BRPI0913985A2 - processo de medição da taxa de fator vii ativado em uma amostra-teste e utilização de um plasma desprovido de fvii e de pelo menos outro fator escolhido entre o fviii, o fix e o fxi - Google Patents

processo de medição da taxa de fator vii ativado em uma amostra-teste e utilização de um plasma desprovido de fvii e de pelo menos outro fator escolhido entre o fviii, o fix e o fxi

Info

Publication number
BRPI0913985A2
BRPI0913985A2 BRPI0913985A BRPI0913985A BRPI0913985A2 BR PI0913985 A2 BRPI0913985 A2 BR PI0913985A2 BR PI0913985 A BRPI0913985 A BR PI0913985A BR PI0913985 A BRPI0913985 A BR PI0913985A BR PI0913985 A2 BRPI0913985 A2 BR PI0913985A2
Authority
BR
Brazil
Prior art keywords
fxi
fvii
fviii
fix
test sample
Prior art date
Application number
BRPI0913985A
Other languages
English (en)
Inventor
Claudine Mazurier
Dominique Grenier
Lysiane Hilbert
Original Assignee
Lfb Biotechnologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lfb Biotechnologies filed Critical Lfb Biotechnologies
Publication of BRPI0913985A2 publication Critical patent/BRPI0913985A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96447—Factor VII (3.4.21.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0913985A 2008-07-02 2009-06-29 processo de medição da taxa de fator vii ativado em uma amostra-teste e utilização de um plasma desprovido de fvii e de pelo menos outro fator escolhido entre o fviii, o fix e o fxi BRPI0913985A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0803743A FR2933496B1 (fr) 2008-07-02 2008-07-02 Procede de mesure du taux de facteur vii active dans un echantillon
PCT/IB2009/006099 WO2010001219A1 (fr) 2008-07-02 2009-06-29 Procédé de mesure du taux de facteur vii activé dans un échantillon

Publications (1)

Publication Number Publication Date
BRPI0913985A2 true BRPI0913985A2 (pt) 2015-10-20

Family

ID=40291014

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0913985A BRPI0913985A2 (pt) 2008-07-02 2009-06-29 processo de medição da taxa de fator vii ativado em uma amostra-teste e utilização de um plasma desprovido de fvii e de pelo menos outro fator escolhido entre o fviii, o fix e o fxi

Country Status (10)

Country Link
US (1) US20110097754A1 (pt)
EP (1) EP2307890A1 (pt)
JP (1) JP2011526691A (pt)
KR (1) KR20110027800A (pt)
CN (1) CN102084254A (pt)
AU (1) AU2009265315A1 (pt)
BR (1) BRPI0913985A2 (pt)
CA (1) CA2727165A1 (pt)
FR (1) FR2933496B1 (pt)
WO (1) WO2010001219A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103185710B (zh) * 2013-02-04 2015-01-07 中国医学科学院输血研究所 人静脉注射免疫球蛋白中活化凝血因子ⅺ检测方法
TWI701435B (zh) * 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定ｆｖｉｉｉ的反應性之方法
TWI700300B (zh) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第ｖｉｉｉ凝血因子（ｆｖｉｉｉ）機能替代活性的物質之抗體
CR20180554A (es) 2016-04-28 2019-01-10 Chugai Pharmaceutical Co Ltd Preparaciones que contienen anticuerpos
CN106093440A (zh) * 2016-06-06 2016-11-09 中国人民解放军总医院 一种用于检测人体血液凝集功能的诊断试剂及其制备方法与使用方法
CN110461358A (zh) 2017-03-31 2019-11-15 公立大学法人奈良县立医科大学 可用于预防和/或治疗凝血因子ⅸ异常、包含代替凝血因子ⅷ的功能的多特异性抗原结合分子的药物组合物
CN107796793B (zh) * 2017-09-28 2020-04-10 中国科学技术大学 FXa的检测试剂及检测方法
CN119161488A (zh) 2017-11-01 2024-12-20 中外制药株式会社 具有降低的生物活性的抗体变体和同种型
JP6883899B1 (ja) * 2020-12-07 2021-06-09 株式会社血栓トランスレーショナルリサーチラボ 血液凝固検査試薬、および血液凝固検査方法
JP7152084B1 (ja) * 2022-02-22 2022-10-12 株式会社血栓トランスレーショナルリサーチラボ 組織因子経路インヒビターの抗凝固活性の検査試薬、検査試薬セット、および検査方法
CN115327128A (zh) * 2022-07-01 2022-11-11 深圳市帝迈生物技术有限公司 Viii因子活性测定试剂盒及其制备方法
CN119959556B (zh) * 2025-04-10 2025-07-25 成都蓉生药业有限责任公司 一种测定动物样本中rFVIIa浓度的ELISA试剂盒及其检测方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000007I2 (de) * 1986-04-09 2010-12-30 Genzyme Corp Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern
US5472850A (en) * 1991-04-10 1995-12-05 Oklahoma Medical Research Foundation Quantitative clotting assay for activated factor VII
CA2080428C (en) * 1991-10-22 2004-01-27 Ray F. Ebert A method for preparing a thromboplastin reagent from cultured cells that is suitable for use in the prothrombin time test
US6194394B1 (en) * 1998-07-01 2001-02-27 Sigma-Aldrich Co. Coagulation controls for prothrombin time (PT) and activated partial thromboplastin time (APTT) assays
US7160540B2 (en) * 2000-06-30 2007-01-09 Regents Of The University Of Minnesota Methods for detecting activity of clottings factors
JP4584574B2 (ja) * 2001-07-03 2010-11-24 オゥクラホゥマ、メディカル、リサーチ、ファウンデイシャン 第ＶＩＩａ因子−アンチトロンビン複合体を測定するためのアッセイ
ATE368229T1 (de) * 2002-05-01 2007-08-15 Synapse Bv Diagnostischer test zur bestimmung der konzentration einer transienten proteolytischen aktivität in zusammengesetzten biologischen medien
US20080260858A1 (en) * 2005-02-16 2008-10-23 The Board Of Trustees Of The University Of Illnois Universal Procoagulant
EP1717588A1 (en) * 2005-04-29 2006-11-02 Synapse B.V. Measuring thrombin activity in whole blood
EP2360269A1 (en) * 2005-07-28 2011-08-24 American Diagnostica Inc. Lupus anticoagulant testing
FR2892724B1 (fr) * 2005-11-02 2008-01-04 Lab Francais Du Fractionnement Anticorps cytotoxiques diriges contre des anticorps inhibiteurs du facteur viii.
FR2894145B1 (fr) * 2005-12-07 2008-10-17 Lab Francais Du Fractionnement Utilisation de facteur h du complement a titre de medicament
FR2895262B1 (fr) * 2005-12-22 2009-07-17 Lab Francais Du Fractionnement Inhibition de la reponse immunitaire anti-fviii
FR2897868B1 (fr) * 2006-02-24 2012-08-31 Lab Francais Du Fractionnement Anticorps anti-idiotypiques neutralisant l'activite inhibitrice d'un anticorps inhibiteur dirige contre le domaine c1 du facteur viii.
FR2901707B1 (fr) * 2006-05-31 2017-09-29 Lab Francais Du Fractionnement Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis
FR2904558B1 (fr) * 2006-08-01 2008-10-17 Lab Francais Du Fractionnement "composition de facteur vii recombinant ou transgenique, presentant majoritairement des formes glycanniques biantennees, bisialylees et non fucosylees"
FR2910969B1 (fr) * 2006-12-29 2009-02-27 Lab Francais Du Fractionnement Procede de mesure de la concentration de facteur viia (fviia) dans un echantillon
EP1985631A1 (en) * 2007-04-20 2008-10-29 LFB Biotechnologies Demannosylated recombinant factor VIII for the treatment of patients with hemophiila A
FR2918375B1 (fr) * 2007-07-05 2009-10-16 Lab Francais Du Fractionnement Utilisation d'un support de chromatographie pour reduire la quantite d'adamts13 dans une solution derivee du plasma
FR2920429B1 (fr) * 2007-08-30 2012-10-05 Lfb Biotechnologies Procede de purification du facteur viii et du facteur von willebrand

Also Published As

Publication number Publication date
US20110097754A1 (en) 2011-04-28
KR20110027800A (ko) 2011-03-16
FR2933496A1 (fr) 2010-01-08
WO2010001219A1 (fr) 2010-01-07
JP2011526691A (ja) 2011-10-13
AU2009265315A1 (en) 2010-01-07
CN102084254A (zh) 2011-06-01
EP2307890A1 (fr) 2011-04-13
FR2933496B1 (fr) 2012-10-05
CA2727165A1 (en) 2010-01-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.