BRPI0916121A2 - "métodos para identificar câncer de próstata, método para identificar a presença de uma fusão gênica, kit e uso de uma composição" - Google Patents
"métodos para identificar câncer de próstata, método para identificar a presença de uma fusão gênica, kit e uso de uma composição"Info
- Publication number
- BRPI0916121A2 BRPI0916121A2 BRPI0916121A BRPI0916121A BRPI0916121A2 BR PI0916121 A2 BRPI0916121 A2 BR PI0916121A2 BR PI0916121 A BRPI0916121 A BR PI0916121A BR PI0916121 A BRPI0916121 A BR PI0916121A BR PI0916121 A2 BRPI0916121 A2 BR PI0916121A2
- Authority
- BR
- Brazil
- Prior art keywords
- identifying
- kit
- composition
- methods
- prostate cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/272,865 US9957569B2 (en) | 2005-09-12 | 2008-11-18 | Recurrent gene fusions in prostate cancer |
| PCT/US2009/064957 WO2010059702A2 (en) | 2008-11-18 | 2009-11-18 | Recurrent gene fusions in prostate cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0916121A2 true BRPI0916121A2 (pt) | 2015-11-03 |
| BRPI0916121A8 BRPI0916121A8 (pt) | 2018-06-19 |
Family
ID=41668351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0916121A BRPI0916121A8 (pt) | 2008-11-18 | 2009-11-18 | métodos para identificar câncer de próstata, composição, kit, método para identificar a presença de uma fusão gênica e uso de uma composição |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9957569B2 (pt) |
| EP (1) | EP2358899A2 (pt) |
| JP (3) | JP2012509068A (pt) |
| KR (1) | KR20110084995A (pt) |
| CN (1) | CN102812130A (pt) |
| AU (1) | AU2009316693B2 (pt) |
| BR (1) | BRPI0916121A8 (pt) |
| CA (1) | CA2744059A1 (pt) |
| IL (1) | IL212964A0 (pt) |
| WO (1) | WO2010059702A2 (pt) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9957569B2 (en) | 2005-09-12 | 2018-05-01 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| US7718369B2 (en) | 2005-09-12 | 2010-05-18 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| US8273539B2 (en) * | 2006-09-25 | 2012-09-25 | Mayo Foundation For Medical Education And Research | Extracellular and membrane-associated prostate cancer markers |
| US8338109B2 (en) | 2006-11-02 | 2012-12-25 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| WO2009009431A2 (en) | 2007-07-06 | 2009-01-15 | The Regents Of The University Of Michigan | Mipol1-etv1 gene rearrangements |
| WO2009020521A2 (en) | 2007-08-03 | 2009-02-12 | The Brigham And Women's Hospital, Inc. | Identification and treatment of estrogen responsive prostate tumors |
| EP2806054A1 (en) | 2008-05-28 | 2014-11-26 | Genomedx Biosciences Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| JP2012514475A (ja) * | 2009-01-09 | 2012-06-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 癌における再現性の遺伝子融合物 |
| CN102459648A (zh) | 2009-05-26 | 2012-05-16 | 奎斯特诊断投资公司 | 基因失调的检测方法 |
| JP5800817B2 (ja) | 2009-09-17 | 2015-10-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 前立腺癌における再発性遺伝子融合 |
| WO2011079191A1 (en) | 2009-12-23 | 2011-06-30 | Quest Diagnostics Investments Incorporated | Tmprss2 for the diagnosis of prostate disease |
| US9315802B2 (en) | 2009-12-30 | 2016-04-19 | Quest Diagnostics Investments Incorporated | RNA isolation from soluble urine fractions |
| CN103403181B (zh) * | 2010-11-19 | 2016-09-07 | 密执安大学评议会 | ncRNA及其用途 |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| US8945556B2 (en) | 2010-11-19 | 2015-02-03 | The Regents Of The University Of Michigan | RAF gene fusions |
| WO2012092490A1 (en) | 2010-12-30 | 2012-07-05 | Quest Diagnostics Investments Incorporated | Diagnosis of prostate cancer |
| WO2013090620A1 (en) | 2011-12-13 | 2013-06-20 | Genomedx Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| US9339812B2 (en) | 2012-02-13 | 2016-05-17 | Neumodx Molecular, Inc. | System and method for processing and detecting nucleic acids |
| US11648561B2 (en) | 2012-02-13 | 2023-05-16 | Neumodx Molecular, Inc. | System and method for processing and detecting nucleic acids |
| ES2945036T3 (es) | 2012-08-16 | 2023-06-28 | Veracyte Sd Inc | Pronóstico del cáncer de próstata mediante biomarcadores |
| ES2741749T3 (es) * | 2012-10-25 | 2020-02-12 | Neumodx Molecular Inc | Método y materiales para el aislamiento de materiales de ácido nucleico |
| CN103336914B (zh) * | 2013-05-31 | 2016-05-25 | 中国人民解放军国防科学技术大学 | 一种提取荟萃生物标志物的方法及装置 |
| US9994912B2 (en) | 2014-07-03 | 2018-06-12 | Abbott Molecular Inc. | Materials and methods for assessing progression of prostate cancer |
| IL311909B1 (en) | 2015-08-13 | 2025-11-01 | Takeda Pharmaceuticals Co | Method for assesing the level of drug targeting the contact system in a subject |
| AU2017315425B2 (en) | 2016-08-24 | 2023-11-09 | The Regents Of The University Of Michigan | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| EP3571322B9 (en) | 2017-01-20 | 2023-10-04 | VERACYTE SD, Inc. | Molecular subtyping, prognosis, and treatment of bladder cancer |
| CN106866824B (zh) * | 2017-03-06 | 2020-10-27 | 哈尔滨医科大学 | 一种抗ddx5的全人源单克隆抗体及其制备方法和应用 |
| CA3055925A1 (en) | 2017-03-09 | 2018-09-13 | Decipher Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| EP3600371A4 (en) | 2017-03-21 | 2021-06-09 | The Regents of The University of Michigan | AGAINST ERG THERAPY |
| US11078542B2 (en) | 2017-05-12 | 2021-08-03 | Decipher Biosciences, Inc. | Genetic signatures to predict prostate cancer metastasis and identify tumor aggressiveness |
| US10964410B2 (en) * | 2017-05-25 | 2021-03-30 | Koninklijke Philips N.V. | System and method for detecting gene fusion |
| US12497660B2 (en) | 2017-08-04 | 2025-12-16 | Veracyte SD, Inc. | Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy |
| US10769307B2 (en) | 2018-05-30 | 2020-09-08 | Bank Of America Corporation | Processing system using natural language processing for performing dataset filtering and sanitization |
| CN113528660A (zh) * | 2020-09-18 | 2021-10-22 | 深圳汇芯生物医疗科技有限公司 | 前列腺癌的风险评估装置 |
| CN112522404B (zh) * | 2020-12-10 | 2023-06-09 | 珠海中科先进技术研究院有限公司 | 一种用于检测前列腺癌的多重荧光pcr试剂盒 |
Family Cites Families (102)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4109496A (en) | 1977-12-20 | 1978-08-29 | Norris Industries | Trapped key mechanism |
| US4323546A (en) | 1978-05-22 | 1982-04-06 | Nuc Med Inc. | Method and composition for cancer detection in humans |
| GB2043675B (en) * | 1979-03-08 | 1983-02-23 | British Gas Corp | Gas oil purification |
| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| EP0232967B1 (en) | 1986-01-10 | 1993-04-28 | Amoco Corporation | Competitive homogeneous assay |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5080891A (en) | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| US5283174A (en) | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US4968103A (en) | 1988-07-22 | 1990-11-06 | Photofinish Cosmetics Inc. | Method of making a brush |
| US5225326A (en) | 1988-08-31 | 1993-07-06 | Research Development Foundation | One step in situ hybridization assay |
| EP0731175A3 (en) | 1989-07-11 | 2004-05-26 | Gen-Probe Incorporated | Oligonucleotide probes for HIV nucleic acid |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| US5614396A (en) | 1990-06-14 | 1997-03-25 | Baylor College Of Medicine | Methods for the genetic modification of endogenous genes in animal cells by homologous recombination |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
| US5545524A (en) | 1991-12-04 | 1996-08-13 | The Regents Of The University Of Michigan | Compositions and methods for chromosome region-specific probes |
| EP0552108B1 (en) | 1992-01-17 | 1999-11-10 | Lakowicz, Joseph R. | Energy transfer phase-modulation fluoro-immunoassay |
| DE69333969T2 (de) | 1992-10-30 | 2006-09-14 | The General Hospital Corp., Boston | Wechselwirkendes Fallensystem zur Isolierung von Proteinen |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| JP3448090B2 (ja) | 1994-02-16 | 2003-09-16 | 浜松ホトニクス株式会社 | エネルギー移動検出法およびその装置 |
| US20050214309A1 (en) | 1994-03-18 | 2005-09-29 | Hinrichs Steven H | Methods and compositions for modulating transcription factor activity |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| JP3189000B2 (ja) | 1994-12-01 | 2001-07-16 | 東ソー株式会社 | 特定核酸配列の検出方法 |
| US5856125A (en) | 1995-06-05 | 1999-01-05 | The United States Of America As Represented By The Department Of Health And Human Services | ETS2 repressor factor (ERF) genetic locus and its products |
| US5710029A (en) | 1995-06-07 | 1998-01-20 | Gen-Probe Incorporated | Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product |
| US5854206A (en) | 1995-08-25 | 1998-12-29 | Corixa Corporation | Compounds and methods for treatment and diagnosis of prostate cancer |
| US6121489A (en) | 1996-03-05 | 2000-09-19 | Trega Biosciences, Inc. | Selectively N-alkylated peptidomimetic combinatorial libraries and compounds therein |
| BR9708082A (pt) | 1996-03-15 | 1999-07-27 | Corixa Corp | Compostos e métodos para a imunoterapia e imunodiagnose de câncer de próstata |
| AU713667B2 (en) | 1996-04-12 | 1999-12-09 | Phri Properties, Inc. | Detection probes, kits and assays |
| AU4566997A (en) | 1996-10-07 | 1998-05-05 | Meat And Livestock Commission | Assay for duroc muscle fibre type |
| US7125969B1 (en) | 1996-11-27 | 2006-10-24 | The Regents Of The University Of California | ETS-related gene overexpressed in human breast and epithelial cancers |
| US6943236B2 (en) | 1997-02-25 | 2005-09-13 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US6395278B1 (en) | 1997-02-25 | 2002-05-28 | Corixa Corporation | Prostate specific fusion protein compositions |
| US20030185830A1 (en) | 1997-02-25 | 2003-10-02 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| CN1195851C (zh) | 1997-02-25 | 2005-04-06 | 科里克萨有限公司 | 用于前列腺癌免疫疗法的化合物及其用途 |
| US6043033A (en) | 1997-02-27 | 2000-03-28 | Incyte Pharmaceuticals, Inc. | Human prostate-associated protease |
| US20020119531A1 (en) | 1997-02-27 | 2002-08-29 | Olga Bandman | Prostate-associated protease antibody |
| US20030103981A1 (en) | 1997-02-27 | 2003-06-05 | Incyte Genomics, Inc. | Methods of use of a prostate-associated protease in the diagnosis and treatment of prostate cancer |
| WO1998039636A1 (en) | 1997-03-07 | 1998-09-11 | Clare Chemical Research Llc | Fluorometric detection using visible light |
| US6080912A (en) | 1997-03-20 | 2000-06-27 | Wisconsin Alumni Research Foundation | Methods for creating transgenic animals |
| JP3981416B2 (ja) | 1997-04-10 | 2007-09-26 | ユニバーシティ メディカル センター ナイメーヘン | Pca3タンパク質、pca3遺伝子、及びこれらの用途 |
| US6187799B1 (en) | 1997-05-23 | 2001-02-13 | Onyx Pharmaceuticals | Inhibition of raf kinase activity using aryl ureas |
| WO1999062942A2 (en) | 1998-06-01 | 1999-12-09 | Urogenesys, Inc. | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
| US7037667B1 (en) | 1998-06-01 | 2006-05-02 | Agensys, Inc. | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
| WO1999065929A1 (en) | 1998-06-16 | 1999-12-23 | The Regents Of The University Of California | Exons 4 and 7 encode separate transactivating and chromatin localizing domains in esx |
| AU4839999A (en) | 1998-06-29 | 2000-01-17 | Myriad Genetics, Inc. | Tmprss2 is a tumor suppressor |
| AU762728B2 (en) | 1998-07-02 | 2003-07-03 | Gen-Probe Incorporated | Molecular torches |
| KR20010083111A (ko) | 1998-07-14 | 2001-08-31 | 길리스 스티브 | 전립선암의 치료 및 진단을 위한 조성물 및 방법 |
| US7737255B1 (en) | 1998-09-02 | 2010-06-15 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating various cancers |
| US6872811B1 (en) | 1998-09-30 | 2005-03-29 | Millennium Pharmaceuticals, Inc. | HRPCa9 and HRPCa10 nucleic acids and polypeptides |
| EP1117836A2 (en) | 1998-09-30 | 2001-07-25 | Millennium Pharmaceuticals, Inc. | Expressionanalysis of specific nucleic acids and polypeptides useful in the diagnosis and treatment of prostate cancer |
| US6573043B1 (en) | 1998-10-07 | 2003-06-03 | Genentech, Inc. | Tissue analysis and kits therefor |
| US6902892B1 (en) | 1998-10-19 | 2005-06-07 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| JP2002527758A (ja) | 1998-10-19 | 2002-08-27 | ダイアデクスアス・インコーポレーテッド | 前立腺癌を診断、監視、病期分類、イメージング及び治療する方法 |
| US6828429B1 (en) | 1999-03-26 | 2004-12-07 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Prostate-specific gene, PCGEM1, and the methods of using PCGEM1 to detect, treat, and prevent prostate cancer |
| US6303305B1 (en) | 1999-03-30 | 2001-10-16 | Roche Diagnostics, Gmbh | Method for quantification of an analyte |
| WO2000065067A2 (en) | 1999-04-23 | 2000-11-02 | University Of Washington | Prostate-specific polynucleotides, polypeptides and their methods of use |
| EP1179093A1 (en) | 1999-05-14 | 2002-02-13 | Chiron Corporation | Expression of ets-domain proteins in cancer |
| EP1055734B1 (en) | 1999-05-24 | 2004-10-13 | Tosoh Corporation | Method for assaying ribonucleic acid |
| AU2001236519A1 (en) | 2000-01-24 | 2001-07-31 | Millennium Pharmaceuitcals, Inc. | Identification, assessment, prevention, and therapy of prostate cancer |
| DE10004102A1 (de) | 2000-01-31 | 2002-06-20 | Metagen Pharmaceuticals Gmbh | Nachweis von differenzieller Genexpression |
| WO2001060860A2 (en) | 2000-02-17 | 2001-08-23 | Millennium Predictive Medicine, Inc. | Genes differentially expressed in human prostate cancer and their use |
| WO2001088124A2 (en) | 2000-05-16 | 2001-11-22 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for the inhibition of erg |
| JP2004504068A (ja) | 2000-07-27 | 2004-02-12 | ザ オーストラリアン ナショナル ユニバーシティー | コンビナトリアル・プローブ及びそのための用途 |
| EP1318992B1 (en) | 2000-09-21 | 2005-07-27 | Smithkline Beecham Plc | Imidazole derivatives as raf kinase inhibitors |
| US7892730B2 (en) | 2000-12-22 | 2011-02-22 | Sagres Discovery, Inc. | Compositions and methods for cancer |
| US6897024B2 (en) | 2001-05-31 | 2005-05-24 | Stichting Katholieke Universiteit More Particularly The University Medical Centre Nijmegen | Nucleic acid molecules comprising the promoter for PCA3, and uses thereof |
| US20040009481A1 (en) | 2001-06-11 | 2004-01-15 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of human prostate cancer |
| WO2003009814A2 (en) | 2001-07-25 | 2003-02-06 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer |
| US6537811B1 (en) | 2001-08-01 | 2003-03-25 | Isis Pharmaceuticals, Inc. | Antisense inhibition of SAP-1 expression |
| US7229774B2 (en) | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
| US7507528B2 (en) | 2001-09-06 | 2009-03-24 | Adnagen Ag | Method and diagnosis kit for selecting and or qualitative and/or quantitative detection of cells |
| US6949342B2 (en) | 2001-12-21 | 2005-09-27 | Whitehead Institute For Biomedical Research | Prostate cancer diagnosis and outcome prediction by expression analysis |
| WO2004023973A2 (en) | 2002-09-12 | 2004-03-25 | Incyte Corporation | Molecules for diagnostics and therapeutics |
| US7217807B2 (en) | 2002-11-26 | 2007-05-15 | Rosetta Genomics Ltd | Bioinformatically detectable group of novel HIV regulatory genes and uses thereof |
| WO2004070056A2 (en) | 2003-02-07 | 2004-08-19 | Diagnocure Inc. | Method to detect prostate cancer in a sample |
| CA2516128A1 (en) | 2003-02-14 | 2004-09-02 | Sagres Discovery, Inc. | Therapeutic targets in cancer |
| WO2004092397A2 (en) | 2003-04-15 | 2004-10-28 | Novartis Ag | Tmprss2 regulatory sequences and uses thereof |
| JP2006525027A (ja) | 2003-05-01 | 2006-11-09 | ジェン−プロウブ インコーポレイテッド | 分子スイッチを含むオリゴヌクレオチド |
| WO2004097358A2 (en) | 2003-05-02 | 2004-11-11 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human transmembrane serine protease 2 (tmprss2) |
| EP2003196A3 (en) | 2003-06-09 | 2009-01-07 | The Regents of the University of Michigan | Compositions and methods for treating and diagnosing cancer |
| US7834163B2 (en) | 2003-06-26 | 2010-11-16 | Exonhit Therapeutics S.A. | Prostate specific genes and the use thereof as targets for prostate cancer therapy |
| CA2432365A1 (en) | 2003-06-30 | 2004-12-30 | Jack A. Schalken | Specific method of prostate cancer detection based on pca3, and kits therefore |
| WO2005007090A2 (en) | 2003-07-03 | 2005-01-27 | President And Fellows Of Harvard College | Inhibitors of the map kinase pathway |
| WO2005007830A2 (en) | 2003-07-14 | 2005-01-27 | Mayo Foundation For Medical Education And Research | Methods and compositions for diagnosis, staging and prognosis of prostate cancer |
| JP4574619B2 (ja) | 2003-09-05 | 2010-11-04 | トーマス・ジェファーソン・ユニバーシティ | 肝細胞癌の検査及び監視 |
| AU2005245815B2 (en) * | 2004-05-07 | 2011-06-09 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Methods of diagnosing or treating prostate cancer using the erg gene, alone or in combination with other over or under expressed genes in prostate cancer |
| CA2576624A1 (en) | 2004-08-13 | 2006-03-16 | Millennium Pharmaceuticals, Inc. | Genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer |
| US7374885B2 (en) | 2004-08-27 | 2008-05-20 | Gen-Probe Incorporated | Single-primer nucleic acid amplification methods |
| US20060275794A1 (en) | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
| US7638278B2 (en) | 2005-05-13 | 2009-12-29 | The Board Of Trustees Of The Leland Stanford Junior University | Markers of DNA copy number alteration for improved prognostication in prostate cancer |
| US9957569B2 (en) | 2005-09-12 | 2018-05-01 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| US7718369B2 (en) | 2005-09-12 | 2010-05-18 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| EP2074225B1 (en) | 2006-10-10 | 2014-12-03 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Prostate cancer-specific alterations in erg gene expression and detection and treatment methods based on those alterations |
| EP2167689B1 (en) | 2007-07-06 | 2012-10-31 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| WO2009044899A1 (ja) | 2007-10-03 | 2009-04-09 | Kyowa Hakko Kirin Co., Ltd. | 細胞の増殖を制御する核酸 |
| WO2010096660A2 (en) | 2009-02-19 | 2010-08-26 | Cornell University | Compositions and methods for diagnosing prostate cancer based on detection of slc45a3-elk4 fusion transcript |
| JP5800817B2 (ja) | 2009-09-17 | 2015-10-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 前立腺癌における再発性遺伝子融合 |
-
2008
- 2008-11-18 US US12/272,865 patent/US9957569B2/en active Active
-
2009
- 2009-11-18 KR KR1020117013985A patent/KR20110084995A/ko not_active Ceased
- 2009-11-18 BR BRPI0916121A patent/BRPI0916121A8/pt not_active Application Discontinuation
- 2009-11-18 WO PCT/US2009/064957 patent/WO2010059702A2/en not_active Ceased
- 2009-11-18 CA CA2744059A patent/CA2744059A1/en not_active Abandoned
- 2009-11-18 CN CN2009801548345A patent/CN102812130A/zh active Pending
- 2009-11-18 AU AU2009316693A patent/AU2009316693B2/en active Active
- 2009-11-18 EP EP09760397A patent/EP2358899A2/en not_active Withdrawn
- 2009-11-18 JP JP2011536616A patent/JP2012509068A/ja not_active Withdrawn
-
2011
- 2011-05-17 IL IL212964A patent/IL212964A0/en unknown
-
2015
- 2015-07-07 JP JP2015135837A patent/JP2015177809A/ja active Pending
-
2017
- 2017-11-02 JP JP2017212472A patent/JP2018019720A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018019720A (ja) | 2018-02-08 |
| WO2010059702A2 (en) | 2010-05-27 |
| US9957569B2 (en) | 2018-05-01 |
| JP2015177809A (ja) | 2015-10-08 |
| AU2009316693B2 (en) | 2012-08-23 |
| BRPI0916121A8 (pt) | 2018-06-19 |
| JP2012509068A (ja) | 2012-04-19 |
| WO2010059702A3 (en) | 2010-07-29 |
| CA2744059A1 (en) | 2010-05-27 |
| IL212964A0 (en) | 2011-07-31 |
| AU2009316693A1 (en) | 2010-05-27 |
| US20090239221A1 (en) | 2009-09-24 |
| CN102812130A (zh) | 2012-12-05 |
| KR20110084995A (ko) | 2011-07-26 |
| EP2358899A2 (en) | 2011-08-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BRPI0916121A2 (pt) | "métodos para identificar câncer de próstata, método para identificar a presença de uma fusão gênica, kit e uso de uma composição" | |
| BRPI0819338A2 (pt) | Preparações, métodos e kits úteis para o tratamento de tosse | |
| ZA201001789B (en) | Composition and methods for use for antibodies against sclerostin | |
| BRPI0811635A2 (pt) | Compostos de arilazol-2-il cianoetilamino, métodos para fazê-los e métodos para o uso dos mesmos | |
| BRPI0807132A2 (pt) | enzimas para o tratamento de lignocelulósicos, ácidos nucléicos que codificam as mesmas, e metodos e uso das mesmas | |
| BRPI0908854A2 (pt) | composições e métodos para o tratamento de tumor de origem hematopoética | |
| BRPI0716872A2 (pt) | Fosfolipases, ácidos nucléicos codificando-as e métodos para fabricação e uso delas | |
| EP2237311A4 (en) | POLISHING COMPOSITION AND POLISHING METHOD THEREFOR | |
| GB0820190D0 (en) | Tissue excision tool, kits and methods of using the same | |
| BRPI0822104A2 (pt) | Composições antimicrobianas e métodos para o uso das mesmas | |
| ZA200905886B (en) | Methods and kits for administering probiotics | |
| PL2371385T3 (pl) | Zastosowanie kompozycji immunogennej do zmniejszania objawów klinicznych u świń | |
| IL197668A0 (en) | Rna antagonist compounds for the modulation of pcsk9 | |
| BRPI0815138A2 (pt) | Métodos e organismos para a produção acoplada a crescimento de 1,4-butanodiol | |
| PT2278845E (pt) | Métodos e aparelhos para fornecimento de informação de programação | |
| CL2008001682A1 (es) | Metodos para el mejoramiento de plantas mediante el uso de informacion directa de secuencias de acidos nucleicos. | |
| BRPI0814330A2 (pt) | métodos e kits cirúrgicos | |
| BRPI0807220B1 (pt) | composição, e, métodos para aumentar a força de compressão de uma composição e para aumentar a retenção de fragrância de uma composição | |
| BRPI0909885A2 (pt) | composição decorativa e método para sua utilização | |
| PL2223121T3 (pl) | Sposób różnicowania NZJ i ZJD oraz dalsze rozróżnienie odmian NZJ | |
| BRPI0905990A2 (pt) | "método cosmético, combinação, composição e kits" | |
| BRPI0818323A2 (pt) | composição farmacêutica, uso de uma composição farmacêutica, e, método para tratar câncer. | |
| BRPI0811092A2 (pt) | Método de determinação do grau de um tumor, e, uso de 1 3c-piruvato hiperpolarizado | |
| NL1034834A1 (nl) | Flavonoïde-rijke weefsels van Neomarica gracilis en werkwijzen om deze te kweken. | |
| BRPI0718035A2 (pt) | Método e disposição para fabricação de metanol |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
|
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |