BRPI0914665A2 - derivados de pirimido[2,1-a]isoquinolin-4-ona substituída - Google Patents

derivados de pirimido[2,1-a]isoquinolin-4-ona substituída

Info

Publication number: BRPI0914665A2
Authority: BR; Brazil
Prior art keywords: isoquinolin; derivatives; substituted pyrimido; pyrimido; substituted
Prior art date: 2008-06-26

Application number

BRPI0914665A

Other languages

English (en)

Inventor

Alistair Lochead

Mourad Saady

Philippe Yaiche

Original Assignee

Mitsubishi Tanabe Pharma Corp

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-26

Filing date

2009-06-25

Publication date

2015-10-20

2009-06-25 Application filed by Mitsubishi Tanabe Pharma Corp, Sanofi Aventis filed Critical Mitsubishi Tanabe Pharma Corp

2015-10-20 Publication of BRPI0914665A2 publication Critical patent/BRPI0914665A2/pt

Links

YTWIBNSJMKAVML-UHFFFAOYSA-N pyrimido[2,1-a]isoquinolin-4-one Chemical class C1=CC=C2C=CN3C(=O)C=CN=C3C2=C1 YTWIBNSJMKAVML-UHFFFAOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Tropical Medicine & Parasitology (AREA)
Orthopedic Medicine & Surgery (AREA)
Endocrinology (AREA)
Obesity (AREA)
Oncology (AREA)
Plant Pathology (AREA)
Heart & Thoracic Surgery (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Agronomy & Crop Science (AREA)
Wood Science & Technology (AREA)
Dentistry (AREA)
Pest Control & Pesticides (AREA)
Zoology (AREA)
Environmental Sciences (AREA)

BRPI0914665A 2008-06-26 2009-06-25 derivados de pirimido[2,1-a]isoquinolin-4-ona substituída BRPI0914665A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08290618A EP2138495A1 (en)	2008-06-26	2008-06-26	Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
PCT/IB2009/006460 WO2009156859A1 (en)	2008-06-26	2009-06-25	Substituted pyrimido [2, 1-a] isoquinolin-4-one derivatives

Publications (1)

Publication Number	Publication Date
BRPI0914665A2 true BRPI0914665A2 (pt)	2015-10-20

Family

ID=39971001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0914665A BRPI0914665A2 (pt)	2008-06-26	2009-06-25	derivados de pirimido[2,1-a]isoquinolin-4-ona substituída

Country Status (16)

Country	Link
US (1)	US8211903B2 (pt)
EP (2)	EP2138495A1 (pt)
JP (1)	JP5501352B2 (pt)
KR (1)	KR20110027803A (pt)
CN (1)	CN102076683A (pt)
AR (1)	AR072228A1 (pt)
AU (1)	AU2009263845A1 (pt)
BR (1)	BRPI0914665A2 (pt)
CA (1)	CA2728693A1 (pt)
EA (1)	EA201170094A1 (pt)
IL (1)	IL210171A0 (pt)
MX (1)	MX2010013941A (pt)
NZ (1)	NZ590045A (pt)
TW (1)	TW201014854A (pt)
WO (1)	WO2009156859A1 (pt)
ZA (1)	ZA201009270B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2138493A1 (en) *	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidone derivatives
EP2138485A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	Substituted N-Oxide pyrazine derivatives
EP2138488A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
EP2138498A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	Substituted tricyclic derivatives against neurodegenerative diseases
EP2138494A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted alkyl pyrimidin-4-one derivatives
EP2138492A1 (en) *	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidin-4-one derivatives
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

Family Cites Families (21)

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Publication number	Priority date	Publication date	Assignee	Title
JPS5170780A (ja)	1974-12-17	1976-06-18	Nippon Shinyaku Co Ltd	Shinkinabenzoguanidoruino seiho
EG13192A (en)	1976-02-10	1982-12-31	Rhone Poulenc Ind	Nouveaux derives du dithiole-1,2 leur preparation et les compositions qui les contiennent
HU178496B (en)	1977-12-29	1982-05-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity
US4406897A (en)	1981-07-06	1983-09-27	William H. Rorer, Inc.	6-Aryl-4-hydrazinyl-s-triazin-2-ones
US4804663A (en)	1985-03-27	1989-02-14	Janssen Pharmaceutica N.V.	3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US5629322A (en)	1994-11-15	1997-05-13	Merck & Co., Inc.	Cyclic amidine analogs as inhibitors of nitric oxide synthase
WO1997016430A1 (en)	1995-11-01	1997-05-09	Merck & Co., Inc.	Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
IL123986A (en)	1997-04-24	2011-10-31	Organon Nv	Medicinal compounds
CN100415743C (zh) *	1999-03-31	2008-09-03	韦尔纳利斯有限公司	嘧啶并[6,1-a] 异喹啉-4-酮衍生物
EP1136484A1 (en)	2000-03-23	2001-09-26	Sanofi-Synthelabo	2-(Arylalkylamino)pyrimidone derivatives
WO2002087589A1 (en)	2001-04-26	2002-11-07	Daiichi Pharmaceutical Co., Ltd.	Medicine for inhibiting drug elimination pump
ES2250721T3 (es)	2001-09-21	2006-04-16	Sanofi-Aventis	Derivados de 2-pirimidinil-6,7,8,9-tetrahidropirimido(1,2-a)pirimidin-4-ona y 7-pirimidinil-2,3-dihidroimidazo(1,2-a)pirimidin-5(1h)ona sustituidos para enfermedades neurodegenerativas.
NZ538420A (en)	2002-08-16	2007-06-29	Kinacia Pty Ltd	Inhibition of phosphoinositide 3-kinase beta
EP1454909B1 (en) *	2003-03-07	2008-08-20	Sanofi Aventis	8'-pyridinyl-dihydrospiro- (cycloalkyl) -pyrimido (1,2-a) pyrimidin-6-one and 8'-pyrimidinyl-dihydrospiro (cycloalkyl) -pyrimido (1,2-a) pyrimidin-6-one derivatives and their use against neurodegenerative diseases
EP1460076A1 (en)	2003-03-21	2004-09-22	Sanofi-Synthelabo	Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives
EP1790649A1 (en) *	2005-11-21	2007-05-30	Sanofi-Aventis	Substituted bicyclic pyrimidone derivatives
EP2138488A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
EP2138494A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted alkyl pyrimidin-4-one derivatives
EP2138485A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	Substituted N-Oxide pyrazine derivatives
EP2138493A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidone derivatives
EP2138492A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidin-4-one derivatives

2008
- 2008-06-26 EP EP08290618A patent/EP2138495A1/en not_active Withdrawn
2009
- 2009-06-24 AR ARP090102316A patent/AR072228A1/es unknown
- 2009-06-24 TW TW098121232A patent/TW201014854A/zh unknown
- 2009-06-25 CA CA2728693A patent/CA2728693A1/en not_active Abandoned
- 2009-06-25 KR KR1020117001901A patent/KR20110027803A/ko not_active Withdrawn
- 2009-06-25 BR BRPI0914665A patent/BRPI0914665A2/pt not_active IP Right Cessation
- 2009-06-25 AU AU2009263845A patent/AU2009263845A1/en not_active Abandoned
- 2009-06-25 NZ NZ590045A patent/NZ590045A/en not_active IP Right Cessation
- 2009-06-25 EA EA201170094A patent/EA201170094A1/ru unknown
- 2009-06-25 JP JP2011515666A patent/JP5501352B2/ja not_active Expired - Fee Related
- 2009-06-25 MX MX2010013941A patent/MX2010013941A/es not_active Application Discontinuation
- 2009-06-25 CN CN200980124554XA patent/CN102076683A/zh active Pending
- 2009-06-25 WO PCT/IB2009/006460 patent/WO2009156859A1/en not_active Ceased
- 2009-06-25 EP EP09769670.2A patent/EP2321313B1/en active Active
2010
- 2010-12-15 US US12/968,950 patent/US8211903B2/en not_active Expired - Fee Related
- 2010-12-22 IL IL210171A patent/IL210171A0/en unknown
- 2010-12-23 ZA ZA2010/09270A patent/ZA201009270B/en unknown

Also Published As

Publication number	Publication date
IL210171A0 (en)	2011-03-31
JP5501352B2 (ja)	2014-05-21
EP2138495A1 (en)	2009-12-30
EP2321313A1 (en)	2011-05-18
TW201014854A (en)	2010-04-16
ZA201009270B (en)	2012-03-28
EP2321313B1 (en)	2015-09-02
MX2010013941A (es)	2011-06-24
CA2728693A1 (en)	2009-12-30
US8211903B2 (en)	2012-07-03
WO2009156859A1 (en)	2009-12-30
AR072228A1 (es)	2010-08-11
EA201170094A1 (ru)	2011-08-30
KR20110027803A (ko)	2011-03-16
AU2009263845A1 (en)	2009-12-30
CN102076683A (zh)	2011-05-25
JP2011525904A (ja)	2011-09-29
NZ590045A (en)	2011-11-25
US20110144138A1 (en)	2011-06-16

Legal Events

Date	Code	Title	Description
2015-12-08	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.
2016-04-05	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
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