BRPI0817245A2 - Derivados e quinolina como antagonistas receptores de 5ht5a - Google Patents
Derivados e quinolina como antagonistas receptores de 5ht5aInfo
- Publication number
- BRPI0817245A2 BRPI0817245A2 BRPI0817245-5A BRPI0817245A BRPI0817245A2 BR PI0817245 A2 BRPI0817245 A2 BR PI0817245A2 BR PI0817245 A BRPI0817245 A BR PI0817245A BR PI0817245 A2 BRPI0817245 A2 BR PI0817245A2
- Authority
- BR
- Brazil
- Prior art keywords
- quinoline
- derivatives
- receptor antagonists
- 5ht5a
- 5ht5a receptor
- Prior art date
Links
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 title 2
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 108010006590 serotonin 5 receptor Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/0047—Detergents in the form of bars or tablets
- C11D17/0065—Solid detergents containing builders
- C11D17/0073—Tablets
- C11D17/0086—Laundry tablets
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/001—Softening compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/50—Perfumes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/50—Perfumes
- C11D3/502—Protected perfumes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D2111/00—Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
- C11D2111/10—Objects to be cleaned
- C11D2111/12—Soft surfaces, e.g. textile
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Detergent Compositions (AREA)
- Quinoline Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07117420 | 2007-09-27 | ||
| PCT/EP2008/062416 WO2009040290A1 (en) | 2007-09-27 | 2008-09-18 | Quinoline derivatives as 5ht5a receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0817245A2 true BRPI0817245A2 (pt) | 2015-06-16 |
Family
ID=40336429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0817245-5A BRPI0817245A2 (pt) | 2007-09-27 | 2008-09-18 | Derivados e quinolina como antagonistas receptores de 5ht5a |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20090088451A1 (pt) |
| EP (1) | EP2195296A1 (pt) |
| JP (1) | JP2010540483A (pt) |
| KR (1) | KR101192952B1 (pt) |
| CN (1) | CN101808999B (pt) |
| AR (1) | AR068547A1 (pt) |
| AU (1) | AU2008303602A1 (pt) |
| BR (1) | BRPI0817245A2 (pt) |
| CA (1) | CA2699697A1 (pt) |
| CL (1) | CL2008002864A1 (pt) |
| MX (1) | MX2010003001A (pt) |
| PE (1) | PE20091204A1 (pt) |
| TW (1) | TW200922580A (pt) |
| WO (1) | WO2009040290A1 (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2262789A1 (en) * | 2008-03-05 | 2010-12-22 | F. Hoffmann-La Roche AG | 2-aminoquinolines |
| CA2711247A1 (en) * | 2008-03-07 | 2009-09-11 | F. Hoffmann-La Roche Ag | 2-aminoquinolines |
| WO2009112395A1 (en) * | 2008-03-12 | 2009-09-17 | F. Hoffmann-La Roche Ag | 2-aminoquinolines as 5-ht5a receptor antagonists |
| TW201116281A (en) | 2009-08-06 | 2011-05-16 | Astellas Pharma Inc | N atom containing ring acylguanidine derivatives |
| NZ600857A (en) | 2010-01-29 | 2014-06-27 | Boehringer Ingelheim Int | Substituted naphthyridines and their use as syk kinase inhibitors |
| KR20130101111A (ko) * | 2010-11-12 | 2013-09-12 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 프로프-2-엔-1-아민으로부터 2,2-디플루오로에틸아민의 제조방법 |
| CN103827090B (zh) | 2011-07-26 | 2016-04-20 | 勃林格殷格翰国际有限公司 | 取代的喹啉及其作为药物的用途 |
| KR20140088194A (ko) | 2011-11-04 | 2014-07-09 | 에프. 호프만-라 로슈 아게 | 아릴-퀴놀린 유도체 |
| CN107708429A (zh) | 2015-04-24 | 2018-02-16 | 国际香料和香精公司 | 递送体系及其制备方法 |
| US10226544B2 (en) | 2015-06-05 | 2019-03-12 | International Flavors & Fragrances Inc. | Malodor counteracting compositions |
| US20170204223A1 (en) | 2016-01-15 | 2017-07-20 | International Flavors & Fragrances Inc. | Polyalkoxy-polyimine adducts for use in delayed release of fragrance ingredients |
| WO2017143174A1 (en) | 2016-02-18 | 2017-08-24 | International Flavors & Fragrances Inc. | Polyurea capsule compositions |
| US11540985B2 (en) | 2016-07-01 | 2023-01-03 | International Flavors & Fragrances Inc. | Stable microcapsule compositions |
| ES2950434T3 (es) | 2016-09-16 | 2023-10-10 | Int Flavors & Fragrances Inc | Composiciones de microcápsula estabilizadas con agentes de control de la viscosidad |
| US20180085291A1 (en) | 2016-09-28 | 2018-03-29 | International Flavors & Fragrances Inc. | Microcapsule compositions containing amino silicone |
| US20180346648A1 (en) | 2017-05-30 | 2018-12-06 | International Flavors & Fragrances Inc. | Branched polyethyleneimine microcapsules |
| US12012394B2 (en) | 2018-02-19 | 2024-06-18 | Washington University | Alpha-synuclein ligands |
| BR112020021814B1 (pt) | 2018-04-27 | 2023-10-10 | International Flavors & Fragrances Inc | Composição de microcápsula, métodos para preparar uma composição de microcápsula e para conferir uma sensação de limpeza e frescor a um produto de tecido ou um produto de cuidados com os cabelos, e, produto de consumo |
| EP3897524A4 (en) | 2018-12-18 | 2023-04-26 | International Flavors & Fragrances Inc. | PROTEIN MICROCAPSULES AND PROCESS FOR THE PRODUCTION THEREOF |
| EP3897521A4 (en) | 2018-12-18 | 2023-01-25 | International Flavors & Fragrances Inc. | GUARGUM MICROCAPSULES |
| US11946026B2 (en) | 2020-06-04 | 2024-04-02 | International Flavors & Fragrances Inc. | Fabric care composition and method for improving fragrance intensity with isopropyl myristate |
| EP3970690A3 (en) | 2020-06-05 | 2022-07-06 | International Flavors & Fragrances Inc. | Consumer products with improved aesthetics |
| KR20230062845A (ko) | 2020-09-03 | 2023-05-09 | 이뮨센서 테라퓨틱스, 인코포레이티드 | 퀴놀린 cgas 길항제 화합물 |
| EP4124383A1 (en) | 2021-07-27 | 2023-02-01 | International Flavors & Fragrances Inc. | Biodegradable microcapsules |
| CN119137112A (zh) * | 2022-03-02 | 2024-12-13 | 免疫传感器治疗股份有限公司 | 喹啉cGAS拮抗剂化合物 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4434086A (en) * | 1982-06-04 | 1984-02-28 | International Flavors & Fragrances, Inc. | Process for augmenting or enhancing the fresh air aroma of clothing |
| DE3911363B4 (de) * | 1989-04-07 | 2005-02-03 | Freytag Von Loringhoven, Andreas | Verfahren zur Herstellung von mit Duftstoffen anzureichernder Wasch- oder Spüllauge und Duftstoffzugabemittel zur Durchführung des Verfahrens |
| US20030104969A1 (en) * | 2000-05-11 | 2003-06-05 | Caswell Debra Sue | Laundry system having unitized dosing |
| DE60118225T2 (de) * | 2000-09-25 | 2007-05-03 | Janssen Pharmaceutica N.V. | Chinolin- und chinazolinderivate und deren verwendung als farnesyl transferase inhibitoren |
| EP1429765A2 (en) * | 2001-09-14 | 2004-06-23 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| US6897220B2 (en) * | 2001-09-14 | 2005-05-24 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| CA2468015A1 (en) * | 2001-11-27 | 2003-06-05 | Merck & Co., Inc. | 2-aminoquinoline compounds |
| MXPA05009722A (es) * | 2003-03-10 | 2006-03-09 | Schering Corp | Inhibidores heterociclicos de cinasa: metodos de uso y sintesis. |
| GB0309781D0 (en) | 2003-04-29 | 2003-06-04 | Glaxo Group Ltd | Compounds |
| CN1882345A (zh) * | 2003-10-16 | 2006-12-20 | 希龙公司 | 作为raf激酶抑制剂以治疗癌症的2,6-二取代的喹唑啉、喹喔啉、喹啉和异喹啉 |
| DE102004008141A1 (de) | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
| JP4774436B2 (ja) * | 2005-03-15 | 2011-09-14 | エフ.ホフマン−ラ ロシュ アーゲー | 5ht5aレセプターアンタゴニストとしての2−アニリノ−3,4−ジヒドロ−キナゾリンの使用 |
| ATE449082T1 (de) * | 2005-05-04 | 2009-12-15 | Hoffmann La Roche | (3,4-dihydro-chinazolin-2-yl)-(2-aryloxy-ethyl) amine mit aktivität am 5-ht-rezeptor |
| ES2314940T3 (es) * | 2005-06-27 | 2009-03-16 | F. Hoffmann-La Roche Ag | Guanidinas sustituidas con cloro. |
| ATE472538T1 (de) * | 2005-06-27 | 2010-07-15 | Hoffmann La Roche | 8-alk0xy-4-methyl-3, 4-dihydr0-chinaz0lin-2-yl- amine und ihre verwendung als 5-ht5a-rezeptor- liganden |
| WO2007022946A1 (de) * | 2005-08-21 | 2007-03-01 | Abbott Gmbh & Co. Kg | Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| EP1917244A2 (de) * | 2005-08-24 | 2008-05-07 | Abbott GmbH & Co. KG | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| MX2009003170A (es) * | 2006-09-28 | 2009-04-03 | Hoffmann La Roche | Derivados de quinolina con propiedades de union a 5-hidroxitriptamina (5-ht). |
| EP2262789A1 (en) * | 2008-03-05 | 2010-12-22 | F. Hoffmann-La Roche AG | 2-aminoquinolines |
| CA2711247A1 (en) * | 2008-03-07 | 2009-09-11 | F. Hoffmann-La Roche Ag | 2-aminoquinolines |
| WO2009112395A1 (en) * | 2008-03-12 | 2009-09-17 | F. Hoffmann-La Roche Ag | 2-aminoquinolines as 5-ht5a receptor antagonists |
-
2008
- 2008-09-18 AU AU2008303602A patent/AU2008303602A1/en not_active Abandoned
- 2008-09-18 CA CA2699697A patent/CA2699697A1/en not_active Abandoned
- 2008-09-18 KR KR1020107006399A patent/KR101192952B1/ko not_active Expired - Fee Related
- 2008-09-18 MX MX2010003001A patent/MX2010003001A/es active IP Right Grant
- 2008-09-18 JP JP2010526250A patent/JP2010540483A/ja active Pending
- 2008-09-18 WO PCT/EP2008/062416 patent/WO2009040290A1/en not_active Ceased
- 2008-09-18 BR BRPI0817245-5A patent/BRPI0817245A2/pt not_active IP Right Cessation
- 2008-09-18 EP EP08804358A patent/EP2195296A1/en not_active Withdrawn
- 2008-09-18 CN CN2008801088436A patent/CN101808999B/zh not_active Expired - Fee Related
- 2008-09-19 US US12/233,625 patent/US20090088451A1/en not_active Abandoned
- 2008-09-25 AR ARP080104159A patent/AR068547A1/es unknown
- 2008-09-25 PE PE2008001671A patent/PE20091204A1/es not_active Application Discontinuation
- 2008-09-26 CL CL2008002864A patent/CL2008002864A1/es unknown
- 2008-09-26 TW TW097137404A patent/TW200922580A/zh unknown
-
2012
- 2012-01-27 US US13/359,933 patent/US8399674B2/en not_active Expired - Fee Related
-
2013
- 2013-09-10 US US14/022,712 patent/US20140107010A1/en not_active Abandoned
-
2016
- 2016-03-01 US US15/057,922 patent/US20170015952A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2195296A1 (en) | 2010-06-16 |
| US20140107010A1 (en) | 2014-04-17 |
| MX2010003001A (es) | 2010-04-01 |
| PE20091204A1 (es) | 2009-08-26 |
| JP2010540483A (ja) | 2010-12-24 |
| TW200922580A (en) | 2009-06-01 |
| KR101192952B1 (ko) | 2012-10-18 |
| CL2008002864A1 (es) | 2009-08-21 |
| WO2009040290A1 (en) | 2009-04-02 |
| KR20100047326A (ko) | 2010-05-07 |
| US8399674B2 (en) | 2013-03-19 |
| AU2008303602A1 (en) | 2009-04-02 |
| US20120136018A1 (en) | 2012-05-31 |
| US20090088451A1 (en) | 2009-04-02 |
| CN101808999A (zh) | 2010-08-18 |
| CN101808999B (zh) | 2013-02-13 |
| CA2699697A1 (en) | 2009-04-02 |
| US20170015952A1 (en) | 2017-01-19 |
| AR068547A1 (es) | 2009-11-18 |
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