BRPI0920524A2 - método de purificação - Google Patents

método de purificação

Info

Publication number
BRPI0920524A2
BRPI0920524A2 BRPI0920524A BRPI0920524A BRPI0920524A2 BR PI0920524 A2 BRPI0920524 A2 BR PI0920524A2 BR PI0920524 A BRPI0920524 A BR PI0920524A BR PI0920524 A BRPI0920524 A BR PI0920524A BR PI0920524 A2 BRPI0920524 A2 BR PI0920524A2
Authority
BR
Brazil
Prior art keywords
purification method
purification
Prior art date
Application number
BRPI0920524A
Other languages
English (en)
Inventor
Anna Kabanova
Francesco Berti
Maria Rosaria Romano
Paolo Costantino
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0920524A2 publication Critical patent/BRPI0920524A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
BRPI0920524A 2008-10-27 2009-10-27 método de purificação BRPI0920524A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10876308P 2008-10-27 2008-10-27
PCT/IB2009/007346 WO2010049806A1 (en) 2008-10-27 2009-10-27 Purification method

Publications (1)

Publication Number Publication Date
BRPI0920524A2 true BRPI0920524A2 (pt) 2015-12-22

Family

ID=41692891

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0920524A BRPI0920524A2 (pt) 2008-10-27 2009-10-27 método de purificação

Country Status (16)

Country Link
US (1) US11065323B2 (pt)
EP (1) EP2349520B1 (pt)
JP (1) JP5689064B2 (pt)
CN (1) CN102264444B (pt)
AU (1) AU2009309416B2 (pt)
BR (1) BRPI0920524A2 (pt)
CA (1) CA2777837C (pt)
CY (1) CY1117906T1 (pt)
DK (1) DK2349520T3 (pt)
ES (1) ES2586308T3 (pt)
HR (1) HRP20160815T1 (pt)
HU (1) HUE029265T2 (pt)
PL (1) PL2349520T3 (pt)
PT (1) PT2349520T (pt)
SI (1) SI2349520T1 (pt)
WO (1) WO2010049806A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114025789A (zh) 2019-04-02 2022-02-08 Vaxcyte公司 侵入质粒抗原b的经优化的无细胞合成和有关的组合物及使用方法
TW202136285A (zh) 2020-02-18 2021-10-01 美商Ｖａｘｃｙｔｅ公司 含有多醣-蛋白質結合物之a型鏈球菌免疫原性組合物
IL305201A (en) * 2021-02-17 2023-10-01 Vaxcyte Inc Methods for the distillation of polysaccharides and their polypeptide conjugates

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Also Published As

Publication number Publication date
US11065323B2 (en) 2021-07-20
CN102264444A (zh) 2011-11-30
DK2349520T3 (en) 2016-08-15
ES2586308T3 (es) 2016-10-13
US20120010398A1 (en) 2012-01-12
AU2009309416B2 (en) 2015-05-28
HRP20160815T1 (hr) 2016-09-23
JP2012506853A (ja) 2012-03-22
EP2349520B1 (en) 2016-05-25
WO2010049806A1 (en) 2010-05-06
CA2777837A1 (en) 2010-05-06
PT2349520T (pt) 2016-08-16
CY1117906T1 (el) 2017-05-17
SI2349520T1 (sl) 2016-08-31
EP2349520A1 (en) 2011-08-03
HUE029265T2 (en) 2017-02-28
CN102264444B (zh) 2015-08-05
AU2009309416A1 (en) 2010-05-06
CA2777837C (en) 2017-07-11
JP5689064B2 (ja) 2015-03-25
PL2349520T3 (pl) 2017-08-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]