BRPI0913680A2 - "célula bacteriana ácido-láctica, método para aumentar a atividade de um polipeptídeo dihidroxi-ácido desidratase heterólogo em uma célula bacteriana ácido-láctica e método de produção de insobutanol" - Google Patents

"célula bacteriana ácido-láctica, método para aumentar a atividade de um polipeptídeo dihidroxi-ácido desidratase heterólogo em uma célula bacteriana ácido-láctica e método de produção de insobutanol"

Info

Publication number
BRPI0913680A2
BRPI0913680A2 BRPI0913680A BRPI0913680A BRPI0913680A2 BR PI0913680 A2 BRPI0913680 A2 BR PI0913680A2 BR PI0913680 A BRPI0913680 A BR PI0913680A BR PI0913680 A BRPI0913680 A BR PI0913680A BR PI0913680 A2 BRPI0913680 A2 BR PI0913680A2
Authority
BR
Brazil
Prior art keywords
bacterial cell
lactic acid
acid bacterial
insobutanol
heterologous
Prior art date
Application number
BRPI0913680A
Other languages
English (en)
Inventor
James Paul Brian
Suh Wonchul
Original Assignee
Butamax Advanced Biofuels Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Butamax Advanced Biofuels Llc filed Critical Butamax Advanced Biofuels Llc
Publication of BRPI0913680A2 publication Critical patent/BRPI0913680A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
BRPI0913680A 2008-09-29 2009-09-29 "célula bacteriana ácido-láctica, método para aumentar a atividade de um polipeptídeo dihidroxi-ácido desidratase heterólogo em uma célula bacteriana ácido-láctica e método de produção de insobutanol" BRPI0913680A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10080908P 2008-09-29 2008-09-29
PCT/US2009/058843 WO2010037119A1 (en) 2008-09-29 2009-09-29 Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria

Publications (1)

Publication Number Publication Date
BRPI0913680A2 true BRPI0913680A2 (pt) 2019-09-24

Family

ID=41360282

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0913680A BRPI0913680A2 (pt) 2008-09-29 2009-09-29 "célula bacteriana ácido-láctica, método para aumentar a atividade de um polipeptídeo dihidroxi-ácido desidratase heterólogo em uma célula bacteriana ácido-láctica e método de produção de insobutanol"

Country Status (6)

Country Link
US (1) US20100081182A1 (pt)
EP (1) EP2342330A1 (pt)
AU (1) AU2009296232A1 (pt)
BR (1) BRPI0913680A2 (pt)
CA (1) CA2735022A1 (pt)
WO (1) WO2010037119A1 (pt)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1948814B1 (en) 2005-10-26 2018-11-21 Butamax (TM) Advanced Biofuels LLC Fermentive production of four carbon alcohols
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
NZ579780A (en) 2007-04-18 2012-07-27 Butamax Advanced Biofuels Llc Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US8188250B2 (en) 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
CA2735690A1 (en) 2008-09-29 2010-04-01 Dennis Flint Identification and use of bacterial [2fe-2s] dihydroxy-acid dehydratases
AU2009296218A1 (en) * 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria
CN102186983A (zh) 2008-09-29 2011-09-14 布特马斯先进生物燃料有限责任公司 酵母中提高的异源Fe-S酶活性
CA2735948A1 (en) * 2008-09-29 2011-04-01 Butamaxtm Advanced Biofuels Llc Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
CA2770842A1 (en) * 2009-08-12 2011-02-17 Gevo, Inc. Cytosolic isobutanol pathway localization for the production of isobutanol
CA2775892A1 (en) 2009-09-29 2011-04-07 Butamax(Tm) Advanced Biofuels Llc Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes
EP2483400A1 (en) * 2009-09-29 2012-08-08 Butamax(tm) Advanced Biofuels LLC Improved flux to acetolactate-derived products in lactic acid bacteria
GB2487889B (en) 2009-11-24 2012-12-19 Gevo Inc Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
MX2012007583A (es) 2009-12-29 2012-07-30 Butamax Tm Advanced Biofuels Alcohol deshidrogenasas (adh) utiles para la produccion fermentativa de alcoholes alquilicos de cadena corta.
CN102782119B (zh) 2010-02-17 2016-03-16 布特马斯先进生物燃料有限责任公司 改善需Fe-S簇蛋白质的活性
NZ707800A (en) 2010-09-07 2016-09-30 Butamax Tm Advanced Biofuels Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
WO2012071121A1 (en) * 2010-11-24 2012-05-31 Gevo, Inc. Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
EP2689014B1 (en) 2011-03-24 2019-04-24 Butamax (TM) Advanced Biofuels LLC Host cells and methods for production of isobutanol
CA2834379A1 (en) 2011-04-29 2012-11-01 The Goodyear Tire & Rubber Company Production of mevalonate, isoprene, and isoprenoids using genes encoding polypeptides having thiolase, hmg-coa synthase and hmg-coa reductase enzymatic activities
CN105473726B (zh) 2011-07-28 2021-03-12 布特马斯先进生物燃料有限责任公司 酮异戊酸脱羧酶及其使用方法
WO2013043801A1 (en) * 2011-09-20 2013-03-28 Gevo, Inc. High-performance dihydroxy acid dehydratases
US9909148B2 (en) 2011-12-30 2018-03-06 Butamax Advanced Biofuels Llc Fermentative production of alcohols
CN102586305A (zh) * 2012-02-29 2012-07-18 山东大学 哈氏噬纤维菌的电转化方法
KR20140146616A (ko) 2012-03-23 2014-12-26 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 부타놀로겐용 배지의 아세테이트 보충물
MX2014013446A (es) 2012-05-11 2014-12-08 Butamax Advanced Biofuels Llc Enzimas de cetol-acido reductoisomerasa y metodos de uso.
BR112015003701A2 (pt) 2012-08-22 2017-12-12 Butamax Advanced Biofuels Llc células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição
WO2014047421A1 (en) 2012-09-21 2014-03-27 Butamax(Tm) Advanced Biofuels Llc Production of renewable hydrocarbon compositions
AU2013323427A1 (en) 2012-09-26 2015-03-05 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
WO2014106107A2 (en) 2012-12-28 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Dhad variants for butanol production
ES2735024T3 (es) 2013-03-14 2019-12-13 Du Pont Glicerol-3-fosfato deshidrogenasa para la producción de butanol
US9580705B2 (en) 2013-03-15 2017-02-28 Butamax Advanced Biofuels Llc DHAD variants and methods of screening
WO2014144210A2 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
CA2957920A1 (en) 2014-08-11 2016-02-18 Butamax Advanced Biofuels Llc Yeast preparations and methods of making the same
US10556930B2 (en) 2015-12-16 2020-02-11 Washington University Host cells and methods for producing fatty acid-derivatives with high branched-chain percentage
KR102171363B1 (ko) * 2019-02-25 2020-10-28 아주대학교산학협력단 전구세포 또는 줄기세포 동원 활성을 가지는 물질 p 유사체 및 이를 포함하는 조성물
US11905544B2 (en) 2020-12-17 2024-02-20 Debut Biotechnology, Inc. Dehydratase variants with improved specific activity for the production of pyruvate from glycerate
US12006528B2 (en) 2020-12-18 2024-06-11 Debut Biotechnology, Inc. Cell-free production of geranyl pyrophosphate from glycerol in a cell-free manufacturing system
IL307636A (en) 2021-04-13 2023-12-01 Debut Biotechnology Inc Bioproduction of flavonoids and anthocyanin using microbial hosts
DE102022119024A1 (de) * 2022-07-28 2024-02-08 INM - Leibniz-Institut für Neue Materialien gemeinnützige Gesellschaft mit beschränkter Haftung Neuartige genetische Werkzeuge

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1948814B1 (en) * 2005-10-26 2018-11-21 Butamax (TM) Advanced Biofuels LLC Fermentive production of four carbon alcohols
EP2118266A4 (en) * 2007-02-09 2010-05-19 Univ California BIOFUEL PRODUCTION BY RECOMBINANT MICROORGANISMS
CN102782119B (zh) * 2010-02-17 2016-03-16 布特马斯先进生物燃料有限责任公司 改善需Fe-S簇蛋白质的活性

Also Published As

Publication number Publication date
WO2010037119A1 (en) 2010-04-01
US20100081182A1 (en) 2010-04-01
EP2342330A1 (en) 2011-07-13
AU2009296232A1 (en) 2010-04-01
CA2735022A1 (en) 2010-04-01

Similar Documents

Publication Publication Date Title
BR112012002137A2 (pt) método para um polipeptídeo e/ou vírus de interesse em uma cultura de célula contínua,e, composição
BRPI0917050A2 (pt) célula bacteriana tolerante ao butanol, métodos para a produção de uma célula bacteriana tolerante ao butanol produtora de butanol e métodos para a produção de isobutanol
BR112012031847A2 (pt) cultura de produção para a produção fermentativa de butanol, método de produção de butanol, método para a produção de butanol, método para aumentar a tolerância de uma cultura de produção para a produção fermentativa de butanol e cultura de produção para produção fermentativa de butanol
BRPI0910304A2 (pt) recipiente para cultura de planta, método para cultura de planta e método de produção de muda de corte
BR112012007168A2 (pt) "célula de levedura, célula microbiana que produz isobutanol, célula hospedeira microbiana, método para conversão de acetolacto em diidróxi-isovalerato, método para a produção de isobutanol e plasmídeo"
EP2175029A4 (en) PROCESS FOR PRODUCING LACTIC ACID
BRPI0905928A2 (pt) "método de produção de ácido lático"
BRPI0811364A2 (pt) "separador de aço inoxidável para uma célula de combustível e método para manufaturar o separador de aço inoxidável para célula de combustível"
ZA201501179B (en) Culture medium composition, and method for culturing cell or tissue using said composition
BR112012006670A2 (pt) célula bacteriana gram-negativa recombinante, e, método para produzir uma proteína recombinante
ZA201201974B (en) Method for the preparation of 2,5-furandicarboxylic acid and for the prepartion of the dialkyl ester of 2,5-furandicarboxylic acid
BRPI0811492B8 (pt) método para produzir uma bebida láctea acidificada, bebida láctea acidificada, e, polipeptídeo isolado com atividade desamidase
WO2012051344A3 (en) Maintaining multiple defined physiological zones using model predictive control
BRPI1008634A2 (pt) "um meio de conexão, um método de fabricação do mesmo e uma conexão de material".
IL210487A0 (en) Method for controlling ph, osmolality and dissolved carbon dioxide levels in a mammalian cell culture process to enhance cell viability and biologic product yield
BR112012012492A2 (pt) métodos para aumentar atividade de diidróxi ácido desidratase para aperfeiçoar produção de combustíveis, produtos químicos e aminoácidos
ZA201003514B (en) Method for controlling the butanol concentration in a fermentation broth during butanol production
BRPI0907339A2 (pt) "método para produção de níquel e cobalto usando hidróxido metálico, óxido de metal e/ou carbonato de metal"
DK2112219T3 (da) Nye mælkesyrebakterier
EP2529431A4 (fr) Procede d'optimisation d'un materiau de cathode et materiau de cathode ayant des propriétés électrochimiques améliorées
BR112012003534A2 (pt) "sistema de produção de eletrólito e método para a produção de eletrólito sólido"
BR112013015058A2 (pt) micro-organismos e métodos para a produção de 1,4-ciclo-hexanodimetanol
BR112013021775A2 (pt) bactéria corineforme, e, método para produzir um l-aminoácido
EP2221373A4 (en) EXPRESSION CASSETTE FOR LACTASE DEHYDROGENASE, PROCESSED YEAST AND METHOD FOR PRODUCING LACTIC ACID
EP2604427A4 (en) LAMINATE AND LAMINATE MANUFACTURING METHOD

Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.