BRPI0922981A2 - Método para o controle do peso molecular polissacarídeo para o sorotipo 19a de streptococcus pneumoniae - Google Patents

Método para o controle do peso molecular polissacarídeo para o sorotipo 19a de streptococcus pneumoniae

Info

Publication number
BRPI0922981A2
BRPI0922981A2 BRPI0922981-7A BRPI0922981A BRPI0922981A2 BR PI0922981 A2 BRPI0922981 A2 BR PI0922981A2 BR PI0922981 A BRPI0922981 A BR PI0922981A BR PI0922981 A2 BRPI0922981 A2 BR PI0922981A2
Authority
BR
Brazil
Prior art keywords
molecular weight
streptococcus pneumoniae
weight control
pneumoniae serotype
polysaccharide molecular
Prior art date
Application number
BRPI0922981-7A
Other languages
English (en)
Inventor
Jean Heather Crinean
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of BRPI0922981A2 publication Critical patent/BRPI0922981A2/pt
Publication of BRPI0922981A8 publication Critical patent/BRPI0922981A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
BRPI0922981-7 2008-12-18 2009-12-17 método para o controle do peso molecular polissacarídeo para o sorotipo 19a de streptococcus pneumoniae BRPI0922981A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13856308P 2008-12-18 2008-12-18
PCT/US2009/068429 WO2010080486A2 (en) 2008-12-18 2009-12-17 Method for controlling streptococcus pneumoniae serotype 19a polysaccharide molecular weight

Publications (2)

Publication Number Publication Date
BRPI0922981A2 true BRPI0922981A2 (pt) 2015-08-25
BRPI0922981A8 BRPI0922981A8 (pt) 2019-11-26

Family

ID=42266457

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0922981-7 BRPI0922981A8 (pt) 2008-12-18 2009-12-17 método para o controle do peso molecular polissacarídeo para o sorotipo 19a de streptococcus pneumoniae

Country Status (18)

Country Link
US (1) US8795689B2 (pt)
EP (1) EP2379734B1 (pt)
JP (1) JP5843612B2 (pt)
KR (2) KR20110091546A (pt)
CN (1) CN102257155B (pt)
AU (1) AU2009335826B2 (pt)
BR (1) BRPI0922981A8 (pt)
CA (1) CA2743710C (pt)
DK (1) DK2379734T3 (pt)
ES (1) ES2666698T3 (pt)
HU (1) HUE037465T2 (pt)
IL (1) IL213169A (pt)
MX (1) MX2011006432A (pt)
PL (1) PL2379734T3 (pt)
PT (1) PT2379734T (pt)
RU (1) RU2511404C2 (pt)
SI (1) SI2379734T1 (pt)
WO (1) WO2010080486A2 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2749952T3 (es) * 2008-12-18 2020-03-24 Wyeth Llc Procedimiento de control del peso molecular de polisacáridos de Streptococcus pneumoniae usando carbono
US20120052088A1 (en) 2009-04-30 2012-03-01 Coley Pharmaceutical Group, Inc. Pneumococcal vaccine and uses thereof
CN104080904B (zh) * 2011-12-15 2017-06-30 血清研究所印度私人有限公司 培养细菌以提高荚膜多糖产率的新方法
RU2606022C2 (ru) 2012-09-07 2017-01-10 Ск Кемикалс Ко., Лтд. Способ получения капсульного полисахарида с пневмококковым серотипом
CN110366428B (zh) 2016-12-30 2024-05-17 Vaxcyte公司 具有非天然氨基酸的多肽-抗原缀合物
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
EP4656208A3 (en) 2017-01-31 2026-03-04 Merck Sharp & Dohme LLC Methods for making polysaccharide-protein conjugates
JP7680185B2 (ja) 2017-02-24 2025-05-20 メルク・シャープ・アンド・ドーム・エルエルシー 肺炎連鎖球菌多糖－タンパク質コンジュゲートの免疫原性の増強
US10729763B2 (en) 2017-06-10 2020-08-04 Inventprise, Llc Mixtures of polysaccharide-protein pegylated compounds
WO2018227177A1 (en) 2017-06-10 2018-12-13 Inventprise, Llc Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity
MX394768B (es) 2017-09-07 2025-03-21 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina.
MX394767B (es) * 2017-09-07 2025-03-24 Merck Sharp & Dohme Llc Polisacaridos neumococicos y su uso en conjugados de polisacarido inmunogenico con proteina transportadora.
ES3058336T3 (es) 2017-12-06 2026-03-10 Merck Sharp & Dohme Llc Composiciones que comprenden conjugados polisacárido-proteína de Streptococcus pneumoniae y métodos de uso de los mismos
US11951162B2 (en) * 2018-04-18 2024-04-09 Sk Bioscience Co., Ltd. Streptococcus pneumoniae capsular polysaccharides and immunogenic conjugate thereof
EP3788143B1 (en) 2018-04-30 2023-06-28 Merck Sharp & Dohme LLC Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
US12144855B2 (en) 2018-04-30 2024-11-19 Merck Sharp & Dohme Llc Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates from lyospheres
EP3787673A4 (en) 2018-04-30 2022-04-27 Merck Sharp & Dohme Corp. Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates
CR20210333A (es) 2018-12-19 2021-08-18 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacárido de streptococcus pneumoniae con proteína y sus métodos de uso
WO2022035816A1 (en) 2020-08-10 2022-02-17 Inventprise, Llc Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f

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CA1115210A (en) 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4221906A (en) 1979-03-19 1980-09-09 American Cyanamid Company Stabilization of pneumococcal polysaccharides
US4242501A (en) 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
FR2495939B1 (fr) 1980-12-11 1985-10-11 Merieux Inst Procede de purification de polyosides de streptococcus pneumoniae et vaccin a base de polyosides ainsi purifies
BE889979A (fr) 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US4686102A (en) 1984-04-12 1987-08-11 American Cyanamid Company Multivalent pneumococcal vaccine and preparation thereof
CA2059693C (en) * 1991-01-28 2003-08-19 Peter J. Kniskern Polysaccharide antigens from streptococcus pneumoniae
CA2059692C (en) 1991-01-28 2004-11-16 Peter J. Kniskern Pneumoccoccal polysaccharide conjugate vaccine
US5314822A (en) * 1992-10-15 1994-05-24 Merck & Co., Inc. Method of clonal growth of Streptococcus pneumoniae
US5714354A (en) 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
US6146902A (en) 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
AU2001245795B2 (en) * 2000-03-16 2005-07-28 The Children's Hospital Of Philadelphia Modulating production of pneumococcal capsular polysaccharide
US6743610B2 (en) 2001-03-30 2004-06-01 The University Of Chicago Method to produce succinic acid from raw hydrolysates
ITTS20010013A1 (it) 2001-06-04 2002-12-04 Ct Ricerche Poly Tec H A R L S Nuovi derivati di ialuronano.
DE602004025951D1 (de) 2003-09-11 2010-04-22 Staat Der Nederlanden Vert Doo Verfahren zur herstellung eines kapselpolysaccharids zur verwendung in konjugat-impfstoffen
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
EP3311836A1 (en) 2005-04-08 2018-04-25 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
US20070184072A1 (en) 2005-04-08 2007-08-09 Wyeth Multivalent pneumococcal polysaccharide-protein conjugate composition
US7955605B2 (en) 2005-04-08 2011-06-07 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
CN101155833B (zh) 2005-04-08 2011-04-20 惠氏公司 通过pH操作将污染物与肺炎链球菌多糖分离
GB0522303D0 (en) * 2005-11-01 2005-12-07 Chiron Srl Culture method
DK2074221T3 (da) 2006-10-10 2010-09-06 Wyeth Llc Forbedrede fremgangsmåder til separation af streptococcus pneumoniae type 3 polysakkarider
US7860500B2 (en) * 2006-10-27 2010-12-28 Motorola, Inc. Method and apparatus for determining appropriate channels for communication
CN101663327B (zh) 2007-03-23 2014-05-07 惠氏公司 产生肺炎链球菌(streptococcus pneumoniae)荚膜多糖的缩短的纯化方法
ES2749952T3 (es) 2008-12-18 2020-03-24 Wyeth Llc Procedimiento de control del peso molecular de polisacáridos de Streptococcus pneumoniae usando carbono

Also Published As

Publication number Publication date
EP2379734B1 (en) 2018-03-21
ES2666698T3 (es) 2018-05-07
AU2009335826A1 (en) 2010-07-15
KR20130136011A (ko) 2013-12-11
WO2010080486A3 (en) 2010-11-04
BRPI0922981A8 (pt) 2019-11-26
SI2379734T1 (en) 2018-05-31
RU2011128564A (ru) 2013-01-27
EP2379734A2 (en) 2011-10-26
WO2010080486A2 (en) 2010-07-15
HK1163750A1 (zh) 2012-09-14
US20100158953A1 (en) 2010-06-24
RU2511404C2 (ru) 2014-04-10
CA2743710C (en) 2017-01-24
US8795689B2 (en) 2014-08-05
CN102257155B (zh) 2016-03-02
CA2743710A1 (en) 2010-07-15
AU2009335826B2 (en) 2013-10-31
DK2379734T3 (en) 2018-04-23
IL213169A0 (en) 2011-07-31
MX2011006432A (es) 2011-09-29
PL2379734T3 (pl) 2018-08-31
KR20110091546A (ko) 2011-08-11
IL213169A (en) 2015-02-26
CN102257155A (zh) 2011-11-23
HUE037465T2 (hu) 2018-09-28
KR101593770B1 (ko) 2016-02-15
JP5843612B2 (ja) 2016-01-13
JP2012512660A (ja) 2012-06-07
PT2379734T (pt) 2018-04-27

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B25G Requested change of headquarter approved

Owner name: WYETH LLC (US)