BRPI0922871A2 - metodos para o tratamento da esclerose múltipla usando pirazinoindóis tetracíclicos - Google Patents

metodos para o tratamento da esclerose múltipla usando pirazinoindóis tetracíclicos

Info

Publication number
BRPI0922871A2
BRPI0922871A2 BRPI0922871A BRPI0922871A BRPI0922871A2 BR PI0922871 A2 BRPI0922871 A2 BR PI0922871A2 BR PI0922871 A BRPI0922871 A BR PI0922871A BR PI0922871 A BRPI0922871 A BR PI0922871A BR PI0922871 A2 BRPI0922871 A2 BR PI0922871A2
Authority
BR
Brazil
Prior art keywords
methods
multiple sclerosis
treating multiple
tetracyclic pyrazinoindoles
pyrazinoindoles
Prior art date
Application number
BRPI0922871A
Other languages
English (en)
Inventor
Andreas Persidis
Spyros Deftereos
Original Assignee
Biovista Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovista Inc filed Critical Biovista Inc
Publication of BRPI0922871A2 publication Critical patent/BRPI0922871A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0922871A 2008-12-11 2009-12-11 metodos para o tratamento da esclerose múltipla usando pirazinoindóis tetracíclicos BRPI0922871A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12157408P 2008-12-11 2008-12-11
US23323509P 2009-08-12 2009-08-12
PCT/US2009/067673 WO2010068867A1 (en) 2008-12-11 2009-12-11 Methods for treating multiple sclerosis using tetracyclic pyrazinoindoles

Publications (1)

Publication Number Publication Date
BRPI0922871A2 true BRPI0922871A2 (pt) 2016-11-16

Family

ID=42243090

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922871A BRPI0922871A2 (pt) 2008-12-11 2009-12-11 metodos para o tratamento da esclerose múltipla usando pirazinoindóis tetracíclicos

Country Status (9)

Country Link
US (1) US20110268699A1 (pt)
EP (1) EP2375900B1 (pt)
JP (1) JP2012512165A (pt)
CN (1) CN102395275A (pt)
AU (1) AU2009324495B2 (pt)
BR (1) BRPI0922871A2 (pt)
CA (1) CA2747235C (pt)
IL (1) IL213476A0 (pt)
WO (1) WO2010068867A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012502915A (ja) 2008-09-15 2012-02-02 バイオビスタ インコーポレイテッド てんかんを治療する組成物及び方法
EP3536317A1 (en) 2009-10-30 2019-09-11 Retrotope, Inc. Alleviating oxidative stress disorders with pufa derivatives
RU2436786C1 (ru) * 2010-07-23 2011-12-20 Александр Васильевич Иващенко Замещенные индолы, противовирусный активный компонент, способ получения и применения
AU2012249920B2 (en) 2011-04-26 2017-06-15 Biojiva Llc Disorders implicating PUFA oxidation
US10058522B2 (en) 2011-04-26 2018-08-28 Retrotope, Inc. Oxidative retinal diseases
CA2834274C (en) * 2011-04-26 2021-08-03 Retrotope, Inc. Neurodegenerative disorders and muscle diseases implicating pufas
AU2012249918B2 (en) 2011-04-26 2017-06-15 Biojiva Llc Impaired energy processing disorders and mitochondrial deficiency
US20150018362A1 (en) 2012-02-27 2015-01-15 Biovista, Inc. Compositions and methods for treating mitochondrial diseases
HK1218254A1 (zh) * 2013-02-15 2017-02-10 Teva Pharmaceutical Industries Ltd. 用拉喹莫德治疗多发性硬化症
KR101521807B1 (ko) * 2014-01-20 2015-05-20 한국전자통신연구원 데이터 전송 제어 장치 및 그 방법
UA118587C2 (uk) * 2014-05-09 2019-02-11 Текнімеді Сос'Єдаді Текніку-Медісінал С.А. Фармацевтично прийнятні солі енантіомерів пірліндолу для застосування в медицині
EP3380452B1 (en) 2015-11-23 2021-03-24 Retrotope, Inc. Site-specific isotopic labeling of 1, 4-diene systems
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
AU2017319728B2 (en) 2016-08-31 2024-09-05 Mapi Pharma Ltd Depot systems comprising glatiramer acetate
MX2019010174A (es) 2017-03-26 2019-10-15 Mapi Pharma Ltd Sistemas de deposito de glatiramer para el tratamiento de formas progresivas de esclerosis multiple.
EP3520803A1 (en) * 2018-01-31 2019-08-07 Zarodex Therapeutics Limited Novel uses
CN116438187A (zh) 2020-02-21 2023-07-14 拜奥吉瓦有限责任公司 多不饱和脂肪酸及其衍生物的同位素修饰方法
US12109194B2 (en) 2021-02-05 2024-10-08 Biojiva Llc Synergistic combination therapy for treating ALS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959470A (en) * 1972-11-28 1976-05-25 Mikhail Davidovich Mashkovsky Psychotropic medicinal preparation
US5300645A (en) * 1993-04-14 1994-04-05 Eli Lilly And Company Tetrahydro-pyrido-indole
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
JPWO2004098638A1 (ja) * 2003-05-06 2006-07-13 小野薬品工業株式会社 エフェクター細胞機能阻害剤
RU2281085C2 (ru) * 2004-05-25 2006-08-10 Закрытое акционерное общество "Мастерлек" Антидепрессивные лекарственные средства для парентерального применения на основе сульфонатных солей пирлиндола
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
AU2006275694A1 (en) * 2005-07-28 2007-02-08 Bristol-Myers Squibb Company Substituted tetrahydro-1H-pyrido(4,3,b)indoles as serotonin receptor agonists and antagonists
AU2008257152A1 (en) * 2007-05-25 2008-12-04 Medivation Neurology, Inc. Methods and compositions for stimulating cells

Also Published As

Publication number Publication date
EP2375900A1 (en) 2011-10-19
AU2009324495B2 (en) 2015-12-24
IL213476A0 (en) 2011-07-31
EP2375900A4 (en) 2012-05-02
AU2009324495A1 (en) 2011-07-28
US20110268699A1 (en) 2011-11-03
EP2375900B1 (en) 2016-03-02
CN102395275A (zh) 2012-03-28
CA2747235A1 (en) 2010-06-17
WO2010068867A1 (en) 2010-06-17
JP2012512165A (ja) 2012-05-31
CA2747235C (en) 2021-02-09

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL