BRPI0917290A8 - Composição imunológica - Google Patents
Composição imunológicaInfo
- Publication number
- BRPI0917290A8 BRPI0917290A8 BRPI0917290A BRPI0917290A BRPI0917290A8 BR PI0917290 A8 BRPI0917290 A8 BR PI0917290A8 BR PI0917290 A BRPI0917290 A BR PI0917290A BR PI0917290 A BRPI0917290 A BR PI0917290A BR PI0917290 A8 BRPI0917290 A8 BR PI0917290A8
- Authority
- BR
- Brazil
- Prior art keywords
- antigen
- immunological
- compositions
- virus
- immune response
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 8
- 230000001900 immune effect Effects 0.000 title abstract 7
- 239000000427 antigen Substances 0.000 abstract 5
- 102000036639 antigens Human genes 0.000 abstract 5
- 108091007433 antigens Proteins 0.000 abstract 5
- 241000120506 Bluetongue virus Species 0.000 abstract 3
- 241000712462 Bovine ephemeral fever virus Species 0.000 abstract 3
- 230000028993 immune response Effects 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000701083 Bovine alphaherpesvirus 1 Species 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 241001644525 Nastus productus Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- UZQJVUCHXGYFLQ-AYDHOLPZSA-N [(2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-4-[(2r,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hy Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O)O[C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O)O[C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@]([C@@]3(CC[C@H]2[C@@]1(C=O)C)C)(C)CC(O)[C@]1(CCC(CC14)(C)C)C(=O)O[C@H]1[C@@H]([C@@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O[C@H]4[C@@H]([C@@H](O[C@H]5[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O5)O)[C@H](O)[C@@H](CO)O4)O)[C@H](O)[C@@H](CO)O3)O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UZQJVUCHXGYFLQ-AYDHOLPZSA-N 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract 1
- 229930182490 saponin Natural products 0.000 abstract 1
- 150000007949 saponins Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
COMPOSIÇÃO IMUNOLÓGICA. A presente invenção refere-se a composições imunológicas compreendendo sulfolipo-ciclodextrina (SL-CD) e, saponina ou QuilA, e opcionalmente pelo menos um antígeno. A invenção refere-se a métodos e composições imunológicas compreendendo pelo menos um antígeno, que pode ser um antígeno veterinário. O antígeno veterinário nos métodos e composições imunológicas da invenção pode ser um antígeno bovino. A invenção refere-se a métodos e composições imunológicas compreendendo vírus da febre efêmera bovina (BEFV), vírus de herpes bovino 1 (IBR) ou vírus da língua azul (BTV). A invenção compreende métodos de obter uma resposta imune contra BEFV, IBR, ou BTV em um animal, que compreende administrar ao animal uma composição da invenção. Na invenção, particularmente a resposta imune é uma resposta imune protetora. A invenção compreende um método de preparar uma composição imunológica compreendendo adicionar Quil A a um vírus.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008904261A AU2008904261A0 (en) | 2008-08-19 | Immunological Composition | |
| US9209108P | 2008-08-27 | 2008-08-27 | |
| PCT/US2009/054285 WO2010022135A1 (en) | 2008-08-19 | 2009-08-19 | Immunological composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0917290A2 BRPI0917290A2 (pt) | 2015-11-10 |
| BRPI0917290A8 true BRPI0917290A8 (pt) | 2016-11-01 |
Family
ID=41696586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0917290A BRPI0917290A8 (pt) | 2008-08-19 | 2009-08-19 | Composição imunológica |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20100047279A1 (pt) |
| EP (1) | EP2331126A1 (pt) |
| JP (1) | JP2012500282A (pt) |
| KR (1) | KR101320141B1 (pt) |
| CN (1) | CN102186502B (pt) |
| AR (1) | AR076437A1 (pt) |
| AU (1) | AU2009282581B2 (pt) |
| BR (1) | BRPI0917290A8 (pt) |
| CA (1) | CA2734654C (pt) |
| CO (1) | CO6341568A2 (pt) |
| MX (1) | MX2011001910A (pt) |
| RU (1) | RU2506094C2 (pt) |
| TW (1) | TW201010719A (pt) |
| UA (1) | UA101385C2 (pt) |
| WO (1) | WO2010022135A1 (pt) |
| ZA (1) | ZA201102082B (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112012008185A2 (pt) * | 2009-10-07 | 2016-08-16 | Wyeth Llc | composições que compreendem adjuvante, macrolídeo e antígeno proteináceo, e métodos para uso dessas composições |
| RU2575599C2 (ru) * | 2010-03-12 | 2016-02-20 | Мериал Лимитед | Рекомбинантные вакцины против вируса "синего языка", их применение |
| WO2012154739A1 (en) * | 2011-05-09 | 2012-11-15 | Uwm Research Foundation, Inc. | The use of cyclodextrins in diets, water or vaccine adjuvants to boost the immune system of fish |
| CN103083658B (zh) * | 2011-10-27 | 2015-09-02 | 普莱柯生物工程股份有限公司 | 一种用于治疗或预防猪感染性疾病的疫苗佐剂组合物 |
| MX2016004961A (es) | 2013-10-17 | 2016-06-28 | Zoetis Services Llc | Procedimientos y composiciones para el tratamiento de infecciones por s. equi. |
| JP6869177B2 (ja) * | 2014-05-23 | 2021-05-12 | フィブロ アニマル ヘルス コーポレーションＰｈｉｂｒｏ Ａｎｉｍａｌ Ｈｅａｌｔｈ Ｃｏｒｐｏｒａｔｉｏｎ | 組み合わせ、組成物及び動物に組み合わせ又は組成物を投与する方法 |
| BR102021012953A2 (pt) * | 2021-06-29 | 2023-01-10 | Fabp Biotech Desenvolvimento Em Biotecnologia Ltda. | Composição de vacina veterinária contra helmintos, método para tratamento e prevenção de infecção causada por helmintos e uso |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK316188A (da) * | 1987-06-15 | 1988-12-16 | Duphar Int Res | Sulfolipopolysaccharider som stimolatorer for den ikke specifikke forsvarsmekanisme |
| GB9622159D0 (en) * | 1996-10-24 | 1996-12-18 | Solvay Sociutu Anonyme | Polyanionic polymers as adjuvants for mucosal immunization |
| AU734180B2 (en) * | 1997-08-29 | 2001-06-07 | Antigenics Llc | Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient |
| DK1104306T3 (da) * | 1998-08-10 | 2006-05-22 | Antigenics Inc | Præparater af CpG- og saponinadjuvanser og fremgangsmåder til anvendelse deraf |
| EP1104767A1 (en) * | 1999-11-30 | 2001-06-06 | Stichting Dienst Landbouwkundig Onderzoek | Mono- and disaccharide derivatives containing both fatty acid ester and sulfate ester groups |
| AU2002327338A1 (en) * | 2001-07-25 | 2003-02-17 | New York University | Use of glycosylceramides as adjuvants for vaccines against infections and cancer |
| CN1909925B (zh) * | 2004-02-20 | 2010-10-13 | 中国农业大学 | 一种免疫佐剂 |
| JP2008502605A (ja) * | 2004-06-16 | 2008-01-31 | スマート ドラッグ システムズ インコーポレイティド | 徐放性ワクチン組成物 |
| RU2288007C2 (ru) * | 2005-02-17 | 2006-11-27 | ГНУ ВНИИ ветеринарной вирусологии и микробиологии | Способ изготовления ассоциированной инактивированной культуральной вакцины против инфекционного ринотрахеита и парагриппа-3 крупного рогатого скота |
-
2009
- 2009-08-18 TW TW098127794A patent/TW201010719A/zh unknown
- 2009-08-19 CN CN200980141319.3A patent/CN102186502B/zh not_active Expired - Fee Related
- 2009-08-19 AR ARP090103175A patent/AR076437A1/es not_active Application Discontinuation
- 2009-08-19 WO PCT/US2009/054285 patent/WO2010022135A1/en not_active Ceased
- 2009-08-19 KR KR1020117006189A patent/KR101320141B1/ko not_active Expired - Fee Related
- 2009-08-19 AU AU2009282581A patent/AU2009282581B2/en not_active Ceased
- 2009-08-19 RU RU2011105863/10A patent/RU2506094C2/ru not_active IP Right Cessation
- 2009-08-19 CA CA2734654A patent/CA2734654C/en not_active Expired - Fee Related
- 2009-08-19 BR BRPI0917290A patent/BRPI0917290A8/pt not_active IP Right Cessation
- 2009-08-19 UA UAA201101661A patent/UA101385C2/ru unknown
- 2009-08-19 EP EP09791663A patent/EP2331126A1/en not_active Withdrawn
- 2009-08-19 US US12/543,536 patent/US20100047279A1/en not_active Abandoned
- 2009-08-19 MX MX2011001910A patent/MX2011001910A/es active IP Right Grant
- 2009-08-19 JP JP2011523956A patent/JP2012500282A/ja not_active Ceased
-
2011
- 2011-02-23 CO CO11022016A patent/CO6341568A2/es not_active Application Discontinuation
- 2011-03-18 ZA ZA2011/02082A patent/ZA201102082B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010022135A1 (en) | 2010-02-25 |
| KR20110044791A (ko) | 2011-04-29 |
| MX2011001910A (es) | 2011-06-20 |
| AU2009282581B2 (en) | 2013-12-19 |
| UA101385C2 (ru) | 2013-03-25 |
| EP2331126A1 (en) | 2011-06-15 |
| HK1157182A1 (en) | 2012-06-29 |
| TW201010719A (en) | 2010-03-16 |
| CA2734654A1 (en) | 2010-02-25 |
| AR076437A1 (es) | 2011-06-15 |
| CA2734654C (en) | 2015-02-10 |
| CO6341568A2 (es) | 2011-11-21 |
| AU2009282581A1 (en) | 2010-02-25 |
| US20100047279A1 (en) | 2010-02-25 |
| CN102186502A (zh) | 2011-09-14 |
| BRPI0917290A2 (pt) | 2015-11-10 |
| RU2506094C2 (ru) | 2014-02-10 |
| KR101320141B1 (ko) | 2013-11-13 |
| RU2011105863A (ru) | 2012-09-27 |
| CN102186502B (zh) | 2014-07-16 |
| ZA201102082B (en) | 2011-11-30 |
| JP2012500282A (ja) | 2012-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B25A | Requested transfer of rights approved |
Owner name: PAH W LLC (US) |
|
| B25D | Requested change of name of applicant approved |
Owner name: ZOETIS W LLC (US) |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |