BRPI0918142A2 - composição farmaclógica tópica, seu método de preparação, bem como uso da forma de ácido livre de ácido 2-(4-isobutifilfenil)prpiônico - Google Patents

composição farmaclógica tópica, seu método de preparação, bem como uso da forma de ácido livre de ácido 2-(4-isobutifilfenil)prpiônico

Info

Publication number
BRPI0918142A2
BRPI0918142A2 BRPI0918142A BRPI0918142A BRPI0918142A2 BR PI0918142 A2 BRPI0918142 A2 BR PI0918142A2 BR PI0918142 A BRPI0918142 A BR PI0918142A BR PI0918142 A BRPI0918142 A BR PI0918142A BR PI0918142 A2 BRPI0918142 A2 BR PI0918142A2
Authority
BR
Brazil
Prior art keywords
isobutyphylphenyl
preparation
well
propionic acid
free form
Prior art date
Application number
BRPI0918142A
Other languages
English (en)
Inventor
Diane L Kozwich
Kanu Patel
Stephen G Carter
Zhen Zhu
Original Assignee
Biochemics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemics Inc filed Critical Biochemics Inc
Publication of BRPI0918142A2 publication Critical patent/BRPI0918142A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
BRPI0918142A 2008-09-10 2009-09-10 composição farmaclógica tópica, seu método de preparação, bem como uso da forma de ácido livre de ácido 2-(4-isobutifilfenil)prpiônico BRPI0918142A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9567208P 2008-09-10 2008-09-10
PCT/US2009/056568 WO2010030821A2 (en) 2008-09-10 2009-09-10 Ibuprofen for topical administration

Publications (1)

Publication Number Publication Date
BRPI0918142A2 true BRPI0918142A2 (pt) 2015-12-01

Family

ID=41447140

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0918142A BRPI0918142A2 (pt) 2008-09-10 2009-09-10 composição farmaclógica tópica, seu método de preparação, bem como uso da forma de ácido livre de ácido 2-(4-isobutifilfenil)prpiônico

Country Status (6)

Country Link
US (4) US20100137443A1 (pt)
EP (2) EP2373346B1 (pt)
AU (1) AU2009291755B2 (pt)
BR (1) BRPI0918142A2 (pt)
CA (2) CA2726726A1 (pt)
WO (1) WO2010030821A2 (pt)

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CA2726726A1 (en) 2008-09-10 2010-03-18 Thrubit B.V. Ibuprofen for topical administration
US9566256B2 (en) 2008-09-22 2017-02-14 Biochemics, Inc. Transdermal drug delivery using an osmolyte and vasoactive agent
ES2541483T3 (es) * 2009-12-16 2015-07-21 Shasun Pharmaceuticals Limited Composición de hidrogel transdérmico de dexibuprofeno
CN102854263B (zh) * 2012-08-31 2014-04-16 石家庄中硕药业集团有限公司 一种同时测定布洛芬注射液中布洛芬及精氨酸含量的方法
US10596117B1 (en) 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds
US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
US11007161B1 (en) * 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
WO2016137411A1 (en) 2015-02-25 2016-09-01 Pharmactive İlaç Sanayi Ve Ticaret A. Ş. Topical spray composition comprising ibuprofen and lidocaine
GB2546513B (en) * 2016-01-20 2020-09-16 Cubic Pharmaceuticals Ltd Process of preparing active pharmaceutical ingredient salts
CA3063870A1 (en) 2017-05-15 2018-11-22 Biochemics, Inc. Transdermally-delivered combination drug therapy for pain
CA3078545A1 (en) 2017-10-06 2019-04-11 Cargill, Incorporated Stabilized steviol glycoside compositions and uses thereof
US12246098B2 (en) 2018-09-27 2025-03-11 BioPhysics Pharma, Inc. Trans-epithelial membrane drug delivery system
MX2021002833A (es) 2018-09-27 2021-05-27 Biophysics Pharma Inc Sistema de suministro de farmaco transdermico.
US11504327B1 (en) 2019-01-21 2022-11-22 Eric Morrison Method of preparing nanoparticles by hot-melt extrusion
CN113784629B (zh) 2019-04-06 2024-12-27 嘉吉公司 用于制备植物提取物组合物的方法

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US4440777A (en) 1981-07-07 1984-04-03 Merck & Co., Inc. Use of eucalyptol for enhancing skin permeation of bio-affecting agents
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Also Published As

Publication number Publication date
EP3574921A1 (en) 2019-12-04
US20200009095A1 (en) 2020-01-09
AU2009291755A1 (en) 2010-03-18
AU2009291755B2 (en) 2016-04-21
WO2010030821A3 (en) 2011-01-20
CA2749941A1 (en) 2010-03-18
EP2373346A2 (en) 2011-10-12
US20170095433A1 (en) 2017-04-06
US20100137443A1 (en) 2010-06-03
CA2726726A1 (en) 2010-03-18
WO2010030821A2 (en) 2010-03-18
CA2749941C (en) 2018-04-24
EP2373346B1 (en) 2019-06-12
US9561174B2 (en) 2017-02-07
US20120329875A1 (en) 2012-12-27

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2383 DE 06-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.