BRPI0913475A2 - Molécula de ácido nucleico, vetor, célula, método para proteção de uma célula, métodos para expressão de uma proteína de interesse, método para adição ou intensificação da adaptabilidade ou resistência de uma célula e kit - Google Patents

Molécula de ácido nucleico, vetor, célula, método para proteção de uma célula, métodos para expressão de uma proteína de interesse, método para adição ou intensificação da adaptabilidade ou resistência de uma célula e kit

Info

Publication number
BRPI0913475A2
BRPI0913475A2 BRPI0913475-1A BRPI0913475A BRPI0913475A2 BR PI0913475 A2 BRPI0913475 A2 BR PI0913475A2 BR PI0913475 A BRPI0913475 A BR PI0913475A BR PI0913475 A2 BRPI0913475 A2 BR PI0913475A2
Authority
BR
Brazil
Prior art keywords
cell
expressing
kit
protecting
vector
Prior art date
Application number
BRPI0913475-1A
Other languages
English (en)
Inventor
Laetitia Malphettes
Andrew Snowden
Inn H Yuk
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BRPI0913475A2 publication Critical patent/BRPI0913475A2/pt
Publication of BRPI0913475B1 publication Critical patent/BRPI0913475B1/pt
Publication of BRPI0913475B8 publication Critical patent/BRPI0913475B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
BRPI0913475A 2008-09-15 2009-09-15 vetor BRPI0913475B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9714908P 2008-09-15 2008-09-15
US61/097,149 2008-09-15
PCT/US2009/057031 WO2010031074A2 (en) 2008-09-15 2009-09-15 Compositions and methods for regulating cell osmolarity

Publications (3)

Publication Number Publication Date
BRPI0913475A2 true BRPI0913475A2 (pt) 2015-08-04
BRPI0913475B1 BRPI0913475B1 (pt) 2019-04-16
BRPI0913475B8 BRPI0913475B8 (pt) 2019-05-07

Family

ID=42005828

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0913475A BRPI0913475B8 (pt) 2008-09-15 2009-09-15 vetor

Country Status (16)

Country Link
US (3) US20110269233A1 (pt)
EP (1) EP2326720B1 (pt)
JP (4) JP5524214B2 (pt)
KR (5) KR20150126739A (pt)
CN (2) CN102216459A (pt)
AU (1) AU2009290563A1 (pt)
BR (1) BRPI0913475B8 (pt)
CA (1) CA2734922C (pt)
ES (1) ES2670368T3 (pt)
HK (1) HK1199906A1 (pt)
HR (1) HRP20180738T1 (pt)
IL (1) IL211368B (pt)
MX (2) MX347112B (pt)
PL (1) PL2326720T3 (pt)
SI (1) SI2326720T1 (pt)
WO (1) WO2010031074A2 (pt)

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Also Published As

Publication number Publication date
CA2734922A1 (en) 2010-03-18
JP6797151B2 (ja) 2020-12-09
EP2326720A4 (en) 2012-04-18
US20150307888A1 (en) 2015-10-29
CN103937797A (zh) 2014-07-23
KR20160104105A (ko) 2016-09-02
KR102018475B1 (ko) 2019-09-04
KR20180085055A (ko) 2018-07-25
BRPI0913475B1 (pt) 2019-04-16
CA2734922C (en) 2020-01-14
HRP20180738T1 (hr) 2018-06-15
US20190127741A1 (en) 2019-05-02
PL2326720T3 (pl) 2018-08-31
MX2011002638A (es) 2011-04-05
JP2012502630A (ja) 2012-02-02
SI2326720T1 (en) 2018-06-29
US11279939B2 (en) 2022-03-22
AU2009290563A1 (en) 2010-03-18
KR20130099255A (ko) 2013-09-05
JP5809314B2 (ja) 2015-11-10
MX347112B (es) 2017-04-12
CN102216459A (zh) 2011-10-12
KR20110056323A (ko) 2011-05-26
IL211368A0 (en) 2011-04-28
EP2326720B1 (en) 2018-03-21
CN103937797B (zh) 2021-09-21
EP2326720A2 (en) 2011-06-01
WO2010031074A3 (en) 2010-07-01
JP5524214B2 (ja) 2014-06-18
JP2014168470A (ja) 2014-09-18
JP2016028585A (ja) 2016-03-03
JP6342863B2 (ja) 2018-06-13
KR20150126739A (ko) 2015-11-12
JP2018157825A (ja) 2018-10-11
HK1199906A1 (en) 2015-07-24
BRPI0913475B8 (pt) 2019-05-07
IL211368B (en) 2021-12-01
ES2670368T3 (es) 2018-05-30
WO2010031074A2 (en) 2010-03-18
US20110269233A1 (en) 2011-11-03
US10100319B2 (en) 2018-10-16
KR101880919B1 (ko) 2018-07-24

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