
| CN109414376A (zh) | 2016-07-01 | 2019-03-01 | 国际香料和香精公司 | 稳定的微胶囊组合物 |
| EP4209264A1 (en) | 2016-09-16 | 2023-07-12 | International Flavors & Fragrances Inc. | Microcapsule compositions stabilized with viscosity control agents |
| US20180085291A1 (en) | 2016-09-28 | 2018-03-29 | International Flavors & Fragrances Inc. | Microcapsule compositions containing amino silicone |
| US20180346648A1 (en) | 2017-05-30 | 2018-12-06 | International Flavors & Fragrances Inc. | Branched polyethyleneimine microcapsules |
| US12012394B2 (en) | 2018-02-19 | 2024-06-18 | Washington University | Alpha-synuclein ligands |
| CN112041361B (zh) | 2018-04-27 | 2023-06-30 | 国际香料和香精公司 | 稳定的聚脲微胶囊组合物 |
| WO2020131879A2 (en) | 2018-12-18 | 2020-06-25 | International Flavors & Fragrances Inc. | Protein microcapsules and method of preparing the same |
| BR112021011942A2 (pt) | 2018-12-18 | 2021-09-08 | International Flavors & Fragrances Inc. | Microcápsula, processo para preparar uma composição de microcápsula, composição de microcápsula, e, produto de consumo |
| US11946026B2 (en) | 2020-06-04 | 2024-04-02 | International Flavors & Fragrances Inc. | Fabric care composition and method for improving fragrance intensity with isopropyl myristate |
| EP3970690A3 (en) | 2020-06-05 | 2022-07-06 | International Flavors & Fragrances Inc. | Consumer products with improved aesthetics |
| US11873291B2 (en) | 2020-09-03 | 2024-01-16 | Immunesensor Therapeutics, Inc. | Quinoline cGAS antagonist compounds |
| EP4124383A1 (en) | 2021-07-27 | 2023-02-01 | International Flavors & Fragrances Inc. | Biodegradable microcapsules |
| EP4486734A1 (en) * | 2022-03-02 | 2025-01-08 | Immunesensor Therapeutics, Inc. | Quinoline cgas antagonist compounds |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4434086A (en) * | 1982-06-04 | 1984-02-28 | International Flavors & Fragrances, Inc. | Process for augmenting or enhancing the fresh air aroma of clothing |
| DE3911363B4 (de) * | 1989-04-07 | 2005-02-03 | Freytag Von Loringhoven, Andreas | Verfahren zur Herstellung von mit Duftstoffen anzureichernder Wasch- oder Spüllauge und Duftstoffzugabemittel zur Durchführung des Verfahrens |
| US20030104969A1 (en) * | 2000-05-11 | 2003-06-05 | Caswell Debra Sue | Laundry system having unitized dosing |
| US7053105B2 (en) | 2000-09-25 | 2006-05-30 | Janssen Pharmaceutica, N.V. | Farnesyl transferase inhibiting quinoline and quinazoline derivatives as farnesyl transferase inhibitors |
| CA2465978C (en) * | 2001-09-14 | 2015-04-07 | Soon Hyung Woo | Inhibitors of histone deacetylase |
| US6897220B2 (en) * | 2001-09-14 | 2005-05-24 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| AU2002352878B2 (en) * | 2001-11-27 | 2007-11-22 | Merck Sharp & Dohme Corp. | 2-Aminoquinoline compounds |
| MXPA05009722A (es) * | 2003-03-10 | 2006-03-09 | Schering Corp | Inhibidores heterociclicos de cinasa: metodos de uso y sintesis. |
| GB0309781D0 (en) | 2003-04-29 | 2003-06-04 | Glaxo Group Ltd | Compounds |
| WO2005037285A1 (en) * | 2003-10-16 | 2005-04-28 | Chiron Corporation | 2,6-disubstituted quinazolines, quinoxalines, quinolines and isoquinolines as inhibitors of raf kinase for treatment of cancer |
| DE102004008141A1 (de) * | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
| EP1861102A1 (en) * | 2005-03-15 | 2007-12-05 | F. Hoffmann-Roche AG | Use of 2-anilino-3,4-dihydro-quinazolines as 5ht5a receptor antagonists |
| JP4796624B2 (ja) * | 2005-05-04 | 2011-10-19 | エフ．ホフマン−ラ ロシュ アーゲー | ５−ｈｔ受容体に作用する（３，４−ジヒドロ−キナゾリン−２−イル）−（２−アリールオキシ−エチル）−アミン類 |
| ES2314940T3 (es) * | 2005-06-27 | 2009-03-16 | F. Hoffmann-La Roche Ag | Guanidinas sustituidas con cloro. |
| ATE472538T1 (de) * | 2005-06-27 | 2010-07-15 | Hoffmann La Roche | 8-alk0xy-4-methyl-3, 4-dihydr0-chinaz0lin-2-yl- amine und ihre verwendung als 5-ht5a-rezeptor- liganden |
| EP1917245A1 (de) * | 2005-08-21 | 2008-05-07 | Abbott GmbH & Co. KG | Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| WO2007022964A2 (de) * | 2005-08-24 | 2007-03-01 | Abbott Gmbh & Co. Kg | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| KR101088451B1 (ko) * | 2006-09-28 | 2011-12-01 | 에프. 호프만-라 로슈 아게 | 5-ｈｔ 결합 특성을 갖는 퀴놀린 유도체 |
| WO2009109477A1 (en) * | 2008-03-05 | 2009-09-11 | F. Hoffmann-La Roche Ag | 2-aminoquinolines |
| MX2010008239A (es) * | 2008-03-07 | 2010-08-18 | Hoffmann La Roche | 2-aminoquinolinas. |
| JP2011513452A (ja) * | 2008-03-12 | 2011-04-28 | エフ．ホフマン−ラ ロシュ アーゲー | ５−ｈｔ５ａ受容体アンタゴニストとしての２−アミノキノリン |
-
2008
- 2008-09-18 WO PCT/EP2008/062416 patent/WO2009040290A1/en not_active Ceased
- 2008-09-18 KR KR1020107006399A patent/KR101192952B1/ko not_active Expired - Fee Related
- 2008-09-18 BR BRPI0817245-5A patent/BRPI0817245A2/pt not_active IP Right Cessation
- 2008-09-18 EP EP08804358A patent/EP2195296A1/en not_active Withdrawn
- 2008-09-18 MX MX2010003001A patent/MX2010003001A/es active IP Right Grant
- 2008-09-18 AU AU2008303602A patent/AU2008303602A1/en not_active Abandoned
- 2008-09-18 JP JP2010526250A patent/JP2010540483A/ja active Pending
- 2008-09-18 CN CN2008801088436A patent/CN101808999B/zh not_active Expired - Fee Related
- 2008-09-18 CA CA2699697A patent/CA2699697A1/en not_active Abandoned
- 2008-09-19 US US12/233,625 patent/US20090088451A1/en not_active Abandoned
- 2008-09-25 AR ARP080104159A patent/AR068547A1/es unknown
- 2008-09-25 PE PE2008001671A patent/PE20091204A1/es not_active Application Discontinuation
- 2008-09-26 CL CL2008002864A patent/CL2008002864A1/es unknown
- 2008-09-26 TW TW097137404A patent/TW200922580A/zh unknown
-
2012
- 2012-01-27 US US13/359,933 patent/US8399674B2/en not_active Expired - Fee Related
-
2013
- 2013-09-10 US US14/022,712 patent/US20140107010A1/en not_active Abandoned
-
2016
- 2016-03-01 US US15/057,922 patent/US20170015952A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR068547A1 (es) | 2009-11-18 |
| PE20091204A1 (es) | 2009-08-26 |
| KR20100047326A (ko) | 2010-05-07 |
| CA2699697A1 (en) | 2009-04-02 |
| KR101192952B1 (ko) | 2012-10-18 |
| EP2195296A1 (en) | 2010-06-16 |
| US20090088451A1 (en) | 2009-04-02 |
| US20140107010A1 (en) | 2014-04-17 |
| MX2010003001A (es) | 2010-04-01 |
| CL2008002864A1 (es) | 2009-08-21 |
| AU2008303602A1 (en) | 2009-04-02 |
| JP2010540483A (ja) | 2010-12-24 |
| US20170015952A1 (en) | 2017-01-19 |
| CN101808999B (zh) | 2013-02-13 |
| US20120136018A1 (en) | 2012-05-31 |
| US8399674B2 (en) | 2013-03-19 |
| TW200922580A (en) | 2009-06-01 |
| CN101808999A (zh) | 2010-08-18 |
| WO2009040290A1 (en) | 2009-04-02 |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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