BRPI0923155A2 - scfcs de ligação a sparc - Google Patents

scfcs de ligação a sparc

Info

Publication number
BRPI0923155A2
BRPI0923155A2 BRPI0923155A BRPI0923155A BRPI0923155A2 BR PI0923155 A2 BRPI0923155 A2 BR PI0923155A2 BR PI0923155 A BRPI0923155 A BR PI0923155A BR PI0923155 A BRPI0923155 A BR PI0923155A BR PI0923155 A2 BRPI0923155 A2 BR PI0923155A2
Authority
BR
Brazil
Prior art keywords
scfcs
sparc binding
sparc
binding
binding scfcs
Prior art date
Application number
BRPI0923155A
Other languages
English (en)
Inventor
Trieu Vuong
Original Assignee
Abraxis Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abraxis Bioscience Llc filed Critical Abraxis Bioscience Llc
Publication of BRPI0923155A2 publication Critical patent/BRPI0923155A2/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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    • A61K49/0017Fluorescence in vivo
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/70521CD28, CD152
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
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    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07K2317/622Single chain antibody (scFv)
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    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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BRPI0923155A 2008-12-05 2009-12-07 scfcs de ligação a sparc BRPI0923155A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12022808P 2008-12-05 2008-12-05
PCT/US2009/067032 WO2010065969A1 (en) 2008-12-05 2009-12-07 Sparc binding scfcs

Publications (1)

Publication Number Publication Date
BRPI0923155A2 true BRPI0923155A2 (pt) 2018-10-23

Family

ID=42233653

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0922790A BRPI0922790A2 (pt) 2008-12-05 2009-12-07 peptídeos de ligação sparc e usos dos mesmos
BRPI0923155A BRPI0923155A2 (pt) 2008-12-05 2009-12-07 scfcs de ligação a sparc

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EP2381952A4 (en) 2012-05-30
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RU2011127456A (ru) 2013-01-10
CN104174025B (zh) 2017-01-11
MX2011005966A (es) 2011-06-30
CN104940928B (zh) 2018-03-30
EP3059247A1 (en) 2016-08-24
ZA201104122B (en) 2012-02-29
US20140341905A1 (en) 2014-11-20
RU2011127454A (ru) 2013-01-10
CN102272159A (zh) 2011-12-07
RU2491085C2 (ru) 2013-08-27
MX2011005967A (es) 2011-06-30
US8445637B2 (en) 2013-05-21
US20130315823A1 (en) 2013-11-28
WO2010065969A1 (en) 2010-06-10
JP2012511032A (ja) 2012-05-17
EP2376534A4 (en) 2012-05-30
CA2745923A1 (en) 2010-06-10
US20160304592A1 (en) 2016-10-20
JP5580329B2 (ja) 2014-08-27
CN104940928A (zh) 2015-09-30
AU2009322130A1 (en) 2011-06-23
CN102272159B (zh) 2015-06-03
US20140341904A1 (en) 2014-11-20
CA2808320A1 (en) 2010-06-10
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JP2012511030A (ja) 2012-05-17
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CN102281890A (zh) 2011-12-14
EP2381952B1 (en) 2016-03-09
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NZ593281A (en) 2012-12-21
CA2745904C (en) 2014-07-08
US9308279B2 (en) 2016-04-12
RU2477728C1 (ru) 2013-03-20
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CN106905429A (zh) 2017-06-30
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NZ602824A (en) 2014-05-30
BRPI0922790A2 (pt) 2018-11-06
US9314537B2 (en) 2016-04-19
ES2647351T3 (es) 2017-12-21
NZ623264A (en) 2015-09-25
KR20140071501A (ko) 2014-06-11
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US8809507B2 (en) 2014-08-19
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AU2009322130B2 (en) 2013-06-13
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US8821836B2 (en) 2014-09-02
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