BRPI0917440A2 - composições farmacêuticas oftálmicas para o tratamento de patologias neoangiogênicas do olho - Google Patents

composições farmacêuticas oftálmicas para o tratamento de patologias neoangiogênicas do olho

Info

Publication number
BRPI0917440A2
BRPI0917440A2 BRPI0917440A BRPI0917440A BRPI0917440A2 BR PI0917440 A2 BRPI0917440 A2 BR PI0917440A2 BR PI0917440 A BRPI0917440 A BR PI0917440A BR PI0917440 A BRPI0917440 A BR PI0917440A BR PI0917440 A2 BRPI0917440 A2 BR PI0917440A2
Authority
BR
Brazil
Prior art keywords
neoangiogenic
treatment
pharmaceutical compositions
eye disorders
ophthalmic pharmaceutical
Prior art date
Application number
BRPI0917440A
Other languages
English (en)
Inventor
Giuliano Francesco
Marrano Manuela
Mazzone Maria Grazia
Papa Vincenzo
Original Assignee
S I F I Societa Ind Farmaceutica Italiana S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S I F I Societa Ind Farmaceutica Italiana S P A filed Critical S I F I Societa Ind Farmaceutica Italiana S P A
Publication of BRPI0917440A2 publication Critical patent/BRPI0917440A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
BRPI0917440A 2008-08-08 2009-08-06 composições farmacêuticas oftálmicas para o tratamento de patologias neoangiogênicas do olho BRPI0917440A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08425559A EP2156834A1 (en) 2008-08-08 2008-08-08 Ophthalmic pharmaceutical compositions comprising Sorafenib for the treatment of neoangiogenic pathologies of the eye
PCT/EP2009/060197 WO2010015672A1 (en) 2008-08-08 2009-08-06 Ophthalmic pharmaceutical compositions comprising sorafenib for the treatment of neoangiogenic pathologies of the eye

Publications (1)

Publication Number Publication Date
BRPI0917440A2 true BRPI0917440A2 (pt) 2015-12-01

Family

ID=39988813

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0917440A BRPI0917440A2 (pt) 2008-08-08 2009-08-06 composições farmacêuticas oftálmicas para o tratamento de patologias neoangiogênicas do olho

Country Status (8)

Country Link
US (1) US20110142923A1 (pt)
EP (2) EP2156834A1 (pt)
JP (1) JP2011530496A (pt)
CN (1) CN102164600A (pt)
BR (1) BRPI0917440A2 (pt)
MX (1) MX2011001455A (pt)
RU (1) RU2519739C2 (pt)
WO (1) WO2010015672A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR081060A1 (es) * 2010-04-15 2012-06-06 Bayer Schering Pharma Ag Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-n-metilpiridin-2-carboxamida
EP2651403B1 (en) * 2010-12-17 2020-12-02 Glaxo Group Limited Use of lp-pla2 inhibitors in the treatment and prevention of eye diseases
CN103764118A (zh) * 2011-06-28 2014-04-30 拜尔健康护理有限责任公司 含有索拉非尼的局部眼用药用组合物
KR20160126983A (ko) * 2014-01-16 2016-11-02 온토제네시스, 엘엘씨 안내 혈관신생 및/또는 누출 치료용 조성물 및 방법
BR112017006918A2 (pt) 2014-10-09 2017-12-12 Distretto Tecnologico Sicilia Micro E Nano Sistemi S C A R L formulações nanoestruturadas para liberação de silibinina e outros ingredientes ativos para o tratamento de doenças oculares
WO2016176579A1 (en) * 2015-04-29 2016-11-03 Psivida Us, Inc. Injectable sustained release intraocular device
CA2984637A1 (en) * 2015-05-05 2016-11-10 Psivida Us, Inc. Injectable depot formulations
TWI664965B (zh) 2015-06-22 2019-07-11 新源生物科技股份有限公司 酪胺酸激酶抑制劑之眼用調配物、其使用方法、及其製備方法
WO2017027017A1 (en) * 2015-08-11 2017-02-16 Peregrine Ophthalmic PTE LTD. Stable liposomal formulations of carbonic anhydrase inhibitors for ocular drug delivery
GB2559162A (en) * 2017-01-27 2018-08-01 Univ Bradford Compound for use in medicine
CN112022848B (zh) * 2020-08-13 2022-02-22 中南大学湘雅二医院 索拉非尼在治疗1型糖尿病中的应用
WO2025169089A1 (en) 2024-02-05 2025-08-14 Sun Pharmaceutical Industries Limited Ophthalmic compositions of tyrosine kinase inhibitors and their uses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000042012A1 (en) 1999-01-13 2000-07-20 Bayer Corporation φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
CA2403612A1 (en) * 2000-03-24 2001-10-11 Romulus Kimbro Brazzell Improved treatment of neovascularization
EP2324825A1 (en) * 2002-02-11 2011-05-25 Bayer Healthcare LLC Aryl ureas with angiogenesis inhibiting activity
CN1856469B (zh) * 2003-07-23 2013-03-06 拜耳医药保健有限责任公司 用于治疗和预防疾病和疾病症状的氟代ω-羧芳基二苯基脲
EP1667721A2 (en) * 2003-09-23 2006-06-14 Novartis AG Combinations of a vegf receptor inhibitor with other therapeutic agents
US20080038316A1 (en) * 2004-10-01 2008-02-14 Wong Vernon G Conveniently implantable sustained release drug compositions
KR20080073745A (ko) * 2005-11-14 2008-08-11 바이엘 헬스케어 엘엘씨 암의 예측 및 예후 방법, 및 암 치료 요법을 모니터하는방법
EP1962842A1 (en) * 2005-12-15 2008-09-03 Bayer HealthCare AG Diaryl ureas for treating inflammatory skin, eye and/or ear diseases
EP2049084A2 (en) * 2006-07-10 2009-04-22 Elan Pharma International Limited Nanoparticulate sorafenib formulations
AU2007311092A1 (en) * 2006-10-17 2008-04-24 Dyax Corp. Sequential combination therapy

Also Published As

Publication number Publication date
JP2011530496A (ja) 2011-12-22
RU2519739C2 (ru) 2014-06-20
MX2011001455A (es) 2011-04-14
CN102164600A (zh) 2011-08-24
WO2010015672A1 (en) 2010-02-11
US20110142923A1 (en) 2011-06-16
EP2323657A1 (en) 2011-05-25
RU2011108578A (ru) 2012-09-20
EP2156834A1 (en) 2010-02-24

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL