BRPI0923541A2 - purificação de imunoglobulina - Google Patents

purificação de imunoglobulina

Info

Publication number: BRPI0923541A2
Authority: BR; Brazil
Prior art keywords: immunoglobulin purification; immunoglobulin; purification
Prior art date: 2008-12-22

Application number

BRPI0923541A

Other languages

English (en)

Inventor

Andreas Schaubmar

Marc Pompiati

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-22

Filing date

2009-12-18

Publication date

2016-01-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40668760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0923541(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-12-18 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2016-01-26 Publication of BRPI0923541A2 publication Critical patent/BRPI0923541A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Mycology (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Engineering & Computer Science (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

BRPI0923541A 2008-12-22 2009-12-18 purificação de imunoglobulina BRPI0923541A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08022236		2008-12-22
PCT/EP2009/009157 WO2010072381A1 (en)	2008-12-22	2009-12-18	Immunoglobulin purification

Publications (1)

Publication Number	Publication Date
BRPI0923541A2 true BRPI0923541A2 (pt)	2016-01-26

Family

ID=40668760

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0923541A BRPI0923541A2 (pt)	2008-12-22	2009-12-18	purificação de imunoglobulina

Country Status (12)

Country	Link
US (3)	US9631008B2 (pt)
EP (1)	EP2379108B1 (pt)
JP (1)	JP2012513425A (pt)
KR (1)	KR20110086184A (pt)
CN (1)	CN102264392A (pt)
AU (1)	AU2009331897A1 (pt)
BR (1)	BRPI0923541A2 (pt)
CA (1)	CA2745707A1 (pt)
ES (1)	ES2488542T3 (pt)
IL (1)	IL212646A0 (pt)
MX (1)	MX2011006654A (pt)
WO (1)	WO2010072381A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2007294731B2 (en)	2006-09-13	2014-04-17	Abbvie Inc.	Cell culture improvements
US8911964B2 (en)	2006-09-13	2014-12-16	Abbvie Inc.	Fed-batch method of making human anti-TNF-alpha antibody
BRPI0920572A8 (pt)	2008-10-20	2015-10-27	Abbott Lab	Inativação viral durante a purificação dos anticorpos
NZ592095A (en)	2008-10-20	2013-01-25	Abbott Lab	Isolation and purification of il-12 and tnf-alpha antibodies using protein a affinity chromatography
JP2012513425A (ja)	2008-12-22	2012-06-14	エフ．ホフマン−ラロシュアーゲー	免疫グロブリンの精製
KR101619865B1 (ko)	2010-07-30	2016-05-11	이엠디 밀리포어 코포레이션	크로마토그래피 매질
WO2012030512A1 (en) *	2010-09-03	2012-03-08	Percivia Llc.	Flow-through protein purification process
IL212911A0 (en) *	2011-05-16	2011-07-31	Omrix Biopharmaceuticals Ltd	Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
EP2773439A4 (en) *	2011-10-31	2015-07-01	Merck Sharp & Dohme	CHROMATOGRAPHY METHOD FOR RESOLVING HETEROGENIC ANTIBODY AGGREGATES
EP3188816B1 (en)	2014-09-02	2021-06-09	EMD Millipore Corporation	Chromatography media comprising discrete porous bundles of nanofibrils
EP3230299A1 (en)	2014-12-08	2017-10-18	EMD Millipore Corporation	Mixed bed ion exchange adsorber
CN117242095A (zh) *	2021-04-23	2023-12-15	和铂医药(上海)有限责任公司	一种双特异性抗体的纯化方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4272521A (en)	1979-07-16	1981-06-09	Cutter Laboratories, Inc.	Purified immune serum globulin
US4604208A (en)	1983-12-29	1986-08-05	Chaokang Chu	Liquid filtration using an anionic microporous membrane
JPH0662436B2 (ja)	1986-05-19	1994-08-17	株式会社ミドリ十字	静注用免疫グロブリン製剤の製造方法
US5118796A (en)	1987-12-09	1992-06-02	Centocor, Incorporated	Efficient large-scale purification of immunoglobulins and derivatives
US4983722A (en)	1988-06-08	1991-01-08	Miles Inc.	Removal of protein A from antibody preparations
DE4118912C1 (pt)	1991-06-08	1992-07-02	Biotest Pharma Gmbh, 6072 Dreieich, De
BR9305557A (pt)	1992-06-26	1997-03-25	Aetsrn	Anticorpos monoclonais humanos anti Rhesus-D e composiçao farmacêutica que os contém
IT1271461B (it)	1993-12-01	1997-05-28	Menarini Ricerche Sud Spa	Anticorpo monoclonale bispecifico anti-cd3/anti-egfr,processo per la produzione e suo uso.
US5429746A (en)	1994-02-22	1995-07-04	Smith Kline Beecham Corporation	Antibody purification
CA2289665C (en)	1997-06-13	2005-08-09	Genentech, Inc.	Protein recovery by chromatography followed by filtration upon a charged layer
TW505655B (en) *	1997-10-14	2002-10-11	Tanox Inc	Enhanced aggregate removal from bulk-biologicals using ion exchange chromatography
EP1500661A1 (en)	1998-06-01	2005-01-26	Genetech, Inc.	Separation of protein monomers from aggregates by use of ion-exchange chromatography
EP1440304A2 (en)	2001-11-02	2004-07-28	Millipore Corporation	Membrane adsorber device
WO2003102132A2 (en)	2002-04-26	2003-12-11	Genetech, Inc.	Non-affinity purification of proteins
HUE033623T2 (en)	2002-09-11	2017-12-28	Genentech Inc	protein purification
GB0304576D0 (en)	2003-02-28	2003-04-02	Lonza Biologics Plc	Protein a chromatography
CA2516518A1 (en)	2003-02-28	2004-09-10	Lonza Biologics Plc.	Antibody purification by protein a and ion exchange chromatography
US20080058507A1 (en)	2004-02-11	2008-03-06	Hui Liu	Method For The Removal Of Aggregate Proteins From Recombinant Samples Using Ion Exchange Chromatography
CA2581208A1 (en)	2004-08-30	2006-03-09	Lonza Biologics Plc.	Affinity- plus ion exchange- chromatography for purifying antibodies
EP1869065B1 (en) *	2005-03-11	2020-05-06	Wyeth LLC	A method of weak partitioning chromatography
TW200720289A (en)	2005-04-01	2007-06-01	Hoffmann La Roche	Antibodies against CCR5 and uses thereof
ZA200710330B (en)	2005-06-17	2009-12-30	Wyeth Corp	Methods of purifying FC region containing proteins
WO2007075283A2 (en) *	2005-12-06	2007-07-05	Amgen Inc.	Polishing steps used in multi-step protein purification processes
CA2645739A1 (en)	2006-03-20	2007-09-27	Medarex, Inc.	Protein purification
CN102887955A (zh)	2006-04-05	2013-01-23	艾博特生物技术有限公司	抗体纯化
RU2474585C2 (ru)	2007-01-22	2013-02-10	Дженентек, Инк.	Осаждение и очистка белков полиэлектролитами
CN101679509A (zh) *	2007-06-01	2010-03-24	弗·哈夫曼-拉罗切有限公司	免疫球蛋白纯化
JP2012513425A (ja)	2008-12-22	2012-06-14	エフ．ホフマン−ラロシュアーゲー	免疫グロブリンの精製
WO2015188869A1 (en) *	2014-06-12	2015-12-17	Biosyn Arzneimittel Gmbh	Preparation methods for a novel generation of biological safe klh products used for cancer treatment, for the development of conjugated therapeutic vaccines and as challenging agents

2009
- 2009-12-18 JP JP2011542709A patent/JP2012513425A/ja active Pending
- 2009-12-18 EP EP09796320.1A patent/EP2379108B1/en not_active Revoked
- 2009-12-18 BR BRPI0923541A patent/BRPI0923541A2/pt not_active IP Right Cessation
- 2009-12-18 KR KR1020117014284A patent/KR20110086184A/ko not_active Ceased
- 2009-12-18 WO PCT/EP2009/009157 patent/WO2010072381A1/en not_active Ceased
- 2009-12-18 MX MX2011006654A patent/MX2011006654A/es not_active Application Discontinuation
- 2009-12-18 CA CA2745707A patent/CA2745707A1/en not_active Abandoned
- 2009-12-18 AU AU2009331897A patent/AU2009331897A1/en not_active Abandoned
- 2009-12-18 ES ES09796320.1T patent/ES2488542T3/es active Active
- 2009-12-18 US US13/141,306 patent/US9631008B2/en active Active
- 2009-12-18 CN CN2009801519516A patent/CN102264392A/zh active Pending
2011
- 2011-05-03 IL IL212646A patent/IL212646A0/en unknown
2017
- 2017-03-16 US US15/461,198 patent/US20180162930A1/en not_active Abandoned
2019
- 2019-08-12 US US16/538,604 patent/US20200207839A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP2379108A1 (en)	2011-10-26
AU2009331897A1 (en)	2010-07-01
CA2745707A1 (en)	2010-07-01
CN102264392A (zh)	2011-11-30
IL212646A0 (en)	2011-07-31
MX2011006654A (es)	2011-07-12
US9631008B2 (en)	2017-04-25
ES2488542T3 (es)	2014-08-27
US20180162930A1 (en)	2018-06-14
JP2012513425A (ja)	2012-06-14
WO2010072381A1 (en)	2010-07-01
US20110257370A1 (en)	2011-10-20
US20200207839A1 (en)	2020-07-02
KR20110086184A (ko)	2011-07-27
EP2379108B1 (en)	2014-06-25

Legal Events

Date	Code	Title	Description
2016-09-06	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 6A ANUIDADE.
2016-12-20	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2383 DE 06-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
BRPI0812288A2 (pt)	2014-11-25	Purificação de imunoglobulina.
BRPI0919237A2 (pt)	2015-12-15	purificação de policarbonatos
DK2274012T3 (da)	2014-08-18	Cytotoksisk immunoglobulin
BRPI0923541A2 (pt)	2016-01-26	purificação de imunoglobulina
BRPI0921327A2 (pt)	2015-08-25	Combinação de herbicida-protetor
BRPI0907457A2 (pt)	2015-07-14	Absorventes
BRPI0815042A2 (pt)	2015-02-10	Compostos de pirazol
BRPI0818380A2 (pt)	2014-10-07	Combinação de herbicida-protetor
BRPI0920835A2 (pt)	2015-12-22	escova de dentes
BRPI0813533A2 (pt)	2014-12-23	Purificação de conjugado
BRPI0919596A2 (pt)	2015-12-08	veículo
IL219021A (en)	2016-11-30	Rsv specific binding molecule
BRPI0815067A2 (pt)	2015-02-10	Compostos de biciclotactama substituída
BRPI0821868A2 (pt)	2015-07-28	Grânulo
BRPI0811014A2 (pt)	2015-01-27	Veículo
DE602008000562D1 (de)	2010-03-11	Fahrzeugrad
BRPI0809660A2 (pt)	2014-10-14	Carrinho de criança
BRPI0914210A2 (pt)	2015-11-03	conunto de filtro
BRPI0809659A2 (pt)	2014-10-14	Carrinho de criança
BRPI1005525A2 (pt)	2016-02-23	compostos de azaazuleno
BRPI0822884A2 (pt)	2015-06-30	Escova de dentes
BRPI0822906A2 (pt)	2015-06-30	Escova de dentes
DE602008001297D1 (de)	2010-07-01	Fahrzeugrad
ATE547159T1 (de)	2012-03-15	Fahrzeug
EP2259958A4 (en)	2012-02-08	LINKAGE