BRPI0920482A2 - método para produção de insulina recombinante humana - Google Patents

método para produção de insulina recombinante humana

Info

Publication number: BRPI0920482A2
Authority: BR; Brazil
Prior art keywords: recombinant human; human insulin; producing recombinant; producing; insulin
Prior art date: 2008-11-26

Application number

BRPI0920482-2A

Other languages

English (en)

Inventor

Pavlovichi Lazaryev Aleksey

Evgenievich Kostetskii Igor

Leonidovich Lisovskyy Igor

Pavlovich Lesik Igor

Romanovich Luciv Vladimir

Original Assignee

Llc Mako

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-11-26

Filing date

2009-06-16

Publication date

2019-09-24

2009-06-16 Application filed by Llc Mako filed Critical Llc Mako

2019-09-24 Publication of BRPI0920482A2 publication Critical patent/BRPI0920482A2/pt

Links

101000976075 Homo sapiens Insulin Proteins 0.000 title 1
PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

BRPI0920482-2A 2008-11-26 2009-06-16 método para produção de insulina recombinante humana BRPI0920482A2 (pt)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
UAA200813678		2008-11-26
UAA200813678A UA91281C2 (ru)	2008-11-26	2008-11-26	Способ получения рекомбинантного инсулина человека
PCT/UA2009/000025 WO2010062279A1 (ru)	2008-11-26	2009-06-16	Способ получения рекомбинантного инсулина человека

Publications (1)

Publication Number	Publication Date
BRPI0920482A2 true BRPI0920482A2 (pt)	2019-09-24

Family

ID=42225939

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0920482-2A BRPI0920482A2 (pt)	2008-11-26	2009-06-16	método para produção de insulina recombinante humana

Country Status (8)

Country	Link
US (1)	US20120058513A1 (pt)
EP (1)	EP2374888A4 (pt)
CN (1)	CN102282260A (pt)
BR (1)	BRPI0920482A2 (pt)
CA (1)	CA2746984A1 (pt)
EA (1)	EA201100781A1 (pt)
UA (1)	UA91281C2 (pt)
WO (1)	WO2010062279A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2447149C1 (ru) *	2011-03-24	2012-04-10	Винсорт Менеджемент Инк	РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pMSIN4, КОДИРУЮЩАЯ ГИБРИДНЫЙ ПОЛИПЕПТИД - ПРЕДШЕСТВЕННИК ИНСУЛИНА ЧЕЛОВЕКА, ШТАММ BL21(DE3)/pMSIN4-ПРОДУЦЕНТ РЕКОМБИНАНТНОГО ИНСУЛИНА ЧЕЛОВЕКА, СПОСОБ ПОЛУЧЕНИЯ РЕКОМБИНАНТНОГО ИНСУЛИНА ЧЕЛОВЕКА
WO2012152439A1 (en) *	2011-05-10	2012-11-15	Glucometrix Ag	Comprehensive buffer system for renaturing human proinsulin or proinsulin derivatives
US10421795B2 (en) *	2012-12-17	2019-09-24	Merck Sharp & Dohme Corp.	Process for purifying insulin and analogues thereof
JP2016523241A (ja)	2013-06-14	2016-08-08	プレジデントアンドフェローズオブハーバードカレッジ	安定化されたポリペプチドインスリン受容体調節剤
US20150165341A1 (en) *	2013-10-30	2015-06-18	NorthStar Medical Radionuclides LLC	Separator cartridge for radionuclide
CN103694339B (zh) *	2013-12-04	2017-10-13	珠海联邦制药股份有限公司	一种甘精胰岛素前体的复性方法
US10562951B2 (en) *	2015-03-10	2020-02-18	Merck Sharp & Dohme Corp.	Process for preparing recombinant insulin using microfiltration
KR20170036643A (ko) *	2015-09-24	2017-04-03	한미약품 주식회사	인슐린의 제조 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4405179A1 (de) *	1994-02-18	1995-08-24	Hoechst Ag	Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken
KR100253916B1 (ko) *	1997-12-29	2000-05-01	김충환	사람 인슐린 전구체의 제조방법
AU2003280870A1 (en) *	2002-11-12	2004-06-03	Ckd Bio Corp.	Plasmids expressing human insulin and the preparation method for human insuling thereby
UA76661C2 (en)	2005-04-06	2006-08-15	Omakooe Ltd Liability Company	A method for producing recombinant humanæs insulin

2008
- 2008-11-26 UA UAA200813678A patent/UA91281C2/ru unknown
2009
- 2009-06-16 EP EP09829420A patent/EP2374888A4/en not_active Withdrawn
- 2009-06-16 CA CA2746984A patent/CA2746984A1/en not_active Abandoned
- 2009-06-16 EA EA201100781A patent/EA201100781A1/ru unknown
- 2009-06-16 CN CN2009801545154A patent/CN102282260A/zh active Pending
- 2009-06-16 BR BRPI0920482-2A patent/BRPI0920482A2/pt not_active IP Right Cessation
- 2009-06-16 WO PCT/UA2009/000025 patent/WO2010062279A1/ru not_active Ceased
2011
- 2011-05-26 US US13/116,822 patent/US20120058513A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2010062279A1 (ru)	2010-06-03
EP2374888A1 (en)	2011-10-12
US20120058513A1 (en)	2012-03-08
EA201100781A1 (ru)	2012-01-30
EP2374888A4 (en)	2012-06-06
CN102282260A (zh)	2011-12-14
UA91281C2 (ru)	2010-07-12
CA2746984A1 (en)	2010-06-03

Legal Events

Date	Code	Title	Description
2011-11-22	B15V	Prolongation of time limit allowed	Free format text: CONFORME SOLICITADO NA PETICAO NO 018110028459/SP DE 26/07/2011.
2019-10-01	B08F	Application fees: application dismissed [chapter 8.6 patent gazette]
2020-01-21	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

Publication	Publication Date	Title
NO2024044I1 (no)	2024-10-08	Insulin icodec
BR112012004707A2 (pt)	2016-04-12	método
BRPI0919116A2 (pt)	2015-12-08	método
FI20090389A0 (fi)	2009-10-23	Menetelmä
ES2829950T8 (es)	2021-06-10	Procedimiento para producir componentes endurecidos
BRPI0916152A2 (pt)	2015-11-10	aparelho para via aérea melhorado
BR112012000623A2 (pt)	2016-02-10	composição de emulsão estabilizada, método, e, método para preparar uma composição de emulsão estabilizada
DK2408807T3 (da)	2021-08-09	Fremgangsmåde til terapeutisk anvendelse
BRPI0922490A2 (pt)	2015-08-04	Método para produção de beta-santaleno
BRPI0911077A2 (pt)	2015-12-29	método para tratamento de biomassa
DK2313489T3 (da)	2015-06-22	Fremstillingsmetode
BRPI1012526A2 (pt)	2016-03-29	método
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BRPI1010705A2 (pt)	2015-09-15	método
BRPI0813858A2 (pt)	2015-01-06	Método para produzir peptídeo
BRPI0920482A2 (pt)	2019-09-24	método para produção de insulina recombinante humana
BRPI0917684A2 (pt)	2015-12-01	método terapêutico homeopático
BRPI1011722A2 (pt)	2016-03-22	método de fabricação de calçados
BRPI1012532A2 (pt)	2016-03-29	método
BRPI0810171A2 (pt)	2014-12-30	Método para o aumento da secreção de insulina
IL209167A0 (en)	2011-01-31	Protein refolding method
EP2324768A4 (en)	2013-01-16	TOMOGRAPHIC PROCEDURE
BRPI1011870A2 (pt)	2016-03-29	método para a produção de uma vidraça com reflexão reduzida, vidraça, e, uso de uma vidraça
BRPI0916597A2 (pt)	2015-08-04	Método
BRPI1009350A2 (pt)	2016-03-08	método