BRPI0914787A2 - antibióticos trinem e inibidores de beta-lactamases - Google Patents

antibióticos trinem e inibidores de beta-lactamases

Info

Publication number
BRPI0914787A2
BRPI0914787A2 BRPI0914787A BRPI0914787A BRPI0914787A2 BR PI0914787 A2 BRPI0914787 A2 BR PI0914787A2 BR PI0914787 A BRPI0914787 A BR PI0914787A BR PI0914787 A BRPI0914787 A BR PI0914787A BR PI0914787 A2 BRPI0914787 A2 BR PI0914787A2
Authority
BR
Brazil
Prior art keywords
trinem
antibiotics
beta
lactamase inhibitors
lactamase
Prior art date
Application number
BRPI0914787A
Other languages
English (en)
Inventor
Andrej Prezelj
Barbara Mohar
Ivan Plantan
Michel Stephan
Uros Urleb
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Publication of BRPI0914787A2 publication Critical patent/BRPI0914787A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BRPI0914787A 2008-06-18 2009-06-18 antibióticos trinem e inibidores de beta-lactamases BRPI0914787A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08158454A EP2135871A1 (en) 2008-06-18 2008-06-18 New trinem antibiotics and inhibitors of beta-lactamases
PCT/EP2009/057558 WO2009153297A1 (en) 2008-06-18 2009-06-18 New trinem antibiotics and inhibitors of beta-lactamases

Publications (1)

Publication Number Publication Date
BRPI0914787A2 true BRPI0914787A2 (pt) 2015-10-20

Family

ID=39830233

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914787A BRPI0914787A2 (pt) 2008-06-18 2009-06-18 antibióticos trinem e inibidores de beta-lactamases

Country Status (10)

Country Link
US (1) US20110166118A1 (pt)
EP (2) EP2135871A1 (pt)
JP (1) JP2011524879A (pt)
CN (1) CN102066375A (pt)
AU (1) AU2009259342A1 (pt)
BR (1) BRPI0914787A2 (pt)
CA (1) CA2727362A1 (pt)
MX (1) MX2010014248A (pt)
RU (1) RU2011101493A (pt)
WO (1) WO2009153297A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017002903A1 (ja) * 2015-06-30 2017-01-05 塩野義製薬株式会社 スルフィニルまたはスルホニルを有する三環性化合物
RS63461B1 (sr) 2017-05-08 2022-08-31 Glaxosmithkline Ip Dev Ltd Sanfetrinem ili njegova so ili estar za upotrebu u lečenju mikobakterijske infekcije

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ435990A3 (cs) * 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
EP0464900A3 (en) * 1990-06-26 1992-07-22 Merck & Co. Inc. 2-biphenyl-carbapenems
IL99011A0 (en) * 1990-08-01 1992-07-15 Merck & Co Inc 2-(9-fluorenonyl)-carbapenems and pharmaceutical compositions containing them
ATE106887T1 (de) * 1990-08-21 1994-06-15 Glaxo Spa Ester der 10-(1-hydroxy-äthyl)-11-oxo-1- azatricyclo(7.2.0.0(3,8)>undec-2-ene-2- carbonsäure und deren derivate und verfahren zu ihrer herstellung.
EP0507313A1 (en) * 1991-04-05 1992-10-07 Takeda Chemical Industries, Ltd. Polycyclic carbapenem compounds, their production and use
SI9600371B (sl) * 1996-12-18 2005-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Etilidenski derivati tricikličnih karbapenemov

Also Published As

Publication number Publication date
AU2009259342A1 (en) 2009-12-23
MX2010014248A (es) 2011-03-21
JP2011524879A (ja) 2011-09-08
EP2307415A1 (en) 2011-04-13
WO2009153297A1 (en) 2009-12-23
CA2727362A1 (en) 2009-12-23
RU2011101493A (ru) 2012-07-27
CN102066375A (zh) 2011-05-18
EP2135871A1 (en) 2009-12-23
US20110166118A1 (en) 2011-07-07

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A, 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.