BRPI0920695A2 - detecção de ácido nucleico npm1 em fluidos corpóreos acelulares - Google Patents

detecção de ácido nucleico npm1 em fluidos corpóreos acelulares

Info

Publication number
BRPI0920695A2
BRPI0920695A2 BRPI0920695A BRPI0920695A BRPI0920695A2 BR PI0920695 A2 BRPI0920695 A2 BR PI0920695A2 BR PI0920695 A BRPI0920695 A BR PI0920695A BR PI0920695 A BRPI0920695 A BR PI0920695A BR PI0920695 A2 BRPI0920695 A2 BR PI0920695A2
Authority
BR
Brazil
Prior art keywords
nucleic acid
body fluids
acid detection
acellular body
npm1 nucleic
Prior art date
Application number
BRPI0920695A
Other languages
English (en)
Inventor
Maher Albitar
Original Assignee
Quest Diagnostics Investiments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quest Diagnostics Investiments Inc filed Critical Quest Diagnostics Investiments Inc
Publication of BRPI0920695A2 publication Critical patent/BRPI0920695A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0920695A 2008-10-17 2009-10-14 detecção de ácido nucleico npm1 em fluidos corpóreos acelulares BRPI0920695A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10653208P 2008-10-17 2008-10-17
US11094108P 2008-11-03 2008-11-03
US12/336,475 US20100099084A1 (en) 2008-10-17 2008-12-16 Detection of npm1 nucleic acid in acellular body fluids
PCT/US2009/060672 WO2010045354A1 (en) 2008-10-17 2009-10-14 Detection of npm1 nucleic acid in acellular body fluids

Publications (1)

Publication Number Publication Date
BRPI0920695A2 true BRPI0920695A2 (pt) 2016-01-12

Family

ID=42106876

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0920695A BRPI0920695A2 (pt) 2008-10-17 2009-10-14 detecção de ácido nucleico npm1 em fluidos corpóreos acelulares

Country Status (8)

Country Link
US (1) US20100099084A1 (pt)
EP (1) EP2337867A4 (pt)
JP (1) JP2012505655A (pt)
CN (1) CN102186995A (pt)
BR (1) BRPI0920695A2 (pt)
CA (1) CA2740230A1 (pt)
MX (1) MX2011004058A (pt)
WO (1) WO2010045354A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101955994B (zh) * 2010-06-17 2013-01-23 江苏迈迪基因生物科技有限公司 Npm1基因突变的联合检测方法及诊断试剂盒
CA2818684C (en) * 2010-11-22 2023-02-21 Innate Pharma Sa Nk cell modulating treatments and methods for treatment of hematological malignancies
KR101660322B1 (ko) * 2011-04-28 2016-09-29 아크레이 가부시키가이샤 ＮＰＭ1 유전자의 ｅｘｏｎ12 변이의 검출용 프로브 및 그 용도
GB201116131D0 (en) * 2011-09-19 2011-11-02 Epistem Ltd Probe
CN103103251A (zh) * 2011-11-15 2013-05-15 中山大学达安基因股份有限公司 荧光pcr毛细管电泳检测flt3-itd基因突变的试剂盒
CN102382896A (zh) * 2011-12-06 2012-03-21 苏州苏大赛尔免疫生物技术有限公司 Npm1基因突变检测方法及其试剂盒
IL294449B2 (en) 2015-03-31 2024-05-01 Syros Pharmaceuticals Inc Methods for stratifying patients for treatment with retinoic acid alpha receptor agonists
US9868994B2 (en) 2016-04-08 2018-01-16 Syros Pharmaceuticals, Inc. Methods of stratifying patients for treatment with retinoic acid receptor-α agonists
CN105950775B (zh) * 2016-07-08 2019-06-11 中山大学达安基因股份有限公司 一种检测npm1基因突变分型的试剂盒
CN111868254A (zh) * 2018-04-09 2020-10-30 深圳华大生命科学研究院 基因文库的构建方法及其应用
CN110669840B (zh) * 2019-10-30 2021-03-19 宁波胤瑞生物医学仪器有限责任公司 一种npm1突变检测试剂盒
CN113637751A (zh) * 2021-07-16 2021-11-12 暨南大学 Tnfaip3非编码序列突变检测试剂在制备预测t细胞淋巴瘤预后试剂盒中的应用
CN117795091A (zh) * 2021-08-05 2024-03-29 香港大学 用于快速多重筛选和监测npm1突变的组合物和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001230A (en) * 1988-04-29 1999-12-14 Beckman Coulter, Inc. Automated capillary electrophoresis apparatus
US5639611A (en) * 1988-12-12 1997-06-17 City Of Hope Allele specific polymerase chain reaction
US5223391A (en) * 1990-02-21 1993-06-29 President And Fellows Of Harvard College Inhibitors of herpes simplex virus replication
CA2094343A1 (en) * 1992-07-17 1994-01-18 Gerald L. Klein Method and apparatus for displaying capillary electrophoresis data
US6217731B1 (en) * 1998-10-21 2001-04-17 Spectrumedix Corporation Method and apparatus for monitoring and displaying the status of a parallel capillary electrophoresis device
JP2007236253A (ja) * 2006-03-07 2007-09-20 Toray Ind Inc 疾患又は疾患マーカーの検出方法
US20070248961A1 (en) * 2006-04-20 2007-10-25 Maher Albitar Methods for detecting mutations in JAK2 nucleic acid

Also Published As

Publication number Publication date
EP2337867A4 (en) 2012-10-24
WO2010045354A1 (en) 2010-04-22
MX2011004058A (es) 2011-08-12
CN102186995A (zh) 2011-09-14
CA2740230A1 (en) 2010-04-22
EP2337867A1 (en) 2011-06-29
US20100099084A1 (en) 2010-04-22
JP2012505655A (ja) 2012-03-08

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Legal Events

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B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.