BRPI0813311A2 - Composto, métodos para modulara a atividade de uma proteína quinase e para tratar câncer em um indivíduo, e, composição farmacêutica. - Google Patents

Composto, métodos para modulara a atividade de uma proteína quinase e para tratar câncer em um indivíduo, e, composição farmacêutica.

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Publication number
BRPI0813311A2
BRPI0813311A2 BRPI0813311-5A2A BRPI0813311A BRPI0813311A2 BR PI0813311 A2 BRPI0813311 A2 BR PI0813311A2 BR PI0813311 A BRPI0813311 A BR PI0813311A BR PI0813311 A2 BRPI0813311 A2 BR PI0813311A2
Authority
BR
Brazil
Prior art keywords
modulating
activity
individual
compound
methods
Prior art date
Application number
BRPI0813311-5A2A
Other languages
English (en)
Inventor
Jeffrey M Blaney
Andreas Gosberg
Stefan N Gradl
Gavin Hirst
Stephanie A Hopkins
Paul A Sprengeler
Ruo W Steensma
Johnny N Uy
Original Assignee
Sgx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sgx Pharmaceuticals Inc filed Critical Sgx Pharmaceuticals Inc
Publication of BRPI0813311A2 publication Critical patent/BRPI0813311A2/pt

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Diabetes (AREA)
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  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
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  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Vascular Medicine (AREA)
BRPI0813311-5A2A 2007-05-29 2008-05-29 Composto, métodos para modulara a atividade de uma proteína quinase e para tratar câncer em um indivíduo, e, composição farmacêutica. BRPI0813311A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94058907P 2007-05-29 2007-05-29
PCT/US2008/065150 WO2008150914A1 (en) 2007-05-29 2008-05-29 Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators

Publications (1)

Publication Number Publication Date
BRPI0813311A2 true BRPI0813311A2 (pt) 2014-12-23

Family

ID=40094108

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813311-5A2A BRPI0813311A2 (pt) 2007-05-29 2008-05-29 Composto, métodos para modulara a atividade de uma proteína quinase e para tratar câncer em um indivíduo, e, composição farmacêutica.

Country Status (16)

Country Link
US (1) US8158647B2 (pt)
EP (1) EP2056822A4 (pt)
JP (1) JP2010529035A (pt)
KR (1) KR20100041711A (pt)
CN (1) CN101778629A (pt)
AR (1) AR066904A1 (pt)
AU (1) AU2008260120A1 (pt)
BR (1) BRPI0813311A2 (pt)
CA (1) CA2689161A1 (pt)
CL (1) CL2008001540A1 (pt)
EA (1) EA200901538A1 (pt)
MX (1) MX2009013052A (pt)
PE (1) PE20090388A1 (pt)
TW (1) TW200908968A (pt)
UY (1) UY31113A1 (pt)
WO (1) WO2008150914A1 (pt)

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