BRPI0913452A2 - células aderentes provenientes do tecido placentário e seu uso em terapia - Google Patents
células aderentes provenientes do tecido placentário e seu uso em terapiaInfo
- Publication number
- BRPI0913452A2 BRPI0913452A2 BRPI0913452A BRPI0913452A BRPI0913452A2 BR PI0913452 A2 BRPI0913452 A2 BR PI0913452A2 BR PI0913452 A BRPI0913452 A BR PI0913452A BR PI0913452 A BRPI0913452 A BR PI0913452A BR PI0913452 A2 BRPI0913452 A2 BR PI0913452A2
- Authority
- BR
- Brazil
- Prior art keywords
- therapy
- adherent cells
- placental tissue
- placental
- tissue
- Prior art date
Links
- 230000001464 adherent effect Effects 0.000 title 1
- 210000005059 placental tissue Anatomy 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/34—Sugars
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Gynecology & Obstetrics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13637508P | 2008-09-02 | 2008-09-02 | |
| US20205009P | 2009-01-23 | 2009-01-23 | |
| PCT/IL2009/000846 WO2010026575A2 (en) | 2008-09-02 | 2009-09-01 | Adherent cells from placenta tissue and use thereof in therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0913452A2 true BRPI0913452A2 (pt) | 2015-12-01 |
Family
ID=41507797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0913452A BRPI0913452A2 (pt) | 2008-09-02 | 2009-09-01 | células aderentes provenientes do tecido placentário e seu uso em terapia |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8524496B2 (pt) |
| EP (2) | EP2334783B1 (pt) |
| CN (2) | CN102282249A (pt) |
| AU (1) | AU2009288781B2 (pt) |
| BR (1) | BRPI0913452A2 (pt) |
| CA (1) | CA2735790C (pt) |
| HK (1) | HK1222326A1 (pt) |
| IL (1) | IL211525A (pt) |
| MX (1) | MX2011002328A (pt) |
| RU (1) | RU2539786C2 (pt) |
| SG (1) | SG190659A1 (pt) |
| WO (1) | WO2010026575A2 (pt) |
Families Citing this family (43)
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|---|---|---|---|---|
| KR20140107677A (ko) | 2007-09-19 | 2014-09-04 | 플루리스템 리미티드 | 지방 또는 태반 조직 유래의 부착 세포 및 이의 치료 용도 |
| WO2009144720A1 (en) | 2008-05-27 | 2009-12-03 | Pluristem Ltd. | Methods of treating inflammatory colon diseases |
| MX2011002328A (es) | 2008-09-02 | 2011-05-19 | Pluristem Ltd | Celulas adherentes del tejido de placenta y su uso en terapia. |
| ES2553712T3 (es) | 2009-11-30 | 2015-12-11 | Pluristem Ltd. | Células adherentes de la placenta y uso de las mismas en el tratamiento de enfermedad |
| SI2556145T1 (sl) * | 2010-04-07 | 2017-01-31 | Anthrogenesis Corporation | Angiogeneza z uporabo placentnih matičnih celic |
| EP2575831B1 (en) | 2010-05-27 | 2016-04-20 | Pluristem Ltd. | Skeletal muscle regeneration using mesenchymal stem cells |
| WO2012048275A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| EP3260533B1 (en) | 2011-03-22 | 2019-09-11 | Pluristem Ltd. | Methods for treating radiation or chemical injury |
| MX349171B (es) | 2011-04-15 | 2017-07-17 | Pluristem Ltd | Metodos y sistemas para cosechar celulas. |
| CN102586184B (zh) * | 2011-09-05 | 2013-10-23 | 博雅干细胞科技有限公司 | 建立胎盘间充质干细胞库的方法 |
| US20130142762A1 (en) | 2011-11-07 | 2013-06-06 | Hina W. Chaudhry | Methods of cardiac repair |
| SG11201501065QA (en) | 2012-09-04 | 2015-03-30 | Pluristem Ltd | Methods for prevention and treatment of preeclampsia |
| US9512393B2 (en) | 2012-09-06 | 2016-12-06 | Pluristem Ltd. | Devices and methods for culture of cells |
| WO2014128634A1 (en) * | 2013-02-20 | 2014-08-28 | Pluristem Ltd. | Gene and protein expression properties of adherent stromal cells cultured in 3d |
| WO2015004609A2 (en) * | 2013-07-09 | 2015-01-15 | Pluristem Ltd. | Adherent cells from placenta and use thereof in treatment of injured tendons |
| CN105793411B (zh) | 2013-11-16 | 2018-04-17 | 泰尔茂比司特公司 | 生物反应器中的细胞扩增 |
| US10392593B2 (en) | 2014-03-04 | 2019-08-27 | Pluristem Ltd. | Systems and methods for growing and harvesting cells |
| JP6783143B2 (ja) | 2014-03-25 | 2020-11-11 | テルモ ビーシーティー、インコーポレーテッド | 培地の受動的補充 |
| JP2017529101A (ja) * | 2014-09-18 | 2017-10-05 | ナショナル ヘルス リサーチ インスティテュートス | 前駆細胞、それらの調製方法およびそれらの使用 |
| US20160090569A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled Feed |
| DK3204022T3 (da) | 2014-10-09 | 2021-03-08 | Celularity Inc | Placenta-afledte adhærente celle-exosomer og anvendelser deraf |
| CN107864627A (zh) | 2015-03-23 | 2018-03-30 | 普拉里斯坦有限公司 | 包含粘附基质细胞的方法和组合物 |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CA3012741A1 (en) * | 2016-02-18 | 2017-08-24 | Pluristem Ltd. | Methods and compositions for treating cancer and neoplasms |
| US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
| CN109496236A (zh) * | 2016-06-06 | 2019-03-19 | 普拉里斯坦有限公司 | 改变的粘附基质细胞及其产生和使用方法 |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| US11629332B2 (en) | 2017-03-31 | 2023-04-18 | Terumo Bct, Inc. | Cell expansion |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| WO2018185584A1 (en) * | 2017-04-05 | 2018-10-11 | Pluristem Ltd. | Methods and compositions for treating acute lung injury and respiratory distress syndrome |
| WO2018198012A1 (en) | 2017-04-24 | 2018-11-01 | Pluristem Ltd. | Methods and compositions for treating neurological disorders |
| RU2672318C1 (ru) * | 2017-09-19 | 2018-11-13 | Общество с ограниченной ответственностью "Международный Биотехнологический Центр "Генериум" | Способ получения моноклональных антител терапевтического назначения с помощью непрерывного культивирования клеток сно |
| CN111727238B (zh) * | 2017-10-27 | 2024-06-25 | 阿里斯制药有限公司 | 非人动物胎儿组织提取物、生产提取物的方法及其用途 |
| JP7526001B2 (ja) * | 2017-12-28 | 2024-07-31 | 株式会社カネカ | 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物 |
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| CN113151162A (zh) * | 2021-04-13 | 2021-07-23 | 广东唯泰生物科技有限公司 | 外泌体在促进壁蜕膜间充质干细胞生长中的应用 |
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| CN114854666A (zh) * | 2022-06-02 | 2022-08-05 | 深圳大学 | 无支架组织结构的制作方法 |
| CN115322964B (zh) * | 2022-08-18 | 2024-05-14 | 宁波希诺赛生物科技有限公司 | 一种3d培养羊膜间充质干细胞种子库构建方法 |
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2009
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- 2009-09-01 EP EP09737162.9A patent/EP2334783B1/en active Active
- 2009-09-01 US US13/061,538 patent/US8524496B2/en active Active
- 2009-09-01 BR BRPI0913452A patent/BRPI0913452A2/pt not_active IP Right Cessation
- 2009-09-01 CN CN2009801437713A patent/CN102282249A/zh active Pending
- 2009-09-01 SG SG2013037817A patent/SG190659A1/en unknown
- 2009-09-01 RU RU2011111938/10A patent/RU2539786C2/ru active
- 2009-09-01 WO PCT/IL2009/000846 patent/WO2010026575A2/en not_active Ceased
- 2009-09-01 CN CN201610165728.9A patent/CN105708862B/zh active Active
- 2009-09-01 EP EP16174887.6A patent/EP3115451A1/en not_active Withdrawn
- 2009-09-01 CA CA2735790A patent/CA2735790C/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3115451A1 (en) | 2017-01-11 |
| EP2334783B1 (en) | 2016-06-22 |
| AU2009288781B2 (en) | 2015-01-29 |
| HK1222326A1 (zh) | 2017-06-30 |
| CN105708862A (zh) | 2016-06-29 |
| EP2334783A2 (en) | 2011-06-22 |
| AU2009288781A1 (en) | 2010-03-11 |
| CN102282249A (zh) | 2011-12-14 |
| SG190659A1 (en) | 2013-06-28 |
| US20130337558A1 (en) | 2013-12-19 |
| RU2539786C2 (ru) | 2015-01-27 |
| US8524496B2 (en) | 2013-09-03 |
| CA2735790C (en) | 2017-02-28 |
| CN105708862B (zh) | 2020-11-06 |
| WO2010026575A2 (en) | 2010-03-11 |
| US20110256159A1 (en) | 2011-10-20 |
| AU2009288781A2 (en) | 2011-04-21 |
| MX2011002328A (es) | 2011-05-19 |
| HK1153234A1 (zh) | 2012-03-23 |
| WO2010026575A3 (en) | 2010-09-02 |
| CA2735790A1 (en) | 2010-03-11 |
| IL211525A (en) | 2016-11-30 |
| RU2011111938A (ru) | 2012-10-10 |
| US9758762B2 (en) | 2017-09-12 |
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