BRPI0917975A2 - formulação de depósito de formação local injetável, processo para a preparação da referida formulação, composição farmacêutica, seringa pré-carregada, e uso de peg500 dme - Google Patents

formulação de depósito de formação local injetável, processo para a preparação da referida formulação, composição farmacêutica, seringa pré-carregada, e uso de peg500 dme

Info

Publication number
BRPI0917975A2
BRPI0917975A2 BRPI0917975A BRPI0917975A BRPI0917975A2 BR PI0917975 A2 BRPI0917975 A2 BR PI0917975A2 BR PI0917975 A BRPI0917975 A BR PI0917975A BR PI0917975 A BRPI0917975 A BR PI0917975A BR PI0917975 A2 BRPI0917975 A2 BR PI0917975A2
Authority
BR
Brazil
Prior art keywords
formulation
preparing
pharmaceutical composition
filled syringe
local formation
Prior art date
Application number
BRPI0917975A
Other languages
English (en)
Inventor
Karin Schönhammer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP08165662A external-priority patent/EP2172189A1/en
Priority claimed from EP09151917A external-priority patent/EP2213307A1/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0917975A2 publication Critical patent/BRPI0917975A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BRPI0917975A 2008-08-12 2009-08-11 formulação de depósito de formação local injetável, processo para a preparação da referida formulação, composição farmacêutica, seringa pré-carregada, e uso de peg500 dme BRPI0917975A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08162213 2008-08-12
EP08165662A EP2172189A1 (en) 2008-10-01 2008-10-01 Pharmaceutical Compositions
EP09151917A EP2213307A1 (en) 2009-02-03 2009-02-03 Injectable depot formulations
PCT/EP2009/060366 WO2010018159A1 (en) 2008-08-12 2009-08-11 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
BRPI0917975A2 true BRPI0917975A2 (pt) 2015-11-17

Family

ID=41020843

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0917975A BRPI0917975A2 (pt) 2008-08-12 2009-08-11 formulação de depósito de formação local injetável, processo para a preparação da referida formulação, composição farmacêutica, seringa pré-carregada, e uso de peg500 dme

Country Status (14)

Country Link
US (1) US9155696B2 (pt)
EP (1) EP2323623B1 (pt)
JP (2) JP5951991B2 (pt)
KR (1) KR101626632B1 (pt)
CN (1) CN102119022B (pt)
AU (1) AU2009281223B2 (pt)
BR (1) BRPI0917975A2 (pt)
CA (1) CA2731316C (pt)
ES (1) ES2600797T3 (pt)
MX (1) MX347056B (pt)
PL (1) PL2323623T3 (pt)
PT (1) PT2323623T (pt)
RU (1) RU2504360C2 (pt)
WO (1) WO2010018159A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102665401A (zh) 2009-11-16 2012-09-12 益普生制药股份有限公司 黑皮质素受体配体的药物组合物
JP6029472B2 (ja) 2010-01-13 2016-11-24 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエＩｐｓｅｎ Ｐｈａｒｍａ Ｓ．Ａ．Ｓ． ソマトスタチン類似体（アナログ）の持続的放出のための医薬組成物の製造方法
UA104945C2 (uk) * 2010-03-15 2014-03-25 Іпсен Фарма С.А.С. Фармацевтична композиція лігандів рецепторів секретагогів гормону росту
US10463607B2 (en) 2010-05-31 2019-11-05 Laboratorios Farmaceutics Rofi S.A. Antipsychotic Injectable Depot Composition
SI2394664T1 (sl) * 2010-05-31 2016-10-28 Laboratorios Farmaceuticos Rovi, S.A. Antipsihotični depojski sestavek za injiciranje
WO2014049073A1 (en) * 2012-09-27 2014-04-03 Octapharma Ag Test for hemolytic potential of pharmaceutical products and formulations for risk minimization
BR112015016264A2 (pt) * 2013-03-14 2017-07-11 Genzyme Corp composições de crescimento ósseo termo-sensível
EP2823808A1 (en) 2013-07-09 2015-01-14 Ipsen Pharma S.A.S. Pharmaceutical composition for a sustained release of lanreotide
WO2015133580A1 (ja) * 2014-03-05 2015-09-11 わかもと製薬株式会社 注入可能なポリ乳酸類含有組成物
JO3394B1 (ar) 2014-07-04 2019-10-20 Osteo Pharma B V تركيبات ومنتجات للاستعمال في علاج كسور وعيوب العظام
JP6949820B2 (ja) 2015-08-03 2021-10-13 トルマー インターナショナル リミテッド 薬物の持続投与のための液体ポリマー送達システム
TWI798161B (zh) 2015-09-21 2023-04-11 瑞士商梯瓦製藥國際有限公司 持續釋放的奧氮平調配物
GB201519811D0 (en) * 2015-11-10 2015-12-23 Univ Belfast Ocular compositions
CN106822043A (zh) * 2017-01-24 2017-06-13 广州帝奇医药技术有限公司 利培酮缓释组合物及其制备方法
AU2018238136A1 (en) 2017-03-20 2019-11-07 Teva Pharmaceuticals International Gmbh Sustained release olanzapine formulations
US11167034B2 (en) * 2017-06-13 2021-11-09 The University Of British Columbia Polymeric paste compositions for drug delivery
CN107595765A (zh) 2017-09-22 2018-01-19 沈阳兴齐眼药股份有限公司 一种眼用缓释药物递送系统及其制备方法
WO2020065401A1 (en) * 2018-09-25 2020-04-02 Tolmar International, Ltd. Liquid polymer delivery system for extended administration of drugs
CA3197170A1 (en) * 2020-09-30 2022-04-07 Tolmar International Limited Biodegradable polymer and solvent compositions and systems for extended storage and delivery of active pharmaceutical ingredients
WO2022153262A1 (en) 2021-01-18 2022-07-21 Anton Frenkel Pharmaceutical dosage form
WO2022251137A1 (en) * 2021-05-24 2022-12-01 The Regents Of The University Of California Thermoreversible polymers and methods of use thereof
AU2022308198A1 (en) 2021-07-06 2024-02-01 Mark Hasleton Treatment of serotonin reuptake inhibitor withdrawal syndrome
US12318387B2 (en) 2021-07-16 2025-06-03 Laboratorios Farmaceuticos Rovi, S.A. Method of treating acute exacerbation of schizophrenia with long-acting injectable depot composition
TW202313047A (zh) 2021-09-21 2023-04-01 西班牙商禾霏藥品實驗室有限公司 抗精神病可注射儲積型組合物
EP4527389A1 (en) 2022-05-18 2025-03-26 Laboratorios Farmacéuticos Rovi S.A. Prolonged-release injectable compositions for use in treatment with risperidone together with cyp2d6 enzyme inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020164374A1 (en) * 1997-10-29 2002-11-07 John Jackson Polymeric systems for drug delivery and uses thereof
KR100416242B1 (ko) 1999-12-22 2004-01-31 주식회사 삼양사 약물전달체용 생분해성 블록 공중합체의 액체 조성물 및이의 제조방법
KR100446101B1 (ko) 2000-12-07 2004-08-30 주식회사 삼양사 수난용성 약물의 서방성 제형 조성물
WO2003045351A1 (en) 2001-11-30 2003-06-05 Pfizer Inc. Controlled release polymeric compositions of bone growth promoting compounds
GB0412866D0 (en) * 2004-06-09 2004-07-14 Novartis Ag Organic compounds
MX2007001760A (es) * 2004-08-12 2007-07-24 Quest Pharmaceutical Services Composiciones farmaceuticas para la distribucion de liberacion controlada de compuestos biologicamente activos.
US20070149631A1 (en) 2005-12-22 2007-06-28 Haider Karl W Base-catalyzed alkoxylation in the presense of polyoxyethylene-containing compounds

Also Published As

Publication number Publication date
US9155696B2 (en) 2015-10-13
ES2600797T3 (es) 2017-02-10
EP2323623A1 (en) 2011-05-25
PL2323623T3 (pl) 2017-04-28
CA2731316A1 (en) 2010-02-18
KR101626632B1 (ko) 2016-06-01
JP2015129145A (ja) 2015-07-16
CN102119022A (zh) 2011-07-06
EP2323623B1 (en) 2016-07-27
MX2011001660A (es) 2011-03-25
JP2011530568A (ja) 2011-12-22
KR20110042309A (ko) 2011-04-26
JP5951991B2 (ja) 2016-07-13
RU2504360C2 (ru) 2014-01-20
AU2009281223A1 (en) 2010-02-18
PT2323623T (pt) 2016-11-04
CN102119022B (zh) 2015-09-09
WO2010018159A1 (en) 2010-02-18
AU2009281223B2 (en) 2014-01-09
CA2731316C (en) 2017-10-03
RU2011108666A (ru) 2012-09-20
MX347056B (es) 2017-04-10
US20110183905A1 (en) 2011-07-28

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

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