BRPI0916904A2 - polipeptídeos, moléculares de fusão ecd fgfr4, composições farmacêuticas, polinucleotídio e métodos de tratamento de desordem angiogênica, câncer em paciente e degeneração macular em paciente e respectivos usos - Google Patents

polipeptídeos, moléculares de fusão ecd fgfr4, composições farmacêuticas, polinucleotídio e métodos de tratamento de desordem angiogênica, câncer em paciente e degeneração macular em paciente e respectivos usos

Info

Publication number
BRPI0916904A2
BRPI0916904A2 BRPI0916904A BRPI0916904A BRPI0916904A2 BR PI0916904 A2 BRPI0916904 A2 BR PI0916904A2 BR PI0916904 A BRPI0916904 A BR PI0916904A BR PI0916904 A BRPI0916904 A BR PI0916904A BR PI0916904 A2 BRPI0916904 A2 BR PI0916904A2
Authority
BR
Brazil
Prior art keywords
patient
ecd
polynucleotide
polypeptides
methods
Prior art date
Application number
BRPI0916904A
Other languages
English (en)
Inventor
Ali Sadra
Deborah H Charych
Shannon Marshall
Original Assignee
Fiveprime Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fiveprime Therapeutics Inc filed Critical Fiveprime Therapeutics Inc
Publication of BRPI0916904A2 publication Critical patent/BRPI0916904A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0916904A 2008-08-04 2009-08-04 polipeptídeos, moléculares de fusão ecd fgfr4, composições farmacêuticas, polinucleotídio e métodos de tratamento de desordem angiogênica, câncer em paciente e degeneração macular em paciente e respectivos usos BRPI0916904A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8612108P 2008-08-04 2008-08-04
PCT/US2009/052704 WO2010017198A2 (en) 2008-08-04 2009-08-04 Fgfr extracellular domain acidic region muteins

Publications (1)

Publication Number Publication Date
BRPI0916904A2 true BRPI0916904A2 (pt) 2016-10-11

Family

ID=41110955

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0916904A BRPI0916904A2 (pt) 2008-08-04 2009-08-04 polipeptídeos, moléculares de fusão ecd fgfr4, composições farmacêuticas, polinucleotídio e métodos de tratamento de desordem angiogênica, câncer em paciente e degeneração macular em paciente e respectivos usos

Country Status (10)

Country Link
US (2) US8338569B2 (pt)
EP (1) EP2318529B1 (pt)
JP (1) JP5787757B2 (pt)
CN (1) CN102171343B (pt)
AU (1) AU2009279806B2 (pt)
BR (1) BRPI0916904A2 (pt)
CA (1) CA2732449A1 (pt)
IL (1) IL210914A (pt)
RU (1) RU2509774C2 (pt)
WO (1) WO2010017198A2 (pt)

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PT3242888T (pt) * 2015-01-07 2020-12-28 Pfizer Armadilhas de fgfr3 solúveis para o tratamento de distúrbios do crescimento ósseo
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Also Published As

Publication number Publication date
IL210914A0 (en) 2011-04-28
WO2010017198A2 (en) 2010-02-11
RU2509774C2 (ru) 2014-03-20
US20130004492A1 (en) 2013-01-03
CN102171343A (zh) 2011-08-31
JP2011529705A (ja) 2011-12-15
EP2318529A2 (en) 2011-05-11
AU2009279806A1 (en) 2010-02-11
US9175065B2 (en) 2015-11-03
AU2009279806B2 (en) 2015-04-30
WO2010017198A3 (en) 2010-04-29
CA2732449A1 (en) 2010-02-11
EP2318529B1 (en) 2017-10-18
IL210914A (en) 2016-09-29
RU2011103972A (ru) 2012-09-10
US8338569B2 (en) 2012-12-25
US20100087627A1 (en) 2010-04-08
JP5787757B2 (ja) 2015-09-30
CN102171343B (zh) 2017-07-14

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