BRPI0914877A2 - método de purificação de eritropoietina - Google Patents

método de purificação de eritropoietina

Info

Publication number
BRPI0914877A2
BRPI0914877A2 BRPI0914877A BRPI0914877A BRPI0914877A2 BR PI0914877 A2 BRPI0914877 A2 BR PI0914877A2 BR PI0914877 A BRPI0914877 A BR PI0914877A BR PI0914877 A BRPI0914877 A BR PI0914877A BR PI0914877 A2 BRPI0914877 A2 BR PI0914877A2
Authority
BR
Brazil
Prior art keywords
purification method
erythropoietin purification
erythropoietin
purification
Prior art date
Application number
BRPI0914877A
Other languages
English (en)
Inventor
Christian Birr
Dagmar Schopohl-König
Dietmar Reichert
Franz-Rudolf Kunz
Lars Faber
Monika Singhofer-Wowra
Rudolf Hanko
Wilfried Eul
Wolfgang Wienand
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of BRPI0914877A2 publication Critical patent/BRPI0914877A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0914877A 2008-06-04 2009-05-28 método de purificação de eritropoietina BRPI0914877A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008002209A DE102008002209A1 (de) 2008-06-04 2008-06-04 Verfahren zur Aufreinigung von Erythropoietin
PCT/EP2009/056544 WO2009147060A1 (de) 2008-06-04 2009-05-28 Verfahren zur aufreinigung von erythropoietin

Publications (1)

Publication Number Publication Date
BRPI0914877A2 true BRPI0914877A2 (pt) 2015-11-24

Family

ID=41056756

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914877A BRPI0914877A2 (pt) 2008-06-04 2009-05-28 método de purificação de eritropoietina

Country Status (9)

Country Link
US (1) US20110152506A1 (pt)
EP (1) EP2283036A1 (pt)
JP (1) JP2011521993A (pt)
CN (1) CN102056940A (pt)
BR (1) BRPI0914877A2 (pt)
CA (1) CA2727042A1 (pt)
DE (1) DE102008002209A1 (pt)
IL (1) IL209654A0 (pt)
WO (1) WO2009147060A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2325194A1 (en) * 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
JP6845139B2 (ja) 2014-12-15 2021-03-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 粗製溶液からの標的分子捕捉
WO2017044530A1 (en) * 2015-09-08 2017-03-16 Waters Technologies Corporation Multidimensional chromatoggraphy method for analysis of antibody-drug conjugates
KR101847169B1 (ko) * 2015-10-07 2018-04-09 주식회사 녹십자 지속형 에리트로포이에틴 함유 조성물
JP6906497B2 (ja) * 2016-03-09 2021-07-21 Ｊｃｒファーマ株式会社 変異型ヒトエリスロポエチンの製造方法
KR102470282B1 (ko) 2016-07-15 2022-11-24 에프. 호프만-라 로슈 아게 Ｐｅｇ화 에리트로포이에틴을 정제하기 위한 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ210501A (en) 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence
IL77081A (en) 1984-12-04 1999-10-28 Genetics Inst Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin
IL79176A (en) * 1985-06-20 1992-06-21 Kirin Amgen Inc Process for the recovery of erythropoietin from a fluid
US4954437A (en) 1986-09-15 1990-09-04 Integrated Genetics, Inc. Cell encoding recombinant human erythropoietin
KR100221066B1 (ko) 1989-10-13 1999-10-01 스튜어트 엘.왓트 에리트로포이에틴 유사체와 그를 포함하는 제약학적 조성물
IL118201A (en) 1995-05-11 2004-12-15 Roche Diagnostics Gmbh Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof
US6265542B1 (en) * 1997-10-24 2001-07-24 Genentech, Inc. Purification of molecules
BR9917606A (pt) 1998-11-06 2002-12-31 Bio Sidus S A Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento
EP1453857B1 (en) 2001-11-28 2014-08-13 Sandoz AG Chromatographic purification of recombinant human erythropoietin
WO2003102132A2 (en) * 2002-04-26 2003-12-11 Genetech, Inc. Non-affinity purification of proteins
DE60228460D1 (de) 2002-12-13 2008-10-02 Bioceuticals Arzneimittel Ag Verfahren zur Herstellung und Reinigung von Erythropoietin
EP1548031A1 (en) * 2003-12-22 2005-06-29 Dubai Genetics FZ-LLC Nature-identical erythropoietin
DE102004027816A1 (de) 2004-06-08 2006-01-05 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von Erythropoietin
EP2399893B1 (en) * 2004-12-22 2018-08-15 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides

Also Published As

Publication number Publication date
IL209654A0 (en) 2011-02-28
CA2727042A1 (en) 2009-12-10
US20110152506A1 (en) 2011-06-23
WO2009147060A1 (de) 2009-12-10
JP2011521993A (ja) 2011-07-28
DE102008002209A1 (de) 2009-12-10
CN102056940A (zh) 2011-05-11
EP2283036A1 (de) 2011-02-16

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]