BRPI0922152A2 - Compostos - Google Patents

Compostos

Info

Publication number: BRPI0922152A2
Authority: BR; Brazil
Prior art keywords: compounds
Prior art date: 2008-12-01

Application number

BRPI0922152-2A

Other languages

English (en)

Inventor

Srinivisa Rao Akireddy

Balwinder Singh Bhatti

Timothy J Cuthbertson

Craig Harrison Miller

Joseph Pike Mitchener Jr

Original Assignee

Targacept Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-01

Filing date

2009-11-30

Publication date

2015-08-18

2009-11-30 Application filed by Targacept Inc filed Critical Targacept Inc

2015-08-18 Publication of BRPI0922152A2 publication Critical patent/BRPI0922152A2/pt

Links

150000001875 compounds Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Virology (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Pyridine Compounds (AREA)

BRPI0922152-2A 2008-12-01 2009-11-30 Compostos BRPI0922152A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11888508P	2008-12-01	2008-12-01
PCT/US2009/066083 WO2010065447A2 (en)	2008-12-01	2009-11-30	Novel compounds

Publications (1)

Publication Number	Publication Date
BRPI0922152A2 true BRPI0922152A2 (pt)	2015-08-18

Family

ID=41549744

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BRPI0922630A BRPI0922630A2 (pt)	2008-12-01	2009-11-30	"(r)-3-(e)-2-(pirrolidin-33-il)vinil)-5-(tetra-hidropiran-4-ilóxi)piridina, seus sais, suas sínteses e seus usos como ligantes para receptores acetilcolinérgico nicotínicos"
BRPI0922152-2A BRPI0922152A2 (pt)	2008-12-01	2009-11-30	Compostos

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
BRPI0922630A BRPI0922630A2 (pt)	2008-12-01	2009-11-30	"(r)-3-(e)-2-(pirrolidin-33-il)vinil)-5-(tetra-hidropiran-4-ilóxi)piridina, seus sais, suas sínteses e seus usos como ligantes para receptores acetilcolinérgico nicotínicos"

Country Status (27)

Country	Link
US (3)	US8633227B2 (pt)
EP (3)	EP2896619A1 (pt)
JP (2)	JP5615836B2 (pt)
KR (2)	KR20110094318A (pt)
CN (2)	CN102227406B (pt)
AR (1)	AR074239A1 (pt)
AU (2)	AU2009322628A1 (pt)
BR (2)	BRPI0922630A2 (pt)
CA (2)	CA2744197A1 (pt)
CL (2)	CL2009002146A1 (pt)
CO (1)	CO6382158A2 (pt)
EA (1)	EA021054B1 (pt)
EC (1)	ECSP11011135A (pt)
ES (1)	ES2403022T3 (pt)
IL (2)	IL212799A (pt)
MX (2)	MX2011005712A (pt)
MY (1)	MY159040A (pt)
NZ (1)	NZ593058A (pt)
PE (1)	PE20100467A1 (pt)
RU (1)	RU2507197C2 (pt)
SA (1)	SA109300715B1 (pt)
SG (2)	SG171876A1 (pt)
TW (1)	TW201024283A (pt)
UA (1)	UA106217C2 (pt)
UY (1)	UY32278A (pt)
WO (2)	WO2010065449A1 (pt)
ZA (1)	ZA201103497B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL266097B (en) *	2008-12-01	2022-07-01	Oyster Point Pharma Inc	Mono-orotate acid addition salt of r(–5–)–e(–2–)pyrrolidine––3ylvinyl)pyrimidine
US9145396B2 (en)	2008-12-01	2015-09-29	Targacept, Inc.	Synthesis and novel salt forms of (R)-5-((E)-2-pyrrolidin-3ylvinyl)pyrimidine
US20130196340A1 (en) *	2012-01-30	2013-08-01	Roar Holding Llc	Ex vivo plasma enzyme activity assay using inhibitors as a negative control
PE20151301A1 (es)	2013-02-05	2015-09-16	Purdue Pharma Lp	Formulaciones farmaceuticas resistentes a la manipulacion indebida
US20160262372A1 (en) *	2015-03-13	2016-09-15	Cornell Kunz	Extermination Treatment Appliance And Method
NZ746468A (en)	2016-04-07	2023-06-30	Oyster Point Pharma Inc	Methods of treating ocular conditions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK94393A3 (en) *	1992-09-11	1994-08-10	Thomae Gmbh Dr K	Cyclic derivatives of urea, process for their production and their pharmaceutical agents with the content of those
IL107184A (en)	1992-10-09	1997-08-14	Abbott Lab	Heterocyclic ether compounds that enhance cognitive function
US5852041A (en)	1993-04-07	1998-12-22	Sibia Neurosciences, Inc.	Substituted pyridines useful as modulators of acethylcholine receptors
US5597919A (en)	1995-01-06	1997-01-28	Dull; Gary M.	Pyrimidinyl or Pyridinyl alkenyl amine compounds
US5604231A (en)	1995-01-06	1997-02-18	Smith; Carr J.	Pharmaceutical compositions for prevention and treatment of ulcerative colitis
JP3745433B2 (ja) *	1995-02-02	2006-02-15	第一製薬株式会社	複素環式化合物
US5585388A (en)	1995-04-07	1996-12-17	Sibia Neurosciences, Inc.	Substituted pyridines useful as modulators of acetylcholine receptors
US5583140A (en)	1995-05-17	1996-12-10	Bencherif; Merouane	Pharmaceutical compositions for the treatment of central nervous system disorders
IL118279A (en)	1995-06-07	2006-10-05	Abbott Lab	Compounds 3 - Pyridyloxy (or Thio) Alkyl Heterocyclic Pharmaceutical Compositions Containing Them and Their Uses for Preparing Drugs to Control Synaptic Chemical Transmission
CA2264569C (en) *	1996-09-13	2003-11-11	Schering Corporation	Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
TW492957B (en) *	1996-11-07	2002-07-01	Novartis Ag	N-substituted 2-cyanopyrrolidnes
ZA9711092B (en)	1996-12-11	1999-07-22	Smithkline Beecham Corp	Novel compounds.
JPH1171345A (ja) *	1997-08-30	1999-03-16	Nippon Nohyaku Co Ltd	光学活性なピロリジン誘導体及びその中間体並びにそれらの製造法
US6310043B1 (en)	1998-08-07	2001-10-30	Governors Of The University Of Alberta	Treatment of bacterial infections
GB9821503D0 (en)	1998-10-02	1998-11-25	Novartis Ag	Organic compounds
EP1302458A4 (en) *	2000-07-11	2005-10-19	Banyu Pharma Co Ltd	ESTERDERIVATE
WO2003013526A1 (en) *	2001-08-08	2003-02-20	Merck & Co. Inc.	Anticoagulant compounds
US7098331B2 (en) *	2003-03-05	2006-08-29	Targacept, Inc.	Arylvinylazacycloalkane compounds and methods of preparation and use thereof
WO2007054777A1 (en) *	2005-11-09	2007-05-18	Orchid Chemicals & Pharmaceuticals Limited	Depletion of isomer in cephalosporin antibiotic
AU2007249194B2 (en) *	2006-05-12	2012-11-22	Myrexis, Inc.	Therapeutic compounds and their use in cancer

2009
- 2009-11-25 TW TW098140046A patent/TW201024283A/zh unknown
- 2009-11-30 AU AU2009322628A patent/AU2009322628A1/en not_active Abandoned
- 2009-11-30 EA EA201170736A patent/EA021054B1/ru not_active IP Right Cessation
- 2009-11-30 EP EP14191551.2A patent/EP2896619A1/en not_active Withdrawn
- 2009-11-30 CA CA2744197A patent/CA2744197A1/en not_active Abandoned
- 2009-11-30 AR ARP090104608A patent/AR074239A1/es not_active Application Discontinuation
- 2009-11-30 NZ NZ593058A patent/NZ593058A/xx not_active IP Right Cessation
- 2009-11-30 CL CL2009002146A patent/CL2009002146A1/es unknown
- 2009-11-30 EP EP09775409A patent/EP2358670B1/en active Active
- 2009-11-30 US US13/125,892 patent/US8633227B2/en not_active Expired - Fee Related
- 2009-11-30 MY MYPI2011002085A patent/MY159040A/en unknown
- 2009-11-30 BR BRPI0922630A patent/BRPI0922630A2/pt not_active IP Right Cessation
- 2009-11-30 CN CN2009801478569A patent/CN102227406B/zh not_active Expired - Fee Related
- 2009-11-30 CN CN200980148072.8A patent/CN102232072B/zh not_active Expired - Fee Related
- 2009-11-30 UY UY0001032278A patent/UY32278A/es not_active Application Discontinuation
- 2009-11-30 AU AU2009322630A patent/AU2009322630A1/en not_active Abandoned
- 2009-11-30 PE PE2009001282A patent/PE20100467A1/es not_active Application Discontinuation
- 2009-11-30 US US13/130,954 patent/US8153821B2/en active Active
- 2009-11-30 CL CL2009002145A patent/CL2009002145A1/es unknown
- 2009-11-30 SG SG2011039575A patent/SG171876A1/en unknown
- 2009-11-30 WO PCT/US2009/066092 patent/WO2010065449A1/en not_active Ceased
- 2009-11-30 RU RU2011127004/04A patent/RU2507197C2/ru active IP Right Revival
- 2009-11-30 EP EP09775410A patent/EP2358705A1/en not_active Withdrawn
- 2009-11-30 CA CA2744191A patent/CA2744191A1/en not_active Abandoned
- 2009-11-30 KR KR1020117014805A patent/KR20110094318A/ko not_active Ceased
- 2009-11-30 JP JP2011538713A patent/JP5615836B2/ja not_active Expired - Fee Related
- 2009-11-30 JP JP2011538712A patent/JP5698673B2/ja not_active Expired - Fee Related
- 2009-11-30 SG SG2011038528A patent/SG171432A1/en unknown
- 2009-11-30 KR KR1020117014918A patent/KR20110094100A/ko not_active Abandoned
- 2009-11-30 BR BRPI0922152-2A patent/BRPI0922152A2/pt not_active IP Right Cessation
- 2009-11-30 MX MX2011005712A patent/MX2011005712A/es not_active Application Discontinuation
- 2009-11-30 ES ES09775409T patent/ES2403022T3/es active Active
- 2009-11-30 WO PCT/US2009/066083 patent/WO2010065447A2/en not_active Ceased
- 2009-11-30 MX MX2011005713A patent/MX2011005713A/es active IP Right Grant
- 2009-11-30 UA UAA201108205A patent/UA106217C2/ru unknown
- 2009-12-05 SA SA109300715A patent/SA109300715B1/ar unknown
2011
- 2011-05-09 IL IL212799A patent/IL212799A/en not_active IP Right Cessation
- 2011-05-09 IL IL212796A patent/IL212796A0/en unknown
- 2011-05-12 ZA ZA2011/03497A patent/ZA201103497B/en unknown
- 2011-06-16 EC EC2011011135A patent/ECSP11011135A/es unknown
- 2011-06-17 CO CO11075843A patent/CO6382158A2/es active IP Right Grant
2013
- 2013-12-16 US US14/107,175 patent/US20140107163A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ES2403022T3 (es)	2013-05-13
KR20110094100A (ko)	2011-08-19
JP5615836B2 (ja)	2014-10-29
UA106217C2 (en)	2014-08-11
EP2358705A1 (en)	2011-08-24
HK1157778A1 (en)	2012-07-06
MX2011005713A (es)	2011-06-17
MY159040A (en)	2016-12-15
CA2744197A1 (en)	2010-06-10
EP2358670A2 (en)	2011-08-24
US20120015983A1 (en)	2012-01-19
UY32278A (es)	2011-06-30
ZA201103497B (en)	2012-01-25
AU2009322630A1 (en)	2010-06-10
SA109300715B1 (ar)	2014-06-25
CN102232072B (zh)	2014-09-24
CL2009002146A1 (es)	2010-04-30
EP2358670B1 (en)	2012-10-24
IL212799A (en)	2013-12-31
JP5698673B2 (ja)	2015-04-08
WO2010065447A3 (en)	2010-07-22
JP2012510472A (ja)	2012-05-10
EA021054B1 (ru)	2015-03-31
SG171432A1 (en)	2011-07-28
RU2507197C2 (ru)	2014-02-20
CL2009002145A1 (es)	2010-04-30
JP2012510473A (ja)	2012-05-10
CN102232072A (zh)	2011-11-02
CA2744191A1 (en)	2010-06-10
CO6382158A2 (es)	2012-02-15
BRPI0922630A2 (pt)	2016-01-05
SG171876A1 (en)	2011-07-28
RU2011127004A (ru)	2013-01-10
AR074239A1 (es)	2010-12-29
WO2010065449A1 (en)	2010-06-10
WO2010065447A2 (en)	2010-06-10
TW201024283A (en)	2010-07-01
NZ593058A (en)	2013-06-28
US20140107163A1 (en)	2014-04-17
KR20110094318A (ko)	2011-08-23
EA201170736A1 (ru)	2011-12-30
US20110269975A1 (en)	2011-11-03
US8153821B2 (en)	2012-04-10
CN102227406B (zh)	2013-07-31
MX2011005712A (es)	2011-06-17
IL212799A0 (en)	2011-07-31
CN102227406A (zh)	2011-10-26
PE20100467A1 (es)	2010-08-03
ECSP11011135A (es)	2011-07-29
IL212796A0 (en)	2011-07-31
AU2009322628A1 (en)	2010-06-10
EP2896619A1 (en)	2015-07-22
US8633227B2 (en)	2014-01-21

Legal Events

Date	Code	Title	Description
2016-10-11	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 7A ANUIDADE.
2017-02-07	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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