BRPI0914877A2 - método de purificação de eritropoietina - Google Patents
método de purificação de eritropoietinaInfo
- Publication number
- BRPI0914877A2 BRPI0914877A2 BRPI0914877A BRPI0914877A BRPI0914877A2 BR PI0914877 A2 BRPI0914877 A2 BR PI0914877A2 BR PI0914877 A BRPI0914877 A BR PI0914877A BR PI0914877 A BRPI0914877 A BR PI0914877A BR PI0914877 A2 BRPI0914877 A2 BR PI0914877A2
- Authority
- BR
- Brazil
- Prior art keywords
- purification method
- erythropoietin purification
- erythropoietin
- purification
- Prior art date
Links
- 102000003951 Erythropoietin Human genes 0.000 title 1
- 108090000394 Erythropoietin Proteins 0.000 title 1
- 229940105423 erythropoietin Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008002209A DE102008002209A1 (de) | 2008-06-04 | 2008-06-04 | Verfahren zur Aufreinigung von Erythropoietin |
| PCT/EP2009/056544 WO2009147060A1 (de) | 2008-06-04 | 2009-05-28 | Verfahren zur aufreinigung von erythropoietin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0914877A2 true BRPI0914877A2 (pt) | 2015-11-24 |
Family
ID=41056756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0914877A BRPI0914877A2 (pt) | 2008-06-04 | 2009-05-28 | método de purificação de eritropoietina |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20110152506A1 (pt) |
| EP (1) | EP2283036A1 (pt) |
| JP (1) | JP2011521993A (pt) |
| CN (1) | CN102056940A (pt) |
| BR (1) | BRPI0914877A2 (pt) |
| CA (1) | CA2727042A1 (pt) |
| DE (1) | DE102008002209A1 (pt) |
| IL (1) | IL209654A0 (pt) |
| WO (1) | WO2009147060A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2325194A1 (en) * | 2009-11-24 | 2011-05-25 | Glycotope GmbH | Process for the purification of glycoproteins |
| US10617975B2 (en) | 2014-12-15 | 2020-04-14 | Merck Patent Gmbh | Target molecule capture from crude solutions |
| CN108348604B (zh) * | 2015-09-08 | 2022-04-29 | 沃特世科技公司 | 用于分析抗体-药物缀合物的多维色谱方法 |
| KR101847169B1 (ko) * | 2015-10-07 | 2018-04-09 | 주식회사 녹십자 | 지속형 에리트로포이에틴 함유 조성물 |
| JP6906497B2 (ja) * | 2016-03-09 | 2021-07-21 | Jcrファーマ株式会社 | 変異型ヒトエリスロポエチンの製造方法 |
| WO2018011381A1 (en) | 2016-07-15 | 2018-01-18 | F. Hoffmann-La Roche Ag | Method for purifying pegylated erythropoietin |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| IL77081A (en) | 1984-12-04 | 1999-10-28 | Genetics Inst | Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin |
| IL79176A (en) * | 1985-06-20 | 1992-06-21 | Kirin Amgen Inc | Process for the recovery of erythropoietin from a fluid |
| US4954437A (en) | 1986-09-15 | 1990-09-04 | Integrated Genetics, Inc. | Cell encoding recombinant human erythropoietin |
| WO1991005867A1 (en) | 1989-10-13 | 1991-05-02 | Amgen Inc. | Erythropoietin isoforms |
| IL118201A (en) | 1995-05-11 | 2004-12-15 | Roche Diagnostics Gmbh | Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof |
| US6265542B1 (en) * | 1997-10-24 | 2001-07-24 | Genentech, Inc. | Purification of molecules |
| BR9917606A (pt) | 1998-11-06 | 2002-12-31 | Bio Sidus S A | Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento |
| RU2004119818A (ru) | 2001-11-28 | 2006-01-10 | Сандоз АГ (CH) | Хроматографическая очистка рекомбинантного человеческого эритропоэтина |
| AU2003265235A1 (en) * | 2002-04-26 | 2003-12-19 | Genetech, Inc. | Non-affinity purification of proteins |
| DK1428878T3 (da) | 2002-12-13 | 2008-12-08 | Bioceuticals Arzneimittel Ag | Fremgangsmåde til produktion og oprensning af erythropoietin |
| EP1548031A1 (en) * | 2003-12-22 | 2005-06-29 | Dubai Genetics FZ-LLC | Nature-identical erythropoietin |
| DE102004027816A1 (de) | 2004-06-08 | 2006-01-05 | Bioceuticals Arzneimittel Ag | Verfahren zur Reinigung von Erythropoietin |
| MX2007007590A (es) * | 2004-12-22 | 2007-12-10 | Ambrx Inc | Composiciones que contienen, metodos que involucran y usos de aminoacidos no naturales y polipeptidos. |
-
2008
- 2008-06-04 DE DE102008002209A patent/DE102008002209A1/de not_active Withdrawn
-
2009
- 2009-05-28 EP EP09757442A patent/EP2283036A1/de not_active Withdrawn
- 2009-05-28 BR BRPI0914877A patent/BRPI0914877A2/pt not_active Application Discontinuation
- 2009-05-28 JP JP2011512075A patent/JP2011521993A/ja active Pending
- 2009-05-28 CA CA2727042A patent/CA2727042A1/en not_active Abandoned
- 2009-05-28 WO PCT/EP2009/056544 patent/WO2009147060A1/de not_active Ceased
- 2009-05-28 US US12/996,203 patent/US20110152506A1/en not_active Abandoned
- 2009-05-28 CN CN2009801207641A patent/CN102056940A/zh active Pending
-
2010
- 2010-11-30 IL IL209654A patent/IL209654A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2283036A1 (de) | 2011-02-16 |
| CA2727042A1 (en) | 2009-12-10 |
| US20110152506A1 (en) | 2011-06-23 |
| DE102008002209A1 (de) | 2009-12-10 |
| CN102056940A (zh) | 2011-05-11 |
| IL209654A0 (en) | 2011-02-28 |
| JP2011521993A (ja) | 2011-07-28 |
| WO2009147060A1 (de) | 2009-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |